(-)-citrinin multiple interactions EXP 6480464 Citrinin inhibits the reaction [SLC22A6 protein results in increased uptake of ochratoxin A] CTD PMID:10336520 1,1-dichloroethene decreases expression ISO RGD:619573 6480464 vinylidene chloride results in decreased expression of SLC22A6 mRNA CTD PMID:26682919 1,2-dimethylhydrazine decreases expression ISO RGD:619573 6480464 1, 2-Dimethylhydrazine results in decreased expression of SLC22A6 mRNA CTD PMID:22206623 1-naphthyl isothiocyanate decreases expression EXP 6480464 1-Naphthylisothiocyanate results in decreased expression of SLC22A6 mRNA CTD PMID:30723492 2,2',4,4',5,5'-hexachlorobiphenyl multiple interactions ISO RGD:619573 6480464 [2 more ... CTD PMID:25510870 2,2',5,5'-tetrachlorobiphenyl multiple interactions ISO RGD:619573 6480464 [2 more ... CTD PMID:25510870 2,2,2-tetramine multiple interactions EXP 6480464 Trientine inhibits the reaction [Streptozocin results in decreased expression of SLC22A6 protein] CTD PMID:19634143 2,3,7,8-tetrachlorodibenzodioxine affects expression EXP 6480464 Tetrachlorodibenzodioxin affects the expression of SLC22A6 mRNA CTD PMID:22298810 2,3,7,8-tetrachlorodibenzodioxine decreases expression EXP 6480464 Tetrachlorodibenzodioxin results in decreased expression of SLC22A6 mRNA CTD PMID:32109520 2,3,7,8-Tetrachlorodibenzofuran decreases expression EXP 6480464 2 more ... CTD PMID:32109520 2,4-D increases uptake EXP 6480464 SLC22A6 protein results in increased uptake of 2, 4-Dichlorophenoxyacetic Acid CTD PMID:16857889 2,4-D increases uptake ISO RGD:619572 6480464 SLC22A6 protein results in increased uptake of 2, 4-Dichlorophenoxyacetic Acid CTD PMID:16857889 , PMID:17255469 2,4-D multiple interactions ISO RGD:619572 6480464 p-Aminohippuric Acid inhibits the reaction [SLC22A6 protein results in increased uptake of 2, 4-Dichlorophenoxyacetic Acid] CTD PMID:17255469 3-chloropropane-1,2-diol increases expression EXP 6480464 alpha-Chlorohydrin results in increased expression of SLC22A6 mRNA CTD PMID:28522335 4,4'-diisothiocyano-trans-stilbene-2,2'-disulfonic acid multiple interactions ISO RGD:619572 6480464 4 more ... CTD PMID:12472777 4,4'-sulfonyldiphenol multiple interactions ISO RGD:619572 6480464 bis(4-hydroxyphenyl)sulfone inhibits the reaction [SLC22A6 protein results in increased uptake of p-Aminohippuric Acid] CTD PMID:27989701 5-azaorotic acid multiple interactions EXP 6480464 [Oxonic Acid co-treated with Uric Acid] results in decreased expression of SLC22A6 protein CTD PMID:19605544 5-azaorotic acid multiple interactions ISO RGD:619573 6480464 [Oxonic Acid analog co-treated with Hypoxanthine] results in decreased expression of SLC22A6 mRNA more ... CTD PMID:34687833 5-formyltetrahydrofolic acid multiple interactions EXP 6480464 Leucovorin inhibits the reaction [Methotrexate results in decreased expression of SLC22A6 protein] CTD PMID:16925582 5-formyltetrahydrofolic acid increases uptake ISO RGD:619572 6480464 SLC22A6 protein results in increased uptake of Leucovorin CTD PMID:16098483 6-carboxyfluorescein multiple interactions ISO RGD:619572 6480464 2-amino-1-methyl-6-phenylimidazo(4 more ... CTD PMID:28629854 6-carboxyfluorescein increases import ISO RGD:619572 6480464 SLC22A6 protein results in increased import of 6-carboxyfluorescein CTD PMID:28629854 6-propyl-2-thiouracil decreases expression EXP 6480464 Propylthiouracil results in decreased expression of SLC22A6 mRNA CTD PMID:24780913 6-propyl-2-thiouracil increases expression EXP 6480464 Propylthiouracil results in increased expression of SLC22A6 mRNA CTD PMID:25825206 7,9-dihydro-1H-purine-2,6,8(3H)-trione multiple interactions ISO RGD:619572 6480464 4 more ... CTD PMID:12472777 7,9-dihydro-1H-purine-2,6,8(3H)-trione multiple interactions EXP 6480464 [Oxonic Acid co-treated with Uric Acid] results in decreased expression of SLC22A6 protein CTD PMID:19605544 7,9-dihydro-1H-purine-2,6,8(3H)-trione affects secretion ISO RGD:619573 6480464 SLC22A6 protein affects the secretion of Uric Acid CTD PMID:19605544 7,9-dihydro-1H-purine-2,6,8(3H)-trione increases uptake ISO RGD:619572 6480464 SLC22A6 protein results in increased uptake of Uric Acid CTD PMID:12472777 9-[2-(phosphonomethoxy)ethyl]guanine multiple interactions ISO RGD:619572 6480464 9-((2-phosphonylmethoxy)ethyl)guanine analog inhibits the reaction [SLC22A6 protein results in increased uptake of p-Aminohippuric Acid] more ... CTD PMID:23856525 9-[2-(phosphonomethoxy)ethyl]guanine increases response to substance ISO RGD:619572 6480464 SLC22A6 protein results in increased susceptibility to 9-((2-phosphonylmethoxy)ethyl)guanine, SLC22A6 protein results in increased susceptibility to 9-((2-phosphonylmethoxy)ethyl)guanine analog CTD PMID:23856525 acetylsalicylic acid decreases activity ISO RGD:619572 6480464 Aspirin results in decreased activity of SLC22A6 protein CTD PMID:12388633 adefovir increases uptake EXP 6480464 SLC22A6 protein results in increased uptake of adefovir CTD PMID:16857889 adefovir multiple interactions EXP 6480464 [adefovir co-treated with Probenecid