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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2827
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Hras
Name: HRas proto-oncogene, GTPase
Acc ID: CHEBI:16240
Term: hydrogen peroxide
Definition: An inorganic peroxide consisting of two hydroxy groups joined by a covalent oxygen-oxygen single bond.
Chemical ID: MESH:D006861
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Hrasincreases expressionISOHRAS (Homo sapiens)6480464CTDHydrogen Peroxide results in increased expression of HRAS mRNAPMID:11008122
Hrasmultiple interactionsISOHras (Mus musculus)6480464CTDHRAS protein affects the susceptibility to [Hydrogen Peroxide results in increased activity of MAPK1 protein]; HRAS protein affects the susceptibility to [Hydrogen Peroxide results in increased activity of MAPK3 protein]PMID:14975446
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