GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Hras | increases activity | EXP | | 6480464 | CTD | cordycepin results in increased activity of HRAS protein | PMID:22366198 | Hras | multiple interactions | EXP | | 6480464 | CTD | HRAS protein mutant form inhibits the reaction [cordycepin results in increased expression of CDK2 protein]; HRAS protein mutant form inhibits the reaction [cordycepin results in increased expression of CDK4 protein]; HRAS protein mutant form inhibits the reaction [cordycepin results in increased expression of CDKN1B protein]; HRAS protein mutant form inhibits the reaction [cordycepin results in increased phosphorylation of and results in increased activity of MAPK1 protein]; HRAS protein mutant form inhibits the reaction [cordycepin results in increased phosphorylation of and results in increased activity of MAPK3 protein] | PMID:22366198 | | ||||||||||||||||||||||
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