Cdkn1c (cyclin-dependent kinase inhibitor 1C) - Rat Genome Database

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Gene: Cdkn1c (cyclin-dependent kinase inhibitor 1C) Rattus norvegicus
Analyze
Symbol: Cdkn1c
Name: cyclin-dependent kinase inhibitor 1C
RGD ID: 727892
Description: Predicted to enable protein kinase inhibitor activity. Predicted to be involved in several processes, including negative regulation of phosphorylation; positive regulation of transforming growth factor beta receptor signaling pathway; and regulation of DNA-templated transcription. Predicted to act upstream of or within several processes, including embryonic placenta morphogenesis; regulation of gene expression; and uterus development. Predicted to be located in cytoplasm and nucleus. Used to study lung cancer. Biomarker of lung cancer. Human ortholog(s) of this gene implicated in Beckwith-Wiedemann syndrome; IMAGe syndrome; and hyperinsulinism. Orthologous to human CDKN1C (cyclin dependent kinase inhibitor 1C); PARTICIPATES IN G1/S transition pathway; cell cycle pathway, mitotic; INTERACTS WITH 17alpha-ethynylestradiol; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: cyclin-dependent kinase inhibitor 1C (P57); cyclin-dependent kinase inhibitor 1C, p57; cyclin-dependent kinase inhibitor p57; Kip2; LOC361683; MGC112585; p57; p57KIP2; p57KIP2 A3sh
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21198,655,394 - 198,658,097 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1198,655,407 - 198,658,048 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1207,034,074 - 207,036,728 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01214,120,600 - 214,123,254 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01206,794,746 - 206,797,400 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01216,661,067 - 216,663,791 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1216,661,080 - 216,663,721 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01223,521,098 - 223,524,053 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41203,835,215 - 203,837,844 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1196,223,813 - 196,226,467 (-)NCBICelera
Cytogenetic Map1q42NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(1->4)-beta-D-glucan  (ISO)
1,1-dichloroethene  (ISO)
1-chloro-2,4-dinitrobenzene  (ISO)
17alpha-ethynylestradiol  (EXP)
17beta-estradiol  (EXP,ISO)
2,2',5,5'-tetrachlorobiphenyl  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,6-dinitrotoluene  (EXP)
2-hydroxypropanoic acid  (ISO)
3-isobutyl-1-methyl-7H-xanthine  (ISO)
4,4'-diaminodiphenylmethane  (ISO)
4,4'-sulfonyldiphenol  (ISO)
4-(ethoxymethylene)-2-phenyloxazol-5-one  (ISO)
4-hydroxynon-2-enal  (ISO)
4-nonylphenol  (ISO)
5-aza-2'-deoxycytidine  (ISO)
5-azacytidine  (ISO)
5-fluorouracil  (ISO)
6-propyl-2-thiouracil  (EXP)
9-cis-retinoic acid  (ISO)
acetamide  (EXP)
acrylamide  (EXP,ISO)
aflatoxin B1  (EXP)
all-trans-4-oxoretinoic acid  (ISO)
all-trans-retinoic acid  (ISO)
ammonium chloride  (EXP)
amphibole asbestos  (ISO)
anthracen-2-amine  (EXP)
antirheumatic drug  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
arsenite(3-)  (ISO)
atrazine  (EXP,ISO)
benzene  (ISO)
benzo[a]pyrene  (EXP,ISO)
benzo[a]pyrene diol epoxide I  (ISO)
benzo[b]fluoranthene  (ISO)
berberine  (ISO)
beta-naphthoflavone  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
buta-1,3-diene  (ISO)
butanal  (ISO)
cadmium atom  (ISO)
cadmium dichloride  (ISO)
calycosin  (ISO)
carbon nanotube  (ISO)
carmustine  (ISO)
chloroprene  (ISO)
chlorpyrifos  (ISO)
choline  (ISO)
cisplatin  (ISO)
copper atom  (ISO)
copper(0)  (ISO)
copper(II) sulfate  (ISO)
coumestrol  (ISO)
crocidolite asbestos  (ISO)
Cuprizon  (EXP)
cyclophosphamide  (ISO)
cyclosporin A  (ISO)
cypermethrin  (ISO)
cytarabine  (ISO)
dexamethasone  (ISO)
dextran sulfate  (ISO)
diazinon  (EXP,ISO)
dibutyl phthalate  (EXP)
dieldrin  (EXP)
diethylstilbestrol  (ISO)
dimethylarsinic acid  (EXP)
