(S)-(-)-perillyl alcohol multiple interactions ISO RGD:11215 6480464 perillyl alcohol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of RAF1 protein] CTD PMID:19161993 (S)-nicotine increases activity ISO RGD:737596 6480464 Nicotine results in increased activity of RAF1 protein CTD PMID:17459420 (S)-nicotine affects localization ISO RGD:11215 6480464 Nicotine affects the localization of RAF1 protein CTD PMID:15574422 (S)-nicotine multiple interactions ISO RGD:737596 6480464 Aconitine analog inhibits the reaction [Nicotine promotes the reaction [RB1 protein binds to RAF1 protein]] more ... CTD PMID:16862215 15-deoxy-Delta(12,14)-prostaglandin J2 multiple interactions ISO RGD:11215 6480464 15-deoxy-delta(12, 14)-prostaglandin J2 results in increased activity of and results in decreased phosphorylation of RAF1 protein CTD PMID:12083801 17beta-estradiol increases activity ISO RGD:737596 6480464 Estradiol results in increased activity of RAF1 protein CTD PMID:12432273 17beta-estradiol increases phosphorylation ISO RGD:737596 6480464 Estradiol results in increased phosphorylation of RAF1 protein CTD PMID:15930183 , PMID:27026707 17beta-estradiol decreases expression ISO RGD:737596 6480464 Estradiol results in decreased expression of RAF1 mRNA CTD PMID:16029874 17beta-estradiol 3-benzoate decreases phosphorylation EXP 6480464 estradiol 3-benzoate results in decreased phosphorylation of RAF1 protein CTD PMID:15778002 2,2',4,4',5,5'-hexachlorobiphenyl multiple interactions ISO RGD:737596 6480464 2 more ... CTD PMID:20840854 2,2',4,4'-Tetrabromodiphenyl ether increases expression ISO RGD:737596 6480464 2 more ... CTD PMID:26988655 2,3,7,8-tetrachlorodibenzodioxine affects localization ISO RGD:11215 6480464 Tetrachlorodibenzodioxin affects the localization of RAF1 protein CTD PMID:19555203 2,3,7,8-tetrachlorodibenzodioxine increases expression EXP 6480464 Tetrachlorodibenzodioxin results in increased expression of RAF1 mRNA CTD PMID:18708364 2,3,7,8-tetrachlorodibenzodioxine multiple interactions EXP 6480464 AHR protein promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of RAF1 mRNA] CTD PMID:18708364 2,3,7,8-tetrachlorodibenzodioxine increases expression ISO RGD:11215 6480464 Tetrachlorodibenzodioxin results in increased expression of RAF1 mRNA CTD PMID:19465110 2,3,7,8-tetrachlorodibenzodioxine multiple interactions ISO RGD:11215 6480464 Tetrachlorodibenzodioxin promotes the reaction [Dimethylnitrosamine results in increased expression of RAF1 protein] CTD PMID:11884234 , PMID:19555203 2,4-dinitrotoluene affects expression EXP 6480464 2, 4-dinitrotoluene affects the expression of RAF1 mRNA CTD PMID:21346803 2-deoxy-D-glucose multiple interactions EXP 6480464 RAF1 protein affects the reaction [AICA ribonucleotide results in increased uptake of Deoxyglucose] CTD PMID:11978788 3,3',4,4',5-pentachlorobiphenyl multiple interactions ISO RGD:737596 6480464 3 more ... CTD PMID:20840854 3,3',4,4'-tetrachlorobiphenyl multiple interactions ISO RGD:737596 6480464 3 more ... CTD PMID:18708364 3,3',4,4'-tetrachlorobiphenyl multiple interactions EXP 6480464 3 more ... CTD PMID:18708364 3,3',4,4'-tetrachlorobiphenyl increases expression EXP 6480464 3 more ... CTD PMID:18708364 3,4-methylenedioxymethamphetamine increases expression ISO RGD:11215 6480464 N-Methyl-3, 4-methylenedioxyamphetamine results in increased expression of RAF1 mRNA CTD PMID:20188158 3-\{1-[3-(dimethylamino)propyl]-1H-indol-3-yl\}-4-(1H-indol-3-yl)-1H-pyrrole-2,5-dione multiple interactions ISO RGD:11215 6480464 bisindolylmaleimide I inhibits the reaction [cypermethrin results in increased phosphorylation of RAF1 protein], bisindolylmaleimide I inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of RAF1 protein] CTD PMID:14623285 , PMID:29149324 3-isobutyl-1-methyl-7H-xanthine multiple interactions EXP 6480464 [FSHB protein co-treated with 1-Methyl-3-isobutylxanthine] inhibits the reaction [Testosterone promotes the reaction [RAF1 results in increased phosphorylation of MAP2K1 protein]], [FSHB protein co-treated with 1-Methyl-3-isobutylxanthine] inhibits the reaction [Testosterone results in increased phosphorylation of and results in increased activity of RAF1 protein] CTD PMID:21177760 4,4'-diaminodiphenylmethane affects expression ISO RGD:11215 6480464 4, 4'-diaminodiphenylmethane affects the expression of RAF1 mRNA CTD PMID:18648102 4-(N-nitrosomethylamino)-1-(3-pyridyl)butan-1-one increases activity ISO RGD:737596 6480464 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased activity of RAF1 protein CTD PMID:17459420 4-amino-2,6-dinitrotoluene affects expression EXP 6480464 4-amino-2, 6-dinitrotoluene affects the expression of RAF1 mRNA CTD PMID:21346803 4-hydroxynon-2-enal increases expression ISO RGD:11215 6480464 4-hydroxy-2-nonenal results in increased expression of RAF1 mRNA CTD PMID:19191707 5-fluorouracil increases expression ISO RGD:737596 6480464 Fluorouracil results in increased expression of RAF1 mRNA CTD PMID:15152939 5-fluorouracil decreases expression ISO RGD:11215 6480464 Fluorouracil results in decreased expression of RAF1 protein CTD PMID:21296659 7,12-dimethyltetraphene multiple interactions ISO RGD:11215 6480464 [Tetradecanoylphorbol Acetate co-treated with 9 more ... CTD PMID:22760862 acetylsalicylic