GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Fth1 | multiple interactions | EXP | | 6480464 | CTD | [Deferoxamine results in decreased abundance of Iron] which results in decreased expression of FTH1 mRNA; Iron deficiency promotes the reaction [Vitamin A deficiency results in decreased expression of FTH1 protein] | PMID:15893546 PMID:22154532 | Fth1 | affects abundance | ISO | Fth1 (Mus musculus) | 6480464 | CTD | FTH1 protein affects the abundance of Iron | PMID:16448386 | Fth1 | affects binding | ISO | FTH1 (Homo sapiens) | 6480464 | CTD | Iron binds to FTH1 protein | PMID:17070541 | Fth1 | affects metabolic processing | ISO | Fth1 (Mus musculus) | 6480464 | CTD | FTH1 protein affects the metabolism of Iron | PMID:17194590 | Fth1 | decreases expression | ISO | Fth1 (Mus musculus) | 6480464 | CTD | Iron results in decreased expression of FTH1 mRNA | PMID:16424395 | Fth1 | increases expression | ISO | Fth1 (Mus musculus) | 6480464 | CTD | Iron results in increased expression of FTH1 mRNA | PMID:16424395 | Fth1 | multiple interactions | ISO | Fth1 (Mus musculus) | 6480464 | CTD | [CP gene mutant form results in increased abundance of Iron] which results in increased expression of FTH1 mRNA; [Iron-Dextran Complex results in increased abundance of Iron] which results in increased expression of FTH1 mRNA; FTH1 protein inhibits the reaction [Iron results in increased abundance of Reactive Oxygen Species] | PMID:16988052 PMID:18931039 PMID:33393188 | Fth1 | multiple interactions | ISO | FTH1 (Homo sapiens) | 6480464 | CTD | [[NBD peptide, mouse results in decreased expression of FTH1 mRNA] which results in increased abundance of Iron] which results in increased abundance of Reactive Oxygen Species; [Iron-Dextran Complex results in increased abundance of Iron] which results in increased expression of FTH1 protein; astragaloside A inhibits the reaction [[Iron-Dextran Complex results in increased abundance of Iron] which results in increased expression of FTH1 protein]; Deferiprone inhibits the reaction [[Iron-Dextran Complex results in increased abundance of Iron] which results in increased expression of FTH1 protein] | PMID:19258503 PMID:33285147 | | ||||||||||||||||||||||
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