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Gene: Fth1 (ferritin heavy chain 1) Rattus norvegicus
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Symbol: Fth1
Name: ferritin heavy chain 1
Description: Predicted to have ferric iron binding activity; ferrous iron binding activity; and ferroxidase activity. Involved in negative regulation of fibroblast proliferation and negative regulation of necrotic cell death. Predicted to localize to autolysosome. Biomarker of congestive heart failure and hepatocellular carcinoma. Human ortholog(s) of this gene implicated in hemochromatosis type 5. Orthologous to human FTH1 (ferritin heavy chain 1); PARTICIPATES IN iron storage pathway; porphyrin and chlorophyll metabolic pathway; INTERACTS WITH 2-acetamidofluorene; 3-chloropropane-1,2-diol; acrylamide.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: ferritin H subunit; ferritin heavy chain; Ferritin subunit H; ferritin, heavy polypeptide 1; Fth
Orthologs:
Homo sapiens (human) : FTH1 (ferritin heavy chain 1)  HGNC  Alliance
Mus musculus (house mouse) : Fth1 (ferritin heavy polypeptide 1)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Fth1 (ferritin heavy chain 1)
Pan paniscus (bonobo/pygmy chimpanzee) : FTH1 (ferritin heavy chain 1)
Canis lupus familiaris (dog) : FTH1 (ferritin heavy chain 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Fth1 (ferritin heavy chain 1)
Sus scrofa (pig) : FTH1 (ferritin heavy chain 1)
Chlorocebus sabaeus (African green monkey) : FTH1 (ferritin heavy chain 1)
Heterocephalus glaber (naked mole-rat) : Fth1 (ferritin heavy chain 1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01226,030,940 - 226,033,228 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1226,030,938 - 226,033,228 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01232,979,122 - 232,981,410 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41212,430,453 - 212,432,741 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11212,588,882 - 212,591,171 (+)NCBI
Celera1204,122,676 - 204,124,964 (+)NCBICelera
Cytogenetic Map1q43NCBI
RH 3.4 Map14258.8RGD
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Fth1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 2635
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2020-06-09
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.