acid decreases expression ISO RGD:737596 6480464 Aspirin results in decreased expression of RAF1 mRNA CTD PMID:20457246 aconitine multiple interactions ISO RGD:737596 6480464 Aconitine analog inhibits the reaction [Nicotine promotes the reaction [RB1 protein binds to RAF1 protein]] CTD PMID:16862215 acrylamide increases expression ISO RGD:11215 6480464 Acrylamide results in increased expression of RAF1 mRNA CTD PMID:30807115 actinomycin D decreases expression EXP 6480464 Dactinomycin results in decreased expression of RAF1 protein CTD PMID:15959627 afimoxifene decreases response to substance ISO RGD:737596 6480464 RAF1 results in decreased susceptibility to afimoxifene CTD PMID:21233418 AICA ribonucleotide multiple interactions EXP 6480464 RAF1 protein affects the reaction [AICA ribonucleotide results in increased uptake of Deoxyglucose] CTD PMID:11978788 all-trans-retinoic acid increases phosphorylation ISO RGD:737596 6480464 Tretinoin results in increased phosphorylation of RAF1 protein CTD PMID:19038232 ammonium chloride affects expression EXP 6480464 Ammonium Chloride affects the expression of RAF1 mRNA CTD PMID:16483693 ammonium chloride increases expression EXP 6480464 Ammonium Chloride results in increased expression of RAF1 protein CTD PMID:16483693 andrographolide multiple interactions ISO RGD:737596 6480464 andrographolide inhibits the reaction [VEGFA protein results in increased phosphorylation of RAF1 protein] CTD PMID:24814888 Aroclor 1254 increases expression ISO RGD:737596 6480464 Chlorodiphenyl (54% Chlorine) results in increased expression of RAF1 mRNA, Chlorodiphenyl (54% Chlorine) results in increased expression of RAF1 protein CTD PMID:18708364 Aroclor 1254 multiple interactions EXP 6480464 Chlorodiphenyl (54% Chlorine) promotes the reaction [[AHR protein binds to ARNT protein] which binds to RAF1 promoter] CTD PMID:18708364 Aroclor 1254 increases expression EXP 6480464 Chlorodiphenyl (54% Chlorine) results in increased expression of RAF1 mRNA, Chlorodiphenyl (54% Chlorine) results in increased expression of RAF1 protein CTD PMID:18708364 , PMID:8471063 arsane multiple interactions ISO RGD:11215 6480464 Arsenic inhibits the reaction [[NR3C1 protein binds to RAF1 promoter] which results in increased expression of RAF1 mRNA] more ... CTD PMID:21784148 arsenic atom multiple interactions ISO RGD:11215 6480464 Arsenic inhibits the reaction [[NR3C1 protein binds to RAF1 promoter] which results in increased expression of RAF1 mRNA] more ... CTD PMID:21784148 arsenous acid increases expression ISO RGD:737596 6480464 Arsenic Trioxide results in increased expression of RAF1 mRNA CTD PMID:20458559 arsenous acid multiple interactions ISO RGD:737596 6480464 [Arsenic Trioxide co-treated with PD 173074] results in decreased expression of RAF1 protein more ... CTD PMID:27794399 atrazine decreases expression ISO RGD:737596 6480464 Atrazine results in decreased expression of RAF1 mRNA CTD PMID:22378314 benzo[a]pyrene multiple interactions ISO RGD:737596 6480464 2 more ... CTD PMID:20840854 benzo[a]pyrene diol epoxide I decreases expression ISO RGD:737596 6480464 7 more ... CTD PMID:19150397 benzo[e]pyrene decreases methylation ISO RGD:737596 6480464 benzo(e)pyrene results in decreased methylation of RAF1 intron CTD PMID:30157460 bis(2-chloroethyl) sulfide multiple interactions ISO RGD:11215 6480464 Mustard Gas results in increased phosphorylation of and results in increased activity of RAF1 protein CTD PMID:18200059 bisphenol A increases expression EXP 6480464 bisphenol A results in increased expression of RAF1 mRNA, bisphenol A results in increased expression of RAF1 protein CTD PMID:20219716 more ... bortezomib multiple interactions ISO RGD:737596 6480464 [Bortezomib co-treated with Butyrates] results in decreased expression of RAF1 protein more ... CTD PMID:12893773 , PMID:18445700 bortezomib decreases expression ISO RGD:737596 6480464 Bortezomib results in decreased expression of RAF1 protein CTD PMID:18445700 cadmium atom increases expression ISO RGD:737596 6480464 Cadmium results in increased expression of RAF1 protein CTD PMID:14499349 cadmium atom multiple interactions ISO RGD:737596 6480464 GPER1 mutant form inhibits the reaction [Cadmium results in increased activity of RAF1 protein] CTD PMID:20153348 cadmium atom increases activity ISO RGD:737596 6480464 Cadmium results in increased activity of RAF1 protein CTD PMID:20153348 cadmium dichloride decreases phosphorylation ISO RGD:11215 6480464 Cadmium Chloride results in decreased phosphorylation of RAF1 protein CTD PMID:25744307 cadmium dichloride decreases phosphorylation ISO RGD:737596 6480464 Cadmium Chloride results in decreased phosphorylation of RAF1 protein CTD PMID:25744307 calciol multiple interactions ISO RGD:737596 6480464 RAF1 mutant form inhibits the reaction [Cholecalciferol results in increased expression of CD14 protein], RAF1 mutant form inhibits the reaction [Cholecalciferol results in increased expression of RB1 protein] CTD PMID:18628207 calciol increases response to substance ISO RGD:737596 6480464 RAF1 results in increased susceptibility to Cholecalciferol CTD PMID:18628207 carbon nanotube increases expression ISO RGD:11215 6480464 Nanotubes, Carbon analog results in increased expression of