dinophysistoxin 1  (ISO)
dioxygen  (ISO)
disodium selenite  (ISO)
disulfiram  (ISO)
diuron  (EXP)
divanadium pentaoxide  (ISO)
dorsomorphin  (ISO)
doxorubicin  (ISO)
elemental selenium  (ISO)
emodin  (ISO)
ethanol  (ISO)
fenamidone  (ISO)
folic acid  (ISO)
formaldehyde  (ISO)
genistein  (ISO)
glycidol  (EXP)
harmine  (ISO)
hydrogen peroxide  (ISO)
hydroquinone  (ISO)
hydroxyurea  (ISO)
indometacin  (ISO)
iron atom  (EXP)
iron(0)  (EXP)
isoliquiritigenin  (ISO)
isotretinoin  (ISO)
L-methionine  (ISO)
lamivudine  (ISO)
Licochalcone B  (ISO)
linalool  (ISO)
lipopolysaccharide  (ISO)
lithium chloride  (ISO)
manganese(II) chloride  (EXP)
menadione  (ISO)
methoxychlor  (EXP)
methylmercury chloride  (ISO)
methylseleninic acid  (ISO)
mono(2-ethylhexyl) phthalate  (ISO)
monobenzyl phthalate  (ISO)
monoethyl phthalate  (ISO)
monosodium L-glutamate  (ISO)
N-methyl-4-phenylpyridinium  (EXP)
N-nitrosodiethylamine  (ISO)
nickel atom  (ISO)
nickel subsulfide  (EXP)
oxaliplatin  (EXP)
p-anisidine  (ISO)
paracetamol  (ISO)
paraquat  (EXP,ISO)
pentanal  (ISO)
perfluorooctane-1-sulfonic acid  (EXP,ISO)
phorbol 13-acetate 12-myristate  (ISO)
pioglitazone  (ISO)
pirinixic acid  (ISO)
progesterone  (EXP,ISO)
pyrogallol  (ISO)
quercetin  (ISO)
rac-lactic acid  (ISO)
reactive oxygen species  (ISO)
resveratrol  (ISO)
SB 431542  (ISO)
selenium atom  (ISO)
serpentine asbestos  (ISO)
silicon dioxide  (ISO)
simvastatin  (ISO)
sodium arsenite  (ISO)
sodium dodecyl sulfate  (ISO)
sodium fluoride  (EXP)
sotorasib  (ISO)
sterigmatocystin  (EXP)
sulforaphane  (ISO)
temozolomide  (ISO)
tert-butyl hydroperoxide  (ISO)
testosterone  (ISO)
tetrachloromethane  (EXP)
theophylline  (ISO)
thimerosal  (ISO)
thioacetamide  (EXP)
titanium dioxide  (ISO)
toluene 2,4-diisocyanate  (ISO)
topotecan  (EXP,ISO)
trametinib  (ISO)
trichostatin A  (ISO)
triclosan  (ISO)
trimellitic anhydride  (ISO)
triptonide  (ISO)
troglitazone  (ISO)
tunicamycin  (ISO)
urethane  (ISO)
valproic acid  (EXP,ISO)
vinclozolin  (EXP)
vorinostat  (ISO)
zearalenone  (ISO)
zidovudine  (ISO)
zinc atom  (ISO)
zinc(0)  (ISO)
zoledronic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cytoplasm  (ISO)
nucleus  (ISO)

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. The degradation of cell cycle regulators by SKP2/CKS1 ubiquitin ligase is genetically controlled in rodent liver cancer and contributes to determine the susceptibility to the disease. Calvisi DF, etal., Int J Cancer. 2009 Jun 16.
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
4. Down-regulation of the cyclin-dependent kinase inhibitor p57 is mediated by Jab1/Csn5 in hepatocarcinogenesis. Guo H, etal., Hepatology. 2016 Mar;63(3):898-913. doi: 10.1002/hep.28372. Epub 2016 Jan 14.
5. p57(Kip2) cooperates with Nurr1 in developing dopamine cells. Joseph B, etal., Proc Natl Acad Sci U S A 2003 Dec 23;100(26):15619-24. Epub 2003 Dec 11.
6. p57(KIP2) expression in normal islet cells and in hyperinsulinism of infancy. Kassem SA, etal., Diabetes. 2001 Dec;50(12):2763-9.
7. Epigenetic silencing of cell cycle regulatory genes during 3-methylcholanthrene and diethylnitrosamine-induced multistep rat lung cancer. Liu WB, etal., Mol Carcinog. 2010 Jun;49(6):556-65. doi: 10.1002/mc.20621.
8. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
9. NCBI rat LocusLink and RefSeq merged data October 15, 2003 NCBI rat LocusLink and RefSeq merged data October 15, 2003
10. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
11. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
12. GOA pipeline RGD automated data pipeline
13. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
14. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
15. The Pezcoller lecture: cancer cell cycles revisited. Sherr CJ Cancer Res. 2000 Jul 15;60(14):3689-95.
16. Changes in polypeptide pattern of rat liver cells during chemical hepatocarcinogenesis. Sugioka Y, etal., Cancer Res. 1985 Jan;45(1):365-78.
