FGF19 (fibroblast growth factor 19) - Rat Genome Database

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Gene: FGF19 (fibroblast growth factor 19) Sus scrofa
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Symbol: FGF19
Name: fibroblast growth factor 19
RGD ID: 14052950
Description: ENCODES a protein that exhibits fibroblast growth factor receptor binding (inferred); growth factor activity (inferred); INVOLVED IN bile acid and bile salt transport (ortholog); fibroblast growth factor receptor signaling pathway (ortholog); heart development (ortholog); PARTICIPATES IN fibroblast growth factor signaling pathway; ASSOCIATED WITH alcoholic hepatitis (ortholog); colitis (ortholog); Hepatic Insufficiency (ortholog); FOUND IN extracellular region (inferred)
Type: protein-coding
RefSeq Status: MODEL
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl23,583,027 - 3,587,825 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.123,583,027 - 3,586,985 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.222,060,776 - 2,065,925 (+)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Molecular Pathway Annotations     Click to see Annotation Detail View
References

Genomics

Comparative Map Data
FGF19
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl23,583,027 - 3,587,825 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.123,583,027 - 3,586,985 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.222,060,776 - 2,065,925 (+)NCBISscrofa10.2Sscrofa10.2susScr3
FGF19
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1169,698,238 - 69,704,022 (-)EnsemblGRCh38hg38GRCh38
GRCh381169,698,238 - 69,704,022 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371169,513,006 - 69,518,790 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361169,222,187 - 69,228,287 (-)NCBINCBI36hg18NCBI36
Build 341169,222,187 - 69,228,287NCBI
Celera1166,810,044 - 66,816,141 (-)NCBI
Cytogenetic Map11q13.3NCBI
HuRef1165,805,191 - 65,811,289 (-)NCBIHuRef
CHM1_11169,396,002 - 69,402,103 (-)NCBICHM1_1
Fgf15
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm397144,450,269 - 144,454,690 (+)NCBIGRCm39mm39
GRCm39 Ensembl7144,450,268 - 144,454,690 (+)Ensembl
GRCm387144,896,532 - 144,900,953 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl7144,896,531 - 144,900,953 (+)EnsemblGRCm38mm10GRCm38
MGSCv377152,082,437 - 152,086,858 (+)NCBIGRCm37mm9NCBIm37
MGSCv367144,705,922 - 144,710,343 (+)NCBImm8
Celera7144,661,763 - 144,666,199 (+)NCBICelera
Cytogenetic Map7F5NCBI
Fgf19
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21200,056,656 - 200,059,944 (+)NCBImRatBN7.2
mRatBN7.2 Ensembl1200,056,644 - 200,060,287 (+)Ensembl
Rnor_6.01218,058,405 - 218,061,693 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1218,058,405 - 218,061,693 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01224,927,791 - 224,931,079 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41205,324,890 - 205,328,178 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11205,478,342 - 205,481,631 (+)NCBI
Celera1197,614,723 - 197,618,011 (+)NCBICelera
Cytogenetic Map1q42NCBI
Fgf19
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542216,415,648 - 16,420,515 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495542216,415,880 - 16,419,528 (+)NCBIChiLan1.0ChiLan1.0
FGF19
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11168,085,306 - 68,090,028 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1168,085,306 - 68,090,028 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01164,794,157 - 64,800,512 (-)NCBIMhudiblu_PPA_v0panPan3
FGF19
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11848,464,931 - 48,469,967 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1848,464,928 - 48,469,782 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1847,074,788 - 47,079,858 (+)NCBI
ROS_Cfam_1.01849,142,011 - 49,147,073 (+)NCBI
UMICH_Zoey_3.11848,586,353 - 48,593,734 (+)NCBI
UNSW_CanFamBas_1.01848,174,953 - 48,180,024 (+)NCBI
UU_Cfam_GSD_1.01848,920,964 - 48,926,046 (+)NCBI
Fgf19
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244049474,485,587 - 4,491,068 (+)NCBI
SpeTri2.0NW_004936599923,943 - 932,428 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
FGF19
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.114,852,289 - 4,860,139 (+)NCBIChlSab1.1chlSab2
ChlSab1.1 Ensembl14,854,363 - 4,859,102 (+)EnsemblChlSab1.1chlSab2
Vero_WHO_p1.0NW_023666038102,128,324 - 102,135,894 (+)NCBIVero_WHO_p1.0
Fgf19
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462476717,434,501 - 17,439,351 (+)NCBIHetGla_female_1.0hetGla2


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system
High
Medium
Low
Below cutoff 1

Sequence


Reference Sequences
RefSeq Acc Id: ENSSSCT00000058728   ⟹   ENSSSCP00000051161
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl23,583,027 - 3,587,825 (+)Ensembl
RefSeq Acc Id: XM_003122420   ⟹   XP_003122468
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.123,583,027 - 3,586,985 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_003122468 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: XP_003122468   ⟸   XM_003122420
- UniProtKB: F1RY79 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSSSCP00000051161   ⟸   ENSSSCT00000058728


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000012871 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCG00070001632 UniProtKB/TrEMBL
Ensembl Protein ENSSSCP00000051161 ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCP00070002507 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000058728 ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCT00070003043 UniProtKB/TrEMBL
InterPro FGF15/19/21 UniProtKB/TrEMBL
  FGF15/FGF19 UniProtKB/TrEMBL
  Fibroblast_GF_fam UniProtKB/TrEMBL
  IL1/FGF UniProtKB/TrEMBL
KEGG Report ssc:100518950 UniProtKB/TrEMBL
NCBI Gene FGF19 ENTREZGENE
PANTHER PTHR11486 UniProtKB/TrEMBL
  PTHR11486:SF74 UniProtKB/TrEMBL
Pfam FGF UniProtKB/TrEMBL
PIRSF FGF-19_FGF-21 UniProtKB/TrEMBL
PRINTS HBGFFGF UniProtKB/TrEMBL
PROSITE HBGF_FGF UniProtKB/TrEMBL
SMART FGF UniProtKB/TrEMBL
Superfamily-SCOP SSF50353 UniProtKB/TrEMBL
UniProt A0A287B3V5_PIG UniProtKB/TrEMBL
  A0A4X1SJA6_PIG UniProtKB/TrEMBL
  F1RY79 ENTREZGENE
VGNC ID VGNC:88108 ENTREZGENE