RAF1 mRNA, Nanotubes, Carbon results in increased expression of RAF1 mRNA CTD PMID:25620056 chaetoglobosin A decreases phosphorylation EXP 6480464 chaetoglobosins results in decreased phosphorylation of RAF1 protein CTD PMID:18040759 choline increases expression ISO RGD:11215 6480464 Choline results in increased expression of RAF1 mRNA CTD PMID:27664006 ciglitazone increases activity ISO RGD:11215 6480464 ciglitazone results in increased activity of RAF1 protein CTD PMID:12083801 cis-caffeic acid multiple interactions ISO RGD:11215 6480464 caffeic acid inhibits the reaction [Acetaminophen results in increased phosphorylation of RAF1 protein] CTD PMID:27720869 cis-caffeic acid multiple interactions ISO RGD:737596 6480464 caffeic acid inhibits the reaction [Acetaminophen results in increased phosphorylation of RAF1 protein] CTD PMID:27720869 cisplatin decreases response to substance ISO RGD:737596 6480464 RAF1 results in decreased susceptibility to Cisplatin CTD PMID:21849418 cisplatin decreases expression ISO RGD:11215 6480464 Cisplatin results in decreased expression of RAF1 mRNA CTD PMID:26546572 clofibrate decreases expression ISO RGD:11215 6480464 Clofibrate results in decreased expression of RAF1 mRNA CTD PMID:23811191 cocaine multiple interactions EXP 6480464 [[Cocaine results in increased expression of MIR212 mRNA] which results in increased activity of RAF1 protein] which results in increased expression of CRTC1 protein, [Cocaine results in increased expression of MIR212 mRNA] which results in increased activity of RAF1 protein CTD PMID:20613834 copper atom multiple interactions ISO RGD:737596 6480464 [Thiosemicarbazones binds to Copper] which results in increased expression of RAF1 protein CTD PMID:20931265 copper(0) multiple interactions ISO RGD:737596 6480464 [Thiosemicarbazones binds to Copper] which results in increased expression of RAF1 protein CTD PMID:20931265 crocidolite asbestos decreases phosphorylation ISO RGD:737596 6480464 Asbestos, Crocidolite results in decreased phosphorylation of RAF1 protein CTD PMID:17191120 curcumin increases activity ISO RGD:11215 6480464 Curcumin results in increased activity of RAF1 protein CTD PMID:19501152 curcumin multiple interactions ISO RGD:11215 6480464 piplartine inhibits the reaction [Curcumin results in increased activity of RAF1 protein] CTD PMID:19501152 cypermethrin multiple interactions ISO RGD:11215 6480464 1 more ... CTD PMID:14623285 , PMID:29149324 deoxycholic acid multiple interactions ISO RGD:737596 6480464 Deoxycholic Acid results in increased phosphorylation of and results in increased activity of RAF1 protein, Ursodeoxycholic Acid inhibits the reaction [Deoxycholic Acid results in increased phosphorylation of and results in increased activity of RAF1 protein] CTD PMID:14747693 diarsenic trioxide increases expression ISO RGD:737596 6480464 Arsenic Trioxide results in increased expression of RAF1 mRNA CTD PMID:20458559 diarsenic trioxide multiple interactions ISO RGD:737596 6480464 [Arsenic Trioxide co-treated with PD 173074] results in decreased expression of RAF1 protein more ... CTD PMID:27794399 dibutyl phthalate decreases expression ISO RGD:11215 6480464 Dibutyl Phthalate results in decreased expression of RAF1 mRNA CTD PMID:21266533 dibutylstannane multiple interactions ISO RGD:737596 6480464 di-n-butyltin results in decreased expression of and results in decreased phosphorylation of RAF1 protein CTD PMID:24038145 dieldrin multiple interactions ISO RGD:737596 6480464 Dieldrin results in increased phosphorylation of and results in increased activity of RAF1 protein CTD PMID:15888667 dimethyl sulfoxide multiple interactions ISO RGD:737596 6480464 [cucurbitacin IIa co-treated with Dimethyl Sulfoxide] results in increased expression of RAF1 mRNA CTD PMID:31265865 dimethylarsinic acid multiple interactions ISO RGD:737596 6480464 [sodium arsenite co-treated with monomethylarsonic acid co-treated with Cacodylic Acid] affects the expression of RAF1 mRNA CTD PMID:23192986 doxorubicin increases expression ISO RGD:737596 6480464 Doxorubicin results in increased expression of RAF1 mRNA CTD PMID:29803840 eckol decreases activity ISO RGD:737596 6480464 eckol results in decreased activity of RAF1 protein CTD PMID:21514314 emodin decreases expression ISO RGD:737596 6480464 Emodin results in decreased expression of RAF1 mRNA CTD PMID:16045814 emodin multiple interactions EXP 6480464 Emodin inhibits the reaction [PDGFB protein results in increased phosphorylation of RAF1 protein] CTD PMID:15288473 endosulfan multiple interactions ISO RGD:737596 6480464 Endosulfan results in increased phosphorylation of and results in increased activity of RAF1 protein CTD PMID:15888667 erlotinib hydrochloride decreases phosphorylation ISO RGD:11215 6480464 Erlotinib Hydrochloride results in decreased phosphorylation of RAF1 protein CTD PMID:21195724 ethanol affects splicing ISO RGD:11215 6480464 Ethanol affects the splicing of RAF1 mRNA CTD PMID:30319688 ethylene glycol bis(2-aminoethyl)tetraacetic acid multiple interactions ISO RGD:11215 6480464 Egtazic Acid inhibits the reaction [cypermethrin results in increased phosphorylation of and results in increased activity of RAF1 protein] CTD PMID:29149324 flavonoids increases expression EXP 