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Gene: Gnaq (G protein subunit alpha q) Rattus norvegicus
Symbol: Gnaq
Name: G protein subunit alpha q
RGD ID: 620770
Description: Exhibits GTP binding activity; alkylglycerophosphoethanolamine phosphodiesterase activity; and type 2A serotonin receptor binding activity. Involved in several processes, including activation of phospholipase C activity; negative regulation of potassium ion transport; and positive regulation of smooth muscle cell proliferation. Localizes to caveola; cytosol; and heterotrimeric G-protein complex. Human ortholog(s) of this gene implicated in Sturge-Weber syndrome and familial multiple nevi flammei. Orthologous to human GNAQ (G protein subunit alpha q); PARTICIPATES IN G protein mediated signaling pathway via Galphaq family; orexin/hypocretin signaling pathway via orexin/hypocretin receptor 1; orexin/hypocretin signaling pathway via orexin/hypocretin receptor 2; INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran.
Type: protein-coding
Also known as: Galphaq; guanine nucleotide binding protein (G protein), q polypeptide; guanine nucleotide binding protein alpha q subunit; guanine nucleotide binding protein, alpha q polypeptide; guanine nucleotide regulatory protein G alpha q; guanine nucleotide-binding protein alpha-q; guanine nucleotide-binding protein G(q) subunit alpha; heterotrimeric guanine nucleotide-binding protein alpha q subunit
Homo sapiens (human) : GNAQ (G protein subunit alpha q)  HGNC  Alliance
Mus musculus (house mouse) : Gnaq (guanine nucleotide binding protein, alpha q polypeptide)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Gnaq (G protein subunit alpha q)
Pan paniscus (bonobo/pygmy chimpanzee) : GNAQ (G protein subunit alpha q)
Canis lupus familiaris (dog) : GNAQ (G protein subunit alpha q)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Gnaq (G protein subunit alpha q)
Sus scrofa (pig) : GNAQ (G protein subunit alpha q)
Chlorocebus sabaeus (African green monkey) : GNAQ (G protein subunit alpha q)
Heterocephalus glaber (naked mole-rat) : Gnaq (G protein subunit alpha q)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
NCBI Annotation Information: Annotation category: partial on reference assembly
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.01233,382,778 - 233,622,584 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1233,382,708 - 233,622,786 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01240,497,178 - 240,736,860 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41219,520,998 - 219,764,401 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11219,685,020 - 219,928,420 (+)NCBI
Celera1210,763,138 - 211,002,668 (+)NCBICelera
Cytogenetic Map1q43NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
More on Gnaq
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 620770
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2020-08-20
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.