Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: Rela (RELA proto-oncogene, NF-kB subunit) Rattus norvegicus
Analyze
Symbol: Rela
Name: RELA proto-oncogene, NF-kB subunit
Description: Exhibits RNA polymerase II proximal promoter sequence-specific DNA binding activity and transcription factor binding activity. Involved in several processes, including aging; positive regulation of cell differentiation; and positive regulation of pri-miRNA transcription by RNA polymerase II. Localizes to several cellular components, including the cytosol; nuclear chromatin; and protein-containing complex. Used to study encephalitis; fatty liver disease; and status epilepticus. Biomarker of artery disease (multiple); colitis; end stage renal failure; epilepsy; and uveitis. Human ortholog(s) of this gene implicated in ductal carcinoma in situ; lung non-small cell carcinoma; lymphoma; and renal cell carcinoma. Orthologous to human RELA (RELA proto-oncogene, NF-kB subunit); PARTICIPATES IN ceramide signaling pathway; interleukin-1 signaling pathway; interleukin-12 signaling pathway; INTERACTS WITH (+)-alpha-tocopherol; (+)-schisandrin B; (+)-Tetrandrine.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: NFkB; nos2; nuclear factor kappa B subunit p65; nuclear factor kappaB subunit p65; transcription factor p65; v-rel avian reticuloendotheliosis viral oncogene homolog A; v-rel reticuloendotheliosis viral oncogene homolog A; v-rel reticuloendotheliosis viral oncogene homolog A (avian)
Orthologs:
Homo sapiens (human) : RELA (RELA proto-oncogene, NF-kB subunit)  HGNC  Alliance
Mus musculus (house mouse) : Rela (v-rel reticuloendotheliosis viral oncogene homolog A (avian))  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Rela (RELA proto-oncogene, NF-kB subunit)
Pan paniscus (bonobo/pygmy chimpanzee) : RELA (RELA proto-oncogene, NF-kB subunit)
Canis lupus familiaris (dog) : RELA (RELA proto-oncogene, NF-kB subunit)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Rela (RELA proto-oncogene, NF-kB subunit)
Sus scrofa (pig) : RELA (RELA proto-oncogene, NF-kB subunit)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01220,992,770 - 221,003,249 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01227,928,092 - 227,938,571 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41208,262,669 - 208,273,148 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11208,416,121 - 208,426,601 (+)NCBI
Celera1200,460,753 - 200,471,232 (+)NCBICelera
Cytogenetic Map1q43NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model