6480464 Flavonoids results in increased expression of RAF1 mRNA CTD PMID:18035473 flutamide increases expression EXP 6480464 Flutamide results in increased expression of RAF1 mRNA CTD PMID:24136188 folic acid affects expression ISO RGD:737596 6480464 Folic Acid affects the expression of RAF1 mRNA CTD PMID:16361273 gamma-hexachlorocyclohexane multiple interactions ISO RGD:737596 6480464 Hexachlorocyclohexane results in increased phosphorylation of and results in increased activity of RAF1 protein CTD PMID:15888667 geldanamycin increases expression ISO RGD:11215 6480464 geldanamycin results in increased expression of RAF1 protein CTD PMID:8816498 geldanamycin decreases expression ISO RGD:737596 6480464 geldanamycin results in decreased expression of RAF1 protein CTD PMID:24450340 geldanamycin multiple interactions ISO RGD:737596 6480464 geldanamycin results in decreased expression of and results in decreased phosphorylation of RAF1 protein CTD PMID:19167484 genistein decreases phosphorylation EXP 6480464 Genistein results in decreased phosphorylation of RAF1 protein CTD PMID:15781664 genistein increases phosphorylation ISO RGD:737596 6480464 Genistein results in increased phosphorylation of RAF1 protein CTD PMID:19038232 gentamycin increases expression EXP 6480464 Gentamicins results in increased expression of RAF1 mRNA CTD PMID:22061828 geraniol multiple interactions ISO RGD:11215 6480464 geraniol inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with 9 more ... CTD PMID:22760862 Goe 6976 multiple interactions EXP 6480464 Go 6976 inhibits the reaction [zinc chloride results in increased phosphorylation of RAF1 protein] CTD PMID:21575692 GW 1929 increases activity ISO RGD:11215 6480464 GW 1929 results in increased activity of RAF1 protein CTD PMID:12083801 heptachlor multiple interactions ISO RGD:737596 6480464 Heptachlor results in increased phosphorylation of and results in increased activity of RAF1 protein CTD PMID:15888667 hydrogen peroxide multiple interactions ISO RGD:11215 6480464 [Hydrogen Peroxide co-treated with Tetradecanoylphorbol Acetate] results in increased activity of RAF1 protein more ... CTD PMID:14623285 , PMID:14975446 hydrogen peroxide increases activity ISO RGD:11215 6480464 Hydrogen Peroxide results in increased activity of RAF1 protein CTD PMID:14623285 hydroxyflutamide multiple interactions ISO RGD:737596 6480464 wortmannin promotes the reaction [hydroxyflutamide results in increased phosphorylation of RAF1 protein] CTD PMID:28163245 hydroxyflutamide increases phosphorylation ISO RGD:737596 6480464 hydroxyflutamide results in increased phosphorylation of RAF1 protein CTD PMID:28163245 indole-3-methanol multiple interactions EXP 6480464 [indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in increased expression of RAF1 mRNA, [indole-3-carbinol co-treated with Diethylnitrosamine] results in increased expression of RAF1 mRNA CTD PMID:22129741 lead diacetate increases phosphorylation ISO RGD:737596 6480464 lead acetate results in increased phosphorylation of RAF1 protein CTD PMID:19133285 lead diacetate multiple interactions ISO RGD:737596 6480464 4-((3-bromophenyl)amino)-6 more ... CTD PMID:19133285 letrozole increases expression ISO RGD:11215 6480464 letrozole results in increased expression of RAF1 protein CTD PMID:15967659 lipopolysaccharide increases activity EXP 6480464 Lipopolysaccharides results in increased activity of RAF1 protein CTD PMID:19039081 lipopolysaccharide multiple interactions EXP 6480464 [Lipopolysaccharides results in increased activity of RAF1 protein] which results in decreased secretion of Nitric Oxide, Methylmercury Compounds inhibits the reaction [Lipopolysaccharides results in increased activity of RAF1 protein] CTD PMID:19039081 lipoteichoic acid increases phosphorylation ISO RGD:11215 6480464 lipoteichoic acid results in increased phosphorylation of RAF1 protein CTD PMID:19573522 lipoteichoic acid multiple interactions ISO RGD:11215 6480464 Propofol inhibits the reaction [lipoteichoic acid results in increased phosphorylation of RAF1 protein], TLR2 protein affects the reaction [lipoteichoic acid results in increased phosphorylation of RAF1 protein] CTD PMID:19573522 lovastatin multiple interactions ISO RGD:737596 6480464 Lovastatin inhibits the reaction [EGF protein results in increased phosphorylation of RAF1 protein] CTD PMID:19760159 lovastatin decreases activity ISO RGD:737596 6480464 Lovastatin results in decreased activity of RAF1 protein CTD PMID:19360310 LY294002 multiple interactions ISO RGD:737596 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Dronabinol results in increased localization of RAF1 protein] more ... CTD PMID:12834810 more ... maneb multiple interactions ISO RGD:11215 6480464 [Maneb co-treated with Paraquat] results in decreased expression of RAF1 mRNA more ... CTD PMID:23963992 mangiferin decreases expression ISO RGD:11215 6480464 mangiferin results in decreased expression of RAF1 mRNA CTD PMID:15135318 Manumycin A multiple interactions EXP 6480464 manumycin inhibits the reaction [Streptozocin results in increased expression of RAF1 protein], manumycin inhibits the reaction [zinc chloride results in increased phosphorylation of RAF1 protein] CTD PMID:18569938 , PMID:21575692 melatonin multiple