co-treated with Cromolyn Sodium] affects the expression of SLC22A6 protein more ... CTD PMID:35114312 adefovir decreases expression EXP 6480464 adefovir results in decreased expression of SLC22A6 protein CTD PMID:35114312 adefovir affects response to substance ISO RGD:619572 6480464 SLC22A6 protein affects the susceptibility to adefovir CTD PMID:21244849 adefovir multiple interactions ISO RGD:619572 6480464 adefovir inhibits the reaction [SLC22A6 protein results in increased uptake of p-Aminohippuric Acid] more ... CTD PMID:21244849 more ... adefovir increases response to substance ISO RGD:619572 6480464 SLC22A6 protein results in increased susceptibility to adefovir CTD PMID:23856525 adefovir increases uptake ISO RGD:619572 6480464 SLC22A6 protein results in increased uptake of adefovir CTD PMID:16857889 adipic acid multiple interactions ISO RGD:619572 6480464 adipic acid inhibits the reaction [SLC22A6 protein results in increased susceptibility to [mercuric oxide co-treated with Acetylcysteine]], adipic acid inhibits the reaction [SLC22A6 protein results in increased transport of 2-amino-3-(2-amino-2-carboxyethylsulfanyl-mercuricsulfanyl)-propionic acid analog] CTD PMID:12606766 , PMID:15284288 aflatoxin B1 decreases methylation ISO RGD:619572 6480464 Aflatoxin B1 results in decreased methylation of SLC22A6 5' UTR CTD PMID:30157460 allopurinol multiple interactions ISO RGD:619573 6480464 Allopurinol inhibits the reaction [[Oxonic Acid analog co-treated with Hypoxanthine] results in decreased expression of SLC22A6 mRNA] more ... CTD PMID:21909718 more ... allopurinol multiple interactions EXP 6480464 Allopurinol inhibits the reaction [Fructose results in decreased expression of SLC22A6 mRNA], Allopurinol inhibits the reaction [Fructose results in decreased expression of SLC22A6 protein] CTD PMID:19605544 amitriptyline multiple interactions ISO RGD:619572 6480464 Amitriptyline inhibits the reaction [SLC22A6 protein results in increased uptake of p-Aminohippuric Acid] CTD PMID:21561794 ammonium chloride affects expression EXP 6480464 Ammonium Chloride affects the expression of SLC22A6 mRNA CTD PMID:16483693 angelicin increases expression ISO RGD:619573 6480464 angelicin results in increased expression of SLC22A6 protein CTD PMID:22173200 aristolochic acid A multiple interactions ISO RGD:619572 6480464 [wedelolactone results in decreased activity of SLC22A6 protein] which results in increased susceptibility to and results in increased activity of aristolochic acid I more ... CTD PMID:19643159 , PMID:32159797 aristolochic acids increases uptake ISO RGD:619572 6480464 SLC22A6 results in increased uptake of Aristolochic Acids CTD PMID:19643159 aristolochic acids multiple interactions ISO RGD:619572 6480464 [SLC22A6 results in increased uptake of Aristolochic Acids] which results in increased chemical synthesis of 7-(deoxyadenosin-N(6)-yl)aristolactam I more ... CTD PMID:19643159 aristolochic acids decreases expression EXP 6480464 Aristolochic Acids results in decreased expression of SLC22A6 mRNA CTD PMID:19717638 , PMID:21167265 aurantio-obtusin decreases activity ISO RGD:619572 6480464 aurantio-obtusin results in decreased activity of SLC22A6 protein CTD PMID:29045746 bacitracin decreases expression EXP 6480464 Bacitracin results in decreased expression of SLC22A6 mRNA CTD PMID:18289764 baicalein decreases activity ISO RGD:619572 6480464 baicalein results in decreased activity of SLC22A6 protein CTD PMID:32159797 bendroflumethiazide decreases activity ISO RGD:619573 6480464 Bendroflumethiazide results in decreased activity of SLC22A6 protein CTD PMID:18216144 bendroflumethiazide increases secretion ISO RGD:619573 6480464 SLC22A6 protein results in increased secretion of Bendroflumethiazide CTD PMID:18216144 benzbromarone multiple interactions ISO RGD:619572 6480464 Benzbromarone inhibits the reaction [SLC22A6 protein affects the transport of Uric Acid] CTD PMID:12472777 benzo[a]pyrene increases methylation ISO RGD:619572 6480464 Benzo(a)pyrene results in increased methylation of SLC22A6 3' UTR CTD PMID:27901495 benzo[a]pyrene affects methylation ISO RGD:619572 6480464 Benzo(a)pyrene affects the methylation of SLC22A6 promoter CTD PMID:27901495 benzo[a]pyrene decreases activity ISO RGD:619572 6480464 Benzo(a)pyrene results in decreased activity of SLC22A6 protein CTD PMID:31830554 benzylpenicillin multiple interactions ISO RGD:619572 6480464 Penicillin G inhibits the reaction [SLC22A6 protein results in increased uptake of p-Aminohippuric Acid] CTD PMID:11602689 bisphenol A increases expression EXP 6480464 bisphenol A results in increased expression of SLC22A6 mRNA CTD PMID:17010207 bisphenol A multiple interactions ISO RGD:619572 6480464 bisphenol A promotes the reaction [SLC22A6 protein results in increased uptake of p-Aminohippuric Acid] CTD PMID:27989701 bisphenol A decreases expression EXP 6480464 bisphenol A results in decreased expression of SLC22A6 mRNA CTD PMID:25181051 more ... bisphenol F multiple interactions ISO RGD:619572 6480464 bisphenol