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RIBOSOME BIOGENESIS PATHWAY (PW:0001066)

View Ontology Report

Description

The ribosome is involved in the final stage of gene expression thereby the genetic information is decoded into the protein polypeptide chain. In all organisms the ribosome is built of two subunits, each with distinct functions. The small eukaryotic 40S subunit (30S in prokaryotes) is the decoder that reads the mRNA while the large 60S subunit (50S in prokaryotes) carries out the catalytic peptidyl transferase reaction. The small 40s subunit is composed of one rRNA and 33 ribosomal proteins (RPS)

Pathway Diagram:

Elsevier Inc. Eif6 5S rRNA partners ITS1 cleavage/processing ---> pre-60S subunit box C/D 40S subunit ---- 60S subunit 80S ribosome translation pathway 60S subunit start codon scanning translation initiation pathway Mdn1 Gnl2 40S subunit ---> start codon scanning ribosomal proteins, large subunit ---> 60S subunit pre-60S subunit <--> 60S subunit pre-40S subunit ---> 40S subunit RNA helicases in ribosome biogenesis ribosomal proteins, large subunit large subunit maturation ribosomal proteins, small subunit small subnit maturation pre-60S subunit pre-40S subunit ITS1 cleavage/processing 5'-ETS cleavage/processing box H/ACA Nup88 Nup214 GTP Prkcb ---> Eif6 Prkcb ---| Eif6 pre-60S subunit ---- Xpo5 Nup214 ---- Xpo1 Nup214 ---- Nup88 Eri1 ribosomal proteins, small subunit ---> 40S subunit Gnl2 ---| Nmd3 ribosomal proteins, small subunit ---> pre-40S subunit ribosomal proteins, large subunit ---> pre-60S subunit box H/ACA ---> pre-60S subunit box C/D ---> pre-40S subunit box C/D ---> pre-60S subunit box H/ACA ---> pre-40S subunit 28S 5.8S ITS1 cleavage/processing ---> pre-40S subunit 5'-ETS cleavage/processing ---> pre-40S subunit RNA helicases in ribosome biogenesis ---> pre-40S subunit RNA helicases in ribosome biogenesis ---> pre-60S subunit Eri1 ---> 60S subunit Nob1 Nob1 ---> 40S subunit Prkcb RNA polymerase I transcription pathway RNA polymerase III transcription pathway Gnb2l1 Gnb2l1 ---- Prkcb 40S subunit ---- Gnb2l1 60S subunit ---- Eif6 5S ---> pre-60S subunit 5S 5S ---- 5S rRNA partners Ran Xpo5 Nmd3 ---- Xpo1 GTP ---- Ran Nmd3 5.8S ---> large subunit maturation 28S ---> large subunit maturation 18S 40S subunit Xpo1 Nmd3 ---- pre-60S subunit Ltv1 ---- Xpo1 Ltv1 small subnit maturation ---> 40S subunit large subunit maturation ---> 60S subunit 18S ---> small subnit maturation Gnl2 ---- pre-60S subunit Mdn1 ---| Gnl2 Eif6 ---| 80S ribosome
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Genes in Pathway:


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ribosome biogenesis pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G 1700009N14Rikl RIKEN cDNA 1700009N14 gene like IEA KEGG rno:03008 NCBI chr 5:54,456,005...54,457,381
Ensembl chr 5:54,455,893...54,457,677
JBrowse link
G Afg2a AFG2 AAA ATPase homolog A IEA KEGG rno:03008 NCBI chr 2:120,306,417...120,497,707
Ensembl chr 2:120,306,412...120,497,705
JBrowse link
G Bms1 BMS1 ribosome biogenesis factor IEA
ISO
KEGG
RGD
PMID:24550520 rno:03008, RGD:9999445 NCBI chr 4:151,558,163...151,595,187
Ensembl chr 4:151,558,163...151,595,127
JBrowse link
G Bop1 BOP1 ribosomal biogenesis factor ISO RGD PMID:25346433 PMID:23439679 RGD:9999448, RGD:9999449 NCBI chr 7:108,172,062...108,195,875
Ensembl chr 7:108,172,066...108,195,931
JBrowse link
G Bysl bystin-like ISO RGD PMID:25346433 PMID:23439679 PMID:24424021 RGD:9999448, RGD:9999449, RGD:10002751 NCBI chr 9:13,382,806...13,392,557
Ensembl chr 9:13,382,557...13,394,339
JBrowse link
G C1d C1D nuclear receptor corepressor ISO RGD PMID:25346433 RGD:9999448 NCBI chr14:91,660,951...91,673,177
Ensembl chr14:91,660,989...91,672,852
JBrowse link
G Csnk1d casein kinase 1, delta ISO RGD PMID:24424021 RGD:10002751 NCBI chr10:106,221,992...106,256,620
Ensembl chr10:106,221,992...106,256,614
JBrowse link
G Csnk1e casein kinase 1, epsilon ISO RGD PMID:24424021 RGD:10002751 NCBI chr 7:110,983,322...111,006,926
Ensembl chr 7:110,983,318...111,006,794
JBrowse link
G Csnk2a1 casein kinase 2 alpha 1 IEA KEGG rno:03008 NCBI chr 3:140,709,984...140,756,757
Ensembl chr 3:140,709,991...140,756,696
JBrowse link
G Csnk2a2 casein kinase 2 alpha 2 IEA KEGG rno:03008 NCBI chr19:9,556,443...9,596,080
Ensembl chr19:9,556,260...9,596,080
JBrowse link
G Csnk2b casein kinase 2 beta IEA KEGG rno:03008 NCBI chr20:3,700,363...3,705,331
Ensembl chr20:3,698,733...3,707,133
JBrowse link
G Ddx10 DEAD-box helicase 10 ISO RGD PMID:22922795 RGD:10002738 NCBI chr 8:53,488,656...53,643,373
Ensembl chr 8:53,488,656...53,643,373
JBrowse link
G Ddx18 DEAD-box helicase 18 ISO RGD PMID:22922795 RGD:10002738 NCBI chr13:32,729,697...32,743,161
Ensembl chr13:32,729,700...32,743,161
JBrowse link
G Ddx24 DEAD-box helicase 24 ISO RGD PMID:22922795 RGD:10002738 NCBI chr 6:122,564,767...122,582,032
Ensembl chr 6:122,564,767...122,581,927
JBrowse link
G Ddx56 DEAD-box helicase 56 ISO RGD PMID:22922795 RGD:10002738 NCBI chr14:81,112,008...81,122,331
Ensembl chr14:81,112,012...81,122,333
JBrowse link
G Dhx15 DEAH-box helicase 15 ISO RGD PMID:22922795 RGD:10002738 NCBI chr14:58,787,147...58,825,083
Ensembl chr14:58,787,127...58,825,088
JBrowse link
G Dhx37 DEAH-box helicase 37 ISO RGD PMID:22922795 RGD:10002738 NCBI chr12:31,194,782...31,214,890
Ensembl chr12:31,194,859...31,216,802
JBrowse link
G Dis3 DIS3 homolog, exosome endoribonuclease and 3'-5' exoribonuclease ISO RGD PMID:25346433 RGD:9999448 NCBI chr15:75,820,040...75,850,450
Ensembl chr15:75,823,436...75,850,642
JBrowse link
G Dkc1 dyskerin pseudouridine synthase 1 IEA
ISO
KEGG
RGD
PMID:22065625 rno:03008, RGD:9999451
G Efl1 elongation factor like GTPase 1 IEA KEGG rno:03008 NCBI chr 1:136,638,527...136,763,518
Ensembl chr 1:136,638,527...136,763,518
JBrowse link
G Eif6 eukaryotic translation initiation factor 6 IEA
ISO
KEGG
RGD
PMID:19373251 rno:03008, RGD:10002774 NCBI chr 3:144,325,038...144,331,396
Ensembl chr 3:144,325,036...144,331,401
JBrowse link
G Emg1 EMG1 N1-specific pseudouridine methyltransferase IEA KEGG rno:03008 NCBI chr 4:157,509,258...157,517,540
Ensembl chr 4:157,509,277...157,517,540
JBrowse link
G Eri1 exoribonuclease 1 ISO RGD PMID:25346433 RGD:9999448 NCBI chr16:56,724,101...56,744,228
Ensembl chr16:56,724,115...56,744,226
JBrowse link
G Exosc10 exosome component 10 ISO RGD PMID:24550520 RGD:9999445 NCBI chr 5:158,995,313...159,018,940
Ensembl chr 5:158,995,313...159,018,940
JBrowse link
G Exosc5 exosome component 5 ISO RGD PMID:24550520 RGD:9999445 NCBI chr 1:81,168,128...81,177,266
Ensembl chr 1:81,166,023...81,177,265
JBrowse link
G Fau FAU ubiquitin like and ribosomal protein S30 fusion ISO RGD PMID:20819938 PMID:23636399 RGD:10002730, RGD:10002762 NCBI chr 1:203,350,226...203,351,741
Ensembl chr 1:203,350,189...203,351,742
JBrowse link
G Fbl fibrillarin IEA
ISO
KEGG
RGD
PMID:22065625 rno:03008, RGD:9999451 NCBI chr 1:83,469,832...83,478,932
