Hras (HRas proto-oncogene, GTPase)

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Gene: Hras (HRas proto-oncogene, GTPase) Chinchilla lanigera

Analyze

Symbol:

Hras

Name:

HRas proto-oncogene, GTPase

RGD ID:

8952216

Description:

ENCODES a protein that exhibits GDP binding (ortholog); GTP binding (ortholog); GTPase activity (ortholog); INVOLVED IN adipose tissue development (ortholog); cellular response to gamma radiation (ortholog); cellular senescence (ortholog); PARTICIPATES IN adenosine signaling pathway; endothelin signaling pathway; ephrin - ephrin receptor bidirectional signaling axis; ASSOCIATED WITH acute myeloid leukemia (ortholog); adenoid cystic carcinoma (ortholog); Alzheimer's disease (ortholog); FOUND IN cytosol (ortholog); glutamatergic synapse (ortholog); Golgi apparatus (ortholog)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

GTPase HRas; Harvey rat sarcoma viral oncogene homolog

RGD Orthologs

Alliance Genes

More Info

more info ...

Latest Assembly:

ChiLan1.0 - Chinchilla ChiLan1.0 Assembly

Position:

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955476	11,508,126 - 11,510,333 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955476	11,508,446 - 11,510,333 (+)	NCBI	ChiLan1.0	ChiLan1.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

acute myeloid leukemia (ISO)

adenoid cystic carcinoma (ISO)

Alzheimer's disease (ISO)

angiosarcoma (ISO)

Animal Mammary Neoplasms (ISO)

autistic disorder (ISO)

autoimmune hepatitis (ISO)

B-Cell Chronic Lymphocytic Leukemia (ISO)

bladder carcinoma (ISO)

Brain Neoplasms (ISO)

Breast Neoplasms (ISO)

carcinoma (ISO)

cardiofaciocutaneous syndrome (ISO)

Chanarin-Dorfman syndrome (ISO)

chronic lymphocytic leukemia (ISO)

Colorectal Neoplasms (ISO)

complex cortical dysplasia with other brain malformations (ISO)

Congenital Myopathy with Excess of Muscle Spindles (ISO)

Costello syndrome (ISO)

delta beta-thalassemia (ISO)

developmental and epileptic encephalopathy (ISO)

diabetic retinopathy (ISO)

disease of cellular proliferation (ISO)

Disease Progression (ISO)

early infantile epileptic encephalopathy (ISO)

endometrial carcinoma (ISO)

epidermal nevus (ISO)

esophageal carcinoma (ISO)

Experimental Diabetes Mellitus (ISO)

Experimental Liver Neoplasms (ISO)

Experimental Mammary Neoplasms (ISO)

Experimental Neoplasms (ISO)

Follicular Thyroid Cancer (ISO)

gastric adenocarcinoma (ISO)

genetic disease (ISO)

glioblastoma (ISO)

head and neck squamous cell carcinoma (ISO)

hepatocellular adenoma (ISO)

hepatocellular carcinoma (ISO)

Hereditary Neoplastic Syndromes (ISO)

high grade glioma (ISO)

Hydrops Fetalis (ISO)

Hypophosphatemic Rickets (ISO)

immunodeficiency 39 (ISO)

intellectual disability (ISO)

large congenital melanocytic nevus (ISO)

linear nevus sebaceous syndrome (ISO)

liver cancer (ISO)

liver carcinoma (ISO)

liver cirrhosis (ISO)

Liver Neoplasms (ISO)

lung adenocarcinoma (ISO)

Lung Neoplasms (ISO)

lung non-small cell carcinoma (ISO)

lung squamous cell carcinoma (ISO)

melanoma (ISO)

Mouth Neoplasms (ISO)

multiple myeloma (ISO)

myelodysplastic syndrome (ISO)

Nasopharyngeal Neoplasms (ISO)

Neoplasm Invasiveness (ISO)

Neoplastic Cell Transformation (ISO)

Neoplastic Processes (ISO)

neuroblastoma (ISO)

neuronal ceroid lipofuscinosis (ISO)

Noonan syndrome (ISO)

Noonan syndrome 3 (ISO)

obsessive-compulsive disorder (ISO)

ovarian cancer (ISO)

