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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2827
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Hras
Name: HRas proto-oncogene, GTPase
Acc ID: CHEBI:16469
Term: 17beta-estradiol
Definition: The 17beta-isomer of estradiol.
Chemical ID: MESH:D004958
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Hrasaffects expressionISOHRAS (Homo sapiens)6480464CTDEstradiol affects the expression of HRAS mRNAPMID:21826169
Hrasincreases expressionISOHras (Mus musculus)6480464CTDEstradiol results in increased expression of HRAS mRNAPMID:22467019
Hrasincreases expressionISOHRAS (Homo sapiens)6480464CTDEstradiol results in increased expression of HRAS mRNAPMID:16051634 PMID:23094148
Hrasmultiple interactionsISOHRAS (Homo sapiens)6480464CTDdibenzoylmethane inhibits the reaction [Estradiol results in increased expression of HRAS mRNA]; Estradiol affects the reaction [HRAS protein results in increased susceptibility to 9,10-Dimethyl-1,2-benzanthracene]PMID:12117780 PMID:16051634
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