Gene: Kcnk4 (potassium two pore domain channel subfamily K member 4) Rattus norvegicus
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Symbol: Kcnk4
Name: potassium two pore domain channel subfamily K member 4
Description: ENCODES a protein that exhibits mechanosensitived potassium channel activity; potassium channel activity; temperature-gated cation channel activity; INVOLVED IN cellular response to alkaline pH; cellular response to fatty acid; cellular response to temperature stimulus; ASSOCIATED WITH visual epilepsy (ortholog); FOUND IN integral component of plasma membrane; potassium channel complex (ortholog); INTERACTS WITH aflatoxin B1; ammonium chloride; bis(2-ethylhexyl) phthalate
AGR Description: Exhibits mechanosensitived potassium channel activity and temperature-gated cation channel activity; involved in several processes, including cellular response to alkaline pH, cellular response to fatty acid, and cellular response to temperature stimulus; localizes to the integral component of plasma membrane; orthologous to human KCNK4 (potassium two pore domain channel subfamily K member 4).
Merged Description: Exhibits mechanosensitived potassium channel activity and temperature-gated cation channel activity; involved in several processes, including cellular response to alkaline pH, cellular response to fatty acid, and cellular response to temperature stimulus; localizes to the integral component of plasma membrane; orthologous to human KCNK4 (potassium two pore domain channel subfamily K member 4); INTERACTS WITH aflatoxin B1; ammonium chloride; bis(2-ethylhexyl) phthalate.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: KT4.1; potassium channel subfamily K member 4; potassium channel, subfamily K, member 4; potassium channel, two pore domain subfamily K, member 4; potassium inwardly-rectifying channel subfamily K member 4; potassium inwardly-rectifying channel, subfamily K, member 4; TRAAK
Orthologs:
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01222,182,997 - 222,192,139 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01229,173,229 - 229,182,887 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41209,602,228 - 209,608,521 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11209,760,657 - 209,766,951 (-)NCBI
Celera1201,652,646 - 201,658,974 (-)NCBICelera
Cytogenetic Map1q43NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 5.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Kcnk4
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 621449
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2019-04-12
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.