Cdca5 (cell division cycle associated 5) - Rat Genome Database

Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Gene: Cdca5 (cell division cycle associated 5) Rattus norvegicus
Analyze
Symbol: Cdca5
Name: cell division cycle associated 5
RGD ID: 1560863
Description: Predicted to be involved in chromosome organization; double-strand break repair; and positive regulation of exit from mitosis. Predicted to be located in chromatin; cytoplasm; and nucleoplasm. Predicted to be active in nucleus. Orthologous to human CDCA5 (cell division cycle associated 5); INTERACTS WITH acetamide; acrylamide; bisphenol A.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: hypothetical protein LOC684771; LOC499310; LOC684771; RGD1560863; similar to cell division cycle associated 5; sororin
RGD Orthologs
Human
Mouse
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81212,807,863 - 212,821,313 (+)NCBIGRCr8
mRatBN7.21203,378,550 - 203,392,027 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1203,378,577 - 203,392,023 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1211,731,627 - 211,745,181 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01218,823,942 - 218,837,392 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01211,515,011 - 211,528,461 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01221,448,661 - 221,462,235 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1221,448,661 - 221,462,233 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01228,384,097 - 228,394,997 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41210,247,351 - 210,247,881 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1200,912,264 - 200,925,714 (+)NCBICelera
Cytogenetic Map1q43NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
1,1-dichloroethene  (ISO)
1,2-dimethylhydrazine  (ISO)
17alpha-ethynylestradiol  (ISO)
17beta-estradiol  (ISO)
2,2',4,4',5,5'-hexachlorobiphenyl  (ISO)
2,2',5,5'-tetrachlorobiphenyl  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (ISO)
2-palmitoylglycerol  (ISO)
3,3',4,4',5-pentachlorobiphenyl  (ISO)
3-isobutyl-1-methyl-7H-xanthine  (ISO)
3-methylcholanthrene  (ISO)
5-fluorouracil  (ISO)
acetamide  (EXP)
acrylamide  (EXP)
aflatoxin B1  (ISO)
all-trans-retinoic acid  (ISO)
antimycin A  (ISO)
aristolochic acid A  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
arsenite(3-)  (ISO)
azathioprine  (ISO)
benzo[a]pyrene  (ISO)
benzo[a]pyrene diol epoxide I  (ISO)
benzo[b]fluoranthene  (ISO)
beta-naphthoflavone  (ISO)
bis(2-chloroethyl) sulfide  (ISO)
bisphenol A  (EXP,ISO)
cadmium atom  (ISO)
caffeine  (ISO)
calcitriol  (ISO)
cannabidiol  (ISO)
carbon nanotube  (ISO)
CGP 52608  (ISO)
choline  (ISO)
chromium(6+)  (ISO)
cisplatin  (ISO)
copper atom  (EXP)
copper(0)  (EXP)
coumarin  (ISO)
coumestrol  (ISO)
cycloheximide  (ISO)
cyclosporin A  (ISO)
DDE  (ISO)
dexamethasone  (ISO)
diazinon  (EXP)
dibenz[a,h]anthracene  (ISO)
Dibutyl phosphate  (ISO)
dibutyl phthalate  (ISO)
diclofenac  (ISO)
dioxygen  (ISO)
doxorubicin  (ISO)
endosulfan  (EXP)
Enterolactone  (ISO)
folic acid  (ISO)
FR900359  (ISO)
genistein  (ISO)
indometacin  (ISO)
ivermectin  (ISO)
L-methionine  (ISO)
leflunomide  (ISO)
menadione  (ISO)
methyl methanesulfonate  (ISO)
N-nitrosodiethylamine  (ISO)
nickel atom  (ISO)
nickel dichloride  (EXP)
niclosamide  (ISO)
ozone  (ISO)
palbociclib  (ISO)
paracetamol  (EXP,ISO)
PCB138  (ISO)
perfluorooctanoic acid  (ISO)
phenobarbital  (ISO)
phytoestrogen  (ISO)
pirinixic acid  (ISO)
potassium dichromate  (ISO)
propanal  (ISO)
quercetin  (ISO)
resveratrol  (ISO)
silicon dioxide  (ISO)
sodium arsenite  (ISO)
sunitinib  (ISO)
T-2 toxin  (EXP)
tacrolimus hydrate  (ISO)
testosterone  (ISO)
tetrachloromethane  (ISO)
thioacetamide  (EXP)
titanium dioxide  (ISO)
trichloroethene  (ISO)
trimellitic anhydride  (ISO)
troglitazone  (ISO)
trovafloxacin  (ISO)
urethane  (ISO)
valproic acid  (ISO)
zinc atom  (ISO)
zinc(0)  (ISO)
zoledronic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
