Oat (ornithine aminotransferase) - Rat Genome Database

Name: Oat
Creator: Rat Genome Database
License: Creative Commons CC BY 4.0
Keywords: Rat Gene RGD Genome

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Gene: Oat (ornithine aminotransferase) Rattus norvegicus

Analyze

Symbol:

Oat

Name:

ornithine aminotransferase

RGD ID:

621724

Description:

Predicted to enable identical protein binding activity; ornithine aminotransferase activity; and pyridoxal phosphate binding activity. Predicted to be involved in arginine catabolic process to glutamate and arginine catabolic process to proline via ornithine. Predicted to be located in mitochondrial matrix and nucleoplasm. Predicted to be active in cytoplasm. Human ortholog(s) of this gene implicated in gyrate atrophy. Orthologous to human OAT (ornithine aminotransferase); PARTICIPATES IN AGAT deficiency pathway; arginine and proline metabolic pathway; guanidinoacetate methyltransferase deficiency pathway; INTERACTS WITH (+)-schisandrin B; 1,2,4-trimethylbenzene; 1-naphthyl isothiocyanate.

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Previously known as:

ornithine aminotransferase (gyrate atrophy); ornithine aminotransferase, mitochondrial; ornithine--oxo-acid aminotransferase; rOAT

RGD Orthologs

Alliance Genes

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	OAT (ornithine aminotransferase)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, PhylomeDB, Treefam
Mus musculus (house mouse):	Oat (ornithine aminotransferase)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Oat (ornithine aminotransferase)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	OAT (ornithine aminotransferase)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	OAT (ornithine aminotransferase)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Oat (ornithine aminotransferase)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	OAT (ornithine aminotransferase)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	OAT (ornithine aminotransferase)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Oat (ornithine aminotransferase)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Alliance orthologs ³
Mus musculus (house mouse):	Oat (ornithine aminotransferase)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Homo sapiens (human):	OAT (ornithine aminotransferase)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	oat (ornithine aminotransferase)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Saccharomyces cerevisiae (baker's yeast):	CAR2	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Drosophila melanogaster (fruit fly):	Oat	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Caenorhabditis elegans (roundworm):	oatr-1	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	oat	Alliance	DIOPT (Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER)

Related Pseudogenes:

Slc22a7-ps1

Latest Assembly:

mRatBN7.2 - mRatBN7.2 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mRatBN7.2	1	187,347,862 - 187,367,644 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	1	187,347,865 - 187,367,682 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	1	195,698,027 - 195,717,805 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	1	202,876,939 - 202,896,719 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	1	195,550,072 - 195,569,851 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	1	204,562,289 - 204,582,070 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	1	204,562,289 - 204,582,070 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	1	211,555,927 - 211,575,708 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	1	192,026,623 - 192,046,404 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	1	192,176,503 - 192,196,285 (-)	NCBI
Celera	1	185,092,131 - 185,111,563 (-)	NCBI		Celera
Cytogenetic Map	1	q41	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

Experimental Liver Cirrhosis (ISO)

fundus dystrophy (ISO)

genetic disease (ISO)

gyrate atrophy (ISO,ISS)

Liver Neoplasms (ISO)

optic atrophy (ISO)

perinatal necrotizing enterocolitis (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(+)-schisandrin B (EXP)

1,2,4-trimethylbenzene (EXP)

1,2-dimethylhydrazine (ISO)

1-naphthyl isothiocyanate (EXP)

17alpha-ethynylestradiol (ISO)

17beta-estradiol (EXP)

2,2,2-tetramine (EXP)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

2,4,6-trinitrotoluene (EXP)

2,4-diaminotoluene (ISO)

2,4-dinitrotoluene (EXP)

2,6-dinitrotoluene (EXP)

2-amino-2-deoxy-D-glucopyranose (EXP)

2-amino-4,6-dinitrotoluene (EXP)

2-deoxy-D-glucose (EXP)

2-nitrofluorene (EXP)

3',5'-cyclic AMP (EXP)

3,4-dihydrocoumarin (ISO)

3-chloropropane-1,2-diol (EXP)

3-methyl-3H-imidazo[4,5-f]quinolin-2-amine (ISO)

3H-1,2-dithiole-3-thione (EXP)

4,4'-diaminodiphenylmethane (EXP,ISO)

4-(N-nitrosomethylamino)-1-(3-pyridyl)butan-1-one (EXP)

4-amino-2,6-dinitrotoluene (EXP)

acetamide (EXP)

aflatoxin B1 (EXP,ISO)

aldehydo-D-glucosamine (EXP)

aldehydo-D-glucose (EXP)

aldehydo-D-ribose (EXP)

all-trans-retinoic acid (ISO)

alpha-D-galactose (EXP)

ammonium chloride (EXP)

amphetamine (EXP)

aristolochic acid A (ISO)

Aroclor 1254 (EXP)

bacitracin (EXP)

benzatropine (ISO)

benzene (EXP)

benzo[a]pyrene (ISO)

beta-D-glucosamine (EXP)

bis(2-chloroethyl) sulfide (ISO)

bisphenol A (EXP,ISO)

bleomycin A2 (ISO)

Brodifacoum (EXP)

cadmium atom (ISO)

cadmium dichloride (EXP,ISO)

caffeine (ISO)

cannabidiol (ISO)

carbon nanotube (ISO)

CGP 52608 (ISO)

chloropicrin (ISO)

ciprofibrate (ISO)

cisplatin (EXP,ISO)

clofibrate (ISO)

clofibric acid (EXP)

cobalt dichloride (ISO)

copper atom (EXP,ISO)

copper(0) (EXP,ISO)

copper(II) sulfate (ISO)

corn oil (EXP)

coumarin (EXP)

crocidolite asbestos (ISO)

