Nps (neuropeptide S) - Rat Genome Database

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Gene: Nps (neuropeptide S) Rattus norvegicus
Analyze
Symbol: Nps
Name: neuropeptide S
RGD ID: 2324597
Description: Involved in positive regulation of circadian sleep/wake cycle, wakefulness. Predicted to be located in synapse. Used to study morphine dependence. Orthologous to human NPS (neuropeptide S); INTERACTS WITH bisphenol A; dizocilpine maleate; 1,2-dichloroethane (ortholog).
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: LOC100360071; Neuropeptide S-like
RGD Orthologs
Human
Mouse
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21190,077,040 - 190,080,821 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1190,077,040 - 190,080,821 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1198,437,750 - 198,441,531 (+)NCBIRnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.01205,597,306 - 205,601,071 (+)NCBIRnor_SHRSP
UTH_Rnor_WKY_Bbb_1.01198,270,805 - 198,274,570 (+)NCBIRnor_WKY
Rnor_6.01207,508,414 - 207,512,195 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1207,508,414 - 207,512,195 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01214,442,729 - 214,446,510 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41194,887,958 - 194,892,866 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1187,793,965 - 187,797,746 (+)NCBICelera
Cytogenetic Map1q41NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Morphine dependence is associated with changes in neuropeptide S receptor expression and function in rat brain. Ghazal P, etal., Peptides. 2013 Aug;46:6-12. doi: 10.1016/j.peptides.2013.05.001. Epub 2013 May 16.
3. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
4. Neuropeptide S receptor gene expression in alcohol withdrawal and protracted abstinence in postdependent rats. Ruggeri B, etal., Alcohol Clin Exp Res. 2010 Jan;34(1):90-7. doi: 10.1111/j.1530-0277.2009.01070.x. Epub 2009 Oct 23.
5. Neuropeptide S promotes wakefulness through activation of the posterior hypothalamic histaminergic and orexinergic neurons. Zhao P, etal., Neuroscience. 2012 Apr 5;207:218-26. doi: 10.1016/j.neuroscience.2012.01.022. Epub 2012 Jan 20.
Additional References at PubMed
PMID:15312648   PMID:15919054   PMID:17645946   PMID:18564106   PMID:19429110   PMID:20495497   PMID:20974945   PMID:21437203   PMID:21452235   PMID:21861171   PMID:25986404   PMID:26227793  
PMID:26462664   PMID:27224019   PMID:28433253   PMID:28805209   PMID:29118105   PMID:29157796   PMID:32044336   PMID:32441169   PMID:36195130  