chromatin  (ISO)
cytoplasm  (ISO)
nucleoplasm  (ISO)
nucleus  (IBA,ISO)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:12477932   PMID:15837422   PMID:17349791   PMID:21111234   PMID:22833568   PMID:23548868   PMID:23920377  


Genomics

Comparative Map Data
Cdca5
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81212,807,863 - 212,821,313 (+)NCBIGRCr8
mRatBN7.21203,378,550 - 203,392,027 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1203,378,577 - 203,392,023 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1211,731,627 - 211,745,181 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01218,823,942 - 218,837,392 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01211,515,011 - 211,528,461 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01221,448,661 - 221,462,235 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1221,448,661 - 221,462,233 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01228,384,097 - 228,394,997 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41210,247,351 - 210,247,881 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1200,912,264 - 200,925,714 (+)NCBICelera
Cytogenetic Map1q43NCBI
CDCA5
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381165,061,093 - 65,084,040 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1165,066,300 - 65,084,164 (-)EnsemblGRCh38hg38GRCh38
GRCh371164,844,925 - 64,851,512 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361164,601,503 - 64,608,100 (-)NCBINCBI36Build 36hg18NCBI36
Build 341164,601,502 - 64,608,100NCBI
Celera1162,171,226 - 62,177,913 (-)NCBICelera
Cytogenetic Map11q13.1NCBI
HuRef1161,171,560 - 61,178,247 (-)NCBIHuRef
CHM1_11164,728,627 - 64,735,313 (-)NCBICHM1_1
T2T-CHM13v2.01165,054,375 - 65,077,318 (-)NCBIT2T-CHM13v2.0
Cdca5
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39196,135,127 - 6,141,803 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl196,135,013 - 6,141,807 (+)EnsemblGRCm39 Ensembl
GRCm38196,085,097 - 6,091,773 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl196,084,983 - 6,091,777 (+)EnsemblGRCm38mm10GRCm38
MGSCv37196,085,097 - 6,091,773 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36196,085,097 - 6,091,773 (+)NCBIMGSCv36mm8
Celera195,957,560 - 5,964,236 (+)NCBICelera
Cytogenetic Map19ANCBI
cM Map194.34NCBI
Cdca5
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_00495542220,114,565 - 20,129,679 (+)NCBIChiLan1.0ChiLan1.0
CDCA5
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11852,115,081 - 52,129,223 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1852,115,203 - 52,120,817 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1850,723,160 - 50,736,970 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01853,156,720 - 53,170,506 (+)NCBIROS_Cfam_1.0
UMICH_Zoey_3.11852,251,940 - 52,258,937 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01851,825,978 - 51,839,752 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01852,620,789 - 52,634,766 (+)NCBIUU_Cfam_GSD_1.0
Cdca5
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244049477,842,550 - 7,856,508 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365994,284,958 - 4,291,874 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365994,285,007 - 4,291,875 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CDCA5
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl27,103,673 - 7,113,202 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.127,103,648 - 7,112,772 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.226,235,704 - 6,251,945 (+)NCBISscrofa10.2Sscrofa10.2susScr3
CDCA5
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.119,151,503 - 9,157,412 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl19,151,712 - 9,157,456 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666038106,533,173 - 106,538,620 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Cdca5