F promotes the reaction [SLC22A6 protein results in increased uptake of p-Aminohippuric Acid] CTD PMID:27989701 bromosulfophthalein multiple interactions ISO RGD:619572 6480464 Sulfobromophthalein inhibits the reaction [SLC22A6 protein results in increased uptake of p-Aminohippuric Acid] CTD PMID:11602689 cadmium dichloride increases expression ISO RGD:619572 6480464 Cadmium Chloride results in increased expression of SLC22A6 mRNA CTD PMID:12160620 cadmium dichloride decreases expression EXP 6480464 Cadmium Chloride results in decreased expression of SLC22A6 mRNA, Cadmium Chloride results in decreased expression of SLC22A6 protein CTD PMID:25588984 cefaclor multiple interactions ISO RGD:619572 6480464 Cefaclor inhibits the reaction [SLC22A6 protein results in increased uptake of p-Aminohippuric Acid] CTD PMID:16098483 cefaloridine increases import EXP 6480464 SLC22A6 protein results in increased import of Cephaloridine CTD PMID:10594788 cefaloridine multiple interactions ISO RGD:619572 6480464 Cephaloridine inhibits the reaction [SLC22A6 protein results in increased uptake of p-Aminohippuric Acid] CTD PMID:16098483 cefaloridine increases uptake ISO RGD:619572 6480464 SLC22A6 protein results in increased uptake of Cephaloridine CTD PMID:16098483 cefdinir multiple interactions ISO RGD:619572 6480464 cefdinir inhibits the reaction [SLC22A6 protein results in increased uptake of p-Aminohippuric Acid] CTD PMID:16098483 cefdinir increases uptake ISO RGD:619572 6480464 SLC22A6 protein results in increased uptake of cefdinir CTD PMID:16098483 cefoselis sulfate multiple interactions ISO RGD:619572 6480464 cefoselis inhibits the reaction [SLC22A6 protein results in increased uptake of p-Aminohippuric Acid] CTD PMID:16098483 cefotiam multiple interactions ISO RGD:619572 6480464 Cefotiam inhibits the reaction [SLC22A6 protein results in increased uptake of p-Aminohippuric Acid] CTD PMID:16098483 ceftibuten increases uptake ISO RGD:619572 6480464 SLC22A6 protein results in increased uptake of ceftibuten CTD PMID:16098483 ceftibuten multiple interactions ISO RGD:619572 6480464 ceftibuten inhibits the reaction [SLC22A6 protein results in increased uptake of p-Aminohippuric Acid] CTD PMID:16098483 ceftizoxime multiple interactions ISO RGD:619572 6480464 Ceftizoxime inhibits the reaction [SLC22A6 protein results in increased uptake of p-Aminohippuric Acid] CTD PMID:16098483 ceftizoxime increases uptake ISO RGD:619572 6480464 SLC22A6 protein results in increased uptake of Ceftizoxime CTD PMID:16098483 chlorpyrifos-methyl multiple interactions ISO RGD:619572 6480464 chlorpyrifos-methyl inhibits the reaction [SLC22A6 protein results in increased uptake of p-Aminohippuric Acid] CTD PMID:21561794 chrysophanol decreases activity ISO RGD:619572 6480464 chrysophanic acid results in decreased activity of SLC22A6 protein CTD PMID:29045746 cidofovir anhydrous increases response to substance ISO RGD:619572 6480464 SLC22A6 protein results in increased susceptibility to Cidofovir CTD PMID:23856525 cidofovir anhydrous multiple interactions ISO RGD:619572 6480464 SLC22A6 protein results in increased uptake of and results in increased susceptibility to Cidofovir CTD PMID:25448811 cidofovir anhydrous increases import ISO RGD:619572 6480464 SLC22A6 protein results in increased import of Cidofovir CTD PMID:29738843 ciguatoxin CTX1B affects expression ISO RGD:619573 6480464 Ciguatoxins affects the expression of SLC22A6 mRNA CTD PMID:18353800 cimetidine multiple interactions ISO RGD:619572 6480464 1-Methyl-4-phenylpyridinium inhibits the reaction [SLC22A6 protein results in increased uptake of Cimetidine] more ... CTD PMID:15496291 cimetidine increases uptake ISO RGD:619572 6480464 SLC22A6 protein results in increased uptake of Cimetidine CTD PMID:15496291 more ... cisplatin decreases expression EXP 6480464 Cisplatin results in decreased expression of SLC22A6 mRNA, Cisplatin results in decreased expression of SLC22A6 protein CTD PMID:22992436 cisplatin multiple interactions EXP 6480464 JBP 485 inhibits the reaction [Cisplatin results in decreased expression of SLC22A6 mRNA] CTD PMID:22992436 clothianidin decreases activity ISO RGD:619572 6480464 clothianidin results in decreased activity of SLC22A6 protein CTD PMID:31364238 cyazofamid multiple interactions ISO RGD:619572 6480464 cyazofamid inhibits the reaction [SLC22A6 protein results in increased uptake of p-Aminohippuric Acid] CTD PMID:32003934 D-gluconic acid multiple interactions ISO RGD:619572 6480464 gluconic acid inhibits the reaction [SLC22A6 protein affects the transport of Uric Acid] CTD PMID:12472777 diazepam multiple interactions ISO RGD:619572 6480464 Diazepam inhibits the reaction [SLC22A6 protein results in increased uptake of p-Aminohippuric Acid] CTD PMID:21561794 diclofenac decreases activity ISO RGD:619572 6480464 Diclofenac results in decreased activity of SLC22A6 protein CTD PMID:12388633 diethyl hydrogen phosphate decreases expression EXP 6480464 diethyl phosphate results in decreased expression of SLC22A6 mRNA CTD