HRAS (HRas proto-oncogene, GTPase) - Rat Genome Database

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Gene: HRAS (HRas proto-oncogene, GTPase) Homo sapiens
Symbol: HRAS
Name: HRas proto-oncogene, GTPase
RGD ID: 730881
HGNC Page HGNC:5173
Description: Enables GDP binding activity; GTP binding activity; and GTPase activity. Involved in several processes, including positive regulation of MAPK cascade; regulation of GTPase activity; and regulation of protein localization to membrane. Located in several cellular components, including GTPase complex; Golgi apparatus; and nucleoplasm. Is active in glutamatergic synapse. Implicated in several diseases, including Costello syndrome; autistic disorder; carcinoma (multiple); epidermal nevus; and large congenital melanocytic nevus. Biomarker of Alzheimer's disease; endometrial carcinoma; glioblastoma; liver disease (multiple); and urinary bladder cancer.
Type: protein-coding
RefSeq Status: REVIEWED
Previously known as: C-BAS/HAS; C-H-RAS; C-HA-RAS1; c-has/bas p21 protein; c-K-ras; c-Ki-ras; c-ras-Ki-2 activated oncogene; CTLO; GTP- and GDP-binding peptide B; GTPase HRas; GTPase KRas; H-Ras-1; H-RASIDX; ha-Ras; Ha-Ras1 proto-oncoprotein; HAMSV; Harvey rat sarcoma viral oncogene homolog; Harvey rat sarcoma viral oncoprotein; HRAS1; K-RAS; K-Ras 2; Ki-Ras; KRAS; KRAS2; N-RAS; p19 H-RasIDX protein; p21ras; Ras family small GTP binding protein H-Ras; RASH1; RASK2; transformation gene: oncogene HAMSV; transforming protein p21; v-Ha-ras Harvey rat sarcoma viral oncogene homolog
RGD Orthologs
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Allele / Splice: See ClinVar data
Is Marker For: Strains:   SD-Tg(CAG-HRAS*G12V)250Htsu  
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh3811532,242 - 535,576 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl11532,242 - 537,321 (-)EnsemblGRCh38hg38GRCh38
GRCh3711532,242 - 535,576 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 3611522,242 - 525,550 (-)NCBINCBI36Build 36hg18NCBI36
Build 3411522,242 - 525,550NCBI
Celera11594,708 - 598,010 (-)NCBICelera
Cytogenetic Map11p15.5NCBI
HuRef11346,981 - 349,115 (-)NCBIHuRef
CHM1_111529,852 - 534,465 (-)NCBICHM1_1
T2T-CHM13v2.011579,238 - 582,554 (-)NCBIT2T-CHM13v2.0
JBrowse: View Region in Genome Browser (JBrowse)