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Gene: Clcf1 (cardiotrophin-like cytokine factor 1) Rattus norvegicus
Symbol: Clcf1
Name: cardiotrophin-like cytokine factor 1
RGD ID: 1303171
Description: Predicted to have ciliary neurotrophic factor receptor binding activity and cytokine activity. Predicted to be involved in several processes, including positive regulation of B cell activation; positive regulation of astrocyte differentiation; and positive regulation of tyrosine phosphorylation of STAT protein. Predicted to localize to CNTFR-CLCF1 complex and CRLF-CLCF1 complex. Human ortholog(s) of this gene implicated in cold-induced sweating syndrome 2. Orthologous to human CLCF1 (cardiotrophin like cytokine factor 1); PARTICIPATES IN cytokine mediated signaling pathway; Jak-Stat signaling pathway; INTERACTS WITH (+)-schisandrin B; 2,4-dinitrotoluene; 2,6-dinitrotoluene.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: B-cell stimulating factor 3; Bsf3; cardiotrophin-like cytokine; Clc; LOC365395; MGC112574; NNT-1; novel neurotrophin-1
Homo sapiens (human) : CLCF1 (cardiotrophin like cytokine factor 1)  HGNC  Alliance
Mus musculus (house mouse) : Clcf1 (cardiotrophin-like cytokine factor 1)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Clcf1 (cardiotrophin like cytokine factor 1)
Pan paniscus (bonobo/pygmy chimpanzee) : CLCF1 (cardiotrophin like cytokine factor 1)
Canis lupus familiaris (dog) : CLCF1 (cardiotrophin like cytokine factor 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Clcf1 (cardiotrophin like cytokine factor 1)
Sus scrofa (pig) : CLCF1 (cardiotrophin like cytokine factor 1)
Chlorocebus sabaeus (African green monkey) : CLCF1 (cardiotrophin like cytokine factor 1)
Heterocephalus glaber (naked mole-rat) : Clcf1 (cardiotrophin like cytokine factor 1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.01219,468,866 - 219,472,445 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1219,468,675 - 219,472,654 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01226,338,540 - 226,342,119 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41206,802,745 - 206,806,332 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11206,956,450 - 206,958,891 (+)NCBI
Celera1199,058,438 - 199,062,024 (+)NCBICelera
Cytogenetic Map1q43NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
More on Clcf1
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1303171
Created: 2004-12-03
Species: Rattus norvegicus
Last Modified: 2020-11-24
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.