Alc34 QTL Report (Rattus norvegicus) - Rat Genome Database

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QTL: Alc34 (Alcohol consumption QTL 34) Rattus norvegicus

Symbol: Alc34
Name: Alcohol consumption QTL 34
RGD ID: 8693661
Trait: drinking behavior trait   (VT:0001422)    
Measurement Type: calculated ethanol drink intake rate   (CMO:0001615)    
LOD Score: 2.2
P Value: 0.611
Variance: Not Available
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_6.01227,509,470 - 249,252,048RGD_MAPPER_PIPELINERnor6.0
Rnor_5.01234,574,271 - 256,490,738RGD_MAPPER_PIPELINERnor5.0
RGSC_v3.41213,847,769 - 234,642,714RGD_MAPPER_PIPELINERGSC3.4
Cross Type: Not Available
Strains Crossed: BXH/Ipcv HXB/Ipcv 

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Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
Experimental Data Annotations     Click to see Annotation Detail View

Clinical Measurement

Measurement Method
scale  (IDA)

Vertebrate Trait

Rat Strain
BXH/Ipcv  (IEA)
HXB/Ipcv  (IEA)


References - curated
# Reference Title Reference Citation
1. Is the Alcohol Deprivation Effect Genetically Mediated? Studies with HXB/BXH Recombinant Inbred Rat Strains. Vanderlinden LA, etal., Alcohol Clin Exp Res. 2014 Jun 24. doi: 10.1111/acer.12471.


Markers in Region
The following Markers overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolExpected SizeChrStartStopSpeciesMatch
Position Markers

Flank 1: (rs107452597)
Rat AssemblyChrPosition (strand)Source
Rnor_6.01227,509,470 - 227,509,470RGD
Rnor_5.01234,574,271 - 234,574,271RGD
RGSC_v3.41213,847,769 - 213,847,769RGD
Celera1205,462,252 - 205,462,252RGD
Flank 2: (rs64209861)
Rat AssemblyChrPosition (strand)Source
Rnor_6.01249,252,048 - 249,252,048RGD
Rnor_5.01256,490,738 - 256,490,738RGD
RGSC_v3.41234,642,714 - 234,642,714RGD
Celera1225,759,203 - 225,759,203RGD

Additional Information

RGD Curation Notes
Note Type Note Reference
qtl_general measurement method: rats were given 10% EtOH for 1 week, then for 7 weeks they were given 2-bottle choice of water and EtOH followed by 2 week period of only water (alcohol deprivation); then 2 weeks of 2-bottle choice of water and EtOH followed by second 2 weeks of alcohol deprivation then 2 weeks of 2-bottle choice of water and EtOH followed by third 2 weeks of alcohol deprivation and 1 week of 2-bottle choice of water and EtOH 8663441
qtl_general water and alcohol consumption were measured by weight 8663441
qtl_general alcohol deprivation effect (ADE) was calculated as the amount of alcohol consumed (g/kg) during 24 hrs after deprivation minus average daily amount consumed in the week before deprivation period 8663441
qtl_general this QTL correlates to week 11 post-ADE alcohol consumption 8663441
qtl_general software used: ANOVA 8663441
qtl_general number of animals used: 70-100 days old males from HXB/BXH RI strains and the parental BN-Lx/CubPrin, SHR/OlaIpcvPrin 8663441
qtl_general spans 234.9-256.4 Mb 8663441