Additional References at PubMed
PMID:9784491   PMID:11737597   PMID:11746698   PMID:12477932   PMID:12947022   PMID:15889154   PMID:16259944   PMID:16943770   PMID:17553990   PMID:18721488   PMID:18814313   PMID:19170105  
PMID:19228596   PMID:19276117   PMID:19458044   PMID:19934273   PMID:21245411   PMID:21729874   PMID:22127597   PMID:22874918   PMID:25596037   PMID:25979571   PMID:27216774   PMID:29693157  


Genomics

Comparative Map Data
Cdkn1c
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21198,655,394 - 198,658,097 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1198,655,407 - 198,658,048 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1207,034,074 - 207,036,728 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01214,120,600 - 214,123,254 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01206,794,746 - 206,797,400 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01216,661,067 - 216,663,791 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1216,661,080 - 216,663,721 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01223,521,098 - 223,524,053 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41203,835,215 - 203,837,844 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1196,223,813 - 196,226,467 (-)NCBICelera
Cytogenetic Map1q42NCBI
CDKN1C
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38112,883,218 - 2,885,775 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl112,883,213 - 2,885,775 (-)EnsemblGRCh38hg38GRCh38
GRCh37112,904,448 - 2,907,005 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36112,861,441 - 2,863,551 (-)NCBINCBI36Build 36hg18NCBI36
Build 34112,861,440 - 2,863,537NCBI
Celera112,939,161 - 2,941,708 (-)NCBICelera
Cytogenetic Map11p15.4NCBI
HuRef112,692,706 - 2,695,485 (-)NCBIHuRef
CHM1_1112,903,367 - 2,905,909 (-)NCBICHM1_1
T2T-CHM13v2.0112,972,459 - 2,975,017 (-)NCBIT2T-CHM13v2.0
Cdkn1c
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm397143,012,076 - 143,014,735 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl7143,012,076 - 143,014,787 (-)EnsemblGRCm39 Ensembl
GRCm387143,458,339 - 143,461,059 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl7143,458,339 - 143,461,050 (-)EnsemblGRCm38mm10GRCm38
MGSCv377150,644,244 - 150,646,955 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv367143,267,730 - 143,270,386 (-)NCBIMGSCv36mm8
Celera7143,214,045 - 143,216,756 (-)NCBICelera
Cytogenetic Map7F5NCBI
cM Map788.22NCBI
Cdkn1c
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_00495542214,576,971 - 14,578,868 (-)NCBIChiLan1.0ChiLan1.0
CDKN1C
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1114,506,267 - 4,508,860 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0112,908,537 - 2,911,134 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1112,937,122 - 2,938,022 (-)NCBIpanpan1.1PanPan1.1panPan2
CDKN1C
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11846,860,636 - 46,861,697 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1845,470,401 - 45,472,911 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01847,540,589 - 47,543,107 (-)NCBIROS_Cfam_1.0
UMICH_Zoey_3.11846,985,894 - 46,988,403 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01846,568,604 - 46,571,113 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01847,315,144 - 47,317,648 (-)NCBIUU_Cfam_GSD_1.0
Cdkn1c
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244049473,080,687 - 3,082,266 (-)NCBIHiC_Itri_2
SpeTri2.0NW_0049367941,023,891 - 1,025,470 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CDKN1C
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl22,019,830 - 2,021,853 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.122,019,391 - 2,022,092 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
CDKN1C
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.112,696,382 - 2,699,054 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl12,696,233 - 2,699,028 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603899,897,211 - 99,899,861 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Cdkn1c
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462476715,642,012 - 15,645,664 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462476715,642,991 - 15,645,648 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Cdkn1c
9 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:228
Count of miRNA genes:95
Interacting mature miRNAs:114
Transcripts:ENSRNOT00000027885, ENSRNOT00000073862
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
10059597Bp377Blood pressure QTL 3773.420.025arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)132737458199368955Rat
634314Niddm44Non-insulin dependent diabetes mellitus QTL 44blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)149393289199050459Rat