Ensembl chr 1:83,469,832...83,478,932
JBrowse link
G Fbll1 fibrillarin-like 1 IEA KEGG rno:03008 NCBI chr10:20,258,656...20,260,299
Ensembl chr10:20,258,656...20,260,299
JBrowse link
G Fcf1 Fcf1 rRNA-processing protein ISO RGD PMID:24550520 RGD:9999445 NCBI chr 6:104,617,780...104,629,643
Ensembl chr 6:104,617,770...104,629,643
JBrowse link
G Gar1 GAR1 ribonucleoprotein IEA
ISO
KEGG
RGD
PMID:22065625 rno:03008, RGD:9999451 NCBI chr 2:218,375,231...218,382,509
Ensembl chr 2:218,375,353...218,382,524
JBrowse link
G Gnl2 G protein nucleolar 2 IEA
ISO
KEGG
RGD
PMID:24240281 rno:03008, RGD:10002740 NCBI chr 5:137,293,141...137,318,528
Ensembl chr 5:137,293,081...137,318,526
JBrowse link
G Gnl3 G protein nucleolar 3 IEA KEGG rno:03008 NCBI chr16:6,207,402...6,213,491
Ensembl chr16:6,207,402...6,213,392
JBrowse link
G Gnl3l G protein nucleolar 3 like IEA KEGG rno:03008 NCBI chr  X:19,961,277...19,994,454
Ensembl chr  X:19,958,603...19,994,508
JBrowse link
G Gtpbp4 GTP binding protein 4 IEA KEGG rno:03008 NCBI chr17:61,308,033...61,328,184
Ensembl chr17:61,308,014...61,418,009
JBrowse link
G Heatr1 HEAT repeat containing 1 IEA KEGG rno:03008 NCBI chr17:58,053,288...58,093,895
Ensembl chr17:58,051,700...58,093,948
JBrowse link
G Imp3 IMP U3 small nucleolar ribonucleoprotein 3 IEA
ISO
KEGG
RGD
PMID:24550520 rno:03008, RGD:9999445 NCBI chr 8:57,339,528...57,340,416
Ensembl chr 8:57,339,496...57,340,414
JBrowse link
G Imp4 IMP U3 small nucleolar ribonucleoprotein 4 IEA
ISO
KEGG
RGD
PMID:24550520 rno:03008, RGD:9999445 NCBI chr 9:36,654,127...36,659,265
Ensembl chr 9:36,654,401...36,660,075
JBrowse link
G Lsg1 large 60S subunit nuclear export GTPase 1 IEA KEGG rno:03008 NCBI chr11:70,132,919...70,168,526
Ensembl chr11:70,143,847...70,168,518
JBrowse link
G Ltv1 LTV1 ribosome biogenesis factor ISO RGD PMID:20137954 PMID:24424021 RGD:10002748, RGD:10002751 NCBI chr 1:7,565,673...7,578,398
Ensembl chr 1:7,565,669...7,578,563
JBrowse link
G Mdn1 midasin AAA ATPase 1 IEA
ISO
KEGG
RGD
PMID:21763358 rno:03008, RGD:10002739 NCBI chr 5:47,055,435...47,190,426
Ensembl chr 5:47,055,447...47,186,332
JBrowse link
G Mphosph10 M-phase phosphoprotein 10 IEA
ISO
KEGG
RGD
PMID:24550520 rno:03008, RGD:9999445 NCBI chr 1:117,948,134...117,964,149
Ensembl chr 1:117,948,134...117,964,149
JBrowse link
G Mtrex Mtr4 exosome RNA helicase ISO RGD PMID:24550520 RGD:9999445 NCBI chr 2:44,500,326...44,560,624
Ensembl chr 2:44,461,444...44,560,627
JBrowse link
G Nhp2 NHP2 ribonucleoprotein IEA
ISO
KEGG
RGD
PMID:22065625 rno:03008, RGD:9999451 NCBI chr10:35,877,057...35,880,399
Ensembl chr10:35,877,054...35,882,545
JBrowse link
G Nmd3 NMD3 ribosome export adaptor IEA
ISO
KEGG
RGD
PMID:17509569 PMID:20137954 rno:03008, RGD:10002749, RGD:10002748 NCBI chr 2:154,012,973...154,038,466
Ensembl chr 2:154,013,020...154,039,259
JBrowse link
G Nob1 NIN1 (RPN12) binding protein 1 homolog IEA
ISO
KEGG
RGD
PMID:23439679 PMID:25346433 PMID:24424021 rno:03008, RGD:9999449, RGD:9999448, RGD:10002751 NCBI chr19:35,322,803...35,335,354
Ensembl chr19:35,322,669...35,346,815
JBrowse link
G Nol12 nucleolar protein 12 ISO RGD PMID:25346433 PMID:23439679 RGD:9999448, RGD:9999449 NCBI chr 7:110,493,294...110,498,908
Ensembl chr 7:110,493,246...110,498,907
JBrowse link
G Nop10 NOP10 ribonucleoprotein IEA
ISO
KEGG
RGD
PMID:22065625 rno:03008, RGD:9999451 NCBI chr 3:99,066,857...99,067,942
Ensembl chr 3:99,066,857...99,067,942
JBrowse link
G Nop56 NOP56 ribonucleoprotein IEA
ISO
KEGG
RGD
PMID:22065625 rno:03008, RGD:9999451 NCBI chr 3:117,476,963...117,481,847
Ensembl chr 3:117,477,053...117,481,841
JBrowse link
G Nop58 NOP58 ribonucleoprotein IEA
ISO
KEGG
RGD
PMID:22065625 rno:03008, RGD:9999451 NCBI chr 9:61,120,939...61,144,810
Ensembl chr 9:61,120,929...61,144,810
JBrowse link
G Nup214 nucleoporin 214 ISO RGD PMID:17509569 RGD:10002749 NCBI chr 3:15,255,111...15,340,568
Ensembl chr 3:15,255,119...15,340,568
JBrowse link
G Nup88 nucleoporin 88 ISO RGD PMID:17509569 RGD:10002749 NCBI chr10:55,667,903...55,692,249
Ensembl chr10:55,667,906...55,692,257
JBrowse link
G Nvl nuclear VCP-like IEA KEGG rno:03008 NCBI chr13:92,851,023...92,906,749
Ensembl chr13:92,853,650...92,906,049
JBrowse link
G Nxf1 nuclear RNA export factor 1 IEA KEGG rno:03008 NCBI chr 1:205,655,442...205,668,637
Ensembl chr 1:205,655,375...205,668,636
JBrowse link
G Nxf3 nuclear RNA export factor 3 IEA KEGG rno:03008 NCBI chr  X:99,025,901...99,050,409
Ensembl chr  X:99,025,901...99,039,261
JBrowse link
G Nxf7 nuclear RNA export factor 7 IEA KEGG rno:03008 NCBI chr  X:98,535,374...98,552,562
Ensembl chr  X:98,535,375...98,552,526
JBrowse link
G Nxt1 nuclear transport factor 2-like export factor 1 IEA KEGG rno:03008 NCBI chr 3:136,108,975...136,111,897
Ensembl chr 3:136,108,862...136,111,907
JBrowse link
G Nxt2 nuclear transport factor 2-like export factor 2 IEA KEGG rno:03008 NCBI chr  X:105,855,616...105,862,902
Ensembl chr  X:105,855,608...105,862,899
JBrowse link
G Pals2 protein associated with LIN7 2, MAGUK p55 family member ISO RGD PMID:25346433 RGD:9999448 NCBI chr 4:79,173,488...79,257,542
Ensembl chr 4:79,124,806...79,254,140
JBrowse link
G Pdcd11 programmed cell death 11 ISO RGD PMID:23439679 RGD:9999449 NCBI chr 1:245,980,840...246,021,999
Ensembl chr 1:245,980,880...246,021,999
JBrowse link
G Pes1 pescadillo ribosomal biogenesis factor 1 ISO RGD PMID:25346433 RGD:9999448 NCBI chr14:78,850,754...78,867,134
Ensembl chr14:78,850,709...78,867,134
JBrowse link
G Pno1 partner of NOB1 homolog ISO RGD PMID:24424021 RGD:10002751 NCBI chr14:91,609,711...91,618,280
Ensembl chr14:91,609,233...91,618,324
JBrowse link
G Pop1 POP1 homolog, ribonuclease P/MRP subunit IEA KEGG rno:03008 NCBI chr 7:65,705,348...65,733,143
Ensembl chr 7:65,705,368...65,733,141
JBrowse link
G Pop4 POP4 homolog, ribonuclease P/MRP subunit IEA KEGG rno:03008 NCBI chr 1:90,960,026...90,968,360
Ensembl chr 1:90,960,022...90,968,443
JBrowse link
G Pop5 POP5 homolog, ribonuclease P/MRP subunit IEA KEGG rno:03008 NCBI chr12:41,376,755...41,384,882
Ensembl chr12:41,376,755...41,381,336
JBrowse link
G Pop7 POP7 homolog, ribonuclease P/MRP subunit IEA KEGG rno:03008 NCBI chr12:19,189,384...19,190,425
Ensembl chr12:19,189,138...19,190,674
JBrowse link
G Prkcb protein kinase C, beta ISO RGD PMID:19373251 RGD:10002774 NCBI chr 1:176,832,173...177,163,539
Ensembl chr 1:176,832,226...177,163,536
JBrowse link
G Pwp2 PWP2, small subunit processome component IEA KEGG rno:03008 NCBI chr20:10,499,332...10,512,965
Ensembl chr20:10,499,363...10,513,640
JBrowse link
G Rack1 receptor for activated C kinase 1 ISO RGD PMID:19373251 RGD:10002774 NCBI chr10:33,169,415...33,174,896
Ensembl chr10:33,169,169...33,174,975
JBrowse link
G Ran RAN, member RAS oncogene family IEA
ISO
KEGG
RGD
PMID:17509569 rno:03008, RGD:10002749 NCBI chr12:27,674,049...27,678,598
Ensembl chr12:27,674,050...27,678,276
JBrowse link
