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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2827
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Hras
Name: HRas proto-oncogene, GTPase
Acc ID: CHEBI:17301
Term: glucaric acid
Definition: A hexaric acid derived by oxidation of sugar such as glucose with nitric acid.
Chemical ID: MESH:D005937
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Hrasmultiple interactionsISORGD:107306480464CTD[Glucaric Acid co-treated with Plant Extracts] inhibits the reaction [9 10-Dimethyl-1 2-benzanthracene results in increased mutagenesis of HRAS gene] [Glucaric Acid co-treated with resveratrol] inhibits the reaction [9 10-Dimethyl-1 2-benzanthracene results in increased mutagenesis of HRAS gene]

PMID:20103723
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