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Gene: Map3k11 (mitogen-activated protein kinase kinase kinase 11) Rattus norvegicus
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Symbol: Map3k11
Name: mitogen-activated protein kinase kinase kinase 11
Description: Exhibits ATP binding activity; JUN kinase kinase kinase activity; and enzyme binding activity. Involved in cell death; cellular protein modification process; and positive regulation of neuron apoptotic process. Predicted to localize to the centrosome and microtubule. Orthologous to human MAP3K11 (mitogen-activated protein kinase kinase kinase 11); PARTICIPATES IN c-Jun N-terminal kinases MAPK signaling pathway; p38 MAPK signaling pathway; Reelin signaling pathway; INTERACTS WITH 2,4-dinitrotoluene; 2,6-dinitrotoluene; 6-propyl-2-thiouracil.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: mixed lineage kinase 3; Mlk-3; Mlk3; RHOE
Orthologs:
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01221,043,119 - 221,056,420 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01227,978,441 - 227,991,742 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41208,312,955 - 208,326,289 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11208,466,407 - 208,479,739 (+)NCBI
Celera1200,511,102 - 200,524,400 (+)NCBICelera
Cytogenetic Map1q43NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
 
More on Map3k11
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1359261
Created: 2005-07-29
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.