Nxf1 (nuclear RNA export factor 1) - Rat Genome Database

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Gene: Nxf1 (nuclear RNA export factor 1) Rattus norvegicus
Analyze
Symbol: Nxf1
Name: nuclear RNA export factor 1
RGD ID: 62014
Description: Predicted to enable mRNA binding activity. Predicted to be involved in poly(A)+ mRNA export from nucleus. Predicted to act upstream of or within RNA export from nucleus. Predicted to be located in cytoplasm; nuclear inclusion body; and nuclear speck. Predicted to be part of nuclear RNA export factor complex; nuclear pore; and transcription export complex. Predicted to be active in nucleus. Orthologous to human NXF1 (nuclear RNA export factor 1); PARTICIPATES IN NXF1-NXT1 export pathway; influenza A pathway; mRNA decay pathway; INTERACTS WITH 17beta-estradiol; 2,4-dinitrotoluene; 2,6-dinitrotoluene.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: Mex67h; Mex67h-pending; mRNA export factor TAP; nuclear RNA export factor 1 homolog; nuclear RNA export factor 1 homolog (S. cerevisiae); Tap; tip associating protein; tip-associated protein; tip-associating protein
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81215,084,563 - 215,097,756 (+)NCBIGRCr8
mRatBN7.21205,655,442 - 205,668,637 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1205,655,375 - 205,668,636 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1214,062,638 - 214,077,055 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01221,098,997 - 221,112,188 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01213,791,700 - 213,804,891 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01224,957,535 - 224,970,728 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1224,957,517 - 224,970,727 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01231,895,708 - 231,908,901 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41211,428,605 - 211,441,798 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11211,587,034 - 211,600,227 (+)NCBI
Celera1203,168,372 - 203,181,566 (+)NCBICelera
Cytogenetic Map1q43NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Nxf1Ratintellectual disability  ISONXF1 (Homo sapiens)8554872ClinVar Annotator: match by term: Intellectual disabilityClinVar 
Nxf1Ratleukocyte adhesion deficiency 3  ISONXF1 (Homo sapiens)8554872ClinVar Annotator: match by term: Leukocyte adhesion deficiency 3ClinVarPMID:28492532

