Predicted to enable fibroblast growth factor receptor binding activity and growth factor activity. Involved in response to ethanol. Predicted to be active in cytoplasm and extracellular space. Biomarker of alcoholic hepatitis. Orthologous to human FGF19 (fibroblast growth factor 19); PARTICIPATES IN fibroblast growth factor signaling pathway; melanoma pathway; mitogen activated protein kinase signaling pathway; INTERACTS WITH ammonium chloride; bis(2-ethylhexyl) phthalate; bisphenol A.
[Ethinyl Estradiol co-treated with Metformin] results in decreased expression of FGF15 mRNA and alisol B 23-acetate promotes the reaction [Ethinyl Estradiol results in increased expression of FGF15 mRNA]
fexaramine inhibits the reaction [Aflatoxin B1 results in decreased expression of FGF15 mRNA] and fexaramine inhibits the reaction [Aflatoxin B1 results in decreased expression of FGF15 protein]
pyrazolanthrone inhibits the reaction [FGF19 protein results in decreased expression of CYP17A1 mRNA] and pyrazolanthrone inhibits the reaction [FGF19 protein results in decreased expression of PON1 mRNA]
[[Chenodeoxycholic Acid results in increased activity of NR1H4 protein] which binds to FGF19 promoter] which results in increased expression of FGF19 mRNA and [Chenodeoxycholic Acid results in increased activity of NR1H4 protein] which binds to FGF19 promoter
[[Cholic Acid results in increased activity of NR1H4 protein] which binds to FGF19 promoter] which results in increased expression of FGF19 mRNA and [Cholic Acid results in increased activity of NR1H4 protein] which binds to FGF19 promoter
[[Deoxycholic Acid results in increased activity of NR1H4 protein] which binds to FGF19 promoter] which results in increased expression of FGF19 mRNA and [Deoxycholic Acid results in increased activity of NR1H4 protein] which binds to FGF19 promoter
[Dexamethasone co-treated with Ibuprofen] results in decreased expression of FGF15 mRNA and [Dexamethasone co-treated with Ibuprofen] results in decreased expression of FGF15 protein
[NOG protein co-treated with entinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of FGF19 mRNA
fexaramine inhibits the reaction [Aflatoxin B1 results in decreased expression of FGF15 mRNA] and fexaramine inhibits the reaction [Aflatoxin B1 results in decreased expression of FGF15 protein]
Z-guggulsterone reverses the reaction [Dihydroartemisinin inhibits the reaction [ethanol decreases expression of FGF19 protein in liver and intestine]]
[[GW 4064 results in increased activity of NR1H4 protein] which binds to FGF19 promoter] which results in increased expression of FGF19 mRNA and [GW 4064 results in increased activity of NR1H4 protein] which binds to FGF19 promoter
[Dexamethasone co-treated with Ibuprofen] results in decreased expression of FGF15 mRNA and [Dexamethasone co-treated with Ibuprofen] results in decreased expression of FGF15 protein
[NOG protein co-treated with Panobinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of FGF19 mRNA
[caffeic acid phenethyl ester co-treated with Dietary Fats] results in decreased expression of FGF15 mRNA and GW 4064 inhibits the reaction [[caffeic acid phenethyl ester co-treated with Dietary Fats] results in decreased expression of FGF15 mRNA]
[Dietary Fats co-treated with Streptozocin] results in increased expression of FGF15 mRNA and [Dietary Fats co-treated with Streptozocin] results in increased expression of FGF15 protein