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462476721,321,286 - 21,327,780 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:181
Count of miRNA genes:152
Interacting mature miRNAs:162
Transcripts:ENSRNOT00000072493
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1578778Pur4Proteinuria QTL 43.30.003urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)1160111531262090437Rat
1354646Kidm18Kidney mass QTL 185.7kidney mass (VT:0002707)calculated kidney weight (CMO:0000160)1160573753266453731Rat
1357335Bw39Body weight QTL 393.3body mass (VT:0001259)body weight (CMO:0000012)1207243873252243873Rat
1354652Kidm20Kidney mass QTL 204.3kidney mass (VT:0002707)calculated kidney weight (CMO:0000160)1186658830266453731Rat
2293674Bss39Bone structure and strength QTL 397.10.0001femur strength trait (VT:0010010)femur total energy absorbed before break (CMO:0001677)1210980612255980612Rat
1354653Despr9Despair related QTL 90.00019locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)1177339686222339686Rat
2293673Bss27Bone structure and strength QTL 2718.630.0001femur morphology trait (VT:0000559)femur midshaft cortical cross-sectional area (CMO:0001663)1181059071226059071Rat
2293677Bss41Bone structure and strength QTL 419.380.0001lumbar vertebra size trait (VT:0010518)lumbar vertebra cross-sectional area (CMO:0001689)1181059071226059071Rat
1549830Bss1Bone structure and strength QTL 14.8femur strength trait (VT:0010010)femur ultimate force (CMO:0001675)1182039247227039247Rat
70163Bw20Body weight QTL 205.1body mass (VT:0001259)body weight (CMO:0000012)1183564652228564652Rat
1600395Niddm69Non-insulin dependent diabetes mellitus QTL 694.140.0002blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)1205233991267096252Rat
1354624Cm35Cardiac mass QTL355.7heart left ventricle mass (VT:0007031)calculated heart weight (CMO:0000073)1186658830266453731Rat
1600396Niddm68Non-insulin dependent diabetes mellitus QTL 684.970.0003blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)1205233991267096252Rat
1600397Edcs4Endometrial carcinoma susceptibility QTL 42.2uterus morphology trait (VT:0001120)percentage of study population developing endometrioid carcinoma during a period of time (CMO:0001759)1176288899270518180Rat
631838Niddm36Non-insulin dependent diabetes mellitus QTL 360.01insulin secretion trait (VT:0003564)calculated pancreatic islet insulin release measurement (CMO:0001217)1193964073238964073Rat
1549837Hcar15Hepatocarcinoma resistance QTL 150.05liver integrity trait (VT:0010547)liver tumorous lesion number (CMO:0001068)1162548015270518180Rat
2293689Bss47Bone structure and strength QTL 477.250.0001lumbar vertebra size trait (VT:0010518)lumbar vertebra trabecular cross-sectional area (CMO:0001692)1181059071226059071Rat
1600388Niddm67Non-insulin dependent diabetes mellitus QTL 675.840.000004blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)1205233991267096252Rat
2293694Bss38Bone structure and strength QTL 387.050.0001femur strength trait (VT:0010010)femur stiffness (CMO:0001674)1210980612255980612Rat
61341Bp26Blood pressure QTL 26arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1139442053223964440Rat
1598853Memor3Memory QTL 34.5exploratory behavior trait (VT:0010471)total horizontal distance resulting from voluntary locomotion in an experimental apparatus (CMO:0001443)1152919152268496042Rat
1578759Uae30Urinary albumin excretion QTL 303.30.003urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)1160111531262090437Rat
2293693Bss22Bone structure and strength QTL 2233.520.0001femur morphology trait (VT:0000559)femur cross-sectional area (CMO:0001661)1181059071226059071Rat
1358902Bw47Body weight QTL 471.67body mass (VT:0001259)body weight (CMO:0000012)199645382221502378Rat
2300161Bmd43Bone mineral density QTL 438.40.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)1181059071226059071Rat
1300145Rf7Renal function QTL 72.96urine creatinine amount (VT:0010540)urine creatinine level (CMO:0000125)1194575422239575422Rat