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Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Nxf1Rat(-)-epigallocatechin 3-gallate multiple interactionsISONXF1 (Homo sapiens)6480464[potassium chromate(VI) co-treated with epigallocatechin gallate] results in increased expression of NXF1 mRNACTDPMID:22079256
Nxf1Rat1,2-dimethylhydrazine increases expressionISONxf1 (Mus musculus)64804641 and 2-Dimethylhydrazine results in increased expression of NXF1 mRNACTDPMID:22206623
Nxf1Rat17alpha-ethynylestradiol multiple interactionsISONxf1 (Mus musculus)6480464[Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of NXF1 mRNACTDPMID:17942748
Nxf1Rat17beta-estradiol affects expressionISONxf1 (Mus musculus)6480464Estradiol affects the expression of NXF1 mRNACTDPMID:15598610
Nxf1Rat17beta-estradiol decreases expressionEXP 6480464Estradiol results in decreased expression of NXF1 mRNACTDPMID:35192832
Nxf1Rat2,3,7,8-tetrachlorodibenzodioxine multiple interactionsISONxf1 (Mus musculus)6480464[Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of NXF1 mRNACTDPMID:17942748
Nxf1Rat2,3,7,8-tetrachlorodibenzodioxine affects expressionISONxf1 (Mus musculus)6480464Tetrachlorodibenzodioxin affects the expression of NXF1 mRNACTDPMID:21570461
Nxf1Rat2,4,6-tribromophenol decreases expressionISONXF1 (Homo sapiens)64804642 more ...CTDPMID:31675489
Nxf1Rat2,4-dinitrotoluene affects expressionEXP 64804642 and 4-dinitrotoluene affects the expression of NXF1 mRNACTDPMID:21346803
Nxf1Rat2,6-dinitrotoluene affects expressionEXP 64804642 and 6-dinitrotoluene affects the expression of NXF1 mRNACTDPMID:21346803
Nxf1Rat3-isobutyl-1-methyl-7H-xanthine multiple interactionsISONXF1 (Homo sapiens)6480464[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in decreased expression of NXF1 mRNA and [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol S] results in decreased expression of NXF1 mRNACTDPMID:28628672
Nxf1Rat3H-1,2-dithiole-3-thione decreases expressionEXP 64804641 and 2-dithiol-3-thione results in decreased expression of NXF1 mRNACTDPMID:19162173
Nxf1Rat4,4'-sulfonyldiphenol multiple interactionsISONXF1 (Homo sapiens)6480464[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol S] results in decreased expression of NXF1 mRNACTDPMID:28628672
Nxf1Rat6-propyl-2-thiouracil decreases expressionEXP 6480464Propylthiouracil results in decreased expression of NXF1 mRNACTDPMID:30047161
Nxf1Ratacrolein multiple interactionsISONXF1 (Homo sapiens)6480464[Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in decreased expression of NXF1 mRNA and [Air Pollutants results in increased abundance of [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone]] which results in decreased expression of NXF1 mRNACTDPMID:32699268
Nxf1Ratacrylamide increases expressionISONXF1 (Homo sapiens)6480464Acrylamide results in increased expression of NXF1 mRNACTDPMID:32763439
Nxf1Rataflatoxin B1 increases expressionISONXF1 (Homo sapiens)6480464Aflatoxin B1 results in increased expression of NXF1 mRNACTDPMID:22100608
Nxf1Ratall-trans-retinoic acid increases expressionISONXF1 (Homo sapiens)6480464Tretinoin results in increased expression of NXF1 mRNACTDPMID:33167477
Nxf1Ratalpha-pinene multiple interactionsISONXF1 (Homo sapiens)6480464[Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in decreased expression of NXF1 mRNA and [Air Pollutants results in increased abundance of [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone]] which results in decreased expression of NXF1 mRNACTDPMID:32699268
Nxf1Ratamitrole decreases expressionEXP 6480464Amitrole results in decreased expression of NXF1 mRNACTDPMID:30047161

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Biological Process
1 to 13 of 13 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Nxf1Ratbiological_process  ND 159840712/2015: no relevant rat dataRGD 
Nxf1RatmRNA export from nucleus involved_inIEAInterPro:IPR0152451600115GO_REF:0000002InterProGO_REF:0000002
Nxf1RatmRNA export from nucleus involved_inIEAUniProtKB:Q9UBU9 and ensembl:ENSP000002941721600115GO_REF:0000107EnsemblGO_REF:0000107
Nxf1RatmRNA export from nucleus involved_inISONXF1 (Homo sapiens)1624291 PMID:19165146 more ...RGDPMID:19165146 more ...
Nxf1RatmRNA export from nucleus involved_inISSUniProtKB:Q9UBU91600115GO_REF:0000024UniProtGO_REF:0000024
Nxf1RatmRNA transport involved_inIEAUniProtKB-KW:KW-05091600115GO_REF:0000043UniProtGO_REF:0000043
Nxf1RatmRNA transport involved_inIEAInterPro:IPR0056371600115GO_REF:0000002InterProGO_REF:0000002
Nxf1Ratpoly(A)+ mRNA export from nucleus acts_upstream_of_or_withinIEAUniProtKB:Q99JX7 and ensembl:ENSMUSP000000102411600115GO_REF:0000107EnsemblGO_REF:0000107
Nxf1Ratpoly(A)+ mRNA export from nucleus acts_upstream_of_or_withinISONxf1 (Mus musculus)1624291PR:Q9QZV9 more ...RGDPMID:15820316
Nxf1Ratpoly(A)+ mRNA export from nucleus involved_inIBAFB:FBgn0003321 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Nxf1Ratprotein transport involved_inIEAUniProtKB-KW:KW-0653 and UniProtKB-KW:KW-08111600115GO_REF:0000043UniProtGO_REF:0000043
Nxf1RatRNA export from nucleus acts_upstream_of_or_withinISONxf1 (Mus musculus)1624291 PMID:11579093RGDPMID:11579093
Nxf1RatRNA export from nucleus acts_upstream_of_or_withinIEAUniProtKB:Q99JX7 and ensembl:ENSMUSP000000102411600115GO_REF:0000107EnsemblGO_REF:0000107
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Cellular Component
1 to 20 of 33 rows