Genomics

Comparative Map Data
Nps
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21190,077,040 - 190,080,821 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1190,077,040 - 190,080,821 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1198,437,750 - 198,441,531 (+)NCBIRnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.01205,597,306 - 205,601,071 (+)NCBIRnor_SHRSP
UTH_Rnor_WKY_Bbb_1.01198,270,805 - 198,274,570 (+)NCBIRnor_WKY
Rnor_6.01207,508,414 - 207,512,195 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1207,508,414 - 207,512,195 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01214,442,729 - 214,446,510 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41194,887,958 - 194,892,866 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1187,793,965 - 187,797,746 (+)NCBICelera
Cytogenetic Map1q41NCBI
NPS
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3810127,549,309 - 127,553,540 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl10127,549,309 - 127,553,540 (+)EnsemblGRCh38hg38GRCh38
GRCh3710129,347,573 - 129,351,804 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 3610129,237,603 - 129,240,925 (+)NCBINCBI36Build 36hg18NCBI36
Celera10123,018,049 - 123,021,372 (+)NCBICelera
Cytogenetic Map10q26.2NCBI
HuRef10122,920,598 - 122,923,921 (+)NCBIHuRef
CHM1_110129,629,918 - 129,633,240 (+)NCBICHM1_1
T2T-CHM13v2.010128,444,335 - 128,448,567 (+)NCBIT2T-CHM13v2.0
Nps
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm397134,870,348 - 134,874,671 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl7134,860,432 - 134,874,671 (+)EnsemblGRCm39 Ensembl
GRCm387135,268,619 - 135,272,942 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl7135,258,703 - 135,272,942 (+)EnsemblGRCm38mm10GRCm38
MGSCv377142,460,302 - 142,464,625 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv367142,436,414 - 142,464,444 (+)NCBIMGSCv36mm8
Celera7135,088,015 - 135,092,338 (+)NCBICelera
Cytogenetic Map7F3NCBI
NPS
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.110128,384,897 - 128,388,217 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl10128,384,897 - 128,388,217 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v010124,135,616 - 124,139,845 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
NPS
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12836,488,430 - 36,492,524 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2836,488,500 - 36,492,090 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2836,544,343 - 36,548,486 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02837,120,629 - 37,124,769 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2837,120,699 - 37,124,289 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12836,596,914 - 36,601,058 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02836,595,559 - 36,599,690 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02836,850,200 - 36,854,347 (+)NCBIUU_Cfam_GSD_1.0
Nps
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440721310,385,430 - 10,389,542 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493648615,172,256 - 15,175,339 (+)EnsemblSpeTri2.0
SpeTri2.0NW_00493648615,172,068 - 15,175,568 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
NPS
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl14136,836,352 - 136,839,510 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.114136,835,630 - 136,839,511 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.214148,566,054 - 148,569,278 (-)NCBISscrofa10.2Sscrofa10.2susScr3
NPS
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.19120,168,749 - 120,176,288 (+)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366604881,554,586 - 81,558,810 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Nps
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462473719,447,495 - 19,451,005 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Nps
23 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:72
Count of miRNA genes:64
Interacting mature miRNAs:67
Transcripts:ENSRNOT00000054896
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
10059597Bp377Blood pressure QTL 3773.420.025arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)132737458199368955Rat
634314Niddm44Non-insulin dependent diabetes mellitus QTL 44blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)149393289199050459Rat
1578780Cm52Cardiac mass QTL 523.30.0001heart mass (VT:0007028)heart wet weight (CMO:0000069)181591954219808434Rat
1331749Hrtrt11Heart rate QTL 112.973heart pumping trait (VT:2000009)heart rate (CMO:0000002)194494440198211706Rat
70209Niddm23Non-insulin dependent diabetes mellitus QTL 232.82blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)194494440198324465Rat
731168Bp154Blood pressure QTL 1543.4arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)194642722214537671Rat
1354591Cm36Cardiac mass QTL 364.1heart left ventricle mass (VT:0007031)calculated heart weight (CMO:0000073)1102813953201278233Rat
1354615Cm32Cardiac mass QTL 325.2heart left ventricle mass (VT:0007031)heart left ventricle wet weight (CMO:0000071)1102813953201278233Rat
1354606Bp246Blood pressure QTL 2463.6arterial blood pressure trait (VT:2000000)pulse pressure (CMO:0000292)1102813953218753816Rat
7794788Mcs32Mammary carcinoma susceptibility QTL 322.61mammary gland integrity trait (VT:0010552)mammary tumor incidence/prevalence measurement (CMO:0000946)1115540693238914717Rat
7421630Bp362Blood pressure QTL 3620.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1118608292241799120Rat
631205Bp196Blood pressure QTL 19640.0001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1118944897199050459Rat
631549Bp89Blood pressure QTL 895.7arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1123350581201284552Rat
1598853Memor3Memory QTL 34.5exploratory behavior trait (VT:0010471)total horizontal distance resulting from voluntary locomotion in an experimental apparatus (CMO:0001443)1143506580212458660Rat
61348Bp30Blood pressure QTL 302.4arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1144017057197814409Rat
70160Bw18Body weight QTL 185.7body mass (VT:0001259)body weight (CMO:0000012)1144267353196383635Rat
737828Hcas3Hepatocarcinoma susceptibility QTL 34.9liver integrity trait (VT:0010547)liver tumorous lesion volume to total liver volume ratio (CMO:0001082)1144267353222987745Rat
2302378Insul11Insulin level QTL 113.25blood insulin amount (VT:0001560)serum insulin level (CMO:0000358)1144267353251128347Rat
7771612Cm80Cardiac mass QTL 808.4heart left ventricle mass (VT:0007031)heart left ventricle weight (CMO:0000776)1149448574221264292Rat
724531Uae5Urinary albumin excretion QTL 54urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)1150700142252085212Rat
1578759Uae30Urinary albumin excretion QTL 303.30.003urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)1150700247252085048Rat
1578778Pur4Proteinuria QTL 43.30.003urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)1150700247252085048Rat
1354602Bw35Body weight QTL 3512.2body mass (VT:0001259)body weight (CMO:0000012)1151162512201278233Rat
1354620Kidm19Kidney mass QTL 194kidney mass (VT:0002707)calculated kidney weight (CMO:0000160)1151162512201278233Rat
1354634Kidm12Kidney mass QTL 123.9kidney mass (VT:0002707)right kidney wet weight (CMO:0000082)1151162512201278233Rat
1354636Lmblg1Limb length QTL 16.4tibia length (VT:0004357)tibia length (CMO:0000450)1151162512201278233Rat
1354610Bw34Body weight QTL 344.1body mass (VT:0001259)body weight (CMO:0000012)1151162512256448636Rat
1354646Kidm18Kidney mass QTL 185.7kidney mass (VT:0002707)calculated kidney weight (CMO:0000160)1151162512256448636Rat
