Cdca5 (cell division cycle associated 5) - Rat Genome Database

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Gene: Cdca5 (cell division cycle associated 5) Mus musculus
Analyze
Symbol: Cdca5
Name: cell division cycle associated 5
RGD ID: 1622313
MGI Page MGI
Description: Involved in mitotic sister chromatid cohesion. Localizes to chromatin; cytoplasm; and nucleus. Is expressed in several structures, including alimentary system; brain; genitourinary system; hemolymphoid system; and integumental system. Orthologous to human CDCA5 (cell division cycle associated 5); INTERACTS WITH 1,1-dichloroethene; 1,2-dimethylhydrazine; 17alpha-ethynylestradiol.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: 2610036L13Rik; AL024086; AW536684; C85404; cell division cycle-associated protein 5; sororin; sororin p35
RGD Orthologs
Human
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Related Pseudogenes: Gm14825  
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39196,135,127 - 6,141,803 (+)NCBIGRCm39mm39
GRCm39 Ensembl196,135,013 - 6,141,807 (+)Ensembl
GRCm38196,085,097 - 6,091,773 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl196,084,983 - 6,091,777 (+)EnsemblGRCm38mm10GRCm38
MGSCv37196,085,097 - 6,091,773 (+)NCBIGRCm37mm9NCBIm37
MGSCv36196,085,097 - 6,091,773 (+)NCBImm8
Celera195,957,560 - 5,964,236 (+)NCBICelera
Cytogenetic Map19ANCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
1,1-dichloroethene  (EXP)
1,2-dimethylhydrazine  (EXP)
17alpha-ethynylestradiol  (EXP)
17beta-estradiol  (EXP,ISO)
2,2',4,4',5,5'-hexachlorobiphenyl  (EXP)
2,2',5,5'-tetrachlorobiphenyl  (EXP)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
3,3',4,4',5-pentachlorobiphenyl  (EXP)
3-isobutyl-1-methyl-7H-xanthine  (ISO)
3-methylcholanthrene  (EXP)
5-fluorouracil  (ISO)
acetamide  (ISO)
acrylamide  (ISO)
aflatoxin B1  (EXP,ISO)
arsane  (EXP)
arsenic atom  (EXP)
azathioprine  (ISO)
benzo[a]pyrene  (EXP,ISO)
benzo[a]pyrene diol epoxide I  (ISO)
benzo[b]fluoranthene  (EXP)
beta-naphthoflavone  (EXP)
bis(2-chloroethyl) sulfide  (ISO)
bisphenol A  (ISO)
cadmium atom  (ISO)
calcitriol  (ISO)
carbon nanotube  (EXP)
choline  (EXP)
cisplatin  (ISO)
copper atom  (ISO)
copper(0)  (ISO)
coumestrol  (ISO)
cycloheximide  (ISO)
cyclosporin A  (ISO)
dexamethasone  (ISO)
diazinon  (ISO)
dibenz[a,h]anthracene  (EXP)
dibutyl phthalate  (EXP)
diclofenac  (EXP)
dioxygen  (ISO)
doxorubicin  (ISO)
endosulfan  (ISO)
Enterolactone  (ISO)
folic acid  (EXP)
genistein  (ISO)
indometacin  (ISO)
L-methionine  (EXP)
leflunomide  (ISO)
menadione  (ISO)
methyl methanesulfonate  (ISO)
N-nitrosodiethylamine  (EXP)
nickel atom  (ISO)
nickel dichloride  (ISO)
niclosamide  (ISO)
ozone  (EXP)
palbociclib  (ISO)
paracetamol  (ISO)
PCB138  (EXP)
perfluorooctanoic acid  (ISO)
phenobarbital  (EXP)
phytoestrogen  (ISO)
pirinixic acid  (EXP)
potassium dichromate  (ISO)
propanal  (ISO)
quercetin  (ISO)
resveratrol  (ISO)
silicon dioxide  (EXP)
sodium arsenite  (ISO)
sunitinib  (ISO)
T-2 toxin  (ISO)
tacrolimus hydrate  (EXP)
testosterone  (ISO)
tetrachloromethane  (EXP)
titanium dioxide  (EXP)
trichloroethene  (EXP)
trimellitic anhydride  (EXP)
troglitazone  (ISO)
urethane  (ISO)
valproic acid  (EXP,ISO)
zinc atom  (ISO)
zinc(0)  (ISO)
zoledronic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
chromatin  (IDA)
chromosome  (IEA)
cytoplasm  (IDA)
nucleoplasm  (ISO)
nucleus  (IBA,IDA)