  
Object Symbol
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Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Nxf1Ratcytoplasm located_inIEAInterPro:IPR0152451600115GO_REF:0000002InterProGO_REF:0000002
Nxf1Ratcytoplasm located_inIEAUniProtKB-KW:KW-09631600115GO_REF:0000043UniProtGO_REF:0000043
Nxf1Ratcytoplasm located_inISONXF1 (Homo sapiens)1624291 PMID:19864460RGDPMID:19864460
Nxf1Ratcytoplasm located_inIEAUniProtKB:Q9UBU9 and ensembl:ENSP000002941721600115GO_REF:0000107EnsemblGO_REF:0000107
Nxf1Ratcytoplasm located_inIEAUniProtKB-SubCell:SL-00861600115GO_REF:0000044UniProtGO_REF:0000044
Nxf1Ratcytoplasmic stress granule located_inIEAUniProtKB-SubCell:SL-04961600115GO_REF:0000044UniProtGO_REF:0000044
Nxf1Ratnuclear envelope located_inIEAUniProtKB-SubCell:SL-01781600115GO_REF:0000044UniProtGO_REF:0000044
Nxf1Ratnuclear inclusion body located_inIEAUniProtKB:Q99JX7 and ensembl:ENSMUSP000000102411600115GO_REF:0000107EnsemblGO_REF:0000107
Nxf1Ratnuclear inclusion body located_inISONxf1 (Mus musculus)1624291 PMID:15615787RGDPMID:15615787
Nxf1Ratnuclear pore part_ofIEAUniProtKB:Q99JX7 and ensembl:ENSMUSP000000102411600115GO_REF:0000107EnsemblGO_REF:0000107
Nxf1Ratnuclear pore part_ofIEAUniProtKB-SubCell:SL-01851600115GO_REF:0000044UniProtGO_REF:0000044
Nxf1Ratnuclear pore part_ofISONxf1 (Mus musculus)1624291 PMID:11579093RGDPMID:11579093
Nxf1Ratnuclear pore part_ofIEAUniProtKB-KW:KW-09061600115GO_REF:0000043UniProtGO_REF:0000043
Nxf1Ratnuclear RNA export factor complex part_ofIEAUniProtKB:Q9UBU9 and ensembl:ENSP000002941721600115GO_REF:0000107EnsemblGO_REF:0000107
Nxf1Ratnuclear RNA export factor complex part_ofISONXF1 (Homo sapiens)1624291 PMID:25628361RGDPMID:25628361
Nxf1Ratnuclear speck located_inISSUniProtKB:Q9UBU91600115GO_REF:0000024UniProtGO_REF:0000024
Nxf1Ratnuclear speck located_inIEAUniProtKB:Q9UBU9 and ensembl:ENSP000002941721600115GO_REF:0000107EnsemblGO_REF:0000107
Nxf1Ratnuclear speck located_inIEAUniProtKB-SubCell:SL-01861600115GO_REF:0000044UniProtGO_REF:0000044
Nxf1Ratnuclear speck located_inISONXF1 (Homo sapiens)1624291 PMID:23826332RGDPMID:23826332
Nxf1Ratnucleoplasm located_inISONXF1 (Homo sapiens) more ...1624291 RGDGO_REF:0000052
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Molecular Function
1 to 12 of 12 rows