G Rasl2-9 RAS-like, family 2, locus 9 IEA KEGG rno:03008 NCBI chr 1:68,720,879...68,734,930
Ensembl chr 1:68,720,879...68,722,057
JBrowse link
G Rbm28 RNA binding motif protein 28 IEA
ISO
KEGG
RGD
PMID:23439679 rno:03008, RGD:9999449 NCBI chr 4:57,722,946...57,761,935
Ensembl chr 4:57,722,223...57,761,653
JBrowse link
G Rcl1 RNA terminal phosphate cyclase-like 1 IEA
ISO
KEGG
RGD
PMID:24550520 rno:03008, RGD:9999445 NCBI chr 1:226,824,561...226,869,046
Ensembl chr 1:226,824,534...226,902,315
JBrowse link
G Rexo1 RNA exonuclease 1 homolog IEA KEGG rno:03008 NCBI chr 7:9,154,050...9,174,035
Ensembl chr 7:9,154,061...9,173,454
JBrowse link
G Rexo1l1-ps1 REX1, RNA exonuclease 1 homolog-like 1, pseudogene 1 IEA KEGG rno:03008 NCBI chr 2:138,834,049...138,838,838
Ensembl chr 2:138,834,559...138,837,083
JBrowse link
G Rexo2 RNA exonuclease 2 IEA KEGG rno:03008 NCBI chr 8:48,811,900...48,823,622
Ensembl chr 8:48,811,900...48,823,622
JBrowse link
G Rexo5 RNA exonuclease 5 IEA KEGG rno:03008 NCBI chr 1:174,168,633...174,264,526
Ensembl chr 1:174,168,694...174,241,486
JBrowse link
G Riok1 RIO kinase 1 IEA
ISO
KEGG
RGD
PMID:24424021 rno:03008, RGD:10002751 NCBI chr17:26,767,440...26,789,900
Ensembl chr17:26,766,947...26,789,900
JBrowse link
G Riok2 RIO kinase 2 IEA
ISO
KEGG
RGD
PMID:24424021 rno:03008, RGD:10002751 NCBI chr 1:58,103,132...58,119,397
Ensembl chr 1:58,103,084...58,120,512
JBrowse link
G Riok3 RIO kinase 3 ISO RGD PMID:24424021 RGD:10002751 NCBI chr18:3,327,776...3,353,350
Ensembl chr18:3,327,776...3,353,343
JBrowse link
G Rpl10 ribosomal protein L10 ISO RGD PMID:23636399 RGD:10002762 NCBI chr  X:152,054,562...152,056,769
Ensembl chr  X:152,054,452...152,056,761
JBrowse link
G Rpl10a ribosomal protein L10A ISO RGD PMID:23636399 RGD:10002762 NCBI chr20:6,388,800...6,391,358
Ensembl chr20:6,385,823...6,391,357
JBrowse link
G Rpl11 ribosomal protein L11 ISO RGD PMID:23636399 RGD:10002762 NCBI chr 5:148,274,060...148,277,708
Ensembl chr 5:148,274,069...148,277,599
JBrowse link
G Rpl12 ribosomal protein L12 ISO RGD PMID:23636399 RGD:10002762 NCBI chr 3:16,264,269...16,266,645
Ensembl chr 3:16,264,251...16,266,642
JBrowse link
G Rpl13 ribosomal protein L13 ISO RGD PMID:23636399 RGD:10002762 NCBI chr19:51,153,990...51,156,541
Ensembl chr19:51,153,924...51,163,014
JBrowse link
G Rpl13a ribosomal protein L13A ISO RGD PMID:23636399 RGD:10002762 NCBI chr 1:95,609,374...95,612,557
Ensembl chr 1:95,609,370...95,620,463
JBrowse link
G Rpl14 ribosomal protein L14 ISO RGD PMID:23636399 RGD:10002762 NCBI chr 8:120,286,035...120,289,160
Ensembl chr 8:120,284,645...120,289,064
JBrowse link
G Rpl15 ribosomal protein L15 ISO RGD PMID:25346433 PMID:23636399 RGD:9999448, RGD:10002762 NCBI chr15:7,503,883...7,507,166
Ensembl chr15:7,503,883...7,507,165
JBrowse link
G Rpl17 ribosomal protein L17 ISO RGD PMID:23636399 RGD:10002762 NCBI chr18:68,581,141...68,584,253
Ensembl chr18:68,581,098...68,584,253
JBrowse link
G Rpl18 ribosomal protein L18 ISO RGD PMID:23636399 RGD:10002762 NCBI chr 1:96,188,811...96,191,452
Ensembl chr 1:96,188,112...96,191,452
JBrowse link
G Rpl18a ribosomal protein L18A ISO RGD PMID:23636399 RGD:10002762 NCBI chr16:18,542,555...18,544,578
Ensembl chr16:18,542,566...18,545,546
JBrowse link
G Rpl19 ribosomal protein L19 ISO RGD PMID:23636399 RGD:10002762 NCBI chr10:83,022,503...83,026,030
Ensembl chr10:83,019,257...83,052,112
JBrowse link
G Rpl21 ribosomal protein L21 ISO RGD PMID:23636399 RGD:10002762 NCBI chr12:8,268,641...8,272,278
Ensembl chr12:8,267,196...8,272,281
Ensembl chr 3:8,267,196...8,272,281
Ensembl chr13:8,267,196...8,272,281
JBrowse link
G Rpl22 ribosomal protein L22 ISO RGD PMID:23636399 RGD:10002762 NCBI chr 5:162,835,241...162,843,394
Ensembl chr 5:162,833,740...162,843,368
Ensembl chr 7:162,833,740...162,843,368
Ensembl chr 4:162,833,740...162,843,368
JBrowse link
G Rpl23 ribosomal protein L23 ISO RGD PMID:23636399 RGD:10002762 NCBI chr10:82,771,878...82,775,840
Ensembl chr10:82,771,538...82,775,870
JBrowse link
G Rpl23a ribosomal protein L23A ISO RGD PMID:23636399 RGD:10002762 NCBI chr10:63,076,660...63,079,346
Ensembl chr10:63,076,066...63,079,346
JBrowse link
G Rpl24 ribosomal protein L24 ISO RGD PMID:23636399 RGD:10002762 NCBI chr11:44,653,937...44,659,346
Ensembl chr11:44,653,937...44,659,370
JBrowse link
G Rpl26 ribosomal protein L26 ISO RGD PMID:25346433 PMID:23636399 RGD:9999448, RGD:10002762 NCBI chr10:53,610,836...53,613,966
Ensembl chr10:53,610,421...53,613,966
JBrowse link
G Rpl27 ribosomal protein L27 ISO RGD PMID:23636399 RGD:10002762 NCBI chr10:86,375,511...86,379,210
Ensembl chr10:86,375,454...86,379,193
JBrowse link
G Rpl27a ribosomal protein L27A ISO RGD PMID:23636399 RGD:10002762 NCBI chr 1:163,539,732...163,542,771 JBrowse link
G Rpl28 ribosomal protein L28 ISO RGD PMID:23636399 RGD:10002762 NCBI chr 1:69,052,148...69,054,735
Ensembl chr 1:69,053,203...69,055,032
JBrowse link
G Rpl29 ribosomal protein L29 ISO RGD PMID:23636399 RGD:10002762 NCBI chr 8:107,068,929...107,070,963
Ensembl chr 8:107,068,480...107,070,914
JBrowse link
G Rpl3 ribosomal protein L3 ISO RGD PMID:23636399 RGD:10002762 NCBI chr 7:111,622,255...111,627,640
Ensembl chr 7:111,621,610...111,636,468
JBrowse link
G Rpl30 ribosomal protein L30 ISO RGD PMID:23636399 RGD:10002762 NCBI chr 7:65,648,266...65,651,401
Ensembl chr 7:65,645,991...65,651,363
Ensembl chr10:65,645,991...65,651,363
Ensembl chr10:65,645,991...65,651,363
JBrowse link
G Rpl31 ribosomal protein L31 ISO RGD PMID:23636399 RGD:10002762 NCBI chr 9:41,647,397...41,651,441
Ensembl chr 9:41,647,426...41,662,129
JBrowse link
G Rpl32 ribosomal protein L32 ISO RGD PMID:23636399 RGD:10002762 NCBI chr 4:148,864,048...148,867,612
Ensembl chr 4:148,864,044...148,867,612
JBrowse link
G Rpl34 ribosomal protein L34 ISO RGD PMID:23636399 RGD:10002762 NCBI chr 2:219,284,373...219,288,108
Ensembl chr 2:219,284,382...219,288,111
JBrowse link
G Rpl35 ribosomal protein L35 ISO RGD PMID:23636399 RGD:10002762 NCBI chr 3:22,753,255...22,756,217
Ensembl chr 3:22,753,253...22,756,243
JBrowse link
G Rpl35a ribosomal protein L35A ISO RGD PMID:23636399 RGD:10002762 NCBI chr11:67,726,031...67,729,953
Ensembl chr11:67,726,032...67,729,942
Ensembl chr 5:67,726,032...67,729,942
JBrowse link
G Rpl36 ribosomal protein L36 ISO RGD PMID:23636399 RGD:10002762 NCBI chr 9:1,441,986...1,447,397
Ensembl chr 6:98,809,534...98,809,897
JBrowse link
G Rpl36a ribosomal protein L36A ISO RGD PMID:23636399 RGD:10002762 NCBI chr  X:97,766,179...97,768,892
Ensembl chr  X:97,766,179...97,768,892
JBrowse link
G Rpl37 ribosomal protein L37 ISO RGD PMID:23636399 RGD:10002762 NCBI chr 2:54,215,469...54,217,429
Ensembl chr 2:54,215,469...54,217,442
JBrowse link
G Rpl37a ribosomal protein L37A ISO RGD PMID:23636399 RGD:10002762 NCBI chr 9:74,298,843...74,300,926 JBrowse link
G Rpl37l1 ribosomal protein L37-like 1 ISO RGD PMID:23636399 RGD:10002762 NCBI chr10:61,033,799...61,034,157