interactions ISO RGD:11215 6480464 Melatonin inhibits the reaction [[Maneb co-treated with Paraquat] results in decreased expression of RAF1 mRNA] CTD PMID:23963992 metformin decreases phosphorylation ISO RGD:737596 6480464 Metformin results in decreased phosphorylation of RAF1 protein CTD PMID:23707609 methapyrilene decreases methylation ISO RGD:737596 6480464 Methapyrilene results in decreased methylation of RAF1 intron CTD PMID:30157460 methylarsonic acid multiple interactions ISO RGD:737596 6480464 [sodium arsenite co-treated with monomethylarsonic acid co-treated with Cacodylic Acid] affects the expression of RAF1 mRNA CTD PMID:23192986 methylmercury chloride increases phosphorylation EXP 6480464 methylmercuric chloride results in increased phosphorylation of RAF1 protein CTD PMID:29258870 morphine multiple interactions ISO RGD:11215 6480464 HINT1 affects the reaction [Morphine promotes the reaction [OPRM1 protein binds to RAF1 protein]], Morphine promotes the reaction [OPRM1 protein binds to RAF1 protein] CTD PMID:21235400 morphine affects response to substance EXP 6480464 RAF1 protein affects the susceptibility to Morphine CTD PMID:18976650 N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine multiple interactions ISO RGD:11215 6480464 N more ... CTD PMID:21235400 N-acetyl-L-cysteine multiple interactions ISO RGD:11215 6480464 Acetylcysteine inhibits the reaction [NSC 680410 results in decreased expression of RAF1 protein] CTD PMID:16481037 N-acetyl-L-cysteine multiple interactions EXP 6480464 [indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in increased expression of RAF1 mRNA CTD PMID:22129741 N-acetylsphingosine increases activity EXP 6480464 N-acetylsphingosine results in increased activity of RAF1 protein CTD PMID:10700234 N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal multiple interactions ISO RGD:737596 6480464 benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [[arsenic trioxide co-treated with PD 173074] results in decreased expression of RAF1 protein modified form], benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [[arsenic trioxide co-treated with PD 173074] results in decreased expression of RAF1 protein] CTD PMID:27794399 N-methyl-4-phenylpyridinium multiple interactions ISO RGD:737596 6480464 U 0126 affects the reaction [1-Methyl-4-phenylpyridinium affects the expression of RAF1 mRNA] CTD PMID:12710931 N-methyl-4-phenylpyridinium increases cleavage ISO RGD:737596 6480464 1-Methyl-4-phenylpyridinium results in increased cleavage of RAF1 protein CTD PMID:10737593 N-nitrosodiethylamine multiple interactions ISO RGD:11215 6480464 [troglitazone co-treated with Diethylnitrosamine] results in decreased expression of RAF1 mRNA CTD PMID:18597072 N-nitrosodiethylamine increases expression EXP 6480464 Diethylnitrosamine results in increased expression of RAF1 mRNA CTD PMID:2559087 N-nitrosodiethylamine multiple interactions EXP 6480464 [Diethylnitrosamine co-treated with Phenobarbital] results in increased expression of RAF1 protein more ... CTD PMID:22129741 , PMID:7526561 N-nitrosodimethylamine increases expression ISO RGD:11215 6480464 Dimethylnitrosamine results in increased expression of RAF1 protein CTD PMID:11884234 , PMID:19555203 N-nitrosodimethylamine multiple interactions ISO RGD:11215 6480464 Tetrachlorodibenzodioxin promotes the reaction [Dimethylnitrosamine results in increased expression of RAF1 protein] CTD PMID:11884234 , PMID:19555203 naphthalene increases expression ISO RGD:737596 6480464 naphthalene results in increased expression of RAF1 protein CTD PMID:14595851 naringin increases activity EXP 6480464 naringin results in increased activity of RAF1 protein CTD PMID:18951945 naringin multiple interactions EXP 6480464 RAF1 protein affects the reaction [naringin results in decreased expression of CDK2 protein] more ... CTD PMID:18951945 naringin increases phosphorylation ISO RGD:737596 6480464 naringin results in increased phosphorylation of RAF1 protein CTD PMID:18296682 naringin multiple interactions ISO RGD:737596 6480464 RAF1 protein affects the reaction [naringin results in increased expression of CDKN1A protein] more ... CTD PMID:18296682 Niclosamide decreases phosphorylation ISO RGD:737596 6480464 Niclosamide analog results in decreased phosphorylation of RAF1 protein CTD PMID:28284560 Niclosamide decreases expression ISO RGD:737596 6480464 Niclosamide analog results in decreased expression of RAF1 protein, Niclosamide results in decreased expression of RAF1 protein CTD PMID:28284560 nicotine multiple interactions ISO RGD:737596 6480464 Aconitine analog inhibits the reaction [Nicotine promotes the reaction [RB1 protein binds to RAF1 protein]] more ... CTD PMID:16862215 nicotine affects localization ISO RGD:11215 6480464 Nicotine affects the localization of RAF1 protein CTD PMID:15574422 nicotine increases activity ISO RGD:737596 6480464 Nicotine results in increased activity of RAF1 protein CTD PMID:17459420 nimodipine multiple interactions ISO RGD:11215 6480464 Nimodipine inhibits the reaction [cypermethrin results in increased phosphorylation of and results in increased activity of RAF1 protein] CTD PMID:29149324 nitric oxide multiple interactions EXP 6480464 [Lipopolysaccharides results in increased activity