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Gene: Bag3 (BAG cochaperone 3) Rattus norvegicus
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Symbol: Bag3
Name: BAG cochaperone 3
Description: Predicted to have adenyl-nucleotide exchange factor activity and chaperone binding activity. Involved in several processes, including central nervous system development; chaperone-mediated autophagy; and negative regulation of protein targeting to mitochondrion. Localizes to the neuron projection and stress fiber. Used to study glioblastoma multiforme. Biomarker of visual epilepsy. Human ortholog(s) of this gene implicated in dilated cardiomyopathy 1HH and myofibrillar myopathy 6. Orthologous to human BAG3 (BAG cochaperone 3); INTERACTS WITH (+)-schisandrin B; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: BAG family molecular chaperone regulator 3; Bcl2-associated athanogene 3; LOC293524
Orthologs:
Homo sapiens (human) : BAG3 (BAG cochaperone 3)  HGNC  Alliance
Mus musculus (house mouse) : Bag3 (BCL2-associated athanogene 3)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Bag3 (BAG cochaperone 3)
Pan paniscus (bonobo/pygmy chimpanzee) : BAG3 (BAG cochaperone 3)
Canis lupus familiaris (dog) : BAG3 (BAG cochaperone 3)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Bag3 (BAG cochaperone 3)
Sus scrofa (pig) : BAG3 (BAG cochaperone 3)
Chlorocebus sabaeus (green monkey) : BAG3 (BAG cochaperone 3)
Heterocephalus glaber (naked mole-rat) : Bag3 (BAG cochaperone 3)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01199,941,258 - 199,965,191 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1199,941,161 - 199,965,191 (+)Ensembl
Rnor_5.01206,989,244 - 207,013,177 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41187,781,147 - 187,804,835 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11187,931,027 - 187,954,715 (+)NCBI
Celera1180,749,355 - 180,773,125 (+)NCBICelera
Cytogenetic Map1q37NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 6.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
 
More on Bag3
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1307794
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2020-02-11
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.