PMID:31835022 disodium cromoglycate multiple interactions EXP 6480464 [adefovir co-treated with Probenecid co-treated with Cromolyn Sodium] affects the expression of SLC22A6 protein, Cromolyn Sodium inhibits the reaction [Purines analog results in decreased expression of SLC22A6 protein] CTD PMID:35114312 , PMID:36464070 doxycycline multiple interactions ISO RGD:619572 6480464 Doxycycline inhibits the reaction [SLC22A6 protein results in increased uptake of Anions] CTD PMID:11855680 emodin decreases activity ISO RGD:619572 6480464 Emodin results in decreased activity of SLC22A6 protein CTD PMID:29045746 estrone 3-sulfate increases uptake ISO RGD:619572 6480464 SLC22A6 protein results in increased uptake of estrone sulfate CTD PMID:16098483 fenitrothion multiple interactions ISO RGD:619572 6480464 Fenitrothion inhibits the reaction [SLC22A6 protein results in increased uptake of p-Aminohippuric Acid] CTD PMID:21561794 fluorescein (lactone form) multiple interactions ISO RGD:619572 6480464 Fluorescein inhibits the reaction [SLC22A6 protein results in increased uptake of p-Aminohippuric Acid] CTD PMID:11602689 folic acid decreases expression EXP 6480464 Folic Acid results in decreased expression of SLC22A6 mRNA, Folic Acid results in decreased expression of SLC22A6 protein CTD PMID:19552531 fructose decreases expression EXP 6480464 Fructose results in decreased expression of SLC22A6 mRNA, Fructose results in decreased expression of SLC22A6 protein CTD PMID:19605544 fructose multiple interactions EXP 6480464 Allopurinol inhibits the reaction [Fructose results in decreased expression of SLC22A6 mRNA] more ... CTD PMID:19605544 furan increases methylation EXP 6480464 furan results in increased methylation of SLC22A6 gene CTD PMID:22079235 furosemide increases expression EXP 6480464 Furosemide results in increased expression of SLC22A6 protein CTD PMID:12897087 furosemide increases secretion ISO RGD:619573 6480464 SLC22A6 protein results in increased secretion of Furosemide CTD PMID:18216144 furosemide decreases activity ISO RGD:619573 6480464 Furosemide results in decreased activity of SLC22A6 protein CTD PMID:18216144 genistein increases expression EXP 6480464 Genistein results in increased expression of SLC22A6 mRNA CTD PMID:17010207 genistein increases uptake ISO RGD:619572 6480464 SLC22A6 protein results in increased uptake of Genistein analog CTD PMID:21244849 genistein decreases expression EXP 6480464 Genistein results in decreased expression of SLC22A6 mRNA CTD PMID:21782745 gentamycin decreases expression EXP 6480464 Gentamicins results in decreased expression of SLC22A6 mRNA, Gentamicins results in decreased expression of SLC22A6 protein CTD PMID:19967075 , PMID:23707770 gentamycin multiple interactions EXP 6480464 JBP 485 inhibits the reaction [Gentamicins results in decreased expression of SLC22A6 mRNA], JBP 485 inhibits the reaction [Gentamicins results in decreased expression of SLC22A6 protein] CTD PMID:23707770 glutaric acid multiple interactions ISO RGD:619572 6480464 glutaric acid inhibits the reaction [SLC22A6 protein results in increased transport of 2-amino-3-(2-amino-2-carboxyethylsulfanyl-mercuricsulfanyl)-propionic acid analog] more ... CTD PMID:15284288 more ... glutaric acid increases import ISO RGD:619572 6480464 SLC22A6 protein results in increased import of glutaric acid CTD PMID:28629854 glutaric acid increases activity ISO RGD:619572 6480464 glutaric acid results in increased activity of SLC22A6 protein CTD PMID:28629854 glutathione multiple interactions ISO RGD:619572 6480464 SLC22A6 protein results in increased susceptibility to [mercuric oxide co-treated with Glutathione] CTD PMID:12606766 glycidol decreases expression EXP 6480464 glycidol results in decreased expression of SLC22A6 mRNA CTD PMID:24915197 GW 4064 increases expression ISO RGD:619573 6480464 GW 4064 results in increased expression of SLC22A6 mRNA CTD PMID:26655953 herbicide multiple interactions EXP 6480464 [perfluoro-n-nonanoic acid co-treated with [Phytochemicals co-treated with Environmental Pollutants co-treated with Food Preservatives co-treated with Plasticizers co-treated with Sunscreening Agents co-treated with Insecticides co-treated with Fungicides, Industrial co-treated with Herbicides]] results in increased expression of SLC22A6 protein CTD PMID:25588985 hydrochlorothiazide increases expression EXP 6480464 Hydrochlorothiazide results in increased expression of SLC22A6 protein CTD PMID:12897087 hypoxanthine multiple interactions ISO RGD:619573 6480464 [Oxonic Acid analog co-treated with Hypoxanthine] results in decreased expression of SLC22A6 mRNA more ... CTD PMID:34687833 ibuprofen decreases activity ISO RGD:619572 6480464 Ibuprofen results in decreased activity of SLC22A6 protein CTD PMID:12388633 ibuprofen increases uptake ISO RGD:619572 6480464 SLC22A6 protein results in increased uptake of Ibuprofen CTD PMID:12388633 imperatorin decreases expression ISO RGD:619573 6480464 imperatorin results in decreased expression of SLC22A6 protein CTD PMID:22173200 