of RAF1 protein] which results in decreased secretion of Nitric Oxide CTD PMID:19039081 okadaic acid multiple interactions ISO RGD:11215 6480464 Okadaic Acid inhibits the reaction [[Hydrogen Peroxide co-treated with Tetradecanoylphorbol Acetate] results in increased activity of RAF1 protein] CTD PMID:14623285 ouabain decreases expression ISO RGD:737596 6480464 Ouabain results in decreased expression of RAF1 mRNA CTD PMID:28795476 p-menthan-3-ol decreases expression ISO RGD:737596 6480464 Menthol results in decreased expression of RAF1 mRNA CTD PMID:26760959 paclitaxel increases phosphorylation ISO RGD:737596 6480464 Paclitaxel results in increased phosphorylation of RAF1 protein CTD PMID:12510025 paclitaxel multiple interactions ISO RGD:737596 6480464 [pifithrin co-treated with Paclitaxel] results in increased phosphorylation of RAF1 protein, resveratrol inhibits the reaction [Paclitaxel results in increased phosphorylation of RAF1 protein] CTD PMID:12510025 , PMID:18516295 panobinostat multiple interactions ISO RGD:737596 6480464 [Bortezomib co-treated with panobinostat] results in decreased expression of RAF1 protein CTD PMID:18445700 paracetamol affects expression ISO RGD:11215 6480464 Acetaminophen affects the expression of RAF1 mRNA CTD PMID:17562736 paracetamol multiple interactions ISO RGD:11215 6480464 caffeic acid inhibits the reaction [Acetaminophen results in increased phosphorylation of RAF1 protein] CTD PMID:27720869 paracetamol increases phosphorylation ISO RGD:11215 6480464 Acetaminophen results in increased phosphorylation of RAF1 protein CTD PMID:27720869 paracetamol multiple interactions ISO RGD:737596 6480464 caffeic acid inhibits the reaction [Acetaminophen results in increased phosphorylation of RAF1 protein] CTD PMID:27720869 paracetamol increases phosphorylation ISO RGD:737596 6480464 Acetaminophen results in increased phosphorylation of RAF1 protein CTD PMID:27720869 paracetamol decreases expression ISO RGD:737596 6480464 Acetaminophen results in decreased expression of RAF1 mRNA CTD PMID:25704631 paraquat multiple interactions ISO RGD:11215 6480464 [Maneb co-treated with Paraquat] results in decreased expression of RAF1 mRNA more ... CTD PMID:23963992 Parthenin decreases phosphorylation ISO RGD:737596 6480464 parthenin analog results in decreased phosphorylation of RAF1 protein CTD PMID:25196075 PD173074 decreases expression ISO RGD:737596 6480464 PD 173074 results in decreased expression of RAF1 protein, PD 173074 results in decreased expression of RAF1 protein modified form CTD PMID:27794399 PD173074 multiple interactions ISO RGD:737596 6480464 [arsenic trioxide co-treated with PD 173074] results in decreased expression of RAF1 protein more ... CTD PMID:27794399 perillyl alcohol multiple interactions ISO RGD:11215 6480464 perillyl alcohol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of RAF1 protein] CTD PMID:19161993 phenethyl isothiocyanate decreases expression ISO RGD:737596 6480464 phenethyl isothiocyanate results in decreased expression of RAF1 protein CTD PMID:26456889 phenobarbital multiple interactions EXP 6480464 [Diethylnitrosamine co-treated with Phenobarbital] results in increased expression of RAF1 protein CTD PMID:7526561 phenobarbital decreases expression EXP 6480464 Phenobarbital results in decreased expression of RAF1 mRNA CTD PMID:17381134 phenylephrine multiple interactions EXP 6480464 Docosahexaenoic Acids inhibits the reaction [Phenylephrine results in increased phosphorylation of RAF1 protein] CTD PMID:15258898 phenylephrine increases phosphorylation EXP 6480464 Phenylephrine results in increased phosphorylation of RAF1 protein CTD PMID:15258898 PhIP increases phosphorylation ISO RGD:737596 6480464 2-amino-1-methyl-6-phenylimidazo(4, 5-b)pyridine results in increased phosphorylation of RAF1 protein CTD PMID:22307971 phlorizin decreases expression ISO RGD:11215 6480464 Phlorhizin results in decreased expression of RAF1 mRNA CTD PMID:22538082 phorbol 13-acetate 12-myristate multiple interactions ISO RGD:11215 6480464 [Hydrogen Peroxide co-treated with Tetradecanoylphorbol Acetate] results in increased activity of RAF1 protein more ... CTD PMID:14623285 more ... phorbol 13-acetate 12-myristate increases expression ISO RGD:11215 6480464 Tetradecanoylphorbol Acetate results in increased expression of RAF1 protein CTD PMID:19161993 phorbol 13-acetate 12-myristate increases activity ISO RGD:11215 6480464 Tetradecanoylphorbol Acetate results in increased activity of RAF1 protein CTD PMID:14623285 Piplartine multiple interactions ISO RGD:11215 6480464 piplartine inhibits the reaction [Curcumin results in increased activity of RAF1 protein] CTD PMID:19501152 Piplartine decreases activity ISO RGD:11215 6480464 piplartine results in decreased activity of RAF1 protein CTD PMID:19501152 pirinixic acid decreases expression ISO RGD:11215 6480464 pirinixic acid results in decreased expression of RAF1 mRNA CTD PMID:23811191 potassium dichromate increases expression ISO RGD:737596 6480464 Potassium Dichromate results in increased expression of RAF1 mRNA CTD PMID:11678601 pregnenolone 16alpha-carbonitrile increases expression EXP 6480464 Pregnenolone Carbonitrile results in increased expression of RAF1 mRNA CTD PMID:19162173 progesterone decreases