Ovarian Neoplasms (ISO)

ovarian serous cystadenocarcinoma (ISO)

pancreatic adenocarcinoma (ISO)

papillary renal cell carcinoma (ISO)

papilloma (ISO)

Paraproteinemias (ISO)

parathyroid adenoma (ISO)

Penile Neoplasms (ISO)

phobic disorder (ISO)

Pigmented Nevus (ISO)

plasma cell neoplasm (ISO)

pre-malignant neoplasm (ISO)

prostate adenocarcinoma (ISO)

Prostate Cancer, Hereditary, 1 (ISO)

Prostatic Neoplasms (ISO)

pulmonary valve stenosis (ISO)

RASopathy (ISO)

Recurrence (ISO)

rhabdomyosarcoma (ISO)

Salivary Gland Neoplasms (ISO)

Sebaceous Nevus Syndrome and Hemimegalencephaly (ISO)

seminoma (ISO)

skin benign neoplasm (ISO)

skin melanoma (ISO)

Skin Neoplasms (ISO)

spermatocytoma (ISO)

Splenic Neoplasms (ISO)

Sporadic Papillary Renal Cell Carcinoma (ISO)

squamous cell carcinoma (ISO)

Stomach Neoplasms (ISO)

T-cell non-Hodgkin lymphoma (ISO)

thymoma (ISO)

Thyroid Neoplasms (ISO)

Tongue Neoplasms (ISO)

transitional cell carcinoma (ISO)

Trichilemmoma (ISO)

urinary bladder cancer (ISO)

Urinary Bladder Neoplasm (ISO)

uterine cancer (ISO)

uterine carcinosarcoma (ISO)

Uterine Cervical Neoplasms (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

adipose tissue development (ISO)

cellular response to gamma radiation (ISO)

cellular senescence (ISO)

defense response to protozoan (ISO)

endocytosis (ISO)

fibroblast proliferation (ISO)

insulin receptor signaling pathway (ISO)

intrinsic apoptotic signaling pathway (ISO)

liver development (ISO)

myelination (ISO)

negative regulation of cell population proliferation (ISO)

negative regulation of gene expression (ISO)

negative regulation of neuron apoptotic process (ISO)

neuron apoptotic process (ISO)

oncogene-induced cell senescence (ISO)

positive regulation of cell migration (ISO)

positive regulation of cell population proliferation (ISO)

positive regulation of DNA replication (ISO)

positive regulation of epithelial cell proliferation (ISO)

positive regulation of ERK1 and ERK2 cascade (ISO)

positive regulation of fibroblast proliferation (ISO)

positive regulation of gene expression (ISO)

positive regulation of JNK cascade (ISO)

positive regulation of MAPK cascade (ISO)

positive regulation of miRNA metabolic process (ISO)

positive regulation of protein phosphorylation (ISO)

positive regulation of protein targeting to membrane (ISO)

positive regulation of Ras protein signal transduction (ISO)

positive regulation of ruffle assembly (ISO)

positive regulation of transcription by RNA polymerase II (ISO)

positive regulation of type II interferon production (ISO)

positive regulation of wound healing (ISO)

Ras protein signal transduction (ISO)

regulation of actin cytoskeleton organization (ISO)

regulation of cell cycle (ISO)

regulation of cell population proliferation (ISO)

regulation of long-term neuronal synaptic plasticity (ISO)

regulation of neurotransmitter receptor localization to postsynaptic specialization membrane (ISO)

regulation of transcription by RNA polymerase II (ISO)

response to isolation stress (ISO)

Schwann cell development (ISO)

small GTPase mediated signal transduction (ISO)

T cell receptor signaling pathway (ISO)

T-helper 1 type immune response (ISO)

Cellular Component

cytosol (ISO)

glutamatergic synapse (ISO)

Golgi apparatus (ISO)

GTPase complex (ISO)

nucleoplasm (ISO)

plasma membrane (ISO)

Molecular Function

GDP binding (ISO)

GTP binding (ISO)

GTPase activity (ISO)

protein binding (ISO)

protein-containing complex binding (ISO)

protein-membrane adaptor activity (ISO)

Molecular Pathway Annotations Click to see Annotation Detail View

adenosine signaling pathway (ISO)

endothelin signaling pathway (ISO)

ephrin - ephrin receptor bidirectional signaling axis (ISO)

epidermal growth factor/neuregulin signaling pathway (ISO)

erythropoietin signaling pathway (ISO)

