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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1560863
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Cdca5
Name: cell division cycle associated 5
Acc ID: CHEBI:29865
Term: benzo[a]pyrene
Definition: An ortho- and peri-fused polycyclic arene consisting of five fused benzene rings.
Chemical ID: MESH:D001564
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Cdca5decreases expressionISOCDCA5 (Homo sapiens)6480464CTDBenzo(a)pyrene results in decreased expression of CDCA5 mRNAPMID:20064835
Cdca5decreases expressionISOCdca5 (Mus musculus)6480464CTDBenzo(a)pyrene results in decreased expression of CDCA5 mRNAPMID:19770486
Cdca5decreases methylationISOCDCA5 (Homo sapiens)6480464CTDBenzo(a)pyrene results in decreased methylation of CDCA5 3' UTRPMID:27901495
Cdca5increases expressionISOCDCA5 (Homo sapiens)6480464CTDBenzo(a)pyrene results in increased expression of CDCA5 mRNAPMID:32234424
Cdca5increases expressionISOCdca5 (Mus musculus)6480464CTDBenzo(a)pyrene results in increased expression of CDCA5 mRNAPMID:20504355 PMID:20713471 PMID:32417428
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