  
1 to 12 of 12 rows

RGD Manual Annotations


  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Nxf1RatNXF1-NXT1 export pathway  ISONXF1 (Homo sapiens)9743967 RGD 

Imported Annotations - KEGG (archival)

Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Nxf1Ratinfluenza A pathway  IEA 6907045 KEGGrno:05164
Nxf1RatmRNA decay pathway  IEA 6907045 KEGGrno:03015
Nxf1Ratribosome biogenesis pathway   IEA 6907045 KEGGrno:03008
Nxf1RatRNA transport pathway  IEA 6907045 KEGGrno:03013

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#
Reference Title
Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
3. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
4. The mammalian RNA-binding protein Staufen2 links nuclear and cytoplasmic RNA processing pathways in neurons. Monshausen M, etal., Neuromolecular Med. 2004;6(2-3):127-44.
5. Postage for the messenger: designating routes for nuclear mRNA export. Natalizio BJ and Wente SR, Trends Cell Biol. 2013 Aug;23(8):365-73. doi: 10.1016/j.tcb.2013.03.006. Epub 2013 Apr 11.
6. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
7. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
8. GOA pipeline RGD automated data pipeline
9. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
10. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
11. Comprehensive gene review and curation RGD comprehensive gene curation
12. TAP/NXF1, the primary mRNA export receptor, specifically interacts with a neuronal RNA-binding protein HuD. Saito K, etal., Biochem Biophys Res Commun 2004 Aug 20;321(2):291-7.
13. Tentative Sequence Identification Numbers Tentative Sequence Data IDs. TIGR Gene Index, Rat Data
1 to 13 of 13 rows
PMID:11579093   PMID:15615787   PMID:15820316   PMID:19165146   PMID:19864460   PMID:22658674   PMID:22681889   PMID:23299939   PMID:23826332   PMID:25662211   PMID:28984244  



Nxf1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81215,084,563 - 215,097,756 (+)NCBIGRCr8
mRatBN7.21205,655,442 - 205,668,637 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1205,655,375 - 205,668,636 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1214,062,638 - 214,077,055 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01221,098,997 - 221,112,188 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01213,791,700 - 213,804,891 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01224,957,535 - 224,970,728 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1224,957,517 - 224,970,727 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01231,895,708 - 231,908,901 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41211,428,605 - 211,441,798 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11211,587,034 - 211,600,227 (+)NCBI
Celera1203,168,372 - 203,181,566 (+)NCBICelera
Cytogenetic Map1q43NCBI
NXF1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381162,792,130 - 62,805,440 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1162,792,123 - 62,806,302 (-)EnsemblGRCh38hg38GRCh38
GRCh371162,559,602 - 62,572,912 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361162,316,174 - 62,329,540 (-)NCBINCBI36Build 36hg18NCBI36
Build 341162,316,219 - 62,329,529NCBI
Celera1159,888,182 - 59,901,548 (-)NCBICelera
Cytogenetic Map11q12.3NCBI
HuRef1158,888,624 - 58,901,991 (-)NCBIHuRef
CHM1_11162,442,680 - 62,456,046 (-)NCBICHM1_1
T2T-CHM13v2.01162,781,522 - 62,794,833 (-)NCBIT2T-CHM13v2.0
Nxf1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39198,734,467 - 8,748,274 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl198,734,437 - 8,748,286 (+)EnsemblGRCm39 Ensembl
GRCm38198,757,103 - 8,770,910 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl198,757,073 - 8,770,922 (+)EnsemblGRCm38mm10GRCm38
MGSCv37198,831,593 - 8,845,400 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36198,824,148 - 8,837,955 (+)NCBIMGSCv36mm8
Celera198,517,111 - 8,530,801 (+)NCBICelera
Cytogenetic Map19ANCBI
cM Map195.5NCBI
Nxf1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955599439,775 - 454,300 (+)EnsemblChiLan1.0
ChiLan1.0NW_004955599439,773 - 450,834 (+)NCBIChiLan1.0ChiLan1.0
NXF1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2964,017,231 - 64,031,828 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11165,059,923 - 65,074,091 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01158,147,548 - 58,161,393 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11161,501,541 - 61,514,943 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1161,501,546 - 61,514,943 (-)Ensemblpanpan1.1panPan2
NXF1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11853,884,512 - 53,895,168 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1853,884,546 - 53,895,162 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1852,490,545 - 52,501,204 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01854,936,964 - 54,947,631 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1854,936,955 - 54,947,629 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11854,033,593 - 54,044,247 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01853,608,040 - 53,618,708 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01854,404,311 - 54,414,971 (+)NCBIUU_Cfam_GSD_1.0
Nxf1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494710,374,922 - 10,387,572 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936581488,718 - 504,853 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936581488,691 - 501,323 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
NXF1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl28,969,581 - 8,981,984 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.128,968,659 - 8,983,276 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.228,315,196 - 8,327,226 (+)NCBISscrofa10.2Sscrofa10.2susScr3
NXF1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1111,096,289 - 11,111,186 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl111,096,323 - 11,111,632 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666038108,439,809 - 108,454,239 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Nxf1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046249261,247,071 - 1,269,146 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046249261,247,940 - 1,268,968 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