Ensembl chr10:61,033,797...61,034,168
Ensembl chr 9:61,033,797...61,034,168
JBrowse link
G Rpl38 ribosomal protein L38 ISO RGD PMID:23636399 RGD:10002762 NCBI chr10:99,701,330...99,705,004
Ensembl chr10:99,701,362...99,705,004
Ensembl chr14:99,701,362...99,705,004
Ensembl chr 3:99,701,362...99,705,004
Ensembl chr 2:99,701,362...99,705,004
Ensembl chr16:99,701,362...99,705,004
JBrowse link
G Rpl39 ribosomal protein L39 ISO RGD PMID:23636399 RGD:10002762 NCBI chr  X:116,327,216...116,330,211
Ensembl chr18:6,326,330...6,326,692
Ensembl chr  X:6,326,330...6,326,692
JBrowse link
G Rpl4 ribosomal protein L4 ISO RGD PMID:23636399 RGD:10002762 NCBI chr 8:64,671,177...64,676,301
Ensembl chr 8:64,671,160...64,676,306
JBrowse link
G Rpl5 ribosomal protein L5 ISO RGD PMID:23636399 RGD:10002762 NCBI chr14:1,843,856...1,850,301
Ensembl chr14:1,843,770...1,850,290
JBrowse link
G Rpl6 ribosomal protein L6 ISO RGD PMID:23636399 RGD:10002762 NCBI chr12:35,347,493...35,352,011
Ensembl chr12:35,347,497...35,351,921
JBrowse link
G Rpl7 ribosomal protein L7 ISO RGD PMID:23636399 RGD:10002762 NCBI chr 5:3,217,184...3,220,192 JBrowse link
G Rpl7a ribosomal protein L7A ISO RGD PMID:23636399 RGD:10002762 NCBI chr 3:10,239,026...10,241,703
Ensembl chr 3:10,239,001...10,241,716
JBrowse link
G Rpl8 ribosomal protein L8 ISO RGD PMID:23636399 RGD:10002762 NCBI chr 7:108,626,194...108,628,485
Ensembl chr 7:108,622,324...108,628,482
Ensembl chr 3:108,622,324...108,628,482
JBrowse link
G Rpl9 ribosomal protein L9 ISO RGD PMID:23636399 RGD:10002762 NCBI chr14:42,893,945...42,897,140
Ensembl chr14:42,893,942...42,897,136
Ensembl chr 3:42,893,942...42,897,136
JBrowse link
G Rplp0 ribosomal protein lateral stalk subunit P0 ISO RGD PMID:23636399 RGD:10002762 NCBI chr12:41,054,363...41,057,632
Ensembl chr12:41,054,179...41,057,632
JBrowse link
G Rplp1 ribosomal protein lateral stalk subunit P1 ISO RGD PMID:23636399 RGD:10002762 NCBI chr 8:62,394,008...62,395,341
Ensembl chr 8:62,393,177...62,395,339
JBrowse link
G Rplp2 ribosomal protein lateral stalk subunit P2 ISO RGD PMID:23636399 RGD:10002762 NCBI chr 1:196,546,086...196,548,636
Ensembl chr 1:196,546,352...196,548,645
JBrowse link
G Rpp25 ribonuclease P and MRP subunit p25 IEA KEGG rno:03008 NCBI chr 8:57,907,352...57,908,732
Ensembl chr 8:57,907,352...57,908,732
JBrowse link
G Rpp30 ribonuclease P/MRP subunit p30 IEA KEGG rno:03008 NCBI chr 1:233,786,048...233,808,958
Ensembl chr 1:233,786,099...233,808,952
JBrowse link
G Rpp38 ribonuclease P/MRP subunit p38 IEA KEGG rno:03008 NCBI chr17:74,914,066...74,917,742
Ensembl chr17:74,908,932...74,927,431
JBrowse link
G Rpp40 ribonuclease P/MRP subunit p40 IEA KEGG rno:03008 NCBI chr17:28,947,752...28,956,788
Ensembl chr17:28,947,734...28,956,788
JBrowse link
G Rps10 ribosomal protein S10 ISO RGD PMID:20819938 PMID:23636399 RGD:10002730, RGD:10002762 NCBI chr20:5,694,313...5,698,922
Ensembl chr20:5,694,313...5,699,044
Ensembl chr 6:5,694,313...5,699,044
JBrowse link
G Rps11 ribosomal protein S11 ISO RGD PMID:20819938 PMID:23636399 RGD:10002730, RGD:10002762 NCBI chr 1:95,605,690...95,607,798
Ensembl chr 1:95,605,692...95,607,874
JBrowse link
G Rps12 ribosomal protein S12 ISO RGD PMID:20819938 PMID:23636399 RGD:10002730, RGD:10002762 NCBI chr 1:21,680,854...21,683,010
Ensembl chr 1:21,680,852...21,683,014
JBrowse link
G Rps13 ribosomal protein S13 ISO RGD PMID:20819938 PMID:23636399 RGD:10002730, RGD:10002762 NCBI chr 1:170,572,925...170,575,355
Ensembl chr 1:170,572,921...170,575,355
Ensembl chr 3:170,572,921...170,575,355
JBrowse link
G Rps14 ribosomal protein S14 ISO RGD PMID:20819938 PMID:23636399 RGD:10002730, RGD:10002762 NCBI chr18:54,227,854...54,232,638
Ensembl chr18:54,227,854...54,233,166
JBrowse link
G Rps15 ribosomal protein S15 ISO RGD PMID:20819938 PMID:23636399 RGD:10002730, RGD:10002762 NCBI chr 7:9,416,003...9,417,442
Ensembl chr 7:9,416,004...9,417,450
JBrowse link
G Rps15a ribosomal protein S15a ISO RGD PMID:20819938 PMID:23636399 RGD:10002730, RGD:10002762 NCBI chr 1:172,420,151...172,427,021
Ensembl chr 1:172,419,761...172,426,995
JBrowse link
G Rps16 ribosomal protein S16 ISO RGD PMID:20819938 PMID:23636399 RGD:10002730, RGD:10002762 NCBI chr 1:83,643,066...83,646,056
Ensembl chr 1:83,643,130...83,646,206
JBrowse link
G Rps17 ribosomal protein S17 ISO RGD PMID:20819938 PMID:23636399 RGD:10002730 RGD:10002762 NCBI chr 1:135,295,920...135,298,506
Ensembl chr 1:135,295,919...135,298,535
Ensembl chr 8:135,295,919...135,298,535
JBrowse link
G Rps18 ribosomal protein S18 ISO RGD PMID:25346433 PMID:20819938 PMID:23636399 RGD:9999448, RGD:10002730, RGD:10002762 NCBI chr20:4,931,427...4,935,538
Ensembl chr10:101,204,500...101,205,146
Ensembl chr20:101,204,500...101,205,146
JBrowse link
G Rps19 ribosomal protein S19 ISO RGD PMID:25346433 PMID:23439679 PMID:20819938 PMID:23636399 RGD:9999448, RGD:9999449, RGD:10002730, RGD:10002762 NCBI chr 1:80,480,718...80,486,511
Ensembl chr 1:80,480,951...80,486,508
JBrowse link
G Rps2 ribosomal protein S2 ISO RGD PMID:20819938 PMID:23636399 RGD:10002730, RGD:10002762 NCBI chr10:13,747,316...13,749,165
Ensembl chr10:13,747,301...13,749,163
JBrowse link
G Rps20 ribosomal protein S20 ISO RGD PMID:20819938 PMID:23636399 RGD:10002730, RGD:10002762 NCBI chr 5:16,819,095...16,820,476
Ensembl chr 5:16,819,304...16,820,475
Ensembl chr 9:16,819,304...16,820,475
Ensembl chr 3:16,819,304...16,820,475
JBrowse link
G Rps21 ribosomal protein S21 ISO RGD PMID:20819938 PMID:23636399 RGD:10002730, RGD:10002762 NCBI chr 3:167,346,437...167,347,459
Ensembl chr 3:167,346,201...167,347,470
JBrowse link
G Rps21-ps1 ribosomal protein S21, pseudogene 1 ISO RGD PMID:20819938 PMID:23636399 RGD:10002730 RGD:10002762 NCBI chr 5:153,387,133...153,387,476
Ensembl chr 5:153,387,176...153,387,427
JBrowse link
G Rps23 ribosomal protein S23 ISO RGD PMID:20819938 PMID:23636399 RGD:10002730, RGD:10002762 NCBI chr 2:22,079,339...22,080,909
Ensembl chr 2:22,079,302...22,080,918
JBrowse link
G Rps24 ribosomal protein S24 ISO RGD PMID:20819938 PMID:23636399 RGD:10002730, RGD:10002762 NCBI chr16:89,538...94,267
Ensembl chr16:89,604...94,279
JBrowse link
G Rps25 ribosomal protein s25 ISO RGD PMID:20819938 PMID:23636399 RGD:10002730, RGD:10002762 NCBI chr 8:44,733,623...44,735,999
Ensembl chr 8:44,733,029...44,737,271
JBrowse link
G Rps26 ribosomal protein S26 ISO RGD PMID:20819938 PMID:23636399 RGD:10002730, RGD:10002762 NCBI chr 7:1,057,332...1,058,882 JBrowse link
G Rps27 ribosomal protein S27 ISO RGD PMID:20819938 PMID:23636399 RGD:10002730, RGD:10002762 NCBI chr 2:175,665,858...175,666,963
Ensembl chr 2:175,665,853...175,666,964
JBrowse link
G Rps27a ribosomal protein S27a ISO RGD PMID:20819938 PMID:23636399 RGD:10002730, RGD:10002762 NCBI chr14:103,285,734...103,288,011
Ensembl chr14:103,285,734...103,288,011
Ensembl chr 5:103,285,734...103,288,011
JBrowse link
G Rps27l ribosomal protein S27-like ISO RGD PMID:20819938 RGD:10002730 NCBI chr 8:67,562,483...67,567,418
