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Gene: Slc22a6 (solute carrier family 22 member 6) Rattus norvegicus
Symbol: Slc22a6
Name: solute carrier family 22 member 6
Description: Exhibits anion transmembrane transporter activity; chloride ion binding activity; and identical protein binding activity. Involved in response to methotrexate and sodium-independent organic anion transport. Localizes to the caveola and protein-containing complex. Orthologous to human SLC22A6 (solute carrier family 22 member 6); PARTICIPATES IN multispecific organic anion transporter mediated transport pathway; amiloride pharmacodynamics pathway; bendroflumethiazide pharmacodynamics pathway; INTERACTS WITH (-)-citrinin; 1-naphthyl isothiocyanate; 2,2,2-tetramine.
Type: protein-coding
Also known as: MGC124962; Oat1; Orctl1; organic anion transporter 1; organic cationic transporter-like 1; Paht; renal organic anion transporter 1; Roat1; rROAT1; solute carrier family 22 (organic anion transporter) member 6; solute carrier family 22 (organic anion transporter), member 6; solute carrier family 22, member 6
Homo sapiens (human) : SLC22A6 (solute carrier family 22 member 6)  HGNC  Alliance
Mus musculus (house mouse) : Slc22a6 (solute carrier family 22 (organic anion transporter), member 6)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Slc22a6 (solute carrier family 22 member 6)
Pan paniscus (bonobo/pygmy chimpanzee) : SLC22A6 (solute carrier family 22 member 6)
Canis lupus familiaris (dog) : SLC22A6 (solute carrier family 22 member 6)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Slc22a6 (solute carrier family 22 member 6)
Sus scrofa (pig) : SLC22A6 (solute carrier family 22 member 6)
more info ...
Is Marker For: Strains:   SD-Slc22a6em1Sage  
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.01224,824,809 - 224,833,284 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1224,824,799 - 224,833,259 (+)Ensembl
Rnor_5.01231,761,600 - 231,772,550 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41211,294,178 - 211,302,398 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11211,452,399 - 211,460,822 (+)NCBI
Celera1203,036,078 - 203,044,298 (+)NCBICelera
Cytogenetic Map1q43NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
QTLs in Region (Rnor_6.0)
Related Rat Strains
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Slc22a6
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 69338
Created: 2001-11-14
Species: Rattus norvegicus
Last Modified: 2019-11-27
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.