1354661Bw33Body weight QTL 335.2body mass (VT:0001259)body weight (CMO:0000012)1151162512256448636Rat
1358886Bp260Blood pressure QTL 2603.67arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1151162766225824951Rat
61343Bp28Blood pressure QTL 28arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1151646613196646613Rat
1549837Hcar15Hepatocarcinoma resistance QTL 150.05liver integrity trait (VT:0010547)liver tumorous lesion number (CMO:0001068)1153136852260522016Rat
2303622Vencon6Ventilatory control QTL 60.001respiration trait (VT:0001943)respiration rate (CMO:0000289)1154561505199561505Rat
4889428Stresp24Stress response QTL 240.05heart pumping trait (VT:2000009)absolute change in electrocardiographic low frequency R-R spectral component to high frequency R-R spectral component ratio (CMO:0002162)1155866514200866514Rat
1354618Kidm15Kidney mass QTL 155kidney mass (VT:0002707)left kidney wet weight (CMO:0000083)1156677124201278233Rat
2312420Pur17Proteinuria QTL 177.10.0001urine protein amount (VT:0005160)urine total protein excretion rate (CMO:0000756)1156677124218753816Rat
1354580Scort1Serum corticosterone level QTL 13.4blood corticosterone amount (VT:0005345)blood corticosterone level (CMO:0001172)1156677124256448636Rat
61347Bp197Blood pressure QTL 1974.2arterial blood pressure trait (VT:2000000)blood pressure measurement (CMO:0000003)1158633083203633083Rat
2292222Bp307Blood pressure QTL 3073.060.0014arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1164310393213533942Rat
2292220Bp306Blood pressure QTL 3063.470.00087arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1164310393243914901Rat
619613Bp77Blood pressure QTL 770.01arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1164747424209747424Rat
619613Bp77Blood pressure QTL 770.01arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)1164747424209747424Rat
2312558Glom17Glomerulus QTL 173.90.001kidney glomerulus morphology trait (VT:0005325)index of glomerular damage (CMO:0001135)1166532971191278129Rat
1354653Despr9Despair related QTL 90.00019locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)1167909849212909849Rat
619614Bp78Blood pressure QTL 780.001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1169112897197261052Rat
619614Bp78Blood pressure QTL 780.001arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)1169112897197261052Rat
61341Bp26Blood pressure QTL 26arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1169537671214537671Rat
724562Rends1Renal damage susceptibility QTL 10.05kidney glomerulus integrity trait (VT:0010546)index of glomerular damage (CMO:0001135)1169537671214537671Rat
1358294Bw37Body weight QTL 3750.000011body mass (VT:0001259)body weight (CMO:0000012)1171310381216310381Rat
2293689Bss47Bone structure and strength QTL 477.250.0001lumbar vertebra size trait (VT:0010518)lumbar vertebra trabecular cross-sectional area (CMO:0001692)1171629477216629477Rat
2293693Bss22Bone structure and strength QTL 2233.520.0001femur morphology trait (VT:0000559)femur cross-sectional area (CMO:0001661)1171629477216629477Rat
2300161Bmd43Bone mineral density QTL 438.40.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)1171629477216629477Rat
2300174Bmd42Bone mineral density QTL 428.40.0001lumbar vertebra mineral mass (VT:0010511)bone mineral density (CMO:0001226)1171629477216629477Rat
2300187Bmd41Bone mineral density QTL 418.90.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)1171629477216629477Rat
2293654Bss30Bone structure and strength QTL 3032.650.0001femur strength trait (VT:0010010)femur midshaft polar moment of inertia (CMO:0001669)1171629477216629477Rat
2293673Bss27Bone structure and strength QTL 2718.630.0001femur morphology trait (VT:0000559)femur midshaft cortical cross-sectional area (CMO:0001663)1171629477216629477Rat
2293677Bss41Bone structure and strength QTL 419.380.0001lumbar vertebra size trait (VT:0010518)lumbar vertebra cross-sectional area (CMO:0001689)1171629477216629477Rat
1549830Bss1Bone structure and strength QTL 14.8femur strength trait (VT:0010010)femur ultimate force (CMO:0001675)1172609619217609619Rat
631214Bw61Body weight QTL613.40.0001intramuscular adipose amount (VT:0010044)intramuscular fat area (CMO:0001162)1173108781218108781Rat
631670Iddm10Insulin dependent diabetes mellitus QTL 101.9blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)1174133260196383635Rat
70163Bw20Body weight QTL 205.1body mass (VT:0001259)body weight (CMO:0000012)1174133260219133260Rat
738032Hcas5Hepatocarcinoma susceptibility QTL 53.12liver integrity trait (VT:0010547)liver tumorous lesion number (CMO:0001068)1176426412257976495Rat
1600380Niddm70Non-insulin dependent diabetes mellitus QTL 703.10.0008blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)1176550523221550523Rat
10059600Bp378Blood pressure QTL 3783.080.05arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1176869060221869060Rat
1354624Cm35Cardiac mass QTL355.7heart left ventricle mass (VT:0007031)calculated heart weight (CMO:0000073)1177227632256448636Rat
1354652Kidm20Kidney mass QTL 204.3kidney mass (VT:0002707)calculated kidney weight (CMO:0000160)1177227632256448636Rat
1558658Bw59Body weight QTL 593.50.0003body mass (VT:0001259)body weight (CMO:0000012)1178784622223784622Rat
634321Hc1Hypercalciuria QTL 12.91urine calcium amount (VT:0002985)urine calcium excretion rate (CMO:0000763)1178810256240830002Rat
1578763Kidm29Kidney mass QTL 293.30.0001kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)1179567751260522016Rat
1302787Stl25Serum triglyceride level QTL 252.70.0073blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)1180359209210702199Rat
6903303Scl34Serum cholesterol QTL 342.50.0033blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)1180359209218108781Rat
737977Bp160Blood pressure QTL 1600.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1181133855226133855Rat
61378Bp43Blood pressure QTL 4322.6arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1181746937196383635Rat
724559Pancm1Pancreatic morphology QTL 17.1islet of Langerhans morphology trait (VT:0005215)pancreatic islet damage composite score (CMO:0001156)1181759564214537555Rat
2293083Iddm25Insulin dependent diabetes mellitus QTL 254.18blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)1181829673224569684Rat
634312Bp143Blood pressure QTL 14330.0002arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1182623426219932796Rat
8655655Arrd2Age-related retinal degeneration QTL 27.79retinal layer morphology trait (VT:0003727)percentage of study population developing retinopathy during a period of time (CMO:0002453)1183970203243914901Rat
8655855Arrd3Age-related retinal degeneration QTL 33.07lens clarity trait (VT:0001304)cataract incidence/prevalence measurement (CMO:0001585)1183970203243914901Rat
631838Niddm36Non-insulin dependent diabetes mellitus QTL 360.01insulin secretion trait (VT:0003564)calculated pancreatic islet insulin release measurement (CMO:0001217)1184550676229550676Rat
1300145Rf7Renal function QTL 72.96urine creatinine amount (VT:0010540)urine creatinine level (CMO:0000125)1185145134221264292Rat
1359018Hrtrt20Heart rate QTL 203.08heart pumping trait (VT:2000009)heart rate (CMO:0000002)1185356336202902618Rat
2312564Glom18Glomerulus QTL 182.40.003kidney glomerulus morphology trait (VT:0005325)index of glomerular damage (CMO:0001135)1185356336231689108Rat
1582206Kidm33Kidney mass QTL 336.9kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)1188377360224054420Rat
6480780Insul18Insulin level QTL 184.11blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)1189607473200611765Rat