phosphorylation ISO RGD:737596 6480464 Progesterone results in decreased phosphorylation of RAF1 protein CTD PMID:17492661 propofol multiple interactions ISO RGD:11215 6480464 Propofol inhibits the reaction [lipoteichoic acid results in increased phosphorylation of RAF1 protein] CTD PMID:19573522 prostaglandin F2alpha increases expression ISO RGD:11215 6480464 Dinoprost results in increased expression of RAF1 protein modified form CTD PMID:24333336 prostaglandin F2alpha multiple interactions ISO RGD:11215 6480464 resveratrol inhibits the reaction [Dinoprost results in increased expression of RAF1 protein modified form], SRT1720 inhibits the reaction [Dinoprost results in increased expression of RAF1 protein modified form] CTD PMID:24333336 pyrogallol increases expression ISO RGD:11215 6480464 Pyrogallol results in increased expression of RAF1 mRNA CTD PMID:20362636 quercetin multiple interactions ISO RGD:737596 6480464 Quercetin inhibits the reaction [EGF protein results in increased phosphorylation of RAF1 protein], Quercetin inhibits the reaction [TGFA protein results in increased phosphorylation of RAF1 protein] CTD PMID:12888923 quercetin decreases expression ISO RGD:737596 6480464 Quercetin results in decreased expression of RAF1 protein, Quercetin results in decreased expression of RAF1 protein modified form CTD PMID:12653748 , PMID:21308698 quercetin multiple interactions ISO RGD:11215 6480464 Quercetin binds to and results in decreased activity of RAF1 protein CTD PMID:18245498 quercetin decreases phosphorylation ISO RGD:737596 6480464 Quercetin results in decreased phosphorylation of RAF1 protein CTD PMID:12888923 quinomethionate affects expression ISO RGD:737596 6480464 quinomethionate affects the expression of RAF1 mRNA CTD PMID:15387888 resveratrol multiple interactions ISO RGD:737596 6480464 resveratrol inhibits the reaction [3 more ... CTD PMID:12510025 , PMID:18708364 resveratrol multiple interactions ISO RGD:11215 6480464 resveratrol inhibits the reaction [Dinoprost results in increased expression of RAF1 protein modified form] CTD PMID:24333336 resveratrol decreases expression ISO RGD:737596 6480464 resveratrol results in decreased expression of RAF1 protein CTD PMID:18089832 resveratrol multiple interactions EXP 6480464 resveratrol inhibits the reaction [3 more ... CTD PMID:18708364 romidepsin decreases expression ISO RGD:737596 6480464 romidepsin results in decreased expression of RAF1 protein CTD PMID:15014036 rottlerin decreases phosphorylation ISO RGD:737596 6480464 rottlerin results in decreased phosphorylation of RAF1 protein CTD PMID:15949478 S-nitroso-N-acetyl-D-penicillamine multiple interactions ISO RGD:11215 6480464 S-Nitroso-N-Acetylpenicillamine promotes the reaction [OPRM1 protein binds to RAF1 protein] CTD PMID:21235400 Salvianolic acid A decreases phosphorylation ISO RGD:737596 6480464 salvianolic acid A results in decreased phosphorylation of RAF1 protein CTD PMID:29385302 sevoflurane affects expression EXP 6480464 sevoflurane affects the expression of RAF1 mRNA CTD PMID:15967596 simvastatin decreases activity ISO RGD:737596 6480464 Simvastatin results in decreased activity of RAF1 protein CTD PMID:19360310 simvastatin multiple interactions EXP 6480464 Simvastatin inhibits the reaction [Streptozocin results in increased expression of RAF1 protein] CTD PMID:18569938 sirolimus multiple interactions ISO RGD:737596 6480464 [7-hydroxystaurosporine co-treated with Sirolimus] results in decreased expression of RAF1 protein CTD PMID:15767555 sodium arsenite multiple interactions ISO RGD:737596 6480464 [sodium arsenite co-treated with monomethylarsonic acid co-treated with Cacodylic Acid] affects the expression of RAF1 mRNA CTD PMID:23192986 sodium arsenite decreases expression ISO RGD:11215 6480464 sodium arsenite results in decreased expression of RAF1 mRNA CTD PMID:19822182 sodium arsenite increases activity ISO RGD:737596 6480464 sodium arsenite results in increased activity of RAF1 protein CTD PMID:9442025 sodium dichromate decreases expression ISO RGD:11215 6480464 sodium bichromate results in decreased expression of RAF1 mRNA CTD PMID:22155349 sodium dichromate increases expression ISO RGD:11215 6480464 sodium bichromate results in increased expression of RAF1 mRNA CTD PMID:22155349 sorafenib decreases activity ISO RGD:737596 6480464 sorafenib results in decreased activity of RAF1 protein CTD PMID:19139124 , PMID:21531053 streptozocin multiple interactions EXP 6480464 manumycin inhibits the reaction [Streptozocin results in increased expression of RAF1 protein] more ... CTD PMID:18569938 , PMID:23562514 streptozocin decreases expression EXP 6480464 Streptozocin results in decreased expression of RAF1 protein CTD PMID:23562514 streptozocin increases expression EXP 6480464 Streptozocin results in increased expression of RAF1 protein CTD PMID:18569938 styrene increases expression ISO RGD:737596 6480464 Styrene results in increased expression of RAF1 protein CTD PMID:15212811 SU6656 multiple interactions ISO RGD:737596 6480464 SU 6656 inhibits the reaction [lead acetate results in increased phosphorylation of RAF1 protein] CTD PMID:19133285 tanespimycin decreases expression ISO RGD:737596 6480464 tanespimycin results in decreased expression of RAF1 