Ensembl chr 8:67,562,483...67,567,418
JBrowse link
G Rps28 ribosomal protein S28 ISO RGD PMID:20819938 PMID:23636399 RGD:10002730, RGD:10002762 NCBI chr 7:14,607,801...14,609,170
Ensembl chr 7:14,607,801...14,609,170
Ensembl chr16:14,607,801...14,609,170
JBrowse link
G Rps29 ribosomal protein S29 ISO RGD PMID:20819938 PMID:23636399 RGD:10002730, RGD:10002762 NCBI chr 6:87,635,229...87,636,627
Ensembl chr 6:87,635,230...87,636,636
JBrowse link
G Rps3 ribosomal protein S3 ISO RGD PMID:20819938 PMID:23636399 RGD:10002730, RGD:10002762 NCBI chr 1:153,778,363...153,783,663
Ensembl chr 1:153,777,472...153,783,680
JBrowse link
G Rps3a ribosomal protein S3a ISO RGD PMID:20819938 PMID:23636399 RGD:10002730, RGD:10002762 NCBI chr 2:171,524,685...171,529,054
Ensembl chr 2:171,524,500...171,529,055
JBrowse link
G Rps4x ribosomal protein S4, X-linked ISO RGD PMID:20819938 PMID:23636399 RGD:10002730, RGD:10002762 NCBI chr  X:67,298,522...67,302,965
Ensembl chr  X:67,298,525...67,303,019
Ensembl chr 4:67,298,525...67,303,019
JBrowse link
G Rps4y2 ribosomal protein S4, Y-linked 2 ISO RGD PMID:20819938 RGD:10002730 NCBI chr 4:181,269,507...181,270,440
Ensembl chr 4:181,269,081...181,270,349
JBrowse link
G Rps5 ribosomal protein S5 ISO RGD PMID:20819938 PMID:23636399 RGD:10002730, RGD:10002762 NCBI chr 1:73,538,776...73,543,073
Ensembl chr 1:73,538,776...73,543,073
JBrowse link
G Rps6 ribosomal protein S6 ISO RGD PMID:20819938 PMID:23636399 RGD:10002730 RGD:10002762 NCBI chr 5:101,371,716...101,374,576
Ensembl chr 5:101,371,136...101,374,602
Ensembl chr 5:101,371,136...101,374,602
JBrowse link
G Rps7 ribosomal protein S7 ISO RGD PMID:20819938 PMID:23636399 RGD:10002730, RGD:10002762 NCBI chr 6:45,266,200...45,271,064
Ensembl chr 6:45,223,980...45,271,145
JBrowse link
G Rps8 ribosomal protein S8 ISO RGD PMID:20819938 PMID:23636399 RGD:10002730, RGD:10002762 NCBI chr 5:130,630,362...130,632,932
Ensembl chr 5:130,629,716...130,633,268
JBrowse link
G Rps9 ribosomal protein S9 ISO RGD PMID:20819938 PMID:23636399 RGD:10002730 RGD:10002762 NCBI chr 1:65,511,723...65,515,076
Ensembl chr 1:65,511,723...65,515,123
JBrowse link
G Rpsa ribosomal protein SA ISO RGD PMID:20819938 PMID:23636399 RGD:10002730, RGD:10002762 NCBI chr 8:119,851,225...119,855,103
Ensembl chr 8:119,851,225...119,855,247
JBrowse link
G Rrp12 ribosomal RNA processing 12 ISO RGD PMID:24424021 RGD:10002751 NCBI chr 1:240,672,378...240,705,992
Ensembl chr 1:240,672,382...240,706,018
JBrowse link
G Rrp7a ribosomal RNA processing 7 homolog A IEA KEGG rno:03008 NCBI chr 7:114,262,929...114,272,817
Ensembl chr 7:114,256,472...114,272,817
JBrowse link
G Sbds Sbds, ribosome maturation factor IEA KEGG rno:03008 NCBI chr12:26,420,410...26,429,650
Ensembl chr12:26,420,414...26,429,649
JBrowse link
G Snu13 small nuclear ribonucleoprotein 13 IEA
ISO
KEGG
RGD
PMID:22065625 rno:03008, RGD:9999451 NCBI chr 7:113,565,293...113,570,887
Ensembl chr 7:113,565,295...113,570,872
Ensembl chr 1:113,565,295...113,570,872
JBrowse link
G Snu13l1 small nuclear ribonucleoprotein 13 like 1 IEA KEGG rno:03008 NCBI chr  X:150,624,087...150,624,525
Ensembl chr  X:150,624,087...150,624,473
JBrowse link
G Taf9 TATA-box binding protein associated factor 9 IEA KEGG rno:03008 NCBI chr 2:31,794,316...31,798,324
Ensembl chr 2:31,794,142...31,798,769
JBrowse link
G Tbl3 transducin (beta)-like 3 IEA KEGG rno:03008 NCBI chr10:13,726,127...13,731,340
Ensembl chr10:13,726,129...13,731,372
JBrowse link
G Tcof1 treacle ribosome biogenesis factor 1 IEA KEGG rno:03008 NCBI chr18:54,267,015...54,300,324
Ensembl chr18:54,267,026...54,300,324
JBrowse link
G Uba52 ubiquitin A-52 residue ribosomal protein fusion product 1 ISO RGD PMID:23636399 RGD:10002762 NCBI chr16:18,918,614...18,920,807
Ensembl chr16:18,900,616...18,920,807
JBrowse link
G Utp14a UTP14A small subunit processome component IEA KEGG rno:03008 NCBI chr  X:127,439,282...127,464,634
Ensembl chr  X:127,439,268...127,464,633
JBrowse link
G Utp15 UTP15, small subunit processome component IEA KEGG rno:03008 NCBI chr 2:29,594,405...29,612,819
Ensembl chr 2:29,594,941...29,612,773
JBrowse link
G Utp18 UTP18 small subunit processome component IEA KEGG rno:03008 NCBI chr10:78,811,879...78,839,338
Ensembl chr10:78,811,880...78,839,627
JBrowse link
G Utp23 UTP23, small subunit processome component ISO RGD PMID:24550520 RGD:9999445 NCBI chr 7:83,185,187...83,196,652
Ensembl chr 7:83,189,656...83,196,655
JBrowse link
G Utp4 UTP4 small subunit processome component IEA KEGG rno:03008 NCBI chr19:34,790,962...34,820,558
Ensembl chr19:34,792,457...34,820,550
JBrowse link
G Utp6 UTP6 small subunit processome component IEA KEGG rno:03008 NCBI chr10:64,897,321...64,927,997
Ensembl chr10:64,897,328...64,927,997
JBrowse link
G Wdr3 WD repeat domain 3 IEA
ISO
KEGG
RGD
PMID:24550520 rno:03008, RGD:9999445 NCBI chr 2:187,505,816...187,528,432
Ensembl chr 2:187,505,816...187,528,432
JBrowse link
G Wdr43 WD repeat domain 43 IEA KEGG rno:03008 NCBI chr 6:23,845,499...23,884,846
Ensembl chr 6:23,845,499...23,884,846
JBrowse link
G Wdr75 WD repeat domain 75 IEA KEGG rno:03008 NCBI chr 9:47,903,214...47,933,399
Ensembl chr 9:47,903,200...47,933,399
JBrowse link
G Xpo1 exportin 1 IEA
ISO
KEGG
RGD
PMID:17509569 PMID:25802992 rno:03008, RGD:10002749, RGD:10002750 NCBI chr14:97,233,282...97,275,536
Ensembl chr14:97,233,270...97,275,498
JBrowse link
G Xpo5 exportin 5 ISO RGD PMID:25802992 RGD:10002750 NCBI chr 9:14,740,182...14,778,171
Ensembl chr 9:14,740,182...14,778,171
JBrowse link
G Xrn1 5'-3' exoribonuclease 1 IEA KEGG rno:03008 NCBI chr 8:96,527,871...96,637,385
Ensembl chr 8:96,528,195...96,632,739
JBrowse link
G Xrn2 5'-3' exoribonuclease 2 IEA
ISO
KEGG
RGD
PMID:24550520 rno:03008, RGD:9999445 NCBI chr 3:134,436,916...134,509,308
Ensembl chr 3:134,437,109...134,509,306
JBrowse link

Pathway Gene Annotations

Disease Annotations Associated with Genes in the ribosome biogenesis pathway
Disease TermsGene Symbols
16Q24.3 Microdeletion SyndromeRpl13
3-hydroxy-3-methylglutaryl-CoA lyase deficiencyRpl11
3-methylglutaconic aciduria type 7bRps3
achondrogenesis type IADdx24
acute lymphoblastic leukemiaNup214
acute myeloid leukemiaDhx15 , Nup214
adenoid cystic carcinomaXrn2
adenylosuccinase lyase deficiencyCsnk1e , Nol12 , Rpl3 , Snu13
adrenoleukodystrophyDkc1 , Rpl10
adult T-cell leukemia/lymphomaCsnk2a1 , Csnk2b , Prkcb
advanced sleep phase syndrome 1Csnk1d
advanced sleep phase syndrome 2Csnk1d
agammaglobulinemia 3Rps19
agenesis of the corpus callosum with peripheral neuropathyNop10
alcohol use disorderRpl18a
alopecia, neurologic defects, and endocrinopathy syndromeRbm28
Alzheimer's diseaseCsnk1d , Csnk1e , Prkcb , Xrn1
amenorrheaEri1 , Xpo1
amyotrophic lateral sclerosisMtrex
anauxetic dysplasia 1Pop1
anauxetic dysplasia 2Pop1
anemiaDkc1 , Rpl11 , Rps26
Animal Disease ModelsFbl , Gar1 , Nop56 , Nop58 , Rcl1 , Rpl10a , Rpl13a , Rpl27a , Rpl36a , Rpsa