Fc epsilon receptor mediated signaling pathway (ISO)

granulocyte-macrophage colony-stimulating factor signaling pathway (ISO)

insulin signaling pathway (ISO)

insulin-like growth factor signaling pathway (ISO)

interleukin-2 signaling pathway (ISO)

mTOR signaling pathway (ISO)

phosphatidylinositol 3-kinase class I signaling pathway (ISO)

platelet-derived growth factor signaling pathway (ISO)

syndecan signaling pathway (ISO)

the extracellular signal-regulated Raf/Mek/Erk signaling pathway (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Transitive Annotation Pipeline	Automated assignment of GO, PW and RDO ISO annotations across species
2.	OMIM Disease Annotation Pipeline	OMIM Disease Annotation Pipeline

Genomics

Comparative Map Data

Hras
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955476	11,508,126 - 11,510,333 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955476	11,508,446 - 11,510,333 (+)	NCBI	ChiLan1.0	ChiLan1.0

HRAS
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	11	532,242 - 535,576 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	11	532,242 - 537,321 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	11	532,242 - 535,576 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	11	522,242 - 525,550 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	11	522,242 - 525,550	NCBI
Celera	11	594,708 - 598,010 (-)	NCBI		Celera
Cytogenetic Map	11	p15.5	NCBI
HuRef	11	346,981 - 349,115 (-)	NCBI		HuRef
CHM1_1	11	529,852 - 534,465 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	11	579,238 - 582,554 (-)	NCBI		T2T-CHM13v2.0

Hras
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	7	140,770,839 - 140,773,938 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	7	140,769,018 - 140,773,918 (-)	Ensembl		GRCm39 Ensembl
GRCm38	7	141,189,934 - 141,194,019 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	7	141,189,105 - 141,194,005 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	7	148,375,833 - 148,379,903 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	7	141,042,668 - 141,044,260 (-)	NCBI		MGSCv36	mm8
Celera	7	140,983,643 - 140,987,701 (-)	NCBI		Celera
Cytogenetic Map	7	F5	NCBI
cM Map	7	86.48	NCBI

Hras
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mRatBN7.2	1	196,290,127 - 196,299,823 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	1	196,296,263 - 196,300,615 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	1	204,641,764 - 204,645,046 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	1	211,768,581 - 211,771,863 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	1	204,442,715 - 204,445,997 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	1	214,178,404 - 214,181,841 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	1	214,178,407 - 214,181,686 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	1	221,095,943 - 221,099,362 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	1	201,385,705 - 201,388,987 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	1	201,540,000 - 201,542,640 (-)	NCBI
Celera	1	193,930,281 - 193,933,583 (-)	NCBI		Celera
RH 3.4 Map	1	1437.21	RGD
Cytogenetic Map	1	q41	NCBI

HRAS
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1	11	2,126,936 - 2,130,261 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	11	537,488 - 540,810 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	11	568,305 - 571,078 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	11	568,305 - 571,078 (-)	Ensembl	panpan1.1		panPan2

HRAS
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	18	25,642,844 - 25,644,717 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	18	25,642,844 - 25,644,717 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	18	25,291,831 - 25,293,704 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	18	26,227,144 - 26,230,043 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	18	26,220,886 - 26,230,059 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	18	25,736,932 - 25,738,805 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	18	25,381,917 - 25,383,790 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	18	25,994,065 - 25,995,938 (-)	NCBI		UU_Cfam_GSD_1.0

Hras
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404947	375,371 - 378,065 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936888	375,377 - 377,958 (-)	Ensembl	SpeTri2.0
SpeTri2.0	NW_004936888	375,372 - 378,125 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

HRAS
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	2	299,660 - 302,501 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	2	299,662 - 302,539 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1

HRAS
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	1	343,613 - 345,782 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	1	343,506 - 346,637 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666038	97,407,188 - 97,410,502 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Hras
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624766	21,911,241 - 21,913,653 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624766	21,907,423 - 21,913,414 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Expression

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_005401836	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_005401837	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AGCD01055461	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	GBBH01092203	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSCLAT00000004039 ⟹ ENSCLAP00000003959

Type:

CODING

Position:

Chinchilla Assembly	Chr	Position (strand)	Source
ChiLan1.0 Ensembl	NW_004955476	11,508,126 - 11,510,333 (+)	Ensembl