protein CTD PMID:10564678 Tautomycin multiple interactions ISO RGD:11215 6480464 tautomycin inhibits the reaction [[Hydrogen Peroxide co-treated with Tetradecanoylphorbol Acetate] results in increased activity of RAF1 protein] CTD PMID:14623285 testosterone increases activity ISO RGD:737596 6480464 [Testosterone results in increased activity of RAF1 protein] which results in increased activity of MAP2K1 protein more ... CTD PMID:20372086 testosterone multiple interactions EXP 6480464 [FSHB protein co-treated with 1-Methyl-3-isobutylxanthine] inhibits the reaction [Testosterone promotes the reaction [RAF1 results in increased phosphorylation of MAP2K1 protein]] more ... CTD PMID:21177760 tetrahydropalmatine increases expression ISO RGD:737596 6480464 tetrahydropalmatine results in increased expression of RAF1 protein CTD PMID:20109541 thapsigargin multiple interactions ISO RGD:11215 6480464 Thapsigargin inhibits the reaction [cypermethrin results in increased phosphorylation of and results in increased activity of RAF1 protein] CTD PMID:29149324 thapsigargin decreases expression ISO RGD:737596 6480464 Thapsigargin results in decreased expression of RAF1 mRNA CTD PMID:22378314 tipifarnib increases expression EXP 6480464 tipifarnib results in increased expression of RAF1 mRNA CTD PMID:16403772 titanium dioxide increases phosphorylation ISO RGD:11215 6480464 titanium dioxide analog results in increased phosphorylation of RAF1 protein CTD PMID:25111187 trans-caffeic acid multiple interactions ISO RGD:737596 6480464 caffeic acid inhibits the reaction [Acetaminophen results in increased phosphorylation of RAF1 protein] CTD PMID:27720869 trans-caffeic acid multiple interactions ISO RGD:11215 6480464 caffeic acid inhibits the reaction [Acetaminophen results in increased phosphorylation of RAF1 protein] CTD PMID:27720869 tributylstannane multiple interactions ISO RGD:737596 6480464 tributyltin affects the expression of and results in increased phosphorylation of RAF1 protein CTD PMID:24038145 trichostatin A affects expression ISO RGD:737596 6480464 trichostatin A affects the expression of RAF1 mRNA CTD PMID:28542535 trimethyltin increases expression ISO RGD:11215 6480464 trimethyltin results in increased expression of RAF1 mRNA CTD PMID:20833246 troglitazone multiple interactions ISO RGD:11215 6480464 [troglitazone co-treated with Diethylnitrosamine] results in decreased expression of RAF1 mRNA CTD PMID:18597072 tunicamycin decreases expression ISO RGD:737596 6480464 Tunicamycin results in decreased expression of RAF1 mRNA CTD PMID:22378314 urethane multiple interactions ISO RGD:11215 6480464 tocopheryloxybutyric acid inhibits the reaction [Urethane promotes the reaction [RAF1 protein binds to HRAS protein]] more ... CTD PMID:11062179 ursodeoxycholic acid multiple interactions ISO RGD:737596 6480464 Ursodeoxycholic Acid inhibits the reaction [Deoxycholic Acid results in increased phosphorylation of and results in increased activity of RAF1 protein] CTD PMID:14747693 valproic acid affects expression ISO RGD:737596 6480464 Valproic Acid affects the expression of RAF1 mRNA CTD PMID:25979313 vemurafenib multiple interactions ISO RGD:737596 6480464 RAF1 protein affects the reaction [[KRAS protein mutant form affects the susceptibility to Vemurafenib] promotes the reaction [TNFRSF10B protein results in increased cleavage of CASP3 protein]] more ... CTD PMID:27222248 vitamin E multiple interactions ISO RGD:11215 6480464 Vitamin E inhibits the reaction [Urethane promotes the reaction [RAF1 protein binds to HRAS protein]] CTD PMID:11062179 vorinostat multiple interactions ISO RGD:737596 6480464 [17-(dimethylaminoethylamino)-17-demethoxygeldanamycin co-treated with vorinostat] results in decreased expression of RAF1 protein, [Bortezomib co-treated with vorinostat] results in decreased expression of RAF1 protein CTD PMID:12893773 , PMID:19440035 vorinostat decreases expression ISO RGD:737596 6480464 vorinostat results in decreased expression of RAF1 protein CTD PMID:12893773 more ... wortmannin multiple interactions ISO RGD:737596 6480464 wortmannin promotes the reaction [hydroxyflutamide results in increased phosphorylation of RAF1 protein], wortmannin promotes the reaction [ON123300 results in increased phosphorylation of RAF1 protein] CTD PMID:24568969 , PMID:28163245 zearalenone increases expression ISO RGD:11215 6480464 Zearalenone results in increased expression of RAF1 mRNA CTD PMID:29758222 zinc atom multiple interactions ISO RGD:11215 6480464 calphostin complex inhibits the reaction [Zinc promotes the reaction [OPRM1 protein binds to PRKCG protein binds to RAF1 protein]] more ... CTD PMID:21235400 zinc dichloride multiple interactions EXP 6480464 1 more ... CTD PMID:21575692 zinc dichloride increases phosphorylation EXP 6480464 zinc chloride results in increased phosphorylation of RAF1 protein CTD PMID:21575692 zinc(0) multiple interactions ISO RGD:11215 6480464 calphostin complex inhibits the reaction [Zinc promotes the reaction [OPRM1 protein binds to PRKCG protein binds to RAF1 protein]] more ... CTD PMID:21235400 zoledronic acid decreases expression ISO RGD:737596 6480464 zoledronic acid results in decreased expression of RAF1 protein CTD PMID:12799645
Gene-Chemical Interaction Annotations