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

endocrine system hemolymphoid system nervous system reproductive system respiratory system
High
Medium
Low 14
Below cutoff 1 1 14 3 1

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001271113 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide JACYVU010000044 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSRNOT00000054896   ⟹   ENSRNOP00000051780
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1190,077,040 - 190,080,821 (+)Ensembl
Rnor_6.0 Ensembl1207,508,414 - 207,512,195 (+)Ensembl
RefSeq Acc Id: NM_001271113   ⟹   NP_001258042
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21190,077,040 - 190,080,821 (+)NCBI
Rnor_6.01207,508,414 - 207,512,195 (+)NCBI
Rnor_5.01214,442,729 - 214,446,510 (+)NCBI
Celera1187,793,965 - 187,797,746 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_001258042 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein P0C0P7 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: NP_001258042   ⟸   NM_001271113
- Peptide Label: precursor
- UniProtKB: P0C0P7 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: ENSRNOP00000051780   ⟸   ENSRNOT00000054896

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P0C0P7-F1-model_v2 AlphaFold P0C0P7 1-89 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:2324597 AgrOrtholog
BioCyc Gene G2FUF-57161 BioCyc
Ensembl Genes ENSRNOG00000036653 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Protein ENSRNOP00000051780 ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000054896 ENTREZGENE, UniProtKB/Swiss-Prot
InterPro Neuropeptide_S UniProtKB/Swiss-Prot
KEGG Report rno:100360071 UniProtKB/Swiss-Prot
NCBI Gene 100360071 ENTREZGENE
PANTHER PTHR36679 UniProtKB/Swiss-Prot
Pfam Neuropeptide_S UniProtKB/Swiss-Prot
PhenoGen Nps PhenoGen
UniProt NPS_RAT UniProtKB/Swiss-Prot, ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2011-12-21 Nps  neuropeptide S  LOC100360071  Neuropeptide S-like  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2010-05-06 LOC100360071  Neuropeptide S-like      Symbol and Name status set to provisional 70820 PROVISIONAL