61347Bp197Blood pressure QTL 1974.2arterial blood pressure trait (VT:2000000)blood pressure measurement (CMO:0000003)1168063662213063662Rat
8655655Arrd2Age-related retinal degeneration QTL 27.79retinal layer morphology trait (VT:0003727)percentage of study population developing retinopathy during a period of time (CMO:0002453)1193400541238400541Rat
1358898Bp255Blood pressure QTL 2553.6arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1200449456256003563Rat
631214Bw61Body weight QTL613.40.0001intramuscular adipose amount (VT:0010044)intramuscular fat area (CMO:0001162)1182535316227535316Rat
7771612Cm80Cardiac mass QTL 808.4heart left ventricle mass (VT:0007031)heart left ventricle weight (CMO:0000776)1146080545243492863Rat
731168Bp154Blood pressure QTL 1543.4arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1103779152223964440Rat
731175Uae20Urinary albumin excretion QTL 203.50.0018urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)1207163993269633915Rat
2300175Bmd40Bone mineral density QTL 4015.40.0001femur mineral mass (VT:0010011)bone mineral density (CMO:0001226)1210980612255980612Rat
2300174Bmd42Bone mineral density QTL 428.40.0001lumbar vertebra mineral mass (VT:0010511)bone mineral density (CMO:0001226)1181059071226059071Rat
737828Hcas3Hepatocarcinoma susceptibility QTL 34.9liver integrity trait (VT:0010547)liver tumorous lesion volume to total liver volume ratio (CMO:0001082)1153679879232414077Rat
1354661Bw33Body weight QTL 335.2body mass (VT:0001259)body weight (CMO:0000012)1160573753266453731Rat
1358886Bp260Blood pressure QTL 2603.67arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1160574007235238518Rat
2293654Bss30Bone structure and strength QTL 3032.650.0001femur strength trait (VT:0010010)femur midshaft polar moment of inertia (CMO:0001669)1181059071226059071Rat
2293655Bss36Bone structure and strength QTL 3610.660.0001femur strength trait (VT:0010010)femur ultimate force (CMO:0001675)1210980612255980612Rat
1298084Thym4Thymus enlargement QTL 410.68thymus mass (VT:0004954)thymus weight to body weight ratio (CMO:0000612)1207243873252243873Rat
724531Uae5Urinary albumin excretion QTL 54urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)1160111426262090599Rat
2300187Bmd41Bone mineral density QTL 418.90.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)1181059071226059071Rat
2314011Gluco56Glucose level QTL 56blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)1209203273254203273Rat
8552891Epfw5Epididymal fat weight QTL 54.4epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)1202543537247543537Rat
1354580Scort1Serum corticosterone level QTL 13.4blood corticosterone amount (VT:0005345)blood corticosterone level (CMO:0001172)1154961463266453731Rat
1358292Cm37Cardiac mass QTL 376.28e-07heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)1205674651250674651Rat
61376Bp42Blood pressure QTL 4223.4arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1207243873252243873Rat
634313Niddm43Non-insulin dependent diabetes mellitus QTL 43blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)1208479811269633915Rat
634312Bp143Blood pressure QTL 14330.0002arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1203300512229359342Rat
1358294Bw37Body weight QTL 3750.000011body mass (VT:0001259)body weight (CMO:0000012)1180739993225739993Rat
724559Pancm1Pancreatic morphology QTL 17.1islet of Langerhans morphology trait (VT:0005215)pancreatic islet damage composite score (CMO:0001156)1191190115223964326Rat
2312420Pur17Proteinuria QTL 177.10.0001urine protein amount (VT:0005160)urine total protein excretion rate (CMO:0000756)1172718770228180370Rat
10059600Bp378Blood pressure QTL 3783.080.05arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1186298393231298393Rat
1358916Kidm22Kidney mass QTL 223.32kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)1212738576257738576Rat
2312564Glom18Glomerulus QTL 182.40.003kidney glomerulus morphology trait (VT:0005325)index of glomerular damage (CMO:0001135)1194786607262083703Rat