indometacin decreases activity ISO RGD:619572 6480464 Indomethacin results in decreased activity of SLC22A6 protein CTD PMID:12388633 indometacin increases uptake ISO RGD:619572 6480464 SLC22A6 protein results in increased uptake of Indomethacin CTD PMID:12388633 isoimperatorin decreases expression ISO RGD:619573 6480464 isoimperatorin results in decreased expression of SLC22A6 protein CTD PMID:22173200 ketoprofen decreases activity ISO RGD:619572 6480464 Ketoprofen results in decreased activity of SLC22A6 protein CTD PMID:12388633 ketoprofen increases uptake ISO RGD:619572 6480464 SLC22A6 protein results in increased uptake of Ketoprofen CTD PMID:12388633 linoleic acid decreases activity ISO RGD:619572 6480464 Linoleic Acid results in decreased activity of SLC22A6 protein CTD PMID:29045746 luteolin decreases activity ISO RGD:619572 6480464 Luteolin results in decreased activity of SLC22A6 protein CTD PMID:32159797 malathion multiple interactions ISO RGD:619572 6480464 Malathion inhibits the reaction [SLC22A6 protein results in increased uptake of p-Aminohippuric Acid] CTD PMID:21561794 mefenamic acid decreases activity ISO RGD:619572 6480464 Mefenamic Acid results in decreased activity of SLC22A6 protein CTD PMID:12388633 Mercuric oxide multiple interactions ISO RGD:619572 6480464 adipic acid inhibits the reaction [SLC22A6 protein results in increased susceptibility to [mercuric oxide co-treated with Acetylcysteine]] more ... CTD PMID:12606766 mercury atom multiple interactions ISO RGD:619572 6480464 SLC22A6 gene SNP affects the susceptibility to and affects the abundance of Mercury, SLC22A6 protein results in increased transport of [Acetylcysteine co-treated with Mercury] CTD PMID:15908511 , PMID:23052037 mercury atom affects response to substance ISO RGD:619572 6480464 SLC22A6 gene SNP affects the susceptibility to Mercury CTD PMID:32946573 mercury dichloride decreases expression EXP 6480464 Mercuric Chloride results in decreased expression of SLC22A6 mRNA CTD PMID:16507785 , PMID:28536007 mercury dichloride increases expression EXP 6480464 Mercuric Chloride results in increased expression of SLC22A6 protein CTD PMID:30031051 mercury(0) multiple interactions ISO RGD:619572 6480464 SLC22A6 gene SNP affects the susceptibility to and affects the abundance of Mercury, SLC22A6 protein results in increased transport of [Acetylcysteine co-treated with Mercury] CTD PMID:15908511 , PMID:23052037 mercury(0) affects response to substance ISO RGD:619572 6480464 SLC22A6 gene SNP affects the susceptibility to Mercury CTD PMID:32946573 methotrexate decreases expression EXP 6480464 Methotrexate results in decreased expression of SLC22A6 protein CTD PMID:16925582 methotrexate multiple interactions ISO RGD:619572 6480464 resveratrol inhibits the reaction [SLC22A6 protein results in increased uptake of Methotrexate], rhein metabolite inhibits the reaction [SLC22A6 protein results in increased uptake of Methotrexate] CTD PMID:27377006 , PMID:28890383 methotrexate increases response to substance ISO RGD:619572 6480464 SLC22A6 protein results in increased susceptibility to Methotrexate CTD PMID:27377006 methotrexate increases uptake ISO RGD:619572 6480464 SLC22A6 protein results in increased uptake of Methotrexate CTD PMID:16098483 more ... methotrexate multiple interactions EXP 6480464 Leucovorin inhibits the reaction [Methotrexate results in decreased expression of SLC22A6 protein] CTD PMID:16925582 methoxsalen decreases expression ISO RGD:619573 6480464 Methoxsalen results in decreased expression of SLC22A6 protein CTD PMID:22173200 methylmercury chloride increases expression EXP 6480464 methylmercuric chloride results in increased expression of SLC22A6 mRNA CTD PMID:28536007 mianserin multiple interactions ISO RGD:619572 6480464 Mianserin inhibits the reaction [SLC22A6 protein results in increased uptake of p-Aminohippuric Acid] CTD PMID:21561794 minocycline multiple interactions ISO RGD:619572 6480464 Minocycline inhibits the reaction [SLC22A6 protein results in increased uptake of Anions] CTD PMID:11855680 N-acetyl-L-cysteine multiple interactions ISO RGD:619572 6480464 adipic acid inhibits the reaction [SLC22A6 protein results in increased susceptibility to [mercuric oxide co-treated with Acetylcysteine]] more ... CTD PMID:12606766 , PMID:15908511 N-methyl-4-phenylpyridinium multiple interactions ISO RGD:619572 6480464 1-Methyl-4-phenylpyridinium inhibits the reaction [SLC22A6 protein results in increased uptake of Cimetidine] CTD PMID:15496291 N1'-[2-[[5-[(dimethylamino)methyl]-2-furanyl]methylthio]ethyl]-N1-methyl-2-nitroethene-1,1-diamine increases uptake ISO RGD:619572 6480464 SLC22A6 protein results in increased uptake of Ranitidine CTD PMID:16006492 naproxen decreases activity ISO RGD:619572 6480464 Naproxen results in decreased activity of SLC22A6 protein CTD PMID:12388633 Nonylphenol increases expression EXP 6480464 nonylphenol results in increased expression of SLC22A6 mRNA CTD PMID:17010207 Obtusifolin decreases activity ISO RGD:619572 6480464 obtusifolin