GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Fgf19 | increases expression | EXP | | 6480464 | CTD | Chenodeoxycholic Acid results in increased expression of FGF15 mRNA; Chenodeoxycholic Acid results in increased expression of FGF19 protein | PMID:20835427 PMID:29222744 | Fgf19 | multiple interactions | EXP | | 6480464 | CTD | [Chenodeoxycholic Acid results in increased expression of FGF19 protein] which results in decreased expression of CYP7A1 protein | PMID:20835427 | Fgf19 | increases expression | ISO | FGF19 (Homo sapiens) | 6480464 | CTD | Chenodeoxycholic Acid results in increased expression of FGF19 mRNA | PMID:16269825 PMID:17696253 PMID:25055961 PMID:27174168 | Fgf19 | increases expression | ISO | Fgf15 (Mus musculus) | 6480464 | CTD | Chenodeoxycholic Acid results in increased expression of FGF15 mRNA | PMID:25582706 | Fgf19 | multiple interactions | ISO | FGF19 (Homo sapiens) | 6480464 | CTD | [[Chenodeoxycholic Acid results in increased activity of NR1H4 protein] which binds to FGF19 promoter] which results in increased expression of FGF19 mRNA; [Chenodeoxycholic Acid results in increased activity of NR1H4 protein] which binds to FGF19 promoter | PMID:22561792 | |
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