634321Hc1Hypercalciuria QTL 12.91urine calcium amount (VT:0002985)urine calcium excretion rate (CMO:0000763)1188241285250779312Rat
2292218Kidm35Kidney mass QTL 35kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)1208798288253798288Rat
724562Rends1Renal damage susceptibility QTL 10.05kidney glomerulus integrity trait (VT:0010546)index of glomerular damage (CMO:0001135)1139442053223964440Rat
1300168Bp170Blood pressure QTL 1702.76arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1192995199237995199Rat
61403Niddm4Non-insulin dependent diabetes mellitus QTL 4blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)1201464383246464383Rat
2292222Bp307Blood pressure QTL 3073.060.0014arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1186298393231298393Rat
2292220Bp306Blood pressure QTL 3063.470.00087arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1186298393231298393Rat
1641926Teswt2Testicular weight QTL 22.82testis mass (VT:1000644)both testes wet weight (CMO:0000175)1203675682248675682Rat
631658Cm7Cardiac mass QTL 75.320.0001aorta mass (VT:0002845)aorta weight (CMO:0000076)1205674651250674651Rat
1600380Niddm70Non-insulin dependent diabetes mellitus QTL 703.10.0008blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)1185979875230979875Rat
1354610Bw34Body weight QTL 344.1body mass (VT:0001259)body weight (CMO:0000012)1160573753266453731Rat
1582206Kidm33Kidney mass QTL 336.9kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)1197807365233480676Rat
2293700Bmd27Bone mineral density QTL 276.60.0001femur mineral mass (VT:0010011)trabecular volumetric bone mineral density (CMO:0001729)1210980612255980612Rat
2293701Bmd34Bone mineral density QTL 348.30.0001femur strength trait (VT:0010010)femoral neck ultimate force (CMO:0001703)1210980612255980612Rat
8655855Arrd3Age-related retinal degeneration QTL 33.07lens clarity trait (VT:0001304)cataract incidence/prevalence measurement (CMO:0001585)1193400541238400541Rat
634338Hcar4Hepatocarcinoma resistance QTL 44.6liver integrity trait (VT:0010547)liver tumorous lesion number to liver area ratio (CMO:0001210)1202851915223964440Rat
6480783Insul19Insulin level QTL 194.33blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)1203300512213659238Rat
6903303Scl34Serum cholesterol QTL 342.50.0033blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)1173363824227535316Rat
1600374Mcs17Mammary carcinoma susceptibility QTL 173mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)1207099883252099883Rat
1600363Hc6Hypercalciuria QTL 62.7urine calcium amount (VT:0002985)urine calcium excretion rate (CMO:0000763)1210980612255980612Rat
2293083Iddm25Insulin dependent diabetes mellitus QTL 254.18blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)1191260175236260175Rat
1354606Bp246Blood pressure QTL 2463.6arterial blood pressure trait (VT:2000000)pulse pressure (CMO:0000292)1111949780228180370Rat
738032Hcas5Hepatocarcinoma susceptibility QTL 53.12liver integrity trait (VT:0010547)liver tumorous lesion number (CMO:0001068)1185857683270518180Rat
2325727Pia41Pristane induced arthritis QTL 41joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1188241285233241285Rat
7394701Uae46Urinary albumin excretion QTL 463.60.0056urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)1210980612255980612Rat

Markers in Region
RH127184  
Rat AssemblyChrPosition (strand)SourceJBrowse
Celera1200,918,021 - 200,918,270UniSTS
RH127507  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21204,747,871 - 204,748,051 (-)MAPPERmRatBN7.2
mRatBN7.21204,747,871 - 204,748,051 (+)MAPPERmRatBN7.2
Rnor_6.01222,809,846 - 222,810,025NCBIRnor6.0
Rnor_6.01221,454,663 - 221,454,842NCBIRnor6.0
Rnor_5.01229,797,092 - 229,797,271UniSTSRnor5.0
Rnor_5.01228,390,099 - 228,390,278UniSTSRnor5.0
RGSC_v3.41210,246,255 - 210,246,434UniSTSRGSC3.4
Celera1202,274,760 - 202,274,939UniSTS
Celera1200,918,138 - 200,918,317UniSTS