RefSeq Acc Id:

ENSCLAT00000004040 ⟹ ENSCLAP00000003960

Type:

CODING

Position:

Chinchilla Assembly	Chr	Position (strand)	Source
ChiLan1.0 Ensembl	NW_004955476	11,508,494 - 11,509,833 (+)	Ensembl

RefSeq Acc Id:

XM_005401836 ⟹ XP_005401893

Type:

CODING

Position:

Chinchilla Assembly	Chr	Position (strand)	Source
ChiLan1.0	NW_004955476	11,508,446 - 11,510,333 (+)	NCBI

Sequence:

show sequence

GTGGGGCAGGAGCCCCCAGTGCCCTGAGCGTCGGCCCCTGGAGGAGCCATGACGGAGTACAAGC
TTGTGGTGGTGGGCGCAGGAGGCGTGGGGAAGAGCGCCCTGACCATCCAGCTGATCCAGAACCA
CTTTGTGGACGAGTATGACCCTACCATAGAGGACTCATACCGGAAGCAGGTGGTCATTGATGGG
GAGACGTGCCTGCTGGATATCTTGGACACAGCGGGTCAGGAGGAGTATAGTGCCATGCGGGACC
AGTACATGCGCACTGGGGAGGGCTTCCTTTGTGTGTTCGCCATCAACAACACCAAGTCTTTTGA
GGACATCCATCAATACAGGGAGCAGATCAAGCGGGTGAAGGACTCAGATGATGTGCCCATGGTG
CTGGTGGGGAATAAATGTGACCTGGCTGCACGCACTGTGGAGTCTCGGCAGGCCCAGGACCTCG
CCCGCAGTTACAGCATTCCCTACATCGAGACATCAGCCAAGACCCGCCAGGGCGTAGAAGATGC
TTTCTATACACTAGTTCGTGAGATCCGGCAGCACAAGCTGCGGAAGCTGAACCCTCCAGATGAA
AGTGGGCCAGGATGTATGAGCTGCAAGTGTGTGCTGTCCTGATCCAGGTGAGCAGGGCCCAGCC
AGCTCCCTGAGCCACAGCCCTGGCCAGCCAAGCCAAGCTGCACGTGTATTCTGGTGCTCGCGGG
CTCCCTGAACCTGCTGGTTCCCCTGCCTACGATCAGTGGCATCCTTTGTGCTCCACCCTGGCCC
AGGCTCAGGACACAGAGGTGCCGGATGCAGGGAGGAGGTGCAGACGGAAGGAAGCAAGGAGGGA
AGGAAGGAAGGAAGTGCCACTGGAGCCCGGCCAGCCCAGGGATGGTGGACAGAGGCGACCACAG
ACCCTCCCGTGGATGCTTTGCAGACTGTCATGAACTGTCCCAAAAACCACTGGCACCCCAGCCC
CGACTCCCCTCCCAGCCCCTGCAGCCTCTGACAGGTGCAGGTTGATTCACAGTAAATTATTTGA
TGGTCTTGA

hide sequence

RefSeq Acc Id:

XM_005401837 ⟹ XP_005401894

Type:

CODING

Position:

Chinchilla Assembly	Chr	Position (strand)	Source
ChiLan1.0	NW_004955476	11,508,446 - 11,509,891 (+)	NCBI

Sequence:

show sequence

GTGGGGCAGGAGCCCCCAGTGCCCTGAGCGTCGGCCCCTGGAGGAGCCATGACGGAGTACAAGC
TTGTGGTGGTGGGCGCAGGAGGCGTGGGGAAGAGCGCCCTGACCATCCAGCTGATCCAGAACCA
CTTTGTGGACGAGTATGACCCTACCATAGAGGACTCATACCGGAAGCAGGTGGTCATTGATGGG
GAGACGTGCCTGCTGGATATCTTGGACACAGCGGGTCAGGAGGAGTATAGTGCCATGCGGGACC
AGTACATGCGCACTGGGGAGGGCTTCCTTTGTGTGTTCGCCATCAACAACACCAAGTCTTTTGA
GGACATCCATCAATACAGGGAGCAGATCAAGCGGGTGAAGGACTCAGATGATGTGCCCATGGTG
CTGGTGGGGAATAAATGTGACCTGGCTGCACGCACTGTGGAGTCTCGGCAGGCCCAGGACCTCG
CCCGCAGTTACAGCATTCCCTACATCGAGACATCAGCCAAGACCCGCCAGGGCAGCCGCTCTGG
CTCTGGCTCCAGCTCCGGGACCCTCTGGGACCCATGTGACCCATGTGACCCATCGGCCCCCATG
CTGGCGTAGAAGATGCTTTCTATACACTAGTTCGTGAGATCCGGCAGCACAAGCTGCGGAAGCT
GAACCCTCCAGATGAAAGTGGGCCAGGATGT