1578780Cm52Cardiac mass QTL 523.30.0001heart mass (VT:0007028)heart wet weight (CMO:0000069)181591954219808434Rat
731168Bp154Blood pressure QTL 1543.4arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)194642644214537671Rat
1354591Cm36Cardiac mass QTL 364.1heart left ventricle mass (VT:0007031)calculated heart weight (CMO:0000073)1102813953201278233Rat
1354615Cm32Cardiac mass QTL 325.2heart left ventricle mass (VT:0007031)heart left ventricle wet weight (CMO:0000071)1102813953201278233Rat
1354606Bp246Blood pressure QTL 2463.6arterial blood pressure trait (VT:2000000)pulse pressure (CMO:0000292)1102813953218753816Rat
7794788Mcs32Mammary carcinoma susceptibility QTL 322.61mammary gland integrity trait (VT:0010552)mammary tumor incidence/prevalence measurement (CMO:0000946)1115540693238914717Rat
7421630Bp362Blood pressure QTL 3620.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1118608292241799120Rat
631205Bp196Blood pressure QTL 19640.0001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1118944897199050459Rat
631549Bp89Blood pressure QTL 895.7arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1123350581201284552Rat
1598853Memor3Memory QTL 34.5exploratory behavior trait (VT:0010471)total horizontal distance resulting from voluntary locomotion in an experimental apparatus (CMO:0001443)1143506580212458660Rat
737828Hcas3Hepatocarcinoma susceptibility QTL 34.9liver integrity trait (VT:0010547)liver tumorous lesion volume to total liver volume ratio (CMO:0001082)1144267353222987745Rat
2302378Insul11Insulin level QTL 113.25blood insulin amount (VT:0001560)serum insulin level (CMO:0000358)1144267353251128347Rat
7771612Cm80Cardiac mass QTL 808.4heart left ventricle mass (VT:0007031)heart left ventricle weight (CMO:0000776)1149448574221264292Rat
724531Uae5Urinary albumin excretion QTL 54urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)1150700142252085212Rat
1578759Uae30Urinary albumin excretion QTL 303.30.003urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)1150700247252085048Rat
1578778Pur4Proteinuria QTL 43.30.003urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)1150700247252085048Rat
1354602Bw35Body weight QTL 3512.2body mass (VT:0001259)body weight (CMO:0000012)1151162512201278233Rat
1354620Kidm19Kidney mass QTL 194kidney mass (VT:0002707)calculated kidney weight (CMO:0000160)1151162512201278233Rat
1354634Kidm12Kidney mass QTL 123.9kidney mass (VT:0002707)right kidney wet weight (CMO:0000082)1151162512201278233Rat
1354636Lmblg1Limb length QTL 16.4tibia length (VT:0004357)tibia length (CMO:0000450)1151162512201278233Rat
1354610Bw34Body weight QTL 344.1body mass (VT:0001259)body weight (CMO:0000012)1151162512256448636Rat
1354646Kidm18Kidney mass QTL 185.7kidney mass (VT:0002707)calculated kidney weight (CMO:0000160)1151162512256448636Rat
1354661Bw33Body weight QTL 335.2body mass (VT:0001259)body weight (CMO:0000012)1151162512256448636Rat
1358886Bp260Blood pressure QTL 2603.67arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1151162766225824951Rat
1549837Hcar15Hepatocarcinoma resistance QTL 150.05liver integrity trait (VT:0010547)liver tumorous lesion number (CMO:0001068)1153136852260522016Rat
2303622Vencon6Ventilatory control QTL 60.001respiration trait (VT:0001943)respiration rate (CMO:0000289)1154561505199561505Rat
4889428Stresp24Stress response QTL 240.05heart pumping trait (VT:2000009)absolute change in electrocardiographic low frequency R-R spectral component to high frequency R-R spectral component ratio (CMO:0002162)1155866514200866514Rat
1354618Kidm15Kidney mass QTL 155kidney mass (VT:0002707)left kidney wet weight (CMO:0000083)1156677124201278233Rat
2312420Pur17Proteinuria QTL 177.10.0001urine protein amount (VT:0005160)urine total protein excretion rate (CMO:0000756)1156677124218753816Rat
1354580Scort1Serum corticosterone level QTL 13.4blood corticosterone amount (VT:0005345)blood corticosterone level (CMO:0001172)1156677124256448636Rat
61347Bp197Blood pressure QTL 1974.2arterial blood pressure trait (VT:2000000)blood pressure measurement (CMO:0000003)1158633083203633083Rat
2292222Bp307Blood pressure QTL 3073.060.0014arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1164310393213533942Rat
2292220Bp306Blood pressure QTL 3063.470.00087arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1164310393243914901Rat
619613Bp77Blood pressure QTL 770.01arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1164747424209747424Rat
619613Bp77Blood pressure QTL 770.01arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)1164747424209747424Rat
1354653Despr9Despair related QTL 90.00019locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)1167909849212909849Rat
61341Bp26Blood pressure QTL 26arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1169537671214537671Rat