Animal Mammary NeoplasmsRan , Rpl3 , Rpl6 , Rps14
Anodontia of Permanent DentitionSbds
AnorchiaDhx37
aplastic anemiaDkc1 , Rpl5 , Sbds
argininosuccinic aciduriaSbds
arrhythmogenic right ventricular dysplasia 5Rpsa
ataxia telangiectasiaDdx10
atrial fibrillationRps2 , Xpo1
attention deficit hyperactivity disorderCsnk1d
autism spectrum disorderCsnk2a1 , Csnk2b
autistic disorderDkc1 , Gnl3l , Nxf3 , Nxf7 , Nxt2 , Prkcb , Pwp2 , Rpl10 , Rpl17 , Rpl36a , Rpl39 , Rpp25 , Rps28 , Rps4x , Rps4y2 , Utp14a
autoimmune diseaseFbl
autoimmune lymphoproliferative syndrome type 2BNop58
Autoimmune Lymphoproliferative Syndrome, Type VNop58
autosomal dominant dyskeratosis congenita 6Nob1 , Utp4
autosomal dominant intellectual developmental disorderCsnk2b
autosomal dominant intellectual developmental disorder 5Rps18
autosomal recessive chronic granulomatous disease 4Rpl13
Autosomal Recessive Dyskeratosis CongenitaNhp2 , Nop10
autosomal recessive dyskeratosis congenita 1Nhp2 , Nop10
autosomal recessive dyskeratosis congenita 2Nhp2
autosomal recessive limb-girdle muscular dystrophy type 2KNup214
B-Cell Chronic Lymphocytic LeukemiaDkc1 , Xpo1
Bardet-Biedl syndromeCsnk2a2 , Fau
Barth syndromeDkc1 , Rpl10
basal cell carcinomaDhx15
Beckwith-Wiedemann syndromeRplp2
bladder exstrophy-epispadias-cloacal exstrophy complexEif6 , Rpl4
Bloom syndromeEfl1 , Imp3 , Nop10 , Rpl4 , Rplp1 , Rpp25 , Rps17 , Rps27l
bone marrow diseaseRps26
Bowen-Conradi syndromeEmg1
brachycephaly, trichomegaly, and developmental delayRps23
brain diseaseNup214
Brain InjuriesBysl , Lsg1 , Rps27a , Uba52
Brain-Lung-Thyroid SyndromeRps29
breast cancerCsnk2a1 , Xpo5
Breast NeoplasmsEif6 , Fbl , Rpl23a , Rpl31 , Rplp2 , Rps4x , Rps6 , Rps7 , Rps8 , Xpo1
Brown-Vialetto-Van Laere syndrome 1Csnk2a1
Brown-Vialetto-Van Laere syndrome 2Bop1
carcinomaRan , Rpl3 , Rpl6 , Rps14
Cardiac ArrhythmiasCsnk1e
CardiomegalyPrkcb
Carpenter Syndrome 2Exosc5 , Fbl , Rps16 , Rps19
cataract 9 multiple typesPwp2
Cataracts, Hearing Impairment, Nephrotic Syndrome, and Enterocolitis 1Dkc1
Cataracts, Hearing Impairment, Nephrotic Syndrome, and Enterocolitis 2Nop10
CD3epsilon deficiencyRps25
cerebellar ataxiaNop56 , Rpl27a
CEREBELLAR ATAXIA, BRAIN ABNORMALITIES, AND CARDIAC CONDUCTION DEFECTSExosc5
cerebellar hypoplasiaDkc1
cerebral creatine deficiency syndromeRps15
cerebral creatine deficiency syndrome 1Dkc1 , Rpl10
cerebral palsyUtp6
Chanarin-Dorfman syndromeRplp2
Charcot-Marie-Tooth disease dominant intermediate CGnl2 , Rps8
Charcot-Marie-Tooth disease type 2Exosc10
Charcot-Marie-Tooth disease type XNxt2 , Utp14a
Chediak-Higashi syndromeHeatr1
cholangiocarcinomaPes1
cholestasisUtp4
Chromosomal InstabilityRps3
Chromosome 11, Partial Trisomy 11qDdx10 , Rexo2 , Rps25
chromosome 13q14 deletion syndromeDis3
chromosome 15q24 deletion syndromeImp3
chromosome 1p36 deletion syndromeExosc10 , Rpl22
chromosome 5q deletion syndromeRps14
chromosome 9p deletion syndromeRcl1
chronic lymphocytic leukemiaXpo1
Cohen syndromePop1
coloboma of optic nerveDhx37
colon carcinomaUba52
colorectal adenocarcinomaUtp23
colorectal cancerEfl1 , Imp3 , Nop10 , Rpl4 , Rplp1 , Rpp25 , Rps17 , Rps27l , Xpo1 , Xpo5
colorectal carcinomaXpo1
Colorectal NeoplasmsPrkcb , Xpo1
common variable immunodeficiency 1Nop58
common variable immunodeficiency 4Rrp7a , Snu13
congenital disorder of glycosylation InGnl3
congenital hypoplastic anemiaExosc5 , Fbl , Rpl19 , Rpl26 , Rpl35a , Rpl5 , Rps10 , Rps16 , Rps19 , Rps24 , Rps7
congestive heart failurePrkcb
Cornelia de Lange syndrome 2Gnl3l
Cornelia de Lange syndrome 4Utp23
Costello syndromeRplp2
COVID-19Pals2
Craniofacial AbnormalitiesTcof1
craniosynostosisExosc5 , Fbl , Rps16 , Rps19
Crouzon syndromeTcof1
cyclic hematopoiesisRexo1 , Rps15
delta beta-thalassemiaRplp2
desmoplastic/nodular medulloblastomaPdcd11
developmental and epileptic encephalopathyCsnk2a2 , Nup214 , Rpl12 , Rplp2 , Rps21-ps1 , Rps8
developmental and epileptic encephalopathy 1Csnk1e , Rps2 , Tbl3
developmental and epileptic encephalopathy 12Rpl13a , Rps11
developmental and epileptic encephalopathy 14Rpl7a
developmental and epileptic encephalopathy 21Emg1
developmental and epileptic encephalopathy 25Nup88
developmental and epileptic encephalopathy 30Pwp2
developmental and epileptic encephalopathy 31ARpl12
developmental and epileptic encephalopathy 33Rps21-ps1
developmental and epileptic encephalopathy 9Nxf7 , Rpl36a
Developmental Delay with Variable Intellectual Impairment and Behavioral AbnormalitiesRrp7a
Developmental DisabilitiesEri1 , Nup214
Developmental DiseaseCsnk2a1 , Nup214
Diabetic NephropathiesPrkcb , Uba52
Diamond-Blackfan anemiaExosc5 , Fbl , Rpl11 , Rpl19 , Rpl26 , Rpl35a , Rpl5 , Rps10 , Rps16 , Rps17 , Rps19 , Rps20 , Rps24 , Rps26 , Rps7 , Rpsa
Diamond-Blackfan anemia 1Rpl5 , Rps19
Diamond-Blackfan anemia 10Rps26
Diamond-Blackfan anemia 11Rpl26
Diamond-Blackfan anemia 12Rpl15
Diamond-Blackfan anemia 13Rps29
Diamond-Blackfan anemia 15 with mandibulofacial dysostosisRps26 , Rps28
Diamond-Blackfan anemia 16Rpl27
Diamond-Blackfan anemia 17Rps27
Diamond-Blackfan anemia 18Rpl18
Diamond-Blackfan anemia 19Rpl35
Diamond-Blackfan anemia 20Rps15a
Diamond-Blackfan anemia 3Rps24
Diamond-Blackfan anemia 4Rps17
Diamond-Blackfan anemia 5Rpl35a
Diamond-Blackfan anemia 6Rpl5
Diamond-Blackfan anemia 7Rpl11
Diamond-Blackfan anemia 8Rps7
Diamond-Blackfan anemia 9Rps10
DICER1 syndromeDdx24
dilated cardiomyopathyPrkcb
disease of cellular proliferationDkc1
Disease ProgressionBop1 , Exosc5 , Nop56 , Rpl13 , Rpl15 , Rpl18 , Rps15 , Rps19 , Rps21-ps1 , Rps26 , Rps6
Down syndromeRplp0
DwarfismRps25 , Sbds
dyschromatosis symmetrica hereditariaRps27
dyskeratosis congenitaDkc1 , Gar1 , Nhp2 , Nop10 , Rpl10 , Rpl26
dystoniaMphosph10
early infantile epileptic encephalopathyCsnk2a2 , Nup214 , Rpl12 , Rplp2 , Rps21-ps1 , Rps8
ectodermal dysplasiaBms1
Ehlers-Danlos syndrome classic type 1Rpl7a , Wdr75
Ehlers-Danlos syndrome dermatosparaxis typeNhp2
Ehlers-Danlos Syndrome Type 4Wdr75
Emery-Dreifuss muscular dystrophyCsnk1e , Dkc1 , Nol12 , Rpl10
ENCEPHALOPATHY, ACUTE, INFECTION-INDUCED, 9Nup214
end stage renal diseaseGtpbp4
enophthalmosCsnk2b , Sbds
epidermolysis bullosa simplex with muscular dystrophyBop1
epilepsyAfg2a , Csnk2b , Dhx15 , Dhx37 , Imp3 , Rps2 , Tbl3 , Xpo1
esophagus squamous cell carcinomaXpo1
Experimental Autoimmune MyocarditisRps6
Experimental Diabetes MellitusPrkcb , Uba52
Experimental Liver CirrhosisPrkcb
Experimental Mammary NeoplasmsCsnk2a1 , Ran , Rpl3 , Rpl6 , Rps14
extrahepatic bile duct carcinomaXpo1
Fabry diseaseRpl36a
FaciesNup214
familial adenomatous polyposis 1Riok2 , Rps14 , Tcof1
Familial Atrial Fibrillation 14Rps25
Familial Atrial Fibrillation 6Exosc10
familial hemophagocytic lymphohistiocytosis 4Ltv1
familial hyperinsulinemic hypoglycemia 1Nxt1 , Xrn2
Fanconi anemiaRpl13
favismDkc1 , Rpl10
fetal akinesia deformation sequence syndrome 4Nup88
Fetal DiseasesPrkcb
focal segmental glomerulosclerosisNxf7