Cuprizon (ISO)

curcumin (EXP)

cyclosporin A (ISO)

D-glucitol (EXP)

D-glucose (EXP)

D-mannitol (EXP)

D-mannopyranose (EXP)

D-ribofuranose (EXP)

dibenzofurans (ISO)

dibutyl phthalate (ISO)

dicrotophos (ISO)

dihydroxyacetone (EXP)

diuron (EXP)

dorsomorphin (ISO)

doxorubicin (ISO)

entinostat (ISO)

epoxiconazole (ISO)

ethanol (EXP)

etoposide (ISO)

fenbuconazole (ISO)

fenthion (ISO)

fenvalerate (EXP)

fipronil (EXP)

flutamide (EXP)

folic acid (ISO)

fructose (EXP)

fumonisin B1 (ISO)

furan (EXP)

galactose (EXP)

gentamycin (EXP)

glafenine (EXP)

glucose (EXP)

glycerol (EXP)

haloperidol (ISO)

hydrogen peroxide (ISO)

indole-3-methanol (EXP)

inositol (EXP)

irinotecan (EXP)

ivermectin (ISO)

lead(0) (ISO)

leflunomide (EXP)

Licochalcone B (ISO)

lovastatin (ISO)

MeIQ (ISO)

MeIQx (ISO)

menadione (ISO)

metacetamol (ISO)

metformin (EXP)

methidathion (ISO)

methotrexate (ISO)

methylseleninic acid (ISO)

mono(2-ethylhexyl) phthalate (ISO)

Muraglitazar (EXP)

N-methyl-4-phenylpyridinium (ISO)

N-nitrosodiethylamine (EXP,ISO)

N-nitrosodimethylamine (EXP)

N-nitrosomorpholine (EXP)

nefazodone (EXP)

nimesulide (EXP)

Nonylphenol (EXP)

ochratoxin A (EXP,ISO)

orphenadrine (EXP)

p-toluidine (EXP)

paclitaxel (EXP)

panobinostat (ISO)

paracetamol (EXP,ISO)

perfluorooctanoic acid (EXP,ISO)

phenformin (EXP)

phenobarbital (EXP,ISO)

PhIP (ISO)

piperonyl butoxide (EXP)

pirinixic acid (EXP,ISO)

potassium dichromate (EXP)

pregnenolone 16alpha-carbonitrile (EXP,ISO)

propiconazole (ISO)

resveratrol (ISO)

rhamnose (EXP)

rotenone (EXP)

SB 431542 (ISO)

sodium arsenite (ISO)

sodium dichromate (EXP)

sorbose (EXP)

streptozocin (EXP)

sulfasalazine (ISO)

sunitinib (ISO)

T-2 toxin (EXP)

tamoxifen (ISO)

tanespimycin (ISO)

teriflunomide (ISO)

Tesaglitazar (EXP)

tetrachloroethene (ISO)

tetrachloromethane (EXP,ISO)

thapsigargin (EXP,ISO)

thioacetamide (EXP,ISO)

trichloroethene (EXP)

trichostatin A (ISO)

triphenyl phosphate (EXP)

triptonide (ISO)

troglitazone (ISO)

tunicamycin (ISO)

undecane (EXP)

uranium atom (ISO)

urethane (ISO)

valdecoxib (EXP)

valproic acid (ISO)

vancomycin (EXP)

vorinostat (ISO)

warfarin (ISO)

xylitol (EXP)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

arginine catabolic process to glutamate (IBA)

arginine catabolic process to proline via ornithine (IBA)

L-proline biosynthetic process (IEA)

ornithine metabolic process (TAS)

Cellular Component

cytoplasm (IBA)

mitochondrial matrix (ISO,ISS)

mitochondrion (ISO)

nucleoplasm (IEA,ISO)

Molecular Function

identical protein binding (IBA,ISO,ISS)

N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity (TAS)

ornithine aminotransferase activity (IBA,ISO,ISS)

protein binding (ISO)

pyridoxal phosphate binding (IBA)

Molecular Pathway Annotations Click to see Annotation Detail View

AGAT deficiency pathway (ISO)

arginine and proline metabolic pathway (IEA,ISO)

guanidinoacetate methyltransferase deficiency pathway (ISO)

gyrate atrophy pathway (ISO)

hyperprolinemia type I pathway (ISO)

hyperprolinemia type II pathway (ISO)

ornithine translocase deficiency pathway (ISO)

prolidase deficiency pathway (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	Rat ISS GO annotations from GOA human gene data--August 2006	GOA data from the GO Consortium
3.	KEGG: Kyoto Encyclopedia of Genes and Genomes	KEGG
4.	Ornithine metabolism in male and female rat kidney: mitochondrial expression of ornithine aminotransferase and arginase II.	Levillain O, etal., Am J Physiol Renal Physiol 2004 Apr;286(4):F727-38. Epub 2004 Feb 10.
5.	Rat ISS GO annotations from MGI mouse gene data--August 2006	MGD data from the GO Consortium
6.	An initiator codon mutation in ornithine-delta-aminotransferase causing gyrate atrophy of the choroid and retina.	Mitchell GA, etal., J Clin Invest. 1988 Feb;81(2):630-3.
7.	Sequence of the precursor to rat ornithine aminotransferase deduced from a cDNA clone.	Mueckler MM and Pitot HC, J Biol Chem 1985 Oct 25;260(24):12993-7.
8.	Electronic Transfer of LocusLink and RefSeq Data	NCBI rat LocusLink and RefSeq merged data July 26, 2002
9.	OMIM Disease Annotation Pipeline	OMIM Disease Annotation Pipeline
10.	KEGG Annotation Import Pipeline	Pipeline to import KEGG annotations from KEGG into RGD
11.	SMPDB Annotation Import Pipeline	Pipeline to import SMPDB annotations from SMPDB into RGD
12.	GOA pipeline	RGD automated data pipeline
13.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
14.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
15.	Isolation and characterization of the rat gene encoding ornithine aminotransferase.	Shull JD, etal., Biochim Biophys Acta 1992 Sep 24;1132(2):214-8.
16.	Cell-type specific interactions between retinoic acid and thyroid hormone in the regulation of expression of the gene encoding ornithine aminotransferase.	Shull JD, etal., Endocrinology 1995 May;136(5):2120-6.
17.	The ornithine aminotransferase-encoding gene family of rat: cloning, characterization, and evolutionary relationships between a single expressed gene and three pseudogenes.	Shull JD, etal., Gene 1991 Aug 15;104(2):203-9.
18.	Promoter region of the rat gene encoding ornithine aminotransferase: transcriptional activity, sequence, and DNase-I-hypersensitive sites.	Shull JD, etal., Gene 1993 Mar 30;125(2):169-75.
19.	Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.	Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.

Additional References at PubMed

PMID:2229004	PMID:3170546	PMID:6819292	PMID:9514741	PMID:14651853	PMID:15489334	PMID:18614015	PMID:23076989	PMID:23106098	PMID:23656379

Genomics

Comparative Map Data

Oat
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mRatBN7.2	1	187,347,862 - 187,367,644 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	1	187,347,865 - 187,367,682 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	1	195,698,027 - 195,717,805 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	1	202,876,939 - 202,896,719 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	1	195,550,072 - 195,569,851 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	1	204,562,289 - 204,582,070 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	1	204,562,289 - 204,582,070 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	1	211,555,927 - 211,575,708 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	1	192,026,623 - 192,046,404 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	1	192,176,503 - 192,196,285 (-)	NCBI
Celera	1	185,092,131 - 185,111,563 (-)	NCBI		Celera
Cytogenetic Map	1	q41	NCBI

OAT
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	10	124,397,303 - 124,418,923 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	10	124,397,303 - 124,418,976 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	10	126,085,872 - 126,107,492 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	10	126,075,862 - 126,097,441 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	10	126,075,861 - 126,097,450	NCBI
Celera	10	119,858,073 - 119,879,754 (-)	NCBI		Celera
Cytogenetic Map	10	q26.13	NCBI
HuRef	10	119,770,641 - 119,792,323 (-)	NCBI		HuRef
CHM1_1	10	126,367,759 - 126,389,447 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	10	125,275,480 - 125,297,100 (-)	NCBI		T2T-CHM13v2.0

Oat
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	7	132,159,204 - 132,178,127 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	7	132,159,207 - 132,178,127 (-)	Ensembl		GRCm39 Ensembl
GRCm38	7	132,557,475 - 132,576,398 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	7	132,557,478 - 132,576,398 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	7	139,749,158 - 139,768,081 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	7	132,395,822 - 132,408,481 (-)	NCBI		MGSCv36	mm8
Celera	7	132,362,445 - 132,381,370 (-)	NCBI		Celera
Cytogenetic Map	7	F3	NCBI
cM Map	7	76.3	NCBI

Oat
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955477	2,429,776 - 2,450,624 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955477	2,430,146 - 2,450,135 (-)	NCBI	ChiLan1.0	ChiLan1.0

OAT
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1	10	136,248,355 - 136,271,017 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	10	120,955,805 - 120,977,484 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	10	125,224,032 - 125,245,530 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	10	125,224,032 - 125,245,504 (-)	Ensembl	panpan1.1		panPan2

OAT
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	28	33,763,661 - 33,788,817 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	28	33,758,473 - 33,788,759 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	28	33,826,851 - 33,851,641 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	28	34,320,605 - 34,345,627 (-)	NCBI		ROS_Cfam_1.0
UU_Cfam_GSD_1.0	28	34,120,928 - 34,145,786 (-)	NCBI		UU_Cfam_GSD_1.0

Oat
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024407213	12,817,898 - 12,836,941 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936486	12,723,305 - 12,743,422 (-)	Ensembl	SpeTri2.0
SpeTri2.0	NW_004936486	12,723,363 - 12,743,367 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

OAT
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1	14	133,808,193 - 133,830,517 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	14	145,318,779 - 145,341,064 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

OAT
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	9	117,060,819 - 117,083,160 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	9	117,060,393 - 117,083,126 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666048	78,377,280 - 78,399,645 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Oat
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624737	22,664,129 - 22,678,535 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624737	22,657,158 - 22,679,213 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in Oat
73 total Variants

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	96
Count of miRNA genes:	83
Interacting mature miRNAs:	91
Transcripts:	ENSRNOT00000022628
Prediction methods:	Miranda, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (mRatBN7.2)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
10059597	Bp377	Blood pressure QTL 377	3.42	0.025	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	32737458	199368955	Rat
634314	Niddm44	Non-insulin dependent diabetes mellitus QTL 44			blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	1	49393289	199050459	Rat
1578780	Cm52	Cardiac mass QTL 52	3.3	0.0001	heart mass (VT:0007028)	heart wet weight (CMO:0000069)	1	81591954	219808434	Rat
1331749	Hrtrt11	Heart rate QTL 11	2.973		heart pumping trait (VT:2000009)	heart rate (CMO:0000002)	1	94494440	198211706	Rat
70209	Niddm23	Non-insulin dependent diabetes mellitus QTL 23	2.82		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	1	94494440	198324465	Rat
731168	Bp154	Blood pressure QTL 154	3.4		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	94642644	214537671	Rat
1354591	Cm36	Cardiac mass QTL 36	4.1		heart left ventricle mass (VT:0007031)	calculated heart weight (CMO:0000073)	1	102813953	201278233	Rat
1354615	Cm32	Cardiac mass QTL 32	5.2		heart left ventricle mass (VT:0007031)	heart left ventricle wet weight (CMO:0000071)	1	102813953	201278233	Rat
1354606	Bp246	Blood pressure QTL 246	3.6		arterial blood pressure trait (VT:2000000)	pulse pressure (CMO:0000292)	1	102813953	218753816	Rat
7794788	Mcs32	Mammary carcinoma susceptibility QTL 32	2.61		mammary gland integrity trait (VT:0010552)	mammary tumor incidence/prevalence measurement (CMO:0000946)	1	115540693	238914717	Rat
7421630	Bp362	Blood pressure QTL 362		0.001	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	1	118608292	241799120	Rat
631205	Bp196	Blood pressure QTL 196	4	0.0001	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	1	118944897	199050459	Rat
631549	Bp89	Blood pressure QTL 89	5.7		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	123350581	201284552	Rat
1598853	Memor3	Memory QTL 3	4.5		exploratory behavior trait (VT:0010471)	total horizontal distance resulting from voluntary locomotion in an experimental apparatus (CMO:0001443)	1	143506580	212458660	Rat
61348	Bp30	Blood pressure QTL 30	2.4		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	144017057	197814409	Rat
70160	Bw18	Body weight QTL 18	5.7		body mass (VT:0001259)	body weight (CMO:0000012)	1	144267353	196383668	Rat
737828	Hcas3	Hepatocarcinoma susceptibility QTL 3	4.9		liver integrity trait (VT:0010547)	liver tumorous lesion volume to total liver volume ratio (CMO:0001082)	1	144267353	222987745	Rat
2302378	Insul11	Insulin level QTL 11	3.25		blood insulin amount (VT:0001560)	serum insulin level (CMO:0000358)	1	144267353	251128347	Rat
7771612	Cm80	Cardiac mass QTL 80	8.4		heart left ventricle mass (VT:0007031)	heart left ventricle weight (CMO:0000776)	1	149448574	221264292	Rat
724531	Uae5	Urinary albumin excretion QTL 5	4		urine albumin amount (VT:0002871)	urine albumin level (CMO:0000130)	1	150700142	252085212	Rat
1578759	Uae30	Urinary albumin excretion QTL 30	3.3	0.003	urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	1	150700247	252085048	Rat
1578778	Pur4	Proteinuria QTL 4	3.3	0.003	urine total protein amount (VT:0000032)	urine total protein excretion rate (CMO:0000756)	1	150700247	252085048	Rat
1354602	Bw35	Body weight QTL 35	12.2		body mass (VT:0001259)	body weight (CMO:0000012)	1	151162512	201278233	Rat
1354620	Kidm19	Kidney mass QTL 19	4		kidney mass (VT:0002707)	calculated kidney weight (CMO:0000160)	1	151162512	201278233	Rat
1354634	Kidm12	Kidney mass QTL 12	3.9		kidney mass (VT:0002707)	right kidney wet weight (CMO:0000082)	1	151162512	201278233	Rat
1354636	Lmblg1	Limb length QTL 1	6.4		tibia length (VT:0004357)	tibia length (CMO:0000450)	1	151162512	201278233	Rat
1354610	Bw34	Body weight QTL 34	4.1		body mass (VT:0001259)	body weight (CMO:0000012)	1	151162512	256448636	Rat
1354646	Kidm18	Kidney mass QTL 18	5.7		kidney mass (VT:0002707)	calculated kidney weight (CMO:0000160)	1	151162512	256448636	Rat
1354661	Bw33	Body weight QTL 33	5.2		body mass (VT:0001259)	body weight (CMO:0000012)	1	151162512	256448636	Rat
1358886	Bp260	Blood pressure QTL 260	3.67		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	1	151162766	225824951	Rat
61343	Bp28	Blood pressure QTL 28			arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	151646613	196646613	Rat
1549837	Hcar15	Hepatocarcinoma resistance QTL 15		0.05	liver integrity trait (VT:0010547)	liver tumorous lesion number (CMO:0001068)	1	153136852	260522016	Rat
2303622	Vencon6	Ventilatory control QTL 6		0.001	respiration trait (VT:0001943)	respiration rate (CMO:0000289)	1	154561505	199561505	Rat
4889428	Stresp24	Stress response QTL 24		0.05	heart pumping trait (VT:2000009)	absolute change in electrocardiographic low frequency R-R spectral component to high frequency R-R spectral component ratio (CMO:0002162)	1	155866514	200866514	Rat
1354618	Kidm15	Kidney mass QTL 15	5		kidney mass (VT:0002707)	left kidney wet weight (CMO:0000083)	1	156677124	201278233	Rat
2312420	Pur17	Proteinuria QTL 17	7.1	0.0001	urine protein amount (VT:0005160)	urine total protein excretion rate (CMO:0000756)	1	156677124	218753816	Rat
1354580	Scort1	Serum corticosterone level QTL 1	3.4		blood corticosterone amount (VT:0005345)	blood corticosterone level (CMO:0001172)	1	156677124	256448636	Rat
61347	Bp197	Blood pressure QTL 197	4.2		arterial blood pressure trait (VT:2000000)	blood pressure measurement (CMO:0000003)	1	158633083	203633083	Rat
2292222	Bp307	Blood pressure QTL 307	3.06	0.0014	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	164310393	213533942	Rat
2292220	Bp306	Blood pressure QTL 306	3.47	0.00087	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	164310393	243914901	Rat
619613	Bp77	Blood pressure QTL 77		0.01	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	164747424	209747424	Rat
619613	Bp77	Blood pressure QTL 77		0.01	arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	1	164747424	209747424	Rat
2312558	Glom17	Glomerulus QTL 17	3.9	0.001	kidney glomerulus morphology trait (VT:0005325)	index of glomerular damage (CMO:0001135)	1	166532971	191278129	Rat
1354653	Despr9	Despair related QTL 9		0.00019	locomotor behavior trait (VT:0001392)	amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)	1	167909849	212909849	Rat
619614	Bp78	Blood pressure QTL 78		0.001	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	169112897	197261052	Rat
619614	Bp78	Blood pressure QTL 78		0.001	arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	1	169112897	197261052	Rat
61341	Bp26	Blood pressure QTL 26			arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	169537671	214537671	Rat
724562	Rends1	Renal damage susceptibility QTL 1		0.05	kidney glomerulus integrity trait (VT:0010546)	index of glomerular damage (CMO:0001135)	1	169537671	214537671	Rat
1358294	Bw37	Body weight QTL 37	5	0.000011	body mass (VT:0001259)	body weight (CMO:0000012)	1	171310381	216310381	Rat
2293689	Bss47	Bone structure and strength QTL 47	7.25	0.0001	lumbar vertebra size trait (VT:0010518)	lumbar vertebra trabecular cross-sectional area (CMO:0001692)	1	171629477	216629477	Rat
2293693	Bss22	Bone structure and strength QTL 22	33.52	0.0001	femur morphology trait (VT:0000559)	femur cross-sectional area (CMO:0001661)	1	171629477	216629477	Rat
2300161	Bmd43	Bone mineral density QTL 43	8.4	0.0001	femur mineral mass (VT:0010011)	volumetric bone mineral density (CMO:0001553)	1	171629477	216629477	Rat
2300174	Bmd42	Bone mineral density QTL 42	8.4	0.0001	lumbar vertebra mineral mass (VT:0010511)	bone mineral density (CMO:0001226)	1	171629477	216629477	Rat
2300187	Bmd41	Bone mineral density QTL 41	8.9	0.0001	femur mineral mass (VT:0010011)	volumetric bone mineral density (CMO:0001553)	1	171629477	216629477	Rat
2293654	Bss30	Bone structure and strength QTL 30	32.65	0.0001	femur strength trait (VT:0010010)	femur midshaft polar moment of inertia (CMO:0001669)	1	171629477	216629477	Rat
2293673	Bss27	Bone structure and strength QTL 27	18.63	0.0001	femur morphology trait (VT:0000559)	femur midshaft cortical cross-sectional area (CMO:0001663)	1	171629477	216629477	Rat
2293677	Bss41	Bone structure and strength QTL 41	9.38	0.0001	lumbar vertebra size trait (VT:0010518)	lumbar vertebra cross-sectional area (CMO:0001689)	1	171629477	216629477	Rat
1549830	Bss1	Bone structure and strength QTL 1	4.8		femur strength trait (VT:0010010)	femur ultimate force (CMO:0001675)	1	172609619	217609619	Rat
631214	Bw61	Body weight QTL61	3.4	0.0001	intramuscular adipose amount (VT:0010044)	intramuscular fat area (CMO:0001162)	1	173108781	218108781	Rat
631670	Iddm10	Insulin dependent diabetes mellitus QTL 10	1.9		blood glucose amount (VT:0000188)	plasma glucose level (CMO:0000042)	1	174133260	196383668	Rat
70163	Bw20	Body weight QTL 20	5.1		body mass (VT:0001259)	body weight (CMO:0000012)	1	174133260	219133260	Rat
738032	Hcas5	Hepatocarcinoma susceptibility QTL 5	3.12		liver integrity trait (VT:0010547)	liver tumorous lesion number (CMO:0001068)	1	176426412	257976495	Rat
1600380	Niddm70	Non-insulin dependent diabetes mellitus QTL 70	3.1	0.0008	blood insulin amount (VT:0001560)	plasma insulin level (CMO:0000342)	1	176550523	221550523	Rat
10059600	Bp378	Blood pressure QTL 378	3.08	0.05	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	176869060	221869060	Rat
1354624	Cm35	Cardiac mass QTL35	5.7		heart left ventricle mass (VT:0007031)	calculated heart weight (CMO:0000073)	1	177227632	256448636	Rat
1354652	Kidm20	Kidney mass QTL 20	4.3		kidney mass (VT:0002707)	calculated kidney weight (CMO:0000160)	1	177227632	256448636	Rat
1558658	Bw59	Body weight QTL 59	3.5	0.0003	body mass (VT:0001259)	body weight (CMO:0000012)	1	178784622	223784622	Rat
2325725	Eae31	Experimental allergic encephalomyelitis QTL 31			nervous system integrity trait (VT:0010566)	experimental autoimmune encephalomyelitis severity score (CMO:0001419)	1	178810256	188377506	Rat
634321	Hc1	Hypercalciuria QTL 1	2.91		urine calcium amount (VT:0002985)	urine calcium excretion rate (CMO:0000763)	1	178810256	240830002	Rat
1578763	Kidm29	Kidney mass QTL 29	3.3	0.0001	kidney mass (VT:0002707)	both kidneys wet weight (CMO:0000085)	1	179567751	260522016	Rat
1302787	Stl25	Serum triglyceride level QTL 25	2.7	0.0073	blood triglyceride amount (VT:0002644)	plasma triglyceride level (CMO:0000548)	1	180359209	210702199	Rat
6903303	Scl34	Serum cholesterol QTL 34	2.5	0.0033	blood cholesterol amount (VT:0000180)	plasma total cholesterol level (CMO:0000585)	1	180359209	218108781	Rat
737977	Bp160	Blood pressure QTL 160		0.001	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	1	181133855	226133855	Rat
61378	Bp43	Blood pressure QTL 43	22.6		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	181746937	196383668	Rat
724559	Pancm1	Pancreatic morphology QTL 1	7.1		islet of Langerhans morphology trait (VT:0005215)	pancreatic islet damage composite score (CMO:0001156)	1	181759564	214537555	Rat
2293083	Iddm25	Insulin dependent diabetes mellitus QTL 25	4.18		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	1	181829673	224569684	Rat
634312	Bp143	Blood pressure QTL 143	3	0.0002	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	182623426	219932796	Rat
8655655	Arrd2	Age-related retinal degeneration QTL 2	7.79		retinal layer morphology trait (VT:0003727)	percentage of study population developing retinopathy during a period of time (CMO:0002453)	1	183970203	243914901	Rat
8655855	Arrd3	Age-related retinal degeneration QTL 3	3.07		lens clarity trait (VT:0001304)	cataract incidence/prevalence measurement (CMO:0001585)	1	183970203	243914901	Rat
631838	Niddm36	Non-insulin dependent diabetes mellitus QTL 36		0.01	insulin secretion trait (VT:0003564)	calculated pancreatic islet insulin release measurement (CMO:0001217)	1	184550676	229550676	Rat
1300145	Rf7	Renal function QTL 7	2.96		urine creatinine amount (VT:0010540)	urine creatinine level (CMO:0000125)	1	185145134	221264292	Rat
1359018	Hrtrt20	Heart rate QTL 20	3.08		heart pumping trait (VT:2000009)	heart rate (CMO:0000002)	1	185356336	202902618	Rat
2312564	Glom18	Glomerulus QTL 18	2.4	0.003	kidney glomerulus morphology trait (VT:0005325)	index of glomerular damage (CMO:0001135)	1	185356336	231689108	Rat

Markers in Region

RH139534

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	1	187,352,792 - 187,352,983 (+)	MAPPER	mRatBN7.2
Rnor_6.0	1	204,567,220 - 204,567,410	NCBI	Rnor6.0
Rnor_5.0	1	211,560,858 - 211,561,048	UniSTS	Rnor5.0
RGSC_v3.4	1	192,031,554 - 192,031,744	UniSTS	RGSC3.4
Celera	1	185,097,062 - 185,097,252	UniSTS
Cytogenetic Map	1	q41	UniSTS

RH127469

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	1	187,348,354 - 187,348,551 (+)	MAPPER	mRatBN7.2
Rnor_6.0	1	204,562,782 - 204,562,978	NCBI	Rnor6.0
Rnor_5.0	1	211,556,420 - 211,556,616	UniSTS	Rnor5.0
RGSC_v3.4	1	192,027,116 - 192,027,312	UniSTS	RGSC3.4
Celera	1	185,092,624 - 185,092,820	UniSTS
Cytogenetic Map	1	q41	UniSTS

D1Bda37

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	1	187,348,178 - 187,348,548 (+)	MAPPER	mRatBN7.2
Rnor_6.0	1	204,562,606 - 204,562,975	NCBI	Rnor6.0
Rnor_5.0	1	211,556,244 - 211,556,613	UniSTS	Rnor5.0
RGSC_v3.4	1	192,026,940 - 192,027,309	UniSTS	RGSC3.4
Celera	1	185,092,448 - 185,092,817	UniSTS
Cytogenetic Map	1	q41	UniSTS

RH140369

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	1	187,352,827 - 187,352,984 (+)	MAPPER	mRatBN7.2
Rnor_6.0	1	204,567,255 - 204,567,411	NCBI	Rnor6.0
Rnor_5.0	1	211,560,893 - 211,561,049	UniSTS	Rnor5.0
RGSC_v3.4	1	192,031,589 - 192,031,745	UniSTS	RGSC3.4
Celera	1	185,097,097 - 185,097,253	UniSTS
RH 3.4 Map	1	1432.7	UniSTS
Cytogenetic Map	1	q41	UniSTS

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

	alimentary part of gastrointestinal system	circulatory system	endocrine system	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	appendage
High										7
Medium	3	43	57	41	19	41	8	11	74	28	40	11	8
Low											1
Below cutoff

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_022521	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AH002248	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC061551	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH473953	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ210816	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ216487	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ223550	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JACYVU010000044	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	M11842	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSRNOT00000022628 ⟹ ENSRNOP00000022628

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	1	187,347,865 - 187,367,682 (-)	Ensembl
Rnor_6.0 Ensembl	1	204,562,289 - 204,582,070 (-)	Ensembl

RefSeq Acc Id:

NM_022521 ⟹ NP_071966

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	1	187,347,862 - 187,367,644 (-)	NCBI
Rnor_6.0	1	204,562,289 - 204,582,070 (-)	NCBI
Rnor_5.0	1	211,555,927 - 211,575,708 (-)	NCBI
RGSC_v3.4	1	192,026,623 - 192,046,404 (-)	RGD
Celera	1	185,092,131 - 185,111,563 (-)	RGD

Sequence:

show sequence

GACGCGCCGGGCTGCCACATCGGGCTTCGTGGCTGAAATACAGTCAGTGTCGCTTAGCGGACGC
TGTCAGGTCTCTCTGCACTTCCATTCCTGAAGGACCCACACAATGCTTTCCAAACTAGCAAGTC
TGCAGACTGTTGCCGCTCTGCGTCGAGGACTCCGCACCTCAGTCGCCTCTGCCACATCTGTTGC
AACGAAGAAGACAGAGCAAGGCCCACCATCCTCTGAGTACATTTTTGAACGGGAATCTAAATAT
GGTGCACACAATTACCATCCTTTACCTGTAGCCCTGGAGAGAGGAAAAGGCATTTATATGTGGG
ATGTGGAAGGCAGGCAGTACTTCGACTTCCTGAGTGCTTATGGTGCTGTCAGCCAAGGACACTG
CCACCCAAAGATCATAGAAGCCATGAAGAGTCAGGTGGACAAGCTGACATTAACATCTCGGGCT
TTCTATAACAATGTCCTTGGTGAATATGAGGAGTACATCACCAAGCTTTTCAACTACAACAAAG
TTCTTCCTATGAATACAGGAGTGGAGGCCGGAGAGACTGCGTGTAAGCTTGCTCGCCGTTGGGG
CTACACCGTGAAAGGCATCCAGAAATACAAAGCAAAGATCGTTTTTGCTGTTGGAAACTTTTGG
GGTCGGACGCTGTCTGCAGTCTCCAGTTCCACAGATCCGACCAGTTATGATGGCTTTGGACCCT
TCATGCCAGGCTTTGAAACCATCCCATATAACGATCTGCCTGCGCTAGAGCGTGCTCTTCAGGA
TCCCAATGTTGCTGCTTTCATGGTGGAGCCCATCCAGGGTGAAGCGGGTGTTATCGTTCCAGAT
CCAGGATACCTGACGGGAGTTCGAGAACTTTGCACCCGGCACCAGGTCCTGTTTATTGCTGATG
AAATACAGACAGGATTGGCTAGAACTGGTCGATGGCTAGCTGTGGATCATGAGAATGTCAGACC
TGACATAGTTCTTCTTGGGAAGGCCCTTTCTGGTGGCTTATATCCCGTGTCTGCAGTGCTGTGT
GATGATGACATAATGCTGACCATTAAACCAGGCGAGCACGGCTCCACGTATGGCGGCAACCCAC
TAGGCTGCCGAATTGCTATTGCGGCTCTTGAGGTTTTAGAAGAAGAGCATCTTGCTGAAAACGC
AGACAAGATGGGTGCCATCTTGAGAAAGGAGCTCATGAAGCTGCCATCTGATGTTGTGACTGCT
GTGAGAGGGAAAGGGTTGCTAAATGCCATCGTCATCCGAGAAACCAAAGATTGTGACGCTTGGA
AGGTGTGCCTGCGACTCCGAGATAATGGGCTTCTGGCCAAGCCAACCCATGGTGATATCATCCG
GCTTGCCCCTCCACTTGTGATCAAAGAGGATGAGATCCGGGAGTCAGTGGAGATCATCAACAAG
ACCATCTTGTCCTTCTGAGAGTAGGAACTCTGGGGAGCCATCTTCAGATGGGGCTCTTGTGAAA
CTCTGCTTGGGATGGGCAGATTCGGCTTGTCTGTCTCCTAAAAGACAATTTTTTGAATATGTAT
TATATATTTCAGTTGATGCATAGTGGAGTGACACCTAGGAACCTGCAGGTGGCTGCGTGACACA
AGAGTGAGAGCGAGAGGCATCTCTTTGTTAAAGTTTGACTGTGTGGGAGCTTTCTAAGGAGAAA
CAGATCTATCTGCATACAGCCTGCAGAGTCCTGCCGTAATTTACATGTGTCTTTACATCTTCCT
TGCTGGCATGAATGTTTTGTATTTGGAAGTTTTTTTCTGAGATACTACATAAGAAACTGTTGAA
TCATTATAATCAATGAATGGTAAGATGATTGAGGGTTGAGCATATGTAAAATACTAGTTTAAAG
TACACTTTGCATTGGCCAACAGCAGAATGTATTATATAGTTTCTGAGAATTCATTACCAAATTA
TACTTTAAGTGCTTGATTGCAATTTGTAAAACATTTATTTTCAGTATTTCTTTGAATAAAGCTT
CATTTTTCTTTATACCCCAAAAGAGTATTTTGTATTTATCTTTTGGTAATAATCAGTGTATTAT
TTCACCCCTATGACTGGCATTTCATCCCCTATTGAGATCACTGGGTGTGTTTCAGGCTTTTTAT
TCTAAATAAAGCTATGACCAGTTCATATCTGTACAGAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AA

hide sequence

Protein Sequences


Protein RefSeqs	NP_071966	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAA41766	(Get FASTA)	NCBI Sequence Viewer
	AAA42060	(Get FASTA)	NCBI Sequence Viewer
	AAA42061	(Get FASTA)	NCBI Sequence Viewer
	AAH61551	(Get FASTA)	NCBI Sequence Viewer
	EDM11717	(Get FASTA)	NCBI Sequence Viewer
	EDM11718	(Get FASTA)	NCBI Sequence Viewer
	EDM11719	(Get FASTA)	NCBI Sequence Viewer
	EDM11720	(Get FASTA)	NCBI Sequence Viewer
	EDM11721	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000022628
GenBank Protein	P04182	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:	NP_071966 ⟸ NM_022521
- Peptide Label:	precursor
- UniProtKB:	Q6LDF6 (UniProtKB/Swiss-Prot), Q6LDF7 (UniProtKB/Swiss-Prot), P04182 (UniProtKB/Swiss-Prot), A6HWY7 (UniProtKB/TrEMBL)
- Sequence:	show sequence MLSKLASLQTVAALRRGLRTSVASATSVATKKTEQGPPSSEYIFERESKYGAHNYHPLPVALER GKGIYMWDVEGRQYFDFLSAYGAVSQGHCHPKIIEAMKSQVDKLTLTSRAFYNNVLGEYEEYIT KLFNYNKVLPMNTGVEAGETACKLARRWGYTVKGIQKYKAKIVFAVGNFWGRTLSAVSSSTDPT SYDGFGPFMPGFETIPYNDLPALERALQDPNVAAFMVEPIQGEAGVIVPDPGYLTGVRELCTRH QVLFIADEIQTGLARTGRWLAVDHENVRPDIVLLGKALSGGLYPVSAVLCDDDIMLTIKPGEHG STYGGNPLGCRIAIAALEVLEEEHLAENADKMGAILRKELMKLPSDVVTAVRGKGLLNAIVIRE TKDCDAWKVCLRLRDNGLLAKPTHGDIIRLAPPLVIKEDEIRESVEIINKTILSF hide sequence

RefSeq Acc Id:

ENSRNOP00000022628 ⟸ ENSRNOT00000022628

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-P04182-F1-model_v2	AlphaFold	P04182	1-439	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

6849756

Promoter ID:

EP37015

Type:

single initiation site

Name:

RN_OAT

Description:

Ornithine aminotransferase, OAT gene.

SO ACC ID:

SO:0000170

Source:

EPD (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Notes:

homology_group=Homology group 215; Mammalalian ornithine aminotransferase

Experiment Methods:

RNA sequencing by primer extension

Regulation:

most tissues; (modulated by) hormones

Position:

Rat Assembly	Chr	Position (strand)	Source
RGSC_v3.4	1	192,046,386 - 192,046,446	EPD

RGD ID:

13690483

Promoter ID:

EPDNEW_R1008

Type:

initiation region

Name:

Oat_1

Description:

ornithine aminotransferase

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	1	204,582,053 - 204,582,113	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:621724	AgrOrtholog
BioCyc Gene	G2FUF-57212	BioCyc
BioCyc Pathway	ARG-PRO-PWY [L-arginine degradation VI (arginase 2 pathway)]	BioCyc
	ARGASEDEG-PWY [L-arginine degradation I (arginase pathway)]	BioCyc
	CITRULBIO-PWY [L-citrulline biosynthesis]	BioCyc
Ensembl Genes	ENSRNOG00000016807	Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript	ENSRNOT00000022628	ENTREZGENE, UniProtKB/Swiss-Prot
Gene3D-CATH	3.40.640.10	UniProtKB/Swiss-Prot
	3.90.1150.10	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Type I PLP-dependent aspartate aminotransferase-like (Major domain)	UniProtKB/TrEMBL
IMAGE_CLONE	IMAGE:6890520	IMAGE-MGC_LOAD
InterPro	Aminotrans_3	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Orn_aminotrans	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	PyrdxlP-dep_Trfase	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	PyrdxlP-dep_Trfase_dom1	UniProtKB/Swiss-Prot
	PyrdxlP-dep_Trfase_major	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	PyrdxlP-dep_Trfase_small	UniProtKB/TrEMBL
KEGG Report	rno:64313	UniProtKB/Swiss-Prot
MGC_CLONE	MGC:72829	IMAGE-MGC_LOAD
NCBI Gene	64313	ENTREZGENE
PANTHER	AMINOTRANSFERASE CLASS III	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	ORNITHINE AMINOTRANSFERASE, MITOCHONDRIAL	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam	Aminotran_3	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen	Oat	PhenoGen
PIRSF	Transaminase_4ab_Lys_Orn	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE	AA_TRANSFER_CLASS_3	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
RatGTEx	ENSRNOG00000016807	RatGTEx
Superfamily-SCOP	PLP-dependent transferases	UniProtKB/TrEMBL, UniProtKB/Swiss-Prot
UniProt	A6HWY6_RAT	UniProtKB/TrEMBL
	A6HWY7	ENTREZGENE, UniProtKB/TrEMBL
	A6HWY9_RAT	UniProtKB/TrEMBL
	OAT_RAT	UniProtKB/Swiss-Prot, ENTREZGENE
	Q6LDF6	ENTREZGENE
	Q6LDF7	ENTREZGENE
UniProt Secondary	Q6LDF6	UniProtKB/Swiss-Prot
	Q6LDF7	UniProtKB/Swiss-Prot

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2011-08-02	Oat	ornithine aminotransferase	Oat	ornithine aminotransferase (gyrate atrophy)	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2008-09-09	Oat	ornithine aminotransferase (gyrate atrophy)	Oat	ornithine aminotransferase	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2005-01-20	Oat	ornithine aminotransferase			Symbol and Name status set to approved	1299863	APPROVED
2002-08-07	Oat				Symbol and Name status set to provisional	70820	PROVISIONAL

RGD Curation Notes

Note Type	Note	Reference
gene_expression	expressed in liver and kidney	1358948
gene_protein	439 amino acid residues with a molecular weight of 48,332	633396
gene_regulation	mRNA expression is differentially regulated by retinoic acid and T3	1358948

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InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

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MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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