724562Rends1Renal damage susceptibility QTL 10.05kidney glomerulus integrity trait (VT:0010546)index of glomerular damage (CMO:0001135)1169537671214537671Rat
1358294Bw37Body weight QTL 3750.000011body mass (VT:0001259)body weight (CMO:0000012)1171310381216310381Rat
2293689Bss47Bone structure and strength QTL 477.250.0001lumbar vertebra size trait (VT:0010518)lumbar vertebra trabecular cross-sectional area (CMO:0001692)1171629477216629477Rat
2293693Bss22Bone structure and strength QTL 2233.520.0001femur morphology trait (VT:0000559)femur cross-sectional area (CMO:0001661)1171629477216629477Rat
2300161Bmd43Bone mineral density QTL 438.40.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)1171629477216629477Rat
2300174Bmd42Bone mineral density QTL 428.40.0001lumbar vertebra mineral mass (VT:0010511)bone mineral density (CMO:0001226)1171629477216629477Rat
2300187Bmd41Bone mineral density QTL 418.90.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)1171629477216629477Rat
2293654Bss30Bone structure and strength QTL 3032.650.0001femur strength trait (VT:0010010)femur midshaft polar moment of inertia (CMO:0001669)1171629477216629477Rat
2293673Bss27Bone structure and strength QTL 2718.630.0001femur morphology trait (VT:0000559)femur midshaft cortical cross-sectional area (CMO:0001663)1171629477216629477Rat
2293677Bss41Bone structure and strength QTL 419.380.0001lumbar vertebra size trait (VT:0010518)lumbar vertebra cross-sectional area (CMO:0001689)1171629477216629477Rat
1549830Bss1Bone structure and strength QTL 14.8femur strength trait (VT:0010010)femur ultimate force (CMO:0001675)1172609619217609619Rat
631214Bw61Body weight QTL613.40.0001intramuscular adipose amount (VT:0010044)intramuscular fat area (CMO:0001162)1173108781218108781Rat
70163Bw20Body weight QTL 205.1body mass (VT:0001259)body weight (CMO:0000012)1174133260219133260Rat
738032Hcas5Hepatocarcinoma susceptibility QTL 53.12liver integrity trait (VT:0010547)liver tumorous lesion number (CMO:0001068)1176426412257976495Rat
1600380Niddm70Non-insulin dependent diabetes mellitus QTL 703.10.0008blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)1176550523221550523Rat
10059600Bp378Blood pressure QTL 3783.080.05arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1176869060221869060Rat
1354624Cm35Cardiac mass QTL355.7heart left ventricle mass (VT:0007031)calculated heart weight (CMO:0000073)1177227632256448636Rat
1354652Kidm20Kidney mass QTL 204.3kidney mass (VT:0002707)calculated kidney weight (CMO:0000160)1177227632256448636Rat
1558658Bw59Body weight QTL 593.50.0003body mass (VT:0001259)body weight (CMO:0000012)1178784622223784622Rat
634321Hc1Hypercalciuria QTL 12.91urine calcium amount (VT:0002985)urine calcium excretion rate (CMO:0000763)1178810256240830002Rat
1578763Kidm29Kidney mass QTL 293.30.0001kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)1179567751260522016Rat
1302787Stl25Serum triglyceride level QTL 252.70.0073blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)1180359209210702199Rat
6903303Scl34Serum cholesterol QTL 342.50.0033blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)1180359209218108781Rat
737977Bp160Blood pressure QTL 1600.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1181133855226133855Rat
724559Pancm1Pancreatic morphology QTL 17.1islet of Langerhans morphology trait (VT:0005215)pancreatic islet damage composite score (CMO:0001156)1181759564214537555Rat
2293083Iddm25Insulin dependent diabetes mellitus QTL 254.18blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)1181829673224569684Rat
634312Bp143Blood pressure QTL 14330.0002arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1182623426219932796Rat
8655655Arrd2Age-related retinal degeneration QTL 27.79retinal layer morphology trait (VT:0003727)percentage of study population developing retinopathy during a period of time (CMO:0002453)1183970203243914901Rat
8655855Arrd3Age-related retinal degeneration QTL 33.07lens clarity trait (VT:0001304)cataract incidence/prevalence measurement (CMO:0001585)1183970203243914901Rat
631838Niddm36Non-insulin dependent diabetes mellitus QTL 360.01insulin secretion trait (VT:0003564)calculated pancreatic islet insulin release measurement (CMO:0001217)1184550676229550676Rat
1300145Rf7Renal function QTL 72.96urine creatinine amount (VT:0010540)urine creatinine level (CMO:0000125)1185145134221264292Rat
1359018Hrtrt20Heart rate QTL 203.08heart pumping trait (VT:2000009)heart rate (CMO:0000002)1185356336202902618Rat
2312564Glom18Glomerulus QTL 182.40.003kidney glomerulus morphology trait (VT:0005325)index of glomerular damage (CMO:0001135)1185356336231689108Rat
1582206Kidm33Kidney mass QTL 336.9kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)1188377360224054420Rat
