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Gene: Cd81 (Cd81 molecule) Rattus norvegicus
Symbol: Cd81
Name: Cd81 molecule
Description: Predicted to have cholesterol binding activity; signaling receptor binding activity; and virus receptor activity. Involved in regulation of cell population proliferation; regulation of growth; and response to wounding. Localizes to apical plasma membrane and integral component of membrane. Human ortholog(s) of this gene implicated in common variable immunodeficiency. Orthologous to human CD81 (CD81 molecule); PARTICIPATES IN B cell receptor signaling pathway; hepatitis C pathway; malaria pathway; INTERACTS WITH 17alpha-ethynylestradiol; 2,6-di-tert-butyl-4-methylphenol; 2,6-dinitrotoluene.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 26 kDa cell surface protein TAPA-1; CD 81 antigen; CD81 antigen; CD81 antigen (target of antiproliferative antibody 1); Tapa1; target of the antiproliferative antibody 1
Homo sapiens (human) : CD81 (CD81 molecule)  HGNC  Alliance
Mus musculus (house mouse) : Cd81 (CD81 antigen)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Cd81 (CD81 molecule)
Pan paniscus (bonobo/pygmy chimpanzee) : CD81 (CD81 molecule)
Canis lupus familiaris (dog) : CD81 (CD81 molecule)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Cd81 (CD81 molecule)
Sus scrofa (pig) : CD81 (CD81 molecule)
Chlorocebus sabaeus (African green monkey) : CD81 (CD81 molecule)
Heterocephalus glaber (naked mole-rat) : Cd81 (CD81 molecule)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.01216,237,663 - 216,253,460 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1216,237,697 - 216,253,311 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01223,099,328 - 223,114,942 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41203,327,287 - 203,342,901 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11203,480,739 - 203,496,354 (+)NCBI
Celera1195,804,757 - 195,820,558 (+)NCBICelera
Cytogenetic Map1q41-q42NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Candidate Gene Status
Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
More on Cd81
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 2315
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2020-07-28
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.