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Variants in Nxf1
33 total Variants

Predicted Target Of
Summary Value
Count of predictions:44
Count of miRNA genes:35
Interacting mature miRNAs:42
Transcripts:ENSRNOT00000026033
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


1 to 10 of 84 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
1578778Pur4Proteinuria QTL 43.30.003urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)1150700247252085048Rat
1354646Kidm18Kidney mass QTL 185.7kidney mass (VT:0002707)calculated kidney weight (CMO:0000160)1151162512256448636Rat
1357335Bw39Body weight QTL 393.3body mass (VT:0001259)body weight (CMO:0000012)1197814409242814409Rat
1578780Cm52Cardiac mass QTL 523.30.0001heart mass (VT:0007028)heart wet weight (CMO:0000069)181591954219808434Rat
2302375Bw83Body weight QTL 834.870.0002body mass (VT:0001259)body weight (CMO:0000012)1197697768242697768Rat
1354652Kidm20Kidney mass QTL 204.3kidney mass (VT:0002707)calculated kidney weight (CMO:0000160)1177227632256448636Rat
2293674Bss39Bone structure and strength QTL 397.10.0001femur strength trait (VT:0010010)femur total energy absorbed before break (CMO:0001677)1201554356246554356Rat
2302378Insul11Insulin level QTL 113.25blood insulin amount (VT:0001560)serum insulin level (CMO:0000358)1144267353251128347Rat
1354653Despr9Despair related QTL 90.00019locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)1167909849212909849Rat
2293673Bss27Bone structure and strength QTL 2718.630.0001femur morphology trait (VT:0000559)femur midshaft cortical cross-sectional area (CMO:0001663)1171629477216629477Rat

1 to 10 of 84 rows



alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 113 91 90 59 25 59 6 218 97 93 45 60 31



Ensembl Acc Id: ENSRNOT00000026033   ⟹   ENSRNOP00000026033
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1205,655,375 - 205,668,623 (+)Ensembl
Rnor_6.0 Ensembl1224,957,517 - 224,970,727 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000097665   ⟹   ENSRNOP00000081812
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1205,659,716 - 205,668,636 (+)Ensembl
RefSeq Acc Id: NM_021579   ⟹   NP_067590
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81215,084,563 - 215,097,756 (+)NCBI
mRatBN7.21205,655,442 - 205,668,637 (+)NCBI
Rnor_6.01224,957,535 - 224,970,728 (+)NCBI
Rnor_5.01231,895,708 - 231,908,901 (+)NCBI
RGSC_v3.41211,428,605 - 211,441,798 (+)RGD
Celera1203,168,372 - 203,181,566 (+)RGD
Sequence:
Protein RefSeqs NP_067590 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAC63367 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000026033
GenBank Protein O88984 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_067590   ⟸   NM_021579
- UniProtKB: F1MA52 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000026033   ⟸   ENSRNOT00000026033
Ensembl Acc Id: ENSRNOP00000081812   ⟸   ENSRNOT00000097665
NTF2   RRM   TAP-C

