Gene: Pc (pyruvate carboxylase) Rattus norvegicus
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Symbol: Pc
Name: pyruvate carboxylase
Description: Exhibits ATP binding activity, biotin binding activity, and pyruvate carboxylase activity; involved in carboxylic acid metabolic process, gluconeogenesis, and positive regulation of phospholipid biosynthetic process; localizes to the mitochondrion; orthologous to human PC (pyruvate carboxylase); PARTICIPATES IN gluconeogenesis pathway; pyruvate metabolic pathway; alanine metabolic pathway; INTERACTS WITH 1-naphthyl isothiocyanate; 17alpha-ethynylestradiol; 2,2,2-tetramine.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: PCB; Pcx; pyruvate carboxylase, mitochondrial; pyruvic carboxylase
Orthologs:
Homo sapiens (human) : PC (pyruvate carboxylase)  HGNC  Alliance
Mus musculus (house mouse) : Pcx (pyruvate carboxylase)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Pc (pyruvate carboxylase)
Pan paniscus (bonobo/pygmy chimpanzee) : PC (pyruvate carboxylase)
Canis lupus familiaris (dog) : PC (pyruvate carboxylase)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Pc (pyruvate carboxylase)
Sus scrofa (pig) : PC (pyruvate carboxylase)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01219,759,157 - 219,859,854 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01226,626,831 - 226,726,350 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41207,112,853 - 207,212,737 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11207,266,305 - 207,366,189 (+)NCBI
Celera1199,343,224 - 199,439,273 (+)NCBICelera
Cytogenetic Map1q43NCBI
RH 3.4 Map11554.4RGD
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Pc
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 3262
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.