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Gene: Unc93b1 (unc-93 homolog B1, TLR signaling regulator) Rattus norvegicus
Symbol: Unc93b1
Name: unc-93 homolog B1, TLR signaling regulator
Description: Predicted to have Toll-like receptor binding activity. Predicted to be involved in several processes, including antigen processing and presentation of exogenous peptide antigen via MHC class II; positive regulation of cytokine secretion; and toll-like receptor signaling pathway. Predicted to localize to cytoplasmic vesicle; endoplasmic reticulum; and lysosome. Human ortholog(s) of this gene implicated in brain disease. Orthologous to human UNC93B1 (unc-93 homolog B1, TLR signaling regulator); PARTICIPATES IN Toll-like receptor signaling pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; acetamide; bisphenol A.
Type: protein-coding
Also known as: LOC361689; unc-93 homolog B; unc-93 homolog B (C. elegans); unc-93 homolog B1; unc-93 homolog B1 (C. elegans); Unc93b
Homo sapiens (human) : UNC93B1 (unc-93 homolog B1, TLR signaling regulator)  HGNC  Alliance
Mus musculus (house mouse) : Unc93b1 (unc-93 homolog B1, TLR signaling regulator)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Unc93b1 (unc-93 homolog B1, TLR signaling regulator)
Pan paniscus (bonobo/pygmy chimpanzee) : UNC93B1 (unc-93 homolog B1, TLR signaling regulator)
Canis lupus familiaris (dog) : UNC93B1 (unc-93 homolog B1, TLR signaling regulator)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Unc93b1 (unc-93 homolog B1, TLR signaling regulator)
Sus scrofa (pig) : UNC93B1 (unc-93 homolog B1, TLR signaling regulator)
Chlorocebus sabaeus (African green monkey) : UNC93B1 (unc-93 homolog B1, TLR signaling regulator)
Heterocephalus glaber (naked mole-rat) : Unc93b1 (unc-93 homolog B1, TLR signaling regulator)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.01219,172,987 - 219,183,941 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1219,144,205 - 219,183,963 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01226,043,713 - 226,054,652 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41206,460,302 - 206,471,239 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11206,613,779 - 206,624,694 (+)NCBI
Celera1198,720,875 - 198,731,812 (+)NCBICelera
Cytogenetic Map1q43NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
More on Unc93b1
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1311984
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2020-06-09
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.