GAND syndromeRps27
gastric adenocarcinomaXpo1
gastrointestinal stromal tumorHeatr1 , Nvl , Rpl24 , Rps27
Generalized EpilepsyCsnk1d
genetic diseaseAfg2a , Csnk2a1 , Csnk2b , Dhx37 , Efl1 , Emg1 , Exosc5 , Mdn1 , Nop56 , Nxf7 , Pop1 , Riok3 , Rpl10 , Rpl11 , Rpl13 , Rpl5 , Rps10 , Rps29 , Sbds , Tcof1
Genitopatellar SyndromeRps24
glioblastomaHeatr1 , Rpl35a , Rpl5
glutathione synthetase deficiencyEif6
glycogen storage disease IbRps25
glycogen storage disease VFau
Growth DisordersNup214
Hearing LossTcof1
Hearing Loss, Noise-InducedNob1
hematopoietic system diseaseGar1
HemimegalencephalyRps6
hepatoblastomaRps19
hepatocellular carcinomaRps6 , Xpo1 , Xpo5
hereditary multiple exostosesUtp23
Hereditary Neoplastic SyndromesNop10 , Riok2 , Rps14 , Rps20 , Tcof1
herpes simplexRpl30
high grade gliomaEfl1 , Fau
High MyopiaRpl4
holoprosencephalyBop1
homocystinuriaPwp2
Hoxha-Aliu syndromeEri1
Hoyeraal Hreidarsson SyndromeDkc1
human immunodeficiency virus infectious diseaseEif6 , Emg1 , Nup88 , Ran , Taf9
Huntington's diseaseXpo5
Huntington's disease-like 1Nop56
HyperalgesiaPrkcb
hyperargininemiaDhx37
hyperglycemiaPrkcb
Hyperglycinemia, Lactic Acidosis, and SeizuresRpl9
Hyperphosphatemic Familial Tumoral Calcinosis 1Emg1
HyperpigmentationRpl27a
hypertensionPrkcb
HypertriglyceridemiaRps12
hypertrophic cardiomyopathyRps27l
hypertrophic cardiomyopathy 11Nop10
Hypoglossal Nerve InjuriesCsnk2b
hypomyelinating leukodystrophy 11Xpo5
hypomyelinating leukodystrophy 7Rps24
hypoparathyroidism-deafness-renal disease syndromeRpp38
hypotrichosisRpl21
hypotrichosis 12Rpl21
HypoxiaRps14 , Rps2
idiopathic generalized epilepsyRps2 , Tbl3
immune system diseasePrkcb
immunodeficiency 14Exosc10
immunodeficiency 17Rps25
immunodeficiency 18Rps25
immunodeficiency 19Rps25
immunodeficiency 31BWdr75
immunodeficiency 33Dkc1 , Rpl10
immunodeficiency 39Rplp2
immunodeficiency 42Rps27
infantile Refsum diseaseBysl , Xpo5
inflammatory bowel disease 28Rps25
inflammatory poikiloderma with hair abnormalities and acral keratosesLtv1
Insulin ResistancePrkcb
insulinomaRps15
intellectual disabilityCsnk2a1 , Csnk2b , Ddx10 , Dhx37 , Fau , Fcf1 , Nxf1 , Rexo2 , Riok3 , Rpl17 , Rps13 , Rps3 , Rrp7a , Sbds
invasive ductal carcinomaCsnk1e
irritable bowel syndromeRpsa
isolated growth hormone deficiency type IIINxf7 , Rpl36a
isolated microphthalmia 5Rps25
KBG syndromeRpl13
KeloidRan
Klippel-Feil syndrome 3Emg1
Lead PoisoningXpo5
Left Ventricular HypertrophyPrkcb
Leigh diseaseRpl7a
leiomyomaCsnk2b
leiomyosarcomaXrn2
leukocyte adhesion deficiency 3Fau , Nxf1
Li-Fraumeni syndromeRpl26
Liver FailureRps10 , Rps6 , Rps9
long QT syndromeMdn1
long QT syndrome 10Rps25
lung adenocarcinomaFbl , Gar1 , Nop56 , Nop58 , Rcl1 , Rpl10a , Rpl13a , Rpl27a , Rpl36a , Rpsa , Xpo1
lung cancerXrn2
lung carcinomaXpo1
lung non-small cell carcinomaPrkcb , Xpo1 , Xpo5
lung small cell carcinomaXpo5
lymphomaRpl11
lymphopeniaDkc1
lymphoproliferative syndrome 2Emg1
Lynch syndromeRps20
male infertilityCsnk2a2
Malocclusion, Angle Class IIICsnk2b
Mandibulofacial DysostosisTcof1
maple syrup urine diseaseExosc5 , Fbl , Rps16 , Rps19
Marfanoid Mental Retardation Syndrome, AutosomalMtrex
maturity-onset diabetes of the young type 1Fbl , Rps16
megacolonCsnk2b
Megalencephaly-Polymicrogyria-Polydactyly-Hydrocephalus Syndrome 1Rpl18a , Uba52
melanomaRpp38 , Rps3
metachondromatosisRpl6
Methylmalonyl-CoA Epimerase DeficiencyMphosph10
MHC class I deficiencyRps18
MHC class II deficiencyRps27
microcephalyNup214 , Rbm28 , Sbds , Tcof1
Microsatellite InstabilityXpo5
middle cerebral artery infarctionRpl28
morphine dependenceRack1
Mouth NeoplasmsRack1
mucolipidosis type IVRps28
multiple myelomaDis3 , Xpo5
myocardial infarctionCsnk2a1 , Csnk2b
Myocardial IschemiaRpl17
Myocardial Reperfusion InjuryPrkcb
myoclonic dystonia 26Csnk1e , Nol12
myoepitheliomaRpl36
nemaline myopathy 6Rps27l
Neoplasm InvasivenessRpsa
nephroblastomaXpo5
nephrotic syndrome type 2Xpo5
Neuroblastoma 3Wdr43
neurodegeneration with brain iron accumulation 2ACsnk1e , Nol12
NEURODEVELOPMENTAL DISORDER WITH BRAIN ANOMALIES AND WITH OR WITHOUT VERTEBRAL OR CARDIAC ANOMALIESDhx37
neurodevelopmental disorder with hearing loss, seizures, and brain abnormalitiesAfg2a
Neurodevelopmental DisordersAfg2a , Csnk2a1 , Csnk2b , Ddx10 , Dhx37 , Eri1 , Mtrex , Nop58 , Pwp2 , Rexo1 , Riok2 , Rpl22 , Rpl37 , Rpl37a , Rps15 , Rps23 , Taf9 , Utp15 , Wdr75
neuronal ceroid lipofuscinosisRpl4 , Rplp2 , Rps21-ps1
neutropeniaRps14
Niemann-Pick disease type C1Riok3
nonsyndromic aplasia cutis congenitaBms1
Noonan syndrome 1Rpl6
Noonan syndrome with multiple lentigines 1Rpl6
North American Indian Childhood CirrhosisUtp4
obesityPrkcb
Okur-Chung Neurodevelopmental SyndromeCsnk2a1
optic atrophyRpl24
osteoarthritisRan
otitis mediaRpl38
ovarian cystRpl5
Ovarian NeoplasmsPop4
Oxygen-Induced RetinopathyCsnk2a1 , Csnk2a2 , Csnk2b
pancreatic cancerXpo1 , Xpo5
pancreatic ductal carcinomaHeatr1
pancytopeniaRpl27a
pantothenate kinase-associated neurodegenerationNop56
PAPA syndromeImp3 , Rpp25
papillary thyroid carcinomaWdr3
paraplegiaDkc1 , Rpl10
parathyroid carcinomaHeatr1 , Nvl , Rps27
Parkinson's diseaseRpl14 , Rpl23a , Rpl6 , Rps8
periventricular nodular heterotopiaDkc1 , Rpl10
Perlman syndromeDis3
peroxisome biogenesis disorder 11AXpo1
peroxisome biogenesis disorder 2BEmg1
pleomorphic xanthoastrocytomaDdx56 , Pals2 , Pop7 , Rbm28 , Sbds
pleuropulmonary blastomaDdx24
POIRIER-BIENVENU NEURODEVELOPMENTAL SYNDROMECsnk2b
polycystic ovary syndromeRexo1 , Rpl37a
Polyglucosan Body Myopathy 1 with or without ImmunodeficiencyCsnk2a1
Primary Autosomal Recessive Microcephaly 28Rrp7a
primary biliary cholangitisUtp4
primary ciliary dyskinesiaPwp2 , Rps29
primary ciliary dyskinesia 33Rpl13
primary coenzyme Q10 deficiency 7Nup214 , Rpl7a
primary immunodeficiency diseaseDkc1
primary ovarian insufficiencyXpo5
primary pulmonary hypertensionNop58
primary pulmonary hypertension 1Nop58
progressive myoclonus epilepsyPwp2
progressive myoclonus epilepsy 9Rexo1
prostate adenocarcinomaXpo1
prostate cancerNmd3
Prostatic NeoplasmsRpl10 , Rpl11 , Rpl12 , Rps19 , Xpo1
proteasome-associated autoinflammatory syndrome 1Csnk2b , Rpl10a , Rps10 , Rps18
psychotic disorderRcl1
Pulmonary Arterial HypertensionNop58
pulmonary fibrosisDkc1
Pulmonary Fibrosis and/or Bone Marrow Failure Syndrome, Telomere-Related, 9Nop10
Rafiq syndromeRpl7a
RASopathyRpl6 , Rps25
renal cell carcinomaRpl14
ROLANDIC EPILEPSY, INTELLECTUAL DISABILITY, AND SPEECH DYSPRAXIA, X-LINKEDRpl36a
Rubinstein-Taybi syndromeRpl3
schizophreniaAfg2a , Imp3 , Rpp25 , Rps19 , Rps25 , Xpo1
sciatic neuropathyRan , Rpsa
Segawa Syndrome, Autosomal RecessiveRplp2
sensorineural hearing lossPrkcb
SepsisRpl4 , Rpl9
severe combined immunodeficiency, autosomal recessive, T cell-negative, B cell-negative, NK cell-positiveRpl18a
Severe Combined Immunodeficiency, Autosomal Recessive, T Cell-Negative, B Cell-Positive, NK Cell-NegativeRpl18a