hide sequence

Protein Sequences


Protein RefSeqs	XP_005401893	(Get FASTA)	NCBI Sequence Viewer
	XP_005401894	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:	XP_005401893 ⟸ XM_005401836
- Peptide Label:	isoform X1
- UniProtKB:	A0A8C2YJV0 (UniProtKB/TrEMBL)
- Sequence:	show sequence MTEYKLVVVGAGGVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETCLLDILDTAGQEEY SAMRDQYMRTGEGFLCVFAINNTKSFEDIHQYREQIKRVKDSDDVPMVLVGNKCDLAARTVESR QAQDLARSYSIPYIETSAKTRQGVEDAFYTLVREIRQHKLRKLNPPDESGPGCMSCKCVLS hide sequence

RefSeq Acc Id:	XP_005401894 ⟸ XM_005401837
- Peptide Label:	isoform X2
- UniProtKB:	A0A8C2UR14 (UniProtKB/TrEMBL)
- Sequence:	show sequence MTEYKLVVVGAGGVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETCLLDILDTAGQEEY SAMRDQYMRTGEGFLCVFAINNTKSFEDIHQYREQIKRVKDSDDVPMVLVGNKCDLAARTVESR QAQDLARSYSIPYIETSAKTRQGSRSGSGSSSGTLWDPCDPCDPSAPMLA hide sequence

RefSeq Acc Id:

ENSCLAP00000003959 ⟸ ENSCLAT00000004039

RefSeq Acc Id:

ENSCLAP00000003960 ⟸ ENSCLAT00000004040

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSCLAG00000002823	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein	ENSCLAP00000003959	ENTREZGENE
	ENSCLAP00000003959.1	UniProtKB/TrEMBL
	ENSCLAP00000003960	ENTREZGENE
	ENSCLAP00000003960.1	UniProtKB/TrEMBL
Ensembl Transcript	ENSCLAT00000004039	ENTREZGENE
	ENSCLAT00000004039.1	UniProtKB/TrEMBL
	ENSCLAT00000004040	ENTREZGENE
	ENSCLAT00000004040.1	UniProtKB/TrEMBL
Gene3D-CATH	3.40.50.300	UniProtKB/TrEMBL
InterPro	P-loop_NTPase	UniProtKB/TrEMBL
	Small_GTP-bd_dom	UniProtKB/TrEMBL
	Small_GTPase	UniProtKB/TrEMBL
	Small_GTPase_Ras-type	UniProtKB/TrEMBL
NCBI Gene	Hras	ENTREZGENE
PANTHER	GTPASE HRAS	UniProtKB/TrEMBL
	PTHR24070	UniProtKB/TrEMBL
Pfam	Ras	UniProtKB/TrEMBL
PRINTS	RASTRNSFRMNG	UniProtKB/TrEMBL
PROSITE	RAB	UniProtKB/TrEMBL
	RAS	UniProtKB/TrEMBL
	RHO	UniProtKB/TrEMBL
SMART	RAB	UniProtKB/TrEMBL
	RAS	UniProtKB/TrEMBL
	RHO	UniProtKB/TrEMBL
Superfamily-SCOP	SSF52540	UniProtKB/TrEMBL
UniProt	A0A8C2UR14	ENTREZGENE, UniProtKB/TrEMBL
	A0A8C2YJV0	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2016-08-03	Hras	HRas proto-oncogene, GTPase		Harvey rat sarcoma viral oncogene homolog	Symbol and/or name change	5135510	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Disease Annotations - OMIM

RGD Manual Annotations

Imported Annotations - SMPDB

Imported Annotations - PID (archival)

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Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Disease Annotations - OMIM

RGD Manual Annotations

Imported Annotations - SMPDB

Imported Annotations - PID (archival)