Name Modeler Protein Id AA Range Protein Structure
AF-O88984-F1-model_v2 AlphaFold O88984 1-618 view protein structure


eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

RGD ID:13690734
Promoter ID:EPDNEW_R1258
Type:initiation region
Name:Nxf1_1
Description:nuclear RNA export factor 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01224,957,518 - 224,957,578EPDNEW


1 to 39 of 39 rows
Database
Acc Id
Source(s)
BioCyc Gene G2FUF-56500 BioCyc
Ensembl Genes ENSRNOG00000019069 Ensembl, ENTREZGENE
Ensembl Transcript ENSRNOT00000026033 ENTREZGENE
Gene3D-CATH 3.10.450.50 UniProtKB/Swiss-Prot
  3.30.70.330 UniProtKB/Swiss-Prot
  3.80.10.10 UniProtKB/Swiss-Prot
  DNA helicase RuvA subunit, C-terminal domain UniProtKB/Swiss-Prot
InterPro Leu-rich_rpt UniProtKB/Swiss-Prot
  LRR_dom_sf UniProtKB/Swiss-Prot
  NTF2 UniProtKB/Swiss-Prot
  NTF2-like_dom_sf UniProtKB/Swiss-Prot
  Nuclear_transport_factor_2_euk UniProtKB/Swiss-Prot
  Nucleotide-bd_a/b_plait_sf UniProtKB/Swiss-Prot
  NXF_fam UniProtKB/Swiss-Prot
  RBD_domain_sf UniProtKB/Swiss-Prot
  TAP_C_dom UniProtKB/Swiss-Prot
  Tap_RNA-bd UniProtKB/Swiss-Prot
  UBA-like_sf UniProtKB/Swiss-Prot
KEGG Report rno:59087 UniProtKB/Swiss-Prot
NCBI Gene 59087 ENTREZGENE
PANTHER NUCLEAR RNA EXPORT FACTOR 1 UniProtKB/Swiss-Prot
  PTHR10662 UniProtKB/Swiss-Prot
Pfam NXF_NTF2 UniProtKB/Swiss-Prot
  Tap-RNA_bind UniProtKB/Swiss-Prot
  TAP_C UniProtKB/Swiss-Prot
PhenoGen Nxf1 PhenoGen
PROSITE LRR UniProtKB/Swiss-Prot
  NTF2_DOMAIN UniProtKB/Swiss-Prot
  TAP_C UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000019069 RatGTEx
SMART TAP_C UniProtKB/Swiss-Prot
Superfamily-SCOP L domain-like UniProtKB/Swiss-Prot
  SSF46934 UniProtKB/Swiss-Prot
  SSF54427 UniProtKB/Swiss-Prot
  SSF54928 UniProtKB/Swiss-Prot
TIGR TC205107
UniProt A0A8I5ZVD9_RAT UniProtKB/TrEMBL
  F1MA52 ENTREZGENE, UniProtKB/TrEMBL
  NXF1_RAT UniProtKB/Swiss-Prot, ENTREZGENE
1 to 39 of 39 rows


Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2005-07-14 Nxf1  nuclear RNA export factor 1      Symbol and Name status set to provisional 70820 PROVISIONAL
2005-03-29   nuclear RNA export factor 1  Nxf1  nuclear RNA export factor 1 homolog (S. cerevisiae)   Name updated 1299863 APPROVED
2002-06-10 Nxf1  nuclear RNA export factor 1 homolog (S. cerevisiae)       Name updated 70584 APPROVED

Note Type Note Reference