RH 3.4 Map11521.1UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 111 90 89 58 25 58 6 217 97 91 45 60 31

Sequence


Ensembl Acc Id: ENSRNOT00000072493   ⟹   ENSRNOP00000064620
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1203,378,577 - 203,392,023 (+)Ensembl
Rnor_6.0 Ensembl1221,448,661 - 221,462,233 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000113195   ⟹   ENSRNOP00000081071
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1203,378,582 - 203,384,670 (+)Ensembl
RefSeq Acc Id: NM_001115042   ⟹   NP_001108514
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81212,807,863 - 212,821,313 (+)NCBI
mRatBN7.21203,378,577 - 203,392,027 (+)NCBI
Rnor_6.01221,448,661 - 221,462,235 (+)NCBI
Rnor_5.01228,384,097 - 228,394,997 (+)NCBI
RGSC_v3.41210,247,351 - 210,247,881 (-)ENTREZGENE
Celera1200,912,264 - 200,925,714 (+)ENTREZGENE
Sequence:
RefSeq Acc Id: XM_008760176   ⟹   XP_008758398
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81212,807,877 - 212,813,959 (+)NCBI
mRatBN7.21203,378,550 - 203,384,673 (+)NCBI
Rnor_6.01221,448,666 - 221,454,885 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008760177   ⟹   XP_008758399
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81212,817,832 - 212,821,313 (+)NCBI
mRatBN7.21203,388,237 - 203,392,027 (+)NCBI
Rnor_6.01221,458,453 - 221,462,235 (+)NCBI
Sequence:
RefSeq Acc Id: NP_001108514   ⟸   NM_001115042
- UniProtKB: B0BN32 (UniProtKB/TrEMBL),   M0R5F5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_008758398   ⟸   XM_008760176
- Peptide Label: isoform X1
- UniProtKB: A0A8I5ZR80 (UniProtKB/TrEMBL),   A6HZD5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_008758399   ⟸   XM_008760177
- Peptide Label: isoform X2
- UniProtKB: A6HZD7 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000064620   ⟸   ENSRNOT00000072493
Ensembl Acc Id: ENSRNOP00000081071   ⟸   ENSRNOT00000113195

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-M0R5F5-F1-model_v2 AlphaFold M0R5F5 1-454 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13690688
Promoter ID:EPDNEW_R1212
Type:initiation region
Name:Cdca5_1
Description:cell division cycle associated 5
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01221,448,730 - 221,448,790EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1560863 AgrOrtholog
BioCyc Gene G2FUF-56620 BioCyc
Ensembl Genes ENSRNOG00000046635 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000072493.3 UniProtKB/TrEMBL
  ENSRNOT00000113195.1 UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7111047 IMAGE-MGC_LOAD
  IMAGE:8369770 IMAGE-MGC_LOAD
InterPro Sororin UniProtKB/TrEMBL
KEGG Report rno:684771 UniProtKB/TrEMBL
MGC_CLONE MGC:187653 IMAGE-MGC_LOAD
  MGC:188023 IMAGE-MGC_LOAD
NCBI Gene Cdca5 ENTREZGENE
PANTHER PTHR31092 UniProtKB/TrEMBL
  SORORIN UniProtKB/TrEMBL
Pfam Sororin UniProtKB/TrEMBL
PhenoGen Cdca5 PhenoGen
RatGTEx ENSRNOG00000046635 RatGTEx
UniProt A0A8I5ZR80 ENTREZGENE, UniProtKB/TrEMBL
  A6HZD5 ENTREZGENE, UniProtKB/TrEMBL
  A6HZD7 ENTREZGENE, UniProtKB/TrEMBL
  B0BN32 ENTREZGENE, UniProtKB/TrEMBL
  M0R5F5 ENTREZGENE
UniProt Secondary M0R5F5 UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2011-09-08 Cdca5  cell division cycle associated 5  LOC684771  similar to cell division cycle associated 5  Data merged from RGD:1586724 737654 APPROVED
2008-02-28 Cdca5  cell division cycle associated 5  RGD1560863_predicted  similar to cell division cycle associated 5 (predicted)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-11-19 LOC684771  similar to cell division cycle associated 5      Symbol and Name status set to provisional 70820 PROVISIONAL
2006-03-07 RGD1560863_predicted  similar to cell division cycle associated 5 (predicted)  LOC499310  similar to cell division cycle associated 5  Symbol and Name status set to approved 1299863 APPROVED
2006-02-09 LOC499310  similar to cell division cycle associated 5      Symbol and Name status set to provisional 70820 PROVISIONAL