severe congenital encephalopathy due to MECP2 mutationRpl10
severe congenital neutropenia 2Rpl5
severe congenital neutropenia 3Rps27
severe congenital neutropenia 5Rps27
short chain acyl-CoA dehydrogenase deficiencyPop5 , Rplp0
short-rib thoracic dysplasia 9 with or without polydactylyRps2 , Tbl3
Shwachman-Diamond syndromeSbds
Shwachman-Diamond Syndrome 2Efl1
silicosisPrkcb
Skin NeoplasmsCsnk2a1 , Csnk2a2 , Csnk2b
Sotos syndromeNhp2
spermatogenic failure 5Dhx37
spermatogenic failure 57Dhx37
Spinal Cord InjuriesRpsa
spinocerebellar ataxia type 36Nop56
Spinocerebellar AtaxiasNop56
Splenic HypoplasiaRpsa
SplenomegalyDkc1 , Rpl10 , Sbds
spondyloepimetaphyseal dysplasiaRpl13
Spondyloepimetaphyseal Dysplasia, Guo-Campeau TypeEri1
Spondyloepimetaphyseal Dysplasia, Isidor-Toutain TypeRpl13
squamous cell carcinomaCsnk2a1 , Csnk2a2 , Csnk2b , Rack1
Staphylococcal InfectionsXrn1
status epilepticusPrkcb , Xrn2
stomach cancerXpo1
stomach carcinomaXpo1
Stomach NeoplasmsBop1 , Exosc5 , Nop56 , Prkcb , Rpl13 , Rpl15 , Rpl18 , Rps15 , Rps19 , Rps21-ps1 , Rps26 , Rps6
syndactylyCsnk2b
syndromic X-linked intellectual disability 14Rpl39
syndromic X-linked intellectual disability 35Rpl10
syndromic X-linked intellectual disability Cabezas typeRpl39
syndromic X-linked intellectual disability Lubs typeGnl3l , Nxf3 , Nxf7 , Nxt2 , Rpl10 , Rpl36a , Rpl39 , Rps4x , Utp14a
syndromic X-linked intellectual disability Raymond typeUtp14a
systemic lupus erythematosusRpl12 , Rpl14
T-cell acute lymphoblastic leukemiaRpl10 , Rpl11 , Rpl5
Temporomandibular Joint OsteoarthritisRps6
Temtamy syndromeEmg1
transient cerebral ischemiaRack1 , Rps6
transitional cell carcinomaXpo5
Treacher Collins syndromeTcof1
Treacher Collins syndrome 1Tcof1
trichorhinophalangeal syndrome type IUtp23
trichorhinophalangeal syndrome type IIIUtp23
tuberous sclerosis 1Rpl7a
tuberous sclerosis 2Rps2 , Tbl3
type 1 diabetes mellitusRan
type 2 diabetes mellitusFbl , Prkcb , Rps16
uterine cancerXpo1
vascular dementiaRps6
Weight GainRpl28 , Rps28 , Rps8
X-linked dyskeratosis congenitaDkc1
Y-linked spermatogenic failure 2Rps4y2
Zellweger syndromeBysl , Xpo5
Pathway Annotations Associated with Genes in the ribosome biogenesis pathway
Pathway TermsGene Symbols
3'-end pre-mRNA processing pathwayXrn2
aldosterone signaling pathwayPrkcb
B cell receptor signaling pathwayPrkcb
Bone morphogenetic proteins signaling pathwayNup214
calcium/calcium-mediated signaling pathwayPrkcb
chemokine mediated signaling pathwayPrkcb
CRM1 export pathwayNxf3 , Ran , Xpo1
de novo purine biosynthetic pathwayTaf9
E-cadherin signaling pathwayCsnk2a1 , Csnk2a2 , Csnk2b
Entamoebiasis pathwayPrkcb
epidermal growth factor/neuregulin signaling pathwayPrkcb
Fc gamma receptor mediated signaling pathwayPrkcb
glioma pathwayPrkcb
glutamate signaling pathwayPrkcb
gonadotropin-releasing hormone signaling pathwayPrkcb
Hedgehog signaling pathwayCsnk1d , Csnk1e , Xpo1
hypoxia inducible factor pathwayRack1
influenza A pathwayNxf1 , Nxf3 , Nxf7 , Nxt1 , Nxt2 , Prkcb , Xpo1
insulin signaling pathwayPrkcb , Rps6
insulin-like growth factor signaling pathwayRack1
interleukin-2 signaling pathwayPrkcb
Leishmaniasis pathwayPrkcb
long term depressionPrkcb
long term potentiationPrkcb
measles pathwayCsnk2a1 , Csnk2a2 , Csnk2b , Rack1
microRNA pathwayRan , Xpo5
mitochondrial autophagy pathwayCsnk2a1 , Csnk2a2 , Csnk2b
mitogen activated protein kinase signaling pathwayPrkcb
mRNA decay pathwayNxf1 , Nxf3 , Nxf7 , Nxt1 , Nxt2
mRNA nuclear export pathwayNup214
mTOR signaling pathwayRps6
non-small cell lung carcinoma pathwayPrkcb
nuclear factor kappa B signaling pathwayCsnk2a1 , Csnk2a2 , Csnk2b , Ran , Xpo1
NXF1-NXT1 export pathwayNup214 , Nxf1 , Nxt1
p53 signaling pathwayCsnk1d , Csnk1e , Rpl11 , Rpl23 , Rpl5
phosphatidylinositol 3-kinase signaling pathwayPrkcb
platelet-derived growth factor signaling pathwayCsnk2a1
protein kinase C (PKC) signaling pathwayPrkcb , Rack1
ribosome biogenesis pathway1700009N14Rikl , Afg2a , Bms1 , Bop1 , Bysl , C1d , Csnk1d , Csnk1e , Csnk2a1 , Csnk2a2 , Csnk2b , Ddx10 , Ddx18 , Ddx24 , Ddx56 , Dhx15 , Dhx37 , Dis3 , Dkc1 , Efl1 , Eif6 , Emg1 , Eri1 , Exosc10 , Exosc5 , Fau , Fbl , Fbll1 , Fcf1 , Gar1 , Gnl2 , Gnl3 , Gnl3l , Gtpbp4 , Heatr1 , Imp3 , Imp4 , Lsg1 , Ltv1 , Mdn1 , Mphosph10 , Mtrex , Nhp2 , Nmd3 , Nob1 , Nol12 , Nop10 , Nop56 , Nop58 , Nup214 , Nup88 , Nvl , Nxf1 , Nxf3 , Nxf7 , Nxt1 , Nxt2 , Pals2 , Pdcd11 , Pes1 , Pno1 , Pop1 , Pop4 , Pop5 , Pop7 , Prkcb , Pwp2 , Rack1 , Ran , Rasl2-9 , Rbm28 , Rcl1 , Rexo1 , Rexo1l1-ps1 , Rexo2 , Rexo5 , Riok1 , Riok2 , Riok3 , Rpl10 , Rpl10a , Rpl11 , Rpl12 , Rpl13 , Rpl13a , Rpl14 , Rpl15 , Rpl17 , Rpl18 , Rpl18a , Rpl19 , Rpl21 , Rpl22 , Rpl23 , Rpl23a , Rpl24 , Rpl26 , Rpl27 , Rpl27a , Rpl28 , Rpl29 , Rpl3 , Rpl30 , Rpl31 , Rpl32 , Rpl34 , Rpl35 , Rpl35a , Rpl36 , Rpl36a , Rpl37 , Rpl37a , Rpl37l1 , Rpl38 , Rpl39 , Rpl4 , Rpl5 , Rpl6 , Rpl7 , Rpl7a , Rpl8 , Rpl9 , Rplp0 , Rplp1 , Rplp2 , Rpp25 , Rpp30 , Rpp38 , Rpp40 , Rps10 , Rps11 , Rps12 , Rps13 , Rps14 , Rps15 , Rps15a , Rps16 , Rps17 , Rps18 , Rps19 , Rps2 , Rps20 , Rps21 , Rps21-ps1 , Rps23 , Rps24 , Rps25 , Rps26 , Rps27 , Rps27a , Rps27l , Rps28 , Rps29 , Rps3 , Rps3a , Rps4x , Rps4y2 , Rps5 , Rps6 , Rps7 , Rps8 , Rps9 , Rpsa , Rrp12 , Rrp7a , Sbds , Snu13 , Snu13l1 , Taf9 , Tbl3 , Tcof1 , Uba52 , Utp14a , Utp15 , Utp18 , Utp23 , Utp4 , Utp6 , Wdr3 , Wdr43 , Wdr75 , Xpo1 , Xpo5 , Xrn1 , Xrn2
RNA degradation pathwayC1d , Dis3 , Exosc5 , Mtrex , Xrn1 , Xrn2
RNA polymerase II transcription initiation pathwayTaf9
RNA polymerase II transcription termination pathwayXrn2
RNA transport pathway1700009N14Rikl , Nmd3 , Nup214 , Nup88 , Nxf1 , Nxf3 , Nxf7 , Nxt1 , Nxt2 , Pop1 , Pop4 , Pop5 , Pop7 , Ran , Rasl2-9 , Rpp25 , Rpp30 , Rpp38 , Rpp40 , Xpo1 , Xpo5
sleeping sickness pathwayPrkcb
spliceosome pathwayDhx15 , Snu13 , Snu13l1
syndecan signaling pathwayRack1
translation pathwayFau , Rpl10 , Rpl10a , Rpl11 , Rpl12 , Rpl13 , Rpl13a , Rpl14 , Rpl15 , Rpl17 , Rpl18 , Rpl18a , Rpl19 , Rpl21 , Rpl22 , Rpl23 , Rpl23a , Rpl24 , Rpl26 , Rpl27 , Rpl27a , Rpl28 , Rpl29 , Rpl3 , Rpl30 , Rpl31 , Rpl32 , Rpl34 , Rpl35 , Rpl35a , Rpl36 , Rpl36a , Rpl37 , Rpl37a , Rpl37l1 , Rpl38 , Rpl39 , Rpl4 , Rpl5 , Rpl6 , Rpl7 , Rpl7a , Rpl8 , Rpl9 , Rplp0 , Rplp1 , Rplp2 , Rps10 , Rps11 , Rps12 , Rps13 , Rps14 , Rps15 , Rps15a , Rps16 , Rps17 , Rps18 , Rps19 , Rps2 , Rps20 , Rps21 , Rps21-ps1 , Rps23 , Rps24 , Rps25 , Rps26 , Rps27 , Rps27a , Rps28 , Rps29 , Rps3 , Rps3a , Rps4x , Rps5 , Rps6 , Rps7 , Rps8 , Rps9 , Rpsa , Uba52
tRNA maturation pathwayPop1 , Pop4 , Pop5 , Pop7 , Rpp25 , Rpp30 , Rpp38 , Rpp40
tumor necrosis factor mediated signaling pathwayRack1
vascular endothelial growth factor signaling pathwayPrkcb
Wnt signaling pathwayCsnk1e , Csnk2a1 , Csnk2a2 , Csnk2b , Prkcb

References Associated with the ribosome biogenesis pathway:

Ontology Path Diagram:

paths to the root
paths to the root

Import into Pathway Studio: