Hras (HRas proto-oncogene, GTPase) - Rat Genome Database

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Gene: Hras (HRas proto-oncogene, GTPase) Rattus norvegicus
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Symbol: Hras
Name: HRas proto-oncogene, GTPase
RGD ID: 2827
Description: Predicted to enable GTPase activity; guanyl ribonucleotide binding activity; and protein C-terminus binding activity. Involved in several processes, including cellular senescence; positive regulation of DNA replication; and positive regulation of ERK1 and ERK2 cascade. Acts upstream of or within positive regulation of Ras protein signal transduction. Located in intracellular membrane-bounded organelle and plasma membrane. Used to study diabetic retinopathy and liver carcinoma. Human ortholog(s) of this gene implicated in several diseases, including Costello syndrome; autistic disorder; carcinoma (multiple); epidermal nevus; and large congenital melanocytic nevus. Orthologous to human HRAS (HRas proto-oncogene, GTPase); PARTICIPATES IN adenosine signaling pathway; endothelin signaling pathway; ephrin - ephrin receptor bidirectional signaling axis; INTERACTS WITH (S)-nicotine; 1,2-dichlorobenzene; 1-naphthyl isothiocyanate.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: c-H-ras; GTPase HRas; H-Ras-1; Harvey ras1 protein; Harvey rat sarcoma viral (v-Ha-ras) oncogene homolog; Harvey rat sarcoma virus oncogene; HRAS1; p21ras; transforming protein p21
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21196,290,127 - 196,299,823 (-)NCBImRatBN7.2
mRatBN7.2 Ensembl1196,296,263 - 196,300,615 (-)Ensembl
Rnor_6.01214,178,404 - 214,181,841 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1214,178,407 - 214,181,686 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01221,095,943 - 221,099,362 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41201,385,705 - 201,388,987 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11201,540,000 - 201,542,640 (-)NCBI
Celera1193,930,281 - 193,933,583 (-)NCBICelera
RH 3.4 Map11437.21RGD
Cytogenetic Map1q41NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View
acute myeloid leukemia  (ISO)
adenoid cystic carcinoma  (ISO)
adult hepatocellular carcinoma  (ISO)
Alzheimer's disease  (ISO)
angiosarcoma  (ISO)
Animal Mammary Neoplasms  (ISO)
autistic disorder  (ISO)
autoimmune hepatitis  (ISO)
B-Cell Chronic Lymphocytic Leukemia  (ISO)
bladder carcinoma  (ISO)
bladder urothelial carcinoma  (ISO)
Brain Neoplasms  (ISO)
Breast Neoplasms  (ISO)
carcinoma  (ISO)
cardiofaciocutaneous syndrome  (ISO)
chronic lymphocytic leukemia  (ISO)
Colorectal Neoplasms  (ISO)
complex cortical dysplasia with other brain malformations  (ISO)
Congenital Myopathy with Excess of Muscle Spindles  (ISO)
Costello syndrome  (ISO)
developmental and epileptic encephalopathy  (ISO)
diabetic retinopathy  (IDA)
disease of cellular proliferation  (ISO)
Disease Progression  (ISO)
early infantile epileptic encephalopathy  (ISO)
endometrial carcinoma  (ISO)
epidermal nevus  (ISO)
esophageal carcinoma  (ISO)
Experimental Diabetes Mellitus  (IEP)
Experimental Liver Neoplasms  (ISO)
Experimental Neoplasms  (ISO)
Follicular Thyroid Cancer  (ISO)
gastric adenocarcinoma  (ISO)
genetic disease  (ISO)
glioblastoma  (ISO)
head and neck squamous cell carcinoma  (ISO)
hepatocellular adenoma  (ISO)
hepatocellular carcinoma  (ISO)
high grade glioma  (ISO)
Hydrops Fetalis  (ISO)
intellectual disability  (ISO)
large congenital melanocytic nevus  (ISO)
linear nevus sebaceous syndrome  (ISO)
liver cancer  (ISO)
liver carcinoma  (IDA)
liver cirrhosis  (ISO)
Liver Neoplasms  (ISO)
lung adenocarcinoma  (ISO)
Lung Neoplasms  (ISO)
lung non-small cell carcinoma  (ISO)
lung squamous cell carcinoma  (ISO)
malignant astrocytoma  (ISS)
Mammary Neoplasms, Experimental  (IAGP,ISO)
melanoma  (ISO)
Mouth Neoplasms  (IEP,ISO)
multiple myeloma  (ISO)
myelodysplastic syndrome  (ISO)
Nasopharyngeal Neoplasms  (ISO)
Neoplasm Invasiveness  (ISO)
Neoplastic Cell Transformation  (ISO)
Neoplastic Processes  (ISO)
neuroblastoma  (ISO)
neuronal ceroid lipofuscinosis  (ISO)
Noonan syndrome  (ISO)
Noonan syndrome 3  (ISO)
obsessive-compulsive disorder  (ISO)
Ovarian Neoplasms  (ISO)
ovarian serous cystadenocarcinoma  (ISO)
pancreatic adenocarcinoma  (ISO)
papillary renal cell carcinoma  (ISO)
papilloma  (ISO)
Paraproteinemias  (ISO)
Penile Neoplasms  (ISO)
phobic disorder  (ISO)
Pigmented Nevus  (ISO)
plasma cell neoplasm  (ISO)
plasmacytoma  (ISO)
pre-malignant neoplasm  (ISO)
prostate adenocarcinoma  (ISO)
Prostatic Neoplasms  (ISO)
pulmonary valve stenosis  (ISO)
RASopathy  (ISO)
Recurrence  (ISO)
rhabdomyosarcoma  (ISO)
Sebaceous Nevus Syndrome and Hemimegalencephaly  (ISO)
seminoma  (ISO)
skin benign neoplasm  (ISO)
skin melanoma  (ISO)
Skin Neoplasms  (ISO)
spermatocytoma  (ISO)
Splenic Neoplasms  (ISO)
Sporadic Papillary Renal Cell Carcinoma  (ISO)
squamous cell carcinoma  (ISO)
Stomach Neoplasms  (ISO)
Supravalvar Aortic Stenosis, Eisenberg Type  (ISO)
supravalvular aortic stenosis  (ISO)
T-Cell Lymphoma  (ISO)
thymoma  (ISO)
thyroid gland follicular carcinoma  (ISO,ISS)
Thyroid Neoplasms  (ISO)
Tongue Neoplasms  (ISO)
transitional cell carcinoma  (ISO)
Trichilemmoma  (ISO)
urinary bladder cancer  (ISO)
Urinary Bladder Neoplasm  (ISO)
uterine cancer  (ISO)
uterine carcinosarcoma  (ISO)
Uterine Cervical Neoplasms  (ISO)

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-epicatechin-3-O-gallate  (ISO)
(-)-epigallocatechin 3-gallate  (ISO)
(S)-nicotine  (EXP,ISO)
1,2-dichlorobenzene  (EXP)
1,2-dichloroethane  (ISO)
1,2-dimethylhydrazine  (ISO)
1-Amino-2,4-dibromoanthraquinone  (ISO)
1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine  (ISO)
1-naphthyl isothiocyanate  (EXP)
1-nitropyrene  (EXP,ISO)
17alpha-ethynylestradiol  (ISO)
17beta-estradiol  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (ISO)
2,4-dinitrotoluene  (EXP)
2,6-di-tert-butyl-4-methylphenol  (EXP,ISO)
2,6-dinitrotoluene  (EXP)
2-acetamidofluorene  (EXP)
2-trans,6-trans,10-trans-geranylgeranyl diphosphate  (ISO)
2-trans,6-trans-farnesyl diphosphate  (ISO)
3-aminobenzamide  (ISO)
3-methyl-3H-imidazo[4,5-f]quinolin-2-amine  (EXP)
4-hydroperoxycyclophosphamide  (ISO)
4-hydroxyphenyl retinamide  (ISO)
4-nitrophenol  (ISO)
4-nitroquinoline N-oxide  (ISO)
4-octylphenol  (ISO)
5-aza-2'-deoxycytidine  (ISO)
5-fluorouracil  (ISO)
7,12-dimethyltetraphene  (ISO)
8-hydroxy-2'-deoxyguanosine  (ISO)
acrolein  (ISO)
acrylamide  (EXP)
actinomycin D  (ISO)
ADP  (ISO)
aflatoxin B1  (ISO)
aldehydo-D-glucose  (EXP)
alendronic acid  (ISO)
all-trans-retinoic acid  (ISO)
alpha-pinene  (ISO)
aristolochic acid  (EXP,ISO)
Aroclor 1254  (EXP)
arsane  (ISO)
arsenic atom  (ISO)
arsenous acid  (ISO)
aspartame  (ISO)
atrazine  (ISO)
benzene  (ISO)
benzo[a]pyrene  (EXP,ISO)
benzo[a]pyrene diol epoxide I  (ISO)
Benzo[a]pyrene-7,8-diol  (ISO)
benzo[c]phenanthrene  (ISO)
Benzoyl peroxide  (ISO)
beryllium atom  (EXP)
beryllium dihydride  (EXP)
beryllium(0)  (EXP)
biphenyl-2-ol  (ISO)
biphenyl-4-amine  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
bortezomib  (ISO)
buta-1,3-diene  (ISO)
cadmium dichloride  (ISO)
caffeine  (ISO)
capecitabine  (ISO)
capsaicin  (ISO)
carbamazepine  (ISO)
carbon nanotube  (ISO)
chloroprene  (ISO)
chromium(6+)  (ISO)
ciguatoxin CTX1B  (ISO)
cisplatin  (EXP,ISO)
copper atom  (ISO)
copper(0)  (ISO)
copper(II) sulfate  (ISO)
crocidolite asbestos  (ISO)
cyclosporin A  (ISO)
D-glucose  (EXP)
deoxycholic acid  (ISO)
dexamethasone  (ISO)
diarsenic trioxide  (ISO)
dibenzoylmethane  (ISO)
dichlorine  (EXP)
diclofenac  (ISO)
dimethyl sulfoxide  (ISO)
doxifluridine  (ISO)
doxorubicin  (ISO)
elemental selenium  (ISO)
ellagic acid  (ISO)
enzyme inhibitor  (ISO)
erastin  (ISO)
ethanol  (ISO)
ethyl methanesulfonate  (ISO)
eugenol  (ISO)
farnesol  (ISO)
farnesyl diphosphate  (ISO)
fenofibrate  (ISO)
finasteride  (EXP)
fipronil  (EXP)
flurbiprofen  (ISO)
flutamide  (EXP)
folic acid  (ISO)
formaldehyde  (EXP,ISO)
GDP  (ISO)
geraniol  (ISO)
glafenine  (EXP)
gliotoxin  (ISO)
glucaric acid  (ISO)
glucose  (EXP)
glutathione  (ISO)
glycyrrhetinate  (ISO)
glycyrrhetinic acid  (ISO)
Goe 6976  (ISO)
GTP  (ISO)
heptachlor  (ISO)
hydrogen peroxide  (ISO)
hydroquinone  (ISO)
iodoacetic acid  (ISO)
iron atom  (EXP)
iron(0)  (EXP)
iron(2+) sulfate (anhydrous)  (EXP)
isoprenaline  (EXP)
isoprene  (ISO)
ketamine  (ISO)
lead diacetate  (EXP,ISO)
lead(0)  (EXP,ISO)
lead(2+)  (EXP,ISO)
limonene  (ISO)
lipopolysaccharide  (ISO)
lonafarnib  (ISO)
lovastatin  (ISO)
LY294002  (ISO)
malathion  (ISO)
Manumycin A  (EXP,ISO)
MeIQ  (ISO)
MeIQx  (EXP)
mercury atom  (EXP)
mercury dichloride  (EXP)
mercury(0)  (EXP)
metformin  (ISO)
methamphetamine  (EXP)
methapyrilene  (EXP)
methoxychlor  (EXP)
methyl methanesulfonate  (ISO)
methylglyoxal  (EXP)
Mezerein  (ISO)
mifepristone  (ISO)
monosodium L-glutamate  (EXP)
myricetin  (ISO)
N-acetyl-L-cysteine  (EXP,ISO)
N-ethyl-N-nitrosourea  (ISO)
N-hydroxy-4-aminobiphenyl  (ISO)
N-methyl-N'-nitro-N-nitrosoguanidine  (ISO)
N-methyl-N-nitrosourea  (EXP,ISO)
N-nitrosodiethylamine  (EXP,ISO)
NAD zwitterion  (ISO)
NAD(+)  (ISO)
naringin  (EXP,ISO)
nicotine  (EXP,ISO)
nimesulide  (ISO)
nitrofurazone  (EXP)
obeticholic acid  (ISO)
ochratoxin A  (EXP)
ozone  (EXP,ISO)
paclitaxel  (ISO)
paracetamol  (ISO)
paraquat  (ISO)
parathion  (ISO)
phenobarbital  (ISO)
PhIP  (EXP,ISO)
phlorizin  (ISO)
phorbol 13-acetate 12-myristate  (ISO)
plutonium atom  (EXP)
progesterone  (ISO)
quercetin  (ISO)
reactive oxygen species  (ISO)
resveratrol  (ISO)
Risedronate sodium  (ISO)
rotenone  (ISO)
selenium atom  (ISO)
serpentine asbestos  (ISO)
silicon dioxide  (ISO)
simvastatin  (ISO)
sirolimus  (ISO)
sodium arsenite  (EXP,ISO)
SU6656  (ISO)
sulfur dioxide  (EXP)
superoxide  (ISO)
testosterone  (ISO)
tetrachloromethane  (EXP)
Tetranitromethane  (EXP)
thapsigargin  (ISO)
theaflavin  (ISO)
tipifarnib  (EXP,ISO)
toluene  (EXP)
triciribine  (ISO)
trimethyltin  (ISO)
Triptolide  (EXP)
troglitazone  (ISO)
tunicamycin  (ISO)
urethane  (ISO)
ursodeoxycholic acid  (EXP)
valproic acid  (ISO)
vincristine  (ISO)
vinyl carbamate  (ISO)
vitamin E  (ISO)
zearalenone  (ISO)
zidovudine  (ISO)
zoledronic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
apoptotic process  (IMP)
cell aging  (ISO)
cellular response to gamma radiation  (ISO)
cellular senescence  (IBA,IEP,ISO)
defense response to protozoan  (ISO)
endocytosis  (ISO)
intrinsic apoptotic signaling pathway  (ISO)
liver development  (IEP)
negative regulation of cell population proliferation  (ISO)
negative regulation of gene expression  (ISO)
negative regulation of GTPase activity  (ISO)
negative regulation of neuron apoptotic process  (ISO)
positive regulation of actin cytoskeleton reorganization  (ISO)
positive regulation of cell migration  (ISO)
positive regulation of cell population proliferation  (ISO)
positive regulation of DNA replication  (IMP)
positive regulation of epithelial cell proliferation  (ISO)
positive regulation of ERK1 and ERK2 cascade  (IMP,ISO)
positive regulation of gene expression  (ISO)
positive regulation of GTPase activity  (ISO)
positive regulation of interferon-gamma production  (ISO)
positive regulation of JNK cascade  (ISO)
positive regulation of MAP kinase activity  (ISO)
positive regulation of MAPK cascade  (ISO)
positive regulation of miRNA metabolic process  (ISO)
positive regulation of phospholipase C activity  (ISO)
positive regulation of protein phosphorylation  (ISO)
positive regulation of protein targeting to membrane  (ISO)
positive regulation of Ras protein signal transduction  (IMP)
positive regulation of ruffle assembly  (ISO)
positive regulation of transcription by RNA polymerase II  (ISO)
positive regulation of wound healing  (ISO)
Ras protein signal transduction  (IBA,IMP,ISO)
regulation of cell cycle  (ISO)
regulation of long-term neuronal synaptic plasticity  (ISO)
regulation of neurotransmitter receptor localization to postsynaptic specialization membrane  (ISO)
response to isolation stress  (IEP)
small GTPase mediated signal transduction  (ISO)
T cell receptor signaling pathway  (ISO)
T-helper 1 type immune response  (ISO)

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
acute myeloid leukemia pathway  (IEA)
adenosine signaling pathway  (ISO)
B cell receptor signaling pathway  (IEA)
chemokine mediated signaling pathway  (IEA)
chronic myeloid leukemia pathway  (IEA)
endocytosis pathway  (IEA)
endometrial cancer pathway  (IEA)
endothelin signaling pathway  (ISO)
ephrin - ephrin receptor bidirectional signaling axis  (ISO)
epidermal growth factor/neuregulin signaling pathway  (IEA,ISO)
erythropoietin signaling pathway  (ISO)
Fc epsilon receptor mediated signaling pathway  (IEA,ISO)
glioma pathway  (IEA)
gonadotropin-releasing hormone signaling pathway  (IEA)
granulocyte-macrophage colony-stimulating factor signaling pathway  (ISO)
hepatitis C pathway  (IEA)
insulin signaling pathway  (IEA,ISO)
insulin-like growth factor signaling pathway  (ISO)
interleukin-2 signaling pathway  (ISO)
long term depression  (IEA)
long term potentiation  (IEA)
melanoma pathway  (IEA)
mitogen activated protein kinase signaling pathway  (IEA)
mTOR signaling pathway  (ISO)
neurotrophic factor signaling pathway  (IEA)
non-small cell lung carcinoma pathway  (IEA)
phosphatidylinositol 3-kinase class I signaling pathway  (ISO)
platelet-derived growth factor signaling pathway  (ISO)
prostate cancer pathway  (IEA)
renal cell carcinoma pathway  (IEA)
syndecan signaling pathway  (ISO)
T cell receptor signaling pathway  (IEA)
the extracellular signal-regulated Raf/Mek/Erk signaling pathway  (ISO)
thyroid cancer pathway  (IEA)
urinary bladder cancer pathway  (IEA)
vascular endothelial growth factor signaling pathway  (IEA)

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
References

References - curated
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38. Pipeline to import KEGG annotations from KEGG into RGD
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40. Pipeline to import SMPDB annotations from SMPDB into RGD
41. RGD automated data pipeline
42. RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
43. RGD automated import pipeline for gene-chemical interactions
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Additional References at PubMed
PMID:3023901   PMID:8142349   PMID:8316835   PMID:9054499   PMID:9178006   PMID:9219684   PMID:9230043   PMID:9679960   PMID:9765203   PMID:10845775   PMID:11022048   PMID:11877426  
PMID:12202034   PMID:12427827   PMID:12446704   PMID:12477932   PMID:12824760   PMID:12878730   PMID:14500341   PMID:14712229   PMID:15037605   PMID:15572682   PMID:15831492   PMID:15837622  
PMID:16153441   PMID:16213212   PMID:16478791   PMID:16568090   PMID:16717102   PMID:16895916   PMID:16954213   PMID:17260967   PMID:17380122   PMID:17724343   PMID:18218323   PMID:18367547  
PMID:18408766   PMID:18454179   PMID:18556515   PMID:18604197   PMID:19966300   PMID:20154697   PMID:20603646   PMID:21357543   PMID:21444916   PMID:21968647   PMID:22065586   PMID:22829592  
PMID:23027131   PMID:23648844   PMID:24553818   PMID:25533468   PMID:25774517   PMID:26035971   PMID:26568031   PMID:27125250   PMID:28193718  


Genomics

Candidate Gene Status
Hras is a candidate Gene for QTL Hcar4
Comparative Map Data
Hras
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21196,290,127 - 196,299,823 (-)NCBImRatBN7.2
mRatBN7.2 Ensembl1196,296,263 - 196,300,615 (-)Ensembl
Rnor_6.01214,178,404 - 214,181,841 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1214,178,407 - 214,181,686 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01221,095,943 - 221,099,362 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41201,385,705 - 201,388,987 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11201,540,000 - 201,542,640 (-)NCBI
Celera1193,930,281 - 193,933,583 (-)NCBICelera
RH 3.4 Map11437.21RGD
Cytogenetic Map1q41NCBI
HRAS
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl11532,242 - 537,321 (-)EnsemblGRCh38hg38GRCh38
GRCh3811532,242 - 535,576 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh3711532,242 - 535,576 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 3611522,242 - 525,550 (-)NCBINCBI36hg18NCBI36
Build 3411522,242 - 525,550NCBI
Celera11594,708 - 598,010 (-)NCBI
Cytogenetic Map11p15.5NCBI
HuRef11346,981 - 349,115 (-)NCBIHuRef
CHM1_111529,852 - 534,465 (-)NCBICHM1_1
Hras
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm397140,769,847 - 140,773,938 (-)NCBIGRCm39mm39
GRCm39 Ensembl7140,769,018 - 140,773,918 (-)Ensembl
GRCm387141,189,934 - 141,194,019 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl7141,189,105 - 141,194,005 (-)EnsemblGRCm38mm10GRCm38
MGSCv377148,375,833 - 148,379,903 (-)NCBIGRCm37mm9NCBIm37
MGSCv367141,042,668 - 141,044,260 (-)NCBImm8
Celera7140,983,643 - 140,987,701 (-)NCBICelera
Cytogenetic Map7F5NCBI
cM Map786.48NCBI
Hras
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495547611,508,126 - 11,510,333 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495547611,508,446 - 11,510,333 (+)NCBIChiLan1.0ChiLan1.0
HRAS
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.111568,305 - 571,078 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl11568,305 - 571,078 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v011537,488 - 540,810 (-)NCBIMhudiblu_PPA_v0panPan3
HRAS
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11825,642,844 - 25,644,717 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1825,642,844 - 25,644,717 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1825,291,831 - 25,293,704 (-)NCBI
ROS_Cfam_1.01826,227,144 - 26,230,043 (-)NCBI
UMICH_Zoey_3.11825,736,932 - 25,738,805 (-)NCBI
UNSW_CanFamBas_1.01825,381,917 - 25,383,790 (-)NCBI
UU_Cfam_GSD_1.01825,994,065 - 25,995,938 (-)NCBI
Hras
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404947375,371 - 378,065 (-)NCBI
SpeTri2.0NW_004936888375,372 - 378,125 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
HRAS
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl2299,660 - 302,501 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.12299,662 - 302,539 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
HRAS
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11343,613 - 345,782 (-)NCBI
ChlSab1.1 Ensembl1343,506 - 346,637 (-)Ensembl
Vero_WHO_p1.0NW_02366603897,407,188 - 97,410,502 (-)NCBI
Hras
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462476621,907,423 - 21,913,414 (+)NCBI

Position Markers
RH94696  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21196,301,010 - 196,301,262 (+)MAPPERmRatBN7.2
Rnor_6.01214,183,026 - 214,183,277NCBIRnor6.0
Rnor_5.01221,100,565 - 221,100,816UniSTSRnor5.0
RGSC_v3.41201,390,327 - 201,390,578UniSTSRGSC3.4
Celera1193,934,893 - 193,935,144UniSTS
RH 3.4 Map11437.21UniSTS
Cytogenetic Map1q41UniSTS
PMC112649P2  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21196,298,157 - 196,298,354 (+)MAPPERmRatBN7.2
Rnor_6.01214,180,173 - 214,180,369NCBIRnor6.0
Rnor_5.01221,097,712 - 221,097,908UniSTSRnor5.0
RGSC_v3.41201,387,474 - 201,387,670UniSTSRGSC3.4
Celera1193,932,050 - 193,932,246UniSTS
Cytogenetic Map1q41UniSTS
PMC86690P1  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21196,298,701 - 196,299,122 (+)MAPPERmRatBN7.2
Rnor_6.01214,180,717 - 214,181,137NCBIRnor6.0
Rnor_5.01221,098,256 - 221,098,676UniSTSRnor5.0
RGSC_v3.41201,388,018 - 201,388,438UniSTSRGSC3.4
Celera1193,932,594 - 193,933,014UniSTS
Cytogenetic Map1q41UniSTS


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
70209Niddm23Non-insulin dependent diabetes mellitus QTL 232.82blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)194494440198324465Rat
619613Bp77Blood pressure QTL 770.01arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1164747424209747424Rat
619613Bp77Blood pressure QTL 770.01arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)1164747424209747424Rat
619614Bp78Blood pressure QTL 780.001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1169112897197261052Rat
619614Bp78Blood pressure QTL 780.001arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)1169112897197261052Rat
631205Bp196Blood pressure QTL 19640.0001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1118944897199050459Rat
631214Bw61Body weight QTL613.40.0001intramuscular adipose amount (VT:0010044)intramuscular fat area (CMO:0001162)1173108781218108781Rat
2302378Insul11Insulin level QTL 113.25blood insulin amount (VT:0001560)serum insulin level (CMO:0000358)1144267353251128347Rat
631260Tcas2Tongue tumor susceptibility QTL 24.93tongue integrity trait (VT:0010553)number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)1192485903199050587Rat
70160Bw18Body weight QTL 185.7body mass (VT:0001259)body weight (CMO:0000012)1144267353196383635Rat
70163Bw20Body weight QTL 205.1body mass (VT:0001259)body weight (CMO:0000012)1174133260219133260Rat
724531Uae5Urinary albumin excretion QTL 54urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)1150700142252085212Rat
724559Pancm1Pancreatic morphology QTL 17.1islet of Langerhans morphology trait (VT:0005215)pancreatic islet damage composite score (CMO:0001156)1181759564214537555Rat
724562Rends1Renal damage susceptibility QTL 10.05kidney glomerulus integrity trait (VT:0010546)index of glomerular damage (CMO:0001135)1169537671214537671Rat
1331749Hrtrt11Heart rate QTL 112.973heart pumping trait (VT:2000009)heart rate (CMO:0000002)194494440198211706Rat
737828Hcas3Hepatocarcinoma susceptibility QTL 34.9liver integrity trait (VT:0010547)liver tumorous lesion volume to total liver volume ratio (CMO:0001082)1144267353222987745Rat
631658Cm7Cardiac mass QTL 75.320.0001aorta mass (VT:0002845)aorta weight (CMO:0000076)1196248093241248093Rat
631670Iddm10Insulin dependent diabetes mellitus QTL 101.9blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)1174133260196383635Rat
737977Bp160Blood pressure QTL 1600.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1181133855226133855Rat
1354580Scort1Serum corticosterone level QTL 13.4blood corticosterone amount (VT:0005345)blood corticosterone level (CMO:0001172)1156677124256448636Rat
1582206Kidm33Kidney mass QTL 336.9kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)1188377360224054420Rat
731168Bp154Blood pressure QTL 1543.4arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)194642722214537671Rat
738032Hcas5Hepatocarcinoma susceptibility QTL 53.12liver integrity trait (VT:0010547)liver tumorous lesion number (CMO:0001068)1176426412257976495Rat
631549Bp89Blood pressure QTL 895.7arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1123350581201284552Rat
1302787Stl25Serum triglyceride level QTL 252.70.0073blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)1180359209210702199Rat
1598853Memor3Memory QTL 34.5exploratory behavior trait (VT:0010471)total horizontal distance resulting from voluntary locomotion in an experimental apparatus (CMO:0001443)1143506580212458660Rat
2300161Bmd43Bone mineral density QTL 438.40.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)1171629477216629477Rat
2300174Bmd42Bone mineral density QTL 428.40.0001lumbar vertebra mineral mass (VT:0010511)bone mineral density (CMO:0001226)1171629477216629477Rat
2300187Bmd41Bone mineral density QTL 418.90.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)1171629477216629477Rat
2293654Bss30Bone structure and strength QTL 3032.650.0001femur strength trait (VT:0010010)femur midshaft polar moment of inertia (CMO:0001669)1171629477216629477Rat
2293673Bss27Bone structure and strength QTL 2718.630.0001femur morphology trait (VT:0000559)femur midshaft cortical cross-sectional area (CMO:0001663)1171629477216629477Rat
2293677Bss41Bone structure and strength QTL 419.380.0001lumbar vertebra size trait (VT:0010518)lumbar vertebra cross-sectional area (CMO:0001689)1171629477216629477Rat
2293689Bss47Bone structure and strength QTL 477.250.0001lumbar vertebra size trait (VT:0010518)lumbar vertebra trabecular cross-sectional area (CMO:0001692)1171629477216629477Rat
2293693Bss22Bone structure and strength QTL 2233.520.0001femur morphology trait (VT:0000559)femur cross-sectional area (CMO:0001661)1171629477216629477Rat
631838Niddm36Non-insulin dependent diabetes mellitus QTL 360.01insulin secretion trait (VT:0003564)calculated pancreatic islet insulin release measurement (CMO:0001217)1184550676229550676Rat
634312Bp143Blood pressure QTL 14330.0002arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1182623426219932796Rat
634314Niddm44Non-insulin dependent diabetes mellitus QTL 44blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)149393289199050459Rat
634321Hc1Hypercalciuria QTL 12.91urine calcium amount (VT:0002985)urine calcium excretion rate (CMO:0000763)1178810256240830002Rat
634338Hcar4Hepatocarcinoma resistance QTL 44.6liver integrity trait (VT:0010547)liver tumorous lesion number to liver area ratio (CMO:0001210)1193422268214537671Rat
1600380Niddm70Non-insulin dependent diabetes mellitus QTL 703.10.0008blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)1176550523221550523Rat
1600388Niddm67Non-insulin dependent diabetes mellitus QTL 675.840.000004blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)1195804352257091168Rat
1600395Niddm69Non-insulin dependent diabetes mellitus QTL 694.140.0002blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)1195804352257091168Rat
1600396Niddm68Non-insulin dependent diabetes mellitus QTL 684.970.0003blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)1195804352257091168Rat
1578759Uae30Urinary albumin excretion QTL 303.30.003urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)1150700247252085048Rat
1578763Kidm29Kidney mass QTL 293.30.0001kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)1179567751260522016Rat
1578778Pur4Proteinuria QTL 43.30.003total urine protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)1150700247252085048Rat
1578780Cm52Cardiac mass QTL 523.30.0001heart mass (VT:0007028)heart wet weight (CMO:0000069)181591954219808434Rat
1300145Rf7Renal function QTL 72.96urine creatinine amount (VT:0010540)urine creatinine level (CMO:0000125)1185145134221264292Rat
1354591Cm36Cardiac mass QTL 364.1heart left ventricle mass (VT:0007031)calculated heart weight (CMO:0000073)1102813953201278233Rat
1354602Bw35Body weight QTL 3512.2body mass (VT:0001259)body weight (CMO:0000012)1151162512201278233Rat
1354606Bp246Blood pressure QTL 2463.6arterial blood pressure trait (VT:2000000)pulse pressure (CMO:0000292)1102813953218753816Rat
1354610Bw34Body weight QTL 344.1body mass (VT:0001259)body weight (CMO:0000012)1151162512256448636Rat
1354615Cm32Cardiac mass QTL 325.2heart left ventricle mass (VT:0007031)heart left ventricle wet weight (CMO:0000071)1102813953201278233Rat
1354618Kidm15Kidney mass QTL 155kidney mass (VT:0002707)left kidney wet weight (CMO:0000083)1156677124201278233Rat
1354620Kidm19Kidney mass QTL 194kidney mass (VT:0002707)calculated kidney weight (CMO:0000160)1151162512201278233Rat
1354624Cm35Cardiac mass QTL355.7heart left ventricle mass (VT:0007031)calculated heart weight (CMO:0000073)1177227632256448636Rat
1354634Kidm12Kidney mass QTL 123.9kidney mass (VT:0002707)right kidney wet weight (CMO:0000082)1151162512201278233Rat
1354636Lmblg1Limb length QTL 16.4tibia length (VT:0004357)tibia length (CMO:0000450)1151162512201278233Rat
1354646Kidm18Kidney mass QTL 185.7kidney mass (VT:0002707)calculated kidney weight (CMO:0000160)1151162512256448636Rat
1354652Kidm20Kidney mass QTL 204.3kidney mass (VT:0002707)calculated kidney weight (CMO:0000160)1177227632256448636Rat
1354653Despr9Despair related QTL 90.00019locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)1167909849212909849Rat
1354661Bw33Body weight QTL 335.2body mass (VT:0001259)body weight (CMO:0000012)1151162512256448636Rat
1359018Hrtrt20Heart rate QTL 203.08heart pumping trait (VT:2000009)heart rate (CMO:0000002)1185356336202902618Rat
1558658Bw59Body weight QTL 593.50.0003body mass (VT:0001259)body weight (CMO:0000012)1178784622223784622Rat
1549837Hcar15Hepatocarcinoma resistance QTL 150.05liver integrity trait (VT:0010547)liver tumorous lesion number (CMO:0001068)1153136852260522016Rat
1358191Ept10Estrogen-induced pituitary tumorigenesis QTL 103.8pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)1192825253243914732Rat
2292220Bp306Blood pressure QTL 3063.470.00087arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1164310393243914901Rat
2292222Bp307Blood pressure QTL 3073.060.0014arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1164310393213533942Rat
2293083Iddm25Insulin dependent diabetes mellitus QTL 254.18blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)1181829673224569684Rat
2312420Pur17Proteinuria QTL 177.10.0001urine protein amount (VT:0005160)urine total protein excretion rate (CMO:0000756)1156677124218753816Rat
2312564Glom18Glomerulus QTL 182.40.003kidney glomerulus morphology trait (VT:0005325)index of glomerular damage (CMO:0001135)1185356336231689108Rat
2303622Vencon6Ventilatory control QTL 60.001respiration trait (VT:0001943)respiration rate (CMO:0000289)1154561505199561505Rat
1358886Bp260Blood pressure QTL 2603.67arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1151162766225824951Rat
1358898Bp255Blood pressure QTL 2553.6arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1191019702246062233Rat
1549830Bss1Bone structure and strength QTL 14.8femur strength trait (VT:0010010)femur ultimate force (CMO:0001675)1172609619217609619Rat
1358292Cm37Cardiac mass QTL 376.20.00000081heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)1196248093241248093Rat
1358294Bw37Body weight QTL 3750.000011body mass (VT:0001259)body weight (CMO:0000012)1171310381216310381Rat
61341Bp26Blood pressure QTL 26arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1169537671214537671Rat
61343Bp28Blood pressure QTL 28arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1151646613196646613Rat
61347Bp197Blood pressure QTL 1974.2arterial blood pressure trait (VT:2000000)blood pressure measurement (CMO:0000003)1158633083203633083Rat
61348Bp30Blood pressure QTL 302.4arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1144017057197814409Rat
61378Bp43Blood pressure QTL 4322.6arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1181746937196383635Rat
4889428Stresp24Stress response QTL 240.05heart pumping trait (VT:2000009)absolute change in electrocardiographic low frequency R-R spectral component to high frequency R-R spectral component ratio (CMO:0002162)1155866514200866514Rat
6480780Insul18Insulin level QTL 184.11blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)1189607473200611765Rat
6903303Scl34Serum cholesterol QTL 342.50.0033blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)1180359209218108781Rat
8655655Arrd2Age-related retinal degeneration QTL 27.79retinal layer morphology trait (VT:0003727)percentage of study population developing retinopathy during a period of time (CMO:0002453)1183970203243914901Rat
7794788Mcs32Mammary carcinoma susceptibility QTL 322.61mammary gland integrity trait (VT:0010552)mammary tumor incidence/prevalence measurement (CMO:0000946)1115540693238914717Rat
7771612Cm80Cardiac mass QTL 808.4heart left ventricle mass (VT:0007031)heart left ventricle weight (CMO:0000776)1149448574221264292Rat
7421630Bp362Blood pressure QTL 3620.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1118608292241799120Rat
8552891Epfw5Epididymal fat weight QTL 54.4epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)1193113876238113876Rat
8655855Arrd3Age-related retinal degeneration QTL 33.07lens clarity trait (VT:0001304)cataract incidence/prevalence measurement (CMO:0001585)1183970203243914901Rat
10059590Kidm44Kidney mass QTL 443.420.025kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)1191033875236033875Rat
10059597Bp377Blood pressure QTL 3773.420.025arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)132737458199368955Rat
10059600Bp378Blood pressure QTL 3783.080.05arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1176869060221869060Rat

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:111
Count of miRNA genes:87
Interacting mature miRNAs:97
Transcripts:ENSRNOT00000022363
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 3 43 55 41 19 41 8 11 74 35 39 11 8
Low 2 2
Below cutoff

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001098241 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001130441 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006230535 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017589006 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017589007 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017589008 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039107931 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_005503267 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC118351 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY157970 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC086608 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC099130 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH473953 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CO567790 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JACYVU010000044 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  M13011 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  M15188 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  M61016 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSRNOT00000022363   ⟹   ENSRNOP00000022363
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1196,296,263 - 196,300,615 (-)Ensembl
Rnor_6.0 Ensembl1214,178,407 - 214,181,686 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000079464   ⟹   ENSRNOP00000069770
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1196,296,392 - 196,300,615 (-)Ensembl
Rnor_6.0 Ensembl1214,178,407 - 214,181,686 (-)Ensembl
RefSeq Acc Id: NM_001098241   ⟹   NP_001091711
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21196,296,389 - 196,299,671 (-)NCBI
Rnor_6.01214,178,404 - 214,181,686 (-)NCBI
Rnor_5.01221,095,943 - 221,099,362 (-)NCBI
RGSC_v3.41201,385,705 - 201,388,987 (-)RGD
Celera1193,930,281 - 193,933,583 (-)RGD
Sequence:
RefSeq Acc Id: NM_001130441   ⟹   NP_001123913
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21196,296,389 - 196,299,671 (-)NCBI
Rnor_6.01214,178,404 - 214,181,686 (-)NCBI
Rnor_5.01221,095,943 - 221,099,362 (-)NCBI
RGSC_v3.41201,385,705 - 201,388,987 (-)RGD
Celera1193,930,281 - 193,933,583 (-)RGD
Sequence:
RefSeq Acc Id: XM_006230535   ⟹   XP_006230597
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21196,296,609 - 196,299,823 (-)NCBI
Rnor_6.01214,178,620 - 214,181,841 (-)NCBI
Rnor_5.01221,095,943 - 221,099,362 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017589008   ⟹   XP_017444497
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21196,296,609 - 196,299,703 (-)NCBI
Rnor_6.01214,179,070 - 214,181,699 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039107931   ⟹   XP_038963859
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21196,290,127 - 196,299,823 (-)NCBI
RefSeq Acc Id: XR_005503267
RefSeq Status:
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21196,296,609 - 196,299,703 (-)NCBI
Reference Sequences
RefSeq Acc Id: NP_001123913   ⟸   NM_001130441
- UniProtKB: P20171 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001091711   ⟸   NM_001098241
- UniProtKB: P20171 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_006230597   ⟸   XM_006230535
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_017444497   ⟸   XM_017589008
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: ENSRNOP00000069770   ⟸   ENSRNOT00000079464
RefSeq Acc Id: ENSRNOP00000022363   ⟸   ENSRNOT00000022363
RefSeq Acc Id: XP_038963859   ⟸   XM_039107931
- Peptide Label: isoform X1

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13690533
Promoter ID:EPDNEW_R1057
Type:initiation region
Name:Hras_1
Description:HRas proto-oncogene, GTPase
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01214,181,675 - 214,181,735EPDNEW

Strain Variation

Strain Sequence Variants (Rnor 6.0)
ACI/EurMcwi (2019)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
ACI/EurMcwi (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
ACI/EurMcwi (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
ACI/N (2020)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
ACI/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
BBDP/Wor (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
BN-Lx/CubMcwi (2019)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/NHsdMcwi (2019)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/NHsdMcwi (2020)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/SsN (2020)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/SsN (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
BUF/N (2020)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BXH2/CubMcwi (2020)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BXH3/CubMcwi (2020)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
Buf/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
COP/CrCrl (MCW & UW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
University of Wisconsin (Dr. James Shull)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Charles River Laboratories
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob) and UW Madison (Dr. James Shull)
DA/OlaHsd (2019)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Envigo
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/DuCrl (2019)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/N (2020)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/NCrl (2019)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/NCrl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
F344/NRrrc (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
F344/Stm (2019)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FHH/EurMcwi (2019)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FHH/EurMcwi (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
FHH/EurMcwi (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
FHL/EurMcwi (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
FHL/EurMcwi (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
FXLE16/Stm (2020)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FXLE18/Stm (2020)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
GH/OmrMcwi (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
GK/FarMcwi (2019)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
GK/Ox (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
HXB10/IpcvMcwi (2019)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB2/IpcvMcwi (2019)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB20/IpcvMcwi (2020)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB31/IpcvMcwi (2019)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB4/IpcvMcwi (2020)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LE/Stm (2019)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LE/Stm (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LEW/Crl (2019)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEW/Crl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LEW/NCrlBR (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LEXF10A/StmMcwi (2020)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF11/Stm (2020)
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