results in decreased activity of SLC22A6 protein CTD PMID:29045746 ochratoxin A multiple interactions EXP 6480464 Citrinin inhibits the reaction [SLC22A6 protein results in increased uptake of ochratoxin A] more ... CTD PMID:10336520 , PMID:15068970 ochratoxin A decreases expression EXP 6480464 ochratoxin A results in decreased expression of SLC22A6 mRNA, ochratoxin A results in decreased expression of SLC22A6 protein CTD PMID:12700408 more ... ochratoxin A increases uptake ISO RGD:619572 6480464 SLC22A6 protein results in increased uptake of ochratoxin A CTD PMID:16098483 , PMID:17353191 ochratoxin A multiple interactions ISO RGD:619572 6480464 Chlorides promotes the reaction [SLC22A6 protein results in increased uptake of ochratoxin A] CTD PMID:17353191 ochratoxin A increases expression EXP 6480464 ochratoxin A results in increased expression of SLC22A6 protein CTD PMID:19538982 ochratoxin A increases uptake EXP 6480464 SLC22A6 protein results in increased uptake of ochratoxin A CTD PMID:10336520 octanoic acid multiple interactions EXP 6480464 octanoic acid inhibits the reaction [SLC22A6 protein results in increased uptake of ochratoxin A] CTD PMID:10336520 oroxylin A decreases activity ISO RGD:619572 6480464 5, 7-dihydroxy-6-methoxy-2-phenylchromen-4-one results in decreased activity of SLC22A6 protein CTD PMID:32305507 oroxylin A multiple interactions ISO RGD:619572 6480464 5, 7-dihydroxy-6-methoxy-2-phenylchromen-4-one inhibits the reaction [SLC22A6 protein results in increased uptake of p-Aminohippuric Acid] CTD PMID:32305507 oxytetracycline multiple interactions ISO RGD:619572 6480464 Oxytetracycline inhibits the reaction [SLC22A6 protein results in increased uptake of Anions] CTD PMID:11855680 p-aminohippuric acid affects transport ISO RGD:619572 6480464 SLC22A6 protein affects the transport of p-Aminohippuric Acid CTD PMID:15496291 p-aminohippuric acid multiple interactions ISO RGD:619572 6480464 5 more ... CTD PMID:11602689 more ... p-aminohippuric acid increases uptake ISO RGD:619572 6480464 SLC22A6 protein results in increased uptake of p-Aminohippuric Acid, SLC22A6 results in increased uptake of p-Aminohippuric Acid CTD PMID:11602689 more ... p-aminohippuric acid increases import ISO RGD:619572 6480464 SLC22A6 protein results in increased import of p-Aminohippuric Acid CTD PMID:28629854 p-aminohippuric acid increases export ISO RGD:619572 6480464 SLC22A6 results in increased export of p-Aminohippuric Acid CTD PMID:19643159 p-aminohippuric acid increases secretion ISO RGD:619572 6480464 SLC22A6 protein results in increased secretion of p-Aminohippuric Acid CTD PMID:11602689 p-aminohippuric acid affects transport ISO RGD:619573 6480464 SLC22A6 protein affects the transport of p-Aminohippuric Acid CTD PMID:18216144 p-aminohippuric acid increases import EXP 6480464 SLC22A6 protein results in increased import of p-Aminohippuric Acid CTD PMID:19915082 p-aminohippuric acid multiple interactions EXP 6480464 p-Aminohippuric Acid inhibits the reaction [SLC22A6 protein results in increased uptake of ochratoxin A] more ... CTD PMID:10336520 , PMID:19915082 paracetamol decreases activity ISO RGD:619572 6480464 Acetaminophen results in decreased activity of SLC22A6 protein CTD PMID:12388633 paracetamol decreases expression ISO RGD:619572 6480464 Acetaminophen results in decreased expression of SLC22A6 mRNA CTD PMID:22230336 paraquat affects expression EXP 6480464 Paraquat affects the expression of SLC22A6 mRNA CTD PMID:15206577 paraquat increases expression EXP 6480464 Paraquat results in increased expression of SLC22A6 mRNA CTD PMID:18198484 PCB138 multiple interactions ISO RGD:619573 6480464 [2 more ... CTD PMID:25510870 perfluoroheptanoic acid multiple interactions EXP 6480464 perfluoro-n-heptanoic acid inhibits the reaction [SLC22A6 protein results in increased import of p-Aminohippuric Acid] CTD PMID:19915082 perfluoroheptanoic acid increases import EXP 6480464 SLC22A6 protein results in increased import of perfluoro-n-heptanoic acid CTD PMID:19915082 perfluorohexanoic acid multiple interactions EXP 6480464 perfluorohexanoic acid inhibits the reaction [SLC22A6 protein results in increased import of p-Aminohippuric Acid] CTD PMID:19915082 perfluorononanoic acid multiple interactions EXP 6480464 [perfluoro-n-nonanoic acid co-treated with [Phytochemicals co-treated with Environmental Pollutants co-treated with Food Preservatives co-treated with Plasticizers co-treated with Sunscreening Agents co-treated with Insecticides co-treated with Fungicides, Industrial co-treated with Herbicides]] results in increased expression of SLC22A6 protein CTD PMID:25588985 perfluorooctanoic acid multiple interactions EXP 6480464 perfluorooctanoic acid inhibits the reaction [SLC22A6 protein results in increased import of p-Aminohippuric Acid] CTD PMID:19915082 perfluorooctanoic acid increases import EXP 6480464 SLC22A6 protein results in increased import of perfluorooctanoic acid CTD PMID:19915082 phenacetin decreases activity ISO RGD:619572 6480464 Phenacetin results in