6480780Insul18Insulin level QTL 184.11blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)1189607473200611765Rat
1358898Bp255Blood pressure QTL 2553.6arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1191019702246062233Rat
10059590Kidm44Kidney mass QTL 443.420.025kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)1191033875236033875Rat
631260Tcas2Tongue tumor susceptibility QTL 24.93tongue integrity trait (VT:0010553)number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)1192485903199050587Rat
1358191Ept10Estrogen-induced pituitary tumorigenesis QTL 103.8pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)1192825253243914732Rat
8552891Epfw5Epididymal fat weight QTL 54.4epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)1193113876238113876Rat
634338Hcar4Hepatocarcinoma resistance QTL 44.6liver integrity trait (VT:0010547)liver tumorous lesion number to liver area ratio (CMO:0001210)1193422268214537671Rat
1600388Niddm67Non-insulin dependent diabetes mellitus QTL 675.840.000004blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)1195804352257091168Rat
1600395Niddm69Non-insulin dependent diabetes mellitus QTL 694.140.0002blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)1195804352257091168Rat
1600396Niddm68Non-insulin dependent diabetes mellitus QTL 684.970.0003blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)1195804352257091168Rat
631658Cm7Cardiac mass QTL 75.320.0001aorta mass (VT:0002845)aorta weight (CMO:0000076)1196248093241248093Rat
1358292Cm37Cardiac mass QTL 376.20.00000081heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)1196248093241248093Rat
6480783Insul19Insulin level QTL 194.33blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)1197489281200611765Rat
1600374Mcs17Mammary carcinoma susceptibility QTL 173mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)1197670404242670404Rat
1641926Teswt2Testicular weight QTL 22.82testis mass (VT:1000644)both testes wet weight (CMO:0000175)1197697768238755659Rat
2302375Bw83Body weight QTL 834.870.0002body mass (VT:0001259)body weight (CMO:0000012)1197697768242697768Rat
61376Bp42Blood pressure QTL 4223.4arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1197814409242814409Rat
1298084Thym4Thymus enlargement QTL 410.68thymus mass (VT:0004954)thymus weight to body weight ratio (CMO:0000612)1197814409242814409Rat
1357335Bw39Body weight QTL 393.3body mass (VT:0001259)body weight (CMO:0000012)1197814409242814409Rat
1331790Bp201Blood pressure QTL 2013.127arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1198211513225126682Rat

Markers in Region
PMC307617P1  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21198,655,877 - 198,656,075 (+)MAPPERmRatBN7.2
Rnor_6.01216,661,551 - 216,661,748NCBIRnor6.0
Rnor_5.01223,521,582 - 223,521,779UniSTSRnor5.0
RGSC_v3.41203,835,699 - 203,835,896UniSTSRGSC3.4
Celera1196,224,297 - 196,224,494UniSTS
Cytogenetic Map1q42UniSTS
UniSTS:141311  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21198,655,835 - 198,656,047 (+)MAPPERmRatBN7.2
Rnor_6.01216,661,509 - 216,661,720NCBIRnor6.0
Rnor_5.01223,521,540 - 223,521,751UniSTSRnor5.0
RGSC_v3.41203,835,657 - 203,835,868UniSTSRGSC3.4
Celera1196,224,255 - 196,224,466UniSTS
Cytogenetic Map1q42UniSTS
BI285996  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21198,659,744 - 198,659,943 (+)MAPPERmRatBN7.2
Rnor_6.01216,665,418 - 216,665,616NCBIRnor6.0
Rnor_5.01223,525,669 - 223,525,867UniSTSRnor5.0
RGSC_v3.41203,839,541 - 203,839,739UniSTSRGSC3.4
Celera1196,228,164 - 196,228,362UniSTS
Cytogenetic Map1q42UniSTS
PMC187562P1  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21198,657,980 - 198,658,371 (+)MAPPERmRatBN7.2
Rnor_6.01216,663,654 - 216,664,044NCBIRnor6.0
Rnor_5.01223,523,905 - 223,524,295UniSTSRnor5.0
RGSC_v3.41203,837,777 - 203,838,167UniSTSRGSC3.4
Celera1196,226,400 - 196,226,790UniSTS
Cytogenetic Map1q42UniSTS
UniSTS:265486  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21198,656,918 - 198,657,523 (+)MAPPERmRatBN7.2
Rnor_6.01216,662,592 - 216,663,196NCBIRnor6.0
Rnor_5.01223,522,623 - 223,523,447UniSTSRnor5.0
RGSC_v3.41203,836,740 - 203,837,319UniSTSRGSC3.4
Celera1196,225,338 - 196,225,942UniSTS
Cytogenetic Map1q42UniSTS
MARC_54883-54884:1155673702:1  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21198,657,463 - 198,658,048 (+)MAPPERmRatBN7.2
Rnor_6.01216,663,137 - 216,663,721NCBIRnor6.0
Rnor_5.01223,523,388 - 223,523,972UniSTSRnor5.0
RGSC_v3.41203,837,260 - 203,837,844UniSTSRGSC3.4
Celera1196,225,883 - 196,226,467UniSTS
Cytogenetic Map1q42UniSTS
UniSTS:470552  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21198,657,162 - 198,657,938 (+)MAPPERmRatBN7.2
Rnor_6.01216,662,836 - 216,663,611NCBIRnor6.0
Rnor_5.01223,522,867 - 223,523,862UniSTSRnor5.0
RGSC_v3.41203,836,984 - 203,837,734UniSTSRGSC3.4
Celera1196,225,582 - 196,226,357UniSTS
