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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1560863
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Cdca5
Name: cell division cycle associated 5
Acc ID: CHEBI:25812
Term: ozone
Definition: An elemental molecule with formula O3. An explosive, pale blue gas (b.p. -112degreeC) that has a characteristic, pungent odour, it is continuously produced in the upper atmosphere by the action of solar ultraviolet radiation on atmospheric oxygen. It is an antimicrobial agent used in the production of bottled water, as well as in the treatment of meat, poultry and other foodstuffs.
Chemical ID: MESH:D010126
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Cdca5increases expressionISOCdca5 (Mus musculus)6480464CTDOzone results in increased expression of CDCA5 mRNAPMID:33026818
Cdca5multiple interactionsISOCdca5 (Mus musculus)6480464CTD[Air Pollutants results in increased abundance of [Ozone co-treated with Soot]] which results in increased expression of CDCA5 mRNA; [Air Pollutants results in increased abundance of Ozone] which results in increased expression of CDCA5 mRNA; [NOTCH3 gene mutant form affects the susceptibility to Ozone] which results in increased expression of CDCA5 mRNAPMID:25658374 PMID:27106289 PMID:34911549
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