decreased activity of SLC22A6 protein CTD PMID:12388633 PhIP decreases activity ISO RGD:619572 6480464 2-amino-1-methyl-6-phenylimidazo(4, 5-b)pyridine results in decreased activity of SLC22A6 protein CTD PMID:28629854 PhIP multiple interactions ISO RGD:619572 6480464 2-amino-1-methyl-6-phenylimidazo(4, 5-b)pyridine inhibits the reaction [SLC22A6 protein results in increased import of 6-carboxyfluorescein] CTD PMID:28629854 pirinixic acid increases expression EXP 6480464 pirinixic acid results in increased expression of SLC22A6 mRNA CTD PMID:12832660 piroxicam decreases activity ISO RGD:619572 6480464 Piroxicam results in decreased activity of SLC22A6 protein CTD PMID:12388633 piroxicam multiple interactions EXP 6480464 Piroxicam inhibits the reaction [SLC22A6 protein results in increased uptake of ochratoxin A] CTD PMID:10336520 Potassium 2,6-dihydroxytriazinecarboxylate decreases expression ISO RGD:619573 6480464 potassium oxonate results in decreased expression of SLC22A6 mRNA, potassium oxonate results in decreased expression of SLC22A6 protein CTD PMID:21909718 more ... Potassium 2,6-dihydroxytriazinecarboxylate multiple interactions ISO RGD:619573 6480464 Allopurinol inhibits the reaction [potassium oxonate results in decreased expression of SLC22A6 protein] more ... CTD PMID:21909718 more ... pregnenolone 16alpha-carbonitrile decreases expression ISO RGD:619573 6480464 Pregnenolone Carbonitrile results in decreased expression of SLC22A6 mRNA CTD PMID:22698814 probenecid multiple interactions ISO RGD:619572 6480464 Probenecid inhibits the reaction [[SLC22A6 results in increased uptake of Aristolochic Acids] which results in increased chemical synthesis of 7-(deoxyadenosin-N(6)-yl)aristolactam I] more ... CTD PMID:11602689 more ... probenecid decreases activity ISO RGD:619572 6480464 Probenecid results in decreased activity of SLC22A6 protein CTD PMID:28629854 more ... probenecid multiple interactions ISO RGD:619573 6480464 Probenecid inhibits the reaction [potassium oxonate results in decreased expression of SLC22A6 mRNA], Probenecid inhibits the reaction [potassium oxonate results in decreased expression of SLC22A6 protein] CTD PMID:22865646 , PMID:22967667 probenecid multiple interactions EXP 6480464 [adefovir co-treated with Probenecid co-treated with Cromolyn Sodium] affects the expression of SLC22A6 protein more ... CTD PMID:10336520 , PMID:35114312 prostaglandin E2 decreases expression EXP 6480464 Dinoprostone results in decreased expression of SLC22A6 protein CTD PMID:19605544 purines decreases expression EXP 6480464 Purines analog results in decreased expression of SLC22A6 protein CTD PMID:36464070 purines multiple interactions EXP 6480464 Cromolyn Sodium inhibits the reaction [Purines analog results in decreased expression of SLC22A6 protein], Valsartan inhibits the reaction [Purines analog results in decreased expression of SLC22A6 protein] CTD PMID:36464070 pyrazine-2-carboxylic acid multiple interactions ISO RGD:619572 6480464 pyrazinoic acid inhibits the reaction [SLC22A6 protein affects the transport of Uric Acid] CTD PMID:12472777 quercetin affects expression EXP 6480464 Quercetin affects the expression of SLC22A6 protein CTD PMID:24958931 quercetin decreases activity ISO RGD:619572 6480464 Quercetin results in decreased activity of SLC22A6 protein CTD PMID:32159797 quercetin multiple interactions ISO RGD:619573 6480464 Quercetin inhibits the reaction [potassium oxonate results in decreased expression of SLC22A6 mRNA], Quercetin inhibits the reaction [potassium oxonate results in decreased expression of SLC22A6 protein] CTD PMID:21909718 quercetin multiple interactions EXP 6480464 Quercetin inhibits the reaction [Fructose results in decreased expression of SLC22A6 mRNA], Quercetin inhibits the reaction [Fructose results in decreased expression of SLC22A6 protein] CTD PMID:19605544 quercetin multiple interactions ISO RGD:619572 6480464 Quercetin inhibits the reaction [SLC22A6 protein results in increased susceptibility to 9-((2-phosphonylmethoxy)ethyl)guanine analog] more ... CTD PMID:19605544 , PMID:23856525 quercetin 3-sulfate multiple interactions ISO RGD:619572 6480464 quercetin 3'-sulfate inhibits the reaction [SLC22A6 protein affects the susceptibility to adefovir], quercetin 3'-sulfate inhibits the reaction [SLC22A6 protein results in increased uptake of p-Aminohippuric Acid] CTD PMID:21244849 quercetin 3-sulfate increases uptake ISO RGD:619572 6480464 SLC22A6 protein results in increased uptake of quercetin 3'-sulfate CTD PMID:21244849 ranitidine increases uptake ISO RGD:619572 6480464 SLC22A6 protein results in increased uptake of Ranitidine CTD PMID:16006492 resveratrol affects expression EXP 6480464 resveratrol affects the expression of SLC22A6 protein CTD PMID:24958931 resveratrol multiple interactions ISO RGD:619572 6480464 [Plant Extracts co-treated with Resveratrol] results in decreased expression of SLC22A6 mRNA more ... CTD PMID:23557933 , PMID:27377006 resveratrol multiple interactions ISO RGD:619573 6480464 resveratrol