Cytogenetic Map1q42UniSTS
Cdkn1c  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21198,655,895 - 198,656,046 (+)MAPPERmRatBN7.2
Rnor_6.01216,661,569 - 216,661,719NCBIRnor6.0
Rnor_5.01223,521,600 - 223,521,750UniSTSRnor5.0
RGSC_v3.41203,835,717 - 203,835,867UniSTSRGSC3.4
Celera1196,224,315 - 196,224,465UniSTS
Cytogenetic Map1q42UniSTS
Cdkn1c  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21198,656,285 - 198,656,937 (+)MAPPERmRatBN7.2
Rnor_6.01216,661,959 - 216,662,610NCBIRnor6.0
Rnor_5.01223,521,990 - 223,522,641UniSTSRnor5.0
RGSC_v3.41203,836,107 - 203,836,758UniSTSRGSC3.4
Celera1196,224,705 - 196,225,356UniSTS
Cytogenetic Map1q42UniSTS
Cdkn1c  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21198,655,568 - 198,656,314 (+)MAPPERmRatBN7.2
Rnor_6.01216,661,242 - 216,661,987NCBIRnor6.0
Rnor_5.01223,521,273 - 223,522,018UniSTSRnor5.0
RGSC_v3.41203,835,390 - 203,836,135UniSTSRGSC3.4
Celera1196,223,988 - 196,224,733UniSTS
Cytogenetic Map1q42UniSTS
Cdkn1c  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21198,657,094 - 198,657,287 (+)MAPPERmRatBN7.2
Rnor_6.01216,662,768 - 216,662,960NCBIRnor6.0
Rnor_5.01223,522,799 - 223,522,991UniSTSRnor5.0
Rnor_5.01223,522,799 - 223,523,211UniSTSRnor5.0
Celera1196,225,514 - 196,225,706UniSTS
Cytogenetic Map1q42UniSTS
Cdkn1c  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21198,656,284 - 198,656,938 (+)MAPPERmRatBN7.2
Rnor_6.01216,661,958 - 216,662,611NCBIRnor6.0
Rnor_5.01223,521,989 - 223,522,642UniSTSRnor5.0
RGSC_v3.41203,836,106 - 203,836,759UniSTSRGSC3.4
Celera1196,224,704 - 196,225,357UniSTS
Cytogenetic Map1q42UniSTS
Cdkn1c  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21198,656,296 - 198,657,287 (+)MAPPERmRatBN7.2
Rnor_6.01216,661,970 - 216,662,960NCBIRnor6.0
Rnor_5.01223,522,001 - 223,522,991UniSTSRnor5.0
Rnor_5.01223,522,001 - 223,523,211UniSTSRnor5.0
Celera1196,224,716 - 196,225,706UniSTS
Cytogenetic Map1q42UniSTS
Cdkn1c  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21198,656,919 - 198,657,523 (+)MAPPERmRatBN7.2
Rnor_6.01216,662,593 - 216,663,196NCBIRnor6.0
Rnor_5.01223,522,624 - 223,523,447UniSTSRnor5.0
RGSC_v3.41203,836,741 - 203,837,319UniSTSRGSC3.4
Celera1196,225,339 - 196,225,942UniSTS
Cytogenetic Map1q42UniSTS
Cdkn1c  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21198,656,232 - 198,656,943 (+)MAPPERmRatBN7.2
Rnor_6.01216,661,906 - 216,662,616NCBIRnor6.0
Rnor_5.01223,521,937 - 223,522,647UniSTSRnor5.0
Celera1196,224,652 - 196,225,362UniSTS
Cytogenetic Map1q42UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High 2
Medium 24 26 18 18 4 4 61 35 32 11 4
Low 3 17 31 23 19 23 4 7 13 9 4
Below cutoff

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001033757 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001033758 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_182735 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008760076 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008760077 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008760078 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008760079 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC112093 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AJ488291 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY351678 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY351679 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY576608 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY586728 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC098646 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CB775146 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CF110214 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH473953 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JACYVU010000044 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSRNOT00000077409   ⟹   ENSRNOP00000074510
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1198,655,407 - 198,658,048 (-)Ensembl
Rnor_6.0 Ensembl1216,661,080 - 216,663,721 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000078944   ⟹   ENSRNOP00000073616
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1198,655,407 - 198,658,047 (-)Ensembl
Rnor_6.0 Ensembl1216,661,080 - 216,663,720 (-)Ensembl
RefSeq Acc Id: NM_001033757   ⟹   NP_001028929
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21198,655,394 - 198,658,047 (-)NCBI
Rnor_6.01216,661,067 - 216,663,720 (-)NCBI
Rnor_5.01223,521,098 - 223,524,053 (-)NCBI
RGSC_v3.41203,835,215 - 203,837,844 (-)RGD
Celera1196,223,813 - 196,226,466 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001033758   ⟹   NP_001028930
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21198,655,394 - 198,658,047 (-)NCBI
Rnor_6.01216,661,067 - 216,663,720 (-)NCBI
Rnor_5.01223,521,098 - 223,524,053 (-)NCBI
