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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 3531
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Raf1
Name: Raf-1 proto-oncogene, serine/threonine kinase
Acc ID: CHEBI:28640
Term: lipoteichoic acid
Definition: A teichoic acid which is covalently bound to a lipid.
Chemical ID: MESH:C009900
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Raf1increases phosphorylationISORaf1 (Mus musculus)6480464CTDlipoteichoic acid results in increased phosphorylation of RAF1 proteinPMID:19573522
Raf1multiple interactionsISORaf1 (Mus musculus)6480464CTDPropofol inhibits the reaction [lipoteichoic acid results in increased phosphorylation of RAF1 protein]; TLR2 protein affects the reaction [lipoteichoic acid results in increased phosphorylation of RAF1 protein]PMID:19573522
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