inhibits the reaction [potassium oxonate results in decreased expression of SLC22A6 protein] CTD PMID:22865646 Rhein multiple interactions ISO RGD:619572 6480464 rhein inhibits the reaction [SLC22A6 protein results in increased uptake of p-Aminohippuric Acid] more ... CTD PMID:28890383 riddelliine decreases expression EXP 6480464 riddelliine results in decreased expression of SLC22A6 mRNA CTD PMID:18047722 rutin multiple interactions EXP 6480464 Rutin inhibits the reaction [Fructose results in decreased expression of SLC22A6 mRNA], Rutin inhibits the reaction [Fructose results in decreased expression of SLC22A6 protein] CTD PMID:19605544 salicylates multiple interactions ISO RGD:619572 6480464 Salicylates inhibits the reaction [SLC22A6 protein affects the transport of Uric Acid] CTD PMID:12472777 salicylic acid decreases activity ISO RGD:619572 6480464 Salicylic Acid results in decreased activity of SLC22A6 protein CTD PMID:12388633 salicylic acid increases uptake ISO RGD:619572 6480464 SLC22A6 protein results in increased uptake of Salicylic Acid CTD PMID:12388633 sodium arsenite affects methylation ISO RGD:619572 6480464 sodium arsenite affects the methylation of SLC22A6 gene CTD PMID:28589171 sodium dichromate increases expression EXP 6480464 sodium bichromate results in increased expression of SLC22A6 mRNA CTD PMID:12325037 sodium hydrogencarbonate decreases expression EXP 6480464 Sodium Bicarbonate results in decreased expression of SLC22A6 mRNA CTD PMID:29126803 streptozocin multiple interactions EXP 6480464 Trientine inhibits the reaction [Streptozocin results in decreased expression of SLC22A6 protein] CTD PMID:19634143 streptozocin decreases expression EXP 6480464 Streptozocin results in decreased expression of SLC22A6 protein CTD PMID:19634143 sulindac decreases activity ISO RGD:619572 6480464 Sulindac results in decreased activity of SLC22A6 protein CTD PMID:12388633 taurocholic acid multiple interactions ISO RGD:619572 6480464 Taurocholic Acid inhibits the reaction [SLC22A6 protein results in increased uptake of p-Aminohippuric Acid] CTD PMID:11602689 tenofovir disoproxil fumarate multiple interactions ISO RGD:619572 6480464 Probenecid inhibits the reaction [SLC22A6 protein results in increased susceptibility to Tenofovir] more ... CTD PMID:23856525 , PMID:25448811 tenofovir disoproxil fumarate increases import ISO RGD:619572 6480464 SLC22A6 protein results in increased import of Tenofovir CTD PMID:29738843 tenofovir disoproxil fumarate increases response to substance ISO RGD:619572 6480464 SLC22A6 protein results in increased susceptibility to Tenofovir CTD PMID:23856525 testosterone increases expression ISO RGD:619573 6480464 Testosterone results in increased expression of SLC22A6 protein CTD PMID:23389457 tetracycline increases export ISO RGD:619572 6480464 SLC22A6 protein results in increased export of Tetracycline CTD PMID:11855680 tetracycline multiple interactions ISO RGD:619572 6480464 Tetracycline inhibits the reaction [SLC22A6 protein results in increased uptake of Anions] CTD PMID:11855680 tetracycline increases uptake ISO RGD:619572 6480464 SLC22A6 protein results in increased uptake of Tetracycline CTD PMID:11855680 trans-piceid multiple interactions ISO RGD:619573 6480464 polydatin inhibits the reaction [potassium oxonate results in decreased expression of SLC22A6 protein] CTD PMID:22865646 triazolam multiple interactions ISO RGD:619572 6480464 Triazolam inhibits the reaction [SLC22A6 protein results in increased uptake of p-Aminohippuric Acid] CTD PMID:21561794 valsartan multiple interactions EXP 6480464 [adefovir co-treated with Probenecid co-treated with Valsartan] affects the expression of SLC22A6 protein more ... CTD PMID:35114312 , PMID:36464070 vancomycin increases expression ISO RGD:619573 6480464 Vancomycin results in increased expression of SLC22A6 mRNA CTD PMID:18930951 vancomycin multiple interactions EXP 6480464 JBP 485 inhibits the reaction [Vancomycin results in decreased expression of SLC22A6 mRNA], JBP 485 inhibits the reaction [Vancomycin results in decreased expression of SLC22A6 protein] CTD PMID:29964132 vancomycin decreases expression EXP 6480464 Vancomycin results in decreased expression of SLC22A6 mRNA, Vancomycin results in decreased expression of SLC22A6 protein CTD PMID:29964132 wedelolactone multiple interactions ISO RGD:619572 6480464 [wedelolactone results in decreased activity of SLC22A6 protein] which results in increased susceptibility to and results in increased activity of aristolochic acid I CTD PMID:32159797 wedelolactone decreases activity ISO RGD:619572 6480464 wedelolactone results in decreased activity of SLC22A6 protein CTD PMID:32159797 wogonin multiple interactions ISO RGD:619572 6480464 [wogonin results in decreased activity of SLC22A6 protein] which results in increased susceptibility to and results in increased activity of aristolochic acid I CTD PMID:32159797 wogonin decreases activity ISO RGD:619572 6480464 wogonin results in decreased activity of SLC22A6 protein CTD PMID:32159797
