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Gene: Men1 (menin 1) Rattus norvegicus
Symbol: Men1
Name: menin 1
RGD ID: 3078
Description: Exhibits chromatin binding activity. Predicted to contribute to histone-lysine N-methyltransferase activity. Involved in several processes, including animal organ development; regulation of epithelial cell proliferation; and regulation of transcription by RNA polymerase II. Localizes to nucleus. Human ortholog(s) of this gene implicated in endocrine gland cancer (multiple); hyperparathyroidism; and multiple endocrine neoplasia type 1. Orthologous to human MEN1 (menin 1); PARTICIPATES IN histone modification pathway; INTERACTS WITH 2,6-dinitrotoluene; ammonium chloride; bisphenol A.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: menin; MGC114329; multiple endocrine neoplasia 1; multiple endocrine neoplasia I; multiple endocrine neoplasia type I
Homo sapiens (human) : MEN1 (menin 1)  HGNC  Alliance
Mus musculus (house mouse) : Men1 (multiple endocrine neoplasia 1)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Men1 (menin 1)
Pan paniscus (bonobo/pygmy chimpanzee) : MEN1 (menin 1)
Canis lupus familiaris (dog) : MEN1 (menin 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Men1 (menin 1)
Sus scrofa (pig) : MEN1 (menin 1)
Chlorocebus sabaeus (African green monkey) : MEN1 (menin 1)
Heterocephalus glaber (naked mole-rat) : Men1 (menin 1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.01221,704,394 - 221,710,343 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1221,704,493 - 221,710,331 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01228,692,520 - 228,698,433 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41209,114,987 - 209,120,837 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11209,273,349 - 209,279,258 (+)NCBI
Celera1201,172,444 - 201,178,294 (+)NCBICelera
Cytogenetic Map1q43NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Men1
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 3078
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2020-09-23
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.