RGSC_v3.41203,835,215 - 203,837,844 (-)RGD
Celera1196,223,813 - 196,226,466 (-)NCBI
Sequence:
RefSeq Acc Id: NM_182735   ⟹   NP_877399
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21198,655,394 - 198,658,048 (-)NCBI
Rnor_6.01216,661,067 - 216,663,721 (-)NCBI
Rnor_5.01223,521,098 - 223,524,053 (-)NCBI
RGSC_v3.41203,835,215 - 203,837,844 (-)RGD
Celera1196,223,813 - 196,226,467 (-)RGD
Sequence:
RefSeq Acc Id: XM_008760076   ⟹   XP_008758298
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21198,655,394 - 198,658,095 (-)NCBI
Rnor_6.01216,661,067 - 216,663,787 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008760077   ⟹   XP_008758299
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21198,655,394 - 198,658,097 (-)NCBI
Rnor_6.01216,661,067 - 216,663,791 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008760078   ⟹   XP_008758300
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21198,655,394 - 198,658,094 (-)NCBI
Rnor_6.01216,661,067 - 216,663,785 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008760079   ⟹   XP_008758301
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21198,655,394 - 198,658,094 (-)NCBI
Rnor_6.01216,661,067 - 216,663,786 (-)NCBI
Sequence:
Reference Protein Sequences
RefSeq Acc Id: NP_877399   ⟸   NM_182735
- Peptide Label: isoform 2
- UniProtKB: Q69DC0 (UniProtKB/TrEMBL),   E9PTV7 (UniProtKB/TrEMBL),   Q6KF59 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001028929   ⟸   NM_001033757
- Peptide Label: isoform 1
- UniProtKB: Q69DC1 (UniProtKB/TrEMBL),   A0A0G2K5Z5 (UniProtKB/TrEMBL),   Q6KF59 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001028930   ⟸   NM_001033758
- Peptide Label: isoform 2
- UniProtKB: Q69DC0 (UniProtKB/TrEMBL),   E9PTV7 (UniProtKB/TrEMBL),   Q6KF59 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_008758299   ⟸   XM_008760077
- Peptide Label: isoform X1
- UniProtKB: Q69DC1 (UniProtKB/TrEMBL),   A0A0G2K5Z5 (UniProtKB/TrEMBL),   Q6KF59 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_008758298   ⟸   XM_008760076
- Peptide Label: isoform X1
- UniProtKB: Q69DC1 (UniProtKB/TrEMBL),   A0A0G2K5Z5 (UniProtKB/TrEMBL),   Q6KF59 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_008758301   ⟸   XM_008760079
- Peptide Label: isoform X2
- UniProtKB: A6HYB5 (UniProtKB/TrEMBL),   Q6KF59 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_008758300   ⟸   XM_008760078
- Peptide Label: isoform X2
- UniProtKB: A6HYB5 (UniProtKB/TrEMBL),   Q6KF59 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000074510   ⟸   ENSRNOT00000077409
RefSeq Acc Id: ENSRNOP00000073616   ⟸   ENSRNOT00000078944
Protein Domains
Cyclin-dependent kinase inhibitor

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q69DC1-F1-model_v2 AlphaFold Q69DC1 1-355 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13690572
Promoter ID:EPDNEW_R1097
Type:single initiation site
Name:Cdkn1c_1
Description:cyclin-dependent kinase inhibitor 1C
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01216,663,728 - 216,663,788EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:727892 AgrOrtholog
BioCyc Gene G2FUF-56870 BioCyc
Ensembl Genes ENSRNOG00000059500 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000077409 ENTREZGENE
  ENSRNOT00000077409.2 UniProtKB/TrEMBL
  ENSRNOT00000078944 ENTREZGENE
  ENSRNOT00000078944.2 UniProtKB/TrEMBL
Gene3D-CATH 4.10.365.10 UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7109418 IMAGE-MGC_LOAD
InterPro CDI UniProtKB/TrEMBL
  CDI_dom_sf UniProtKB/TrEMBL
KEGG Report rno:246060 UniProtKB/TrEMBL
MGC_CLONE MGC:112585 IMAGE-MGC_LOAD
NCBI Gene 246060 ENTREZGENE
PANTHER CYCLIN-DEPENDENT KINASE INHIBITOR 1 UniProtKB/TrEMBL
  PTHR10265:SF44 UniProtKB/TrEMBL
Pfam CDI UniProtKB/TrEMBL
PhenoGen Cdkn1c PhenoGen
RatGTEx ENSRNOG00000059500 RatGTEx
UniProt A0A0G2K5Z5 ENTREZGENE, UniProtKB/TrEMBL
  A6HYB4_RAT UniProtKB/TrEMBL
  A6HYB5 ENTREZGENE, UniProtKB/TrEMBL
  A6HYB6_RAT UniProtKB/TrEMBL
  E9PTV7 ENTREZGENE
  Q69DC0 ENTREZGENE, UniProtKB/TrEMBL
  Q69DC1 ENTREZGENE, UniProtKB/TrEMBL
  Q6KF59 ENTREZGENE, UniProtKB/TrEMBL
UniProt Secondary E9PTV7 UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2009-11-05 Cdkn1c  cyclin-dependent kinase inhibitor 1C  Cdkn1c  cyclin-dependent kinase inhibitor 1C (P57)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-07-08 Cdkn1c  cyclin-dependent kinase inhibitor 1C (P57)    cyclin-dependent kinase inhibitor 1C, p57  Name updated 1299863 APPROVED
2005-02-23 Cdkn1c  cyclin-dependent kinase inhibitor 1C, p57  Cdkn1c_predicted  cyclin-dependent kinase inhibitor 1C (P57) (predicted)  Data merged from RGD:1311494 737654 APPROVED
2005-01-12 Cdkn1c_predicted  cyclin-dependent kinase inhibitor 1C (P57) (predicted)      Symbol and Name status set to provisional 70820 PROVISIONAL