Molecular Function

References

Additional References at PubMed
PMID:7671812   PMID:10349636   PMID:10725249   PMID:10922068   PMID:11042159   PMID:11076861   PMID:11217851   PMID:12466851   PMID:12477932   PMID:14610273   PMID:14681479   PMID:15489334  
PMID:15782199   PMID:15837422   PMID:16141072   PMID:16141073   PMID:16602821   PMID:18799693   PMID:20360068   PMID:21111234   PMID:21267068   PMID:21440680   PMID:21699228   PMID:21873635  
PMID:23901111   PMID:23920377   PMID:24194600   PMID:25956904   PMID:26410627   PMID:26496610   PMID:26903600   PMID:27626380   PMID:27826797   PMID:28050734  


Genomics

Comparative Map Data
Cdca5
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39196,135,127 - 6,141,803 (+)NCBIGRCm39mm39
GRCm39 Ensembl196,135,013 - 6,141,807 (+)Ensembl
GRCm38196,085,097 - 6,091,773 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl196,084,983 - 6,091,777 (+)EnsemblGRCm38mm10GRCm38
MGSCv37196,085,097 - 6,091,773 (+)NCBIGRCm37mm9NCBIm37
MGSCv36196,085,097 - 6,091,773 (+)NCBImm8
Celera195,957,560 - 5,964,236 (+)NCBICelera
Cytogenetic Map19ANCBI
CDCA5
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1165,066,300 - 65,084,164 (-)EnsemblGRCh38hg38GRCh38
GRCh381165,061,009 - 65,084,129 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371164,844,925 - 64,851,512 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361164,601,503 - 64,608,100 (-)NCBINCBI36hg18NCBI36
Build 341164,601,502 - 64,608,100NCBI
Celera1162,171,226 - 62,177,913 (-)NCBI
Cytogenetic Map11q13.1NCBI
HuRef1161,171,560 - 61,178,247 (-)NCBIHuRef
CHM1_11164,728,627 - 64,735,313 (-)NCBICHM1_1
Cdca5
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21203,378,550 - 203,392,027 (+)NCBI
Rnor_6.0 Ensembl1221,448,661 - 221,462,233 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.01221,448,661 - 221,462,235 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01228,384,097 - 228,394,997 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41210,247,351 - 210,247,881 (-)NCBIRGSC3.4rn4RGSC3.4
Celera1200,912,264 - 200,925,714 (+)NCBICelera
Cytogenetic Map1q43NCBI
Cdca5
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_00495542220,114,565 - 20,129,679 (+)NCBIChiLan1.0ChiLan1.0
CDCA5
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11852,115,081 - 52,129,223 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1852,115,203 - 52,120,817 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1850,723,160 - 50,736,970 (+)NCBI
ROS_Cfam_1.01853,156,720 - 53,170,506 (+)NCBI
UMICH_Zoey_3.11852,251,940 - 52,258,937 (+)NCBI
UNSW_CanFamBas_1.01851,825,978 - 51,839,752 (+)NCBI
UU_Cfam_GSD_1.01852,620,789 - 52,634,766 (+)NCBI
Cdca5
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244049477,842,550 - 7,856,508 (+)NCBI
SpeTri2.0NW_0049365994,285,007 - 4,291,875 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CDCA5
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl27,102,982 - 7,113,202 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.127,103,648 - 7,112,772 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.226,235,704 - 6,251,945 (+)NCBISscrofa10.2Sscrofa10.2susScr3
CDCA5
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.119,151,503 - 9,157,412 (+)NCBI
ChlSab1.1 Ensembl19,151,712 - 9,157,456 (+)Ensembl
Vero_WHO_p1.0NW_023666038106,533,173 - 106,538,620 (+)NCBI
Cdca5
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462476721,321,286 - 21,327,780 (+)NCBI

Position Markers
RH127184  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38196,091,454 - 6,091,684UniSTSGRCm38
GRCm38X94,332,416 - 94,332,659UniSTSGRCm38
MGSCv37X91,577,755 - 91,577,998UniSTSGRCm37
MGSCv37196,091,454 - 6,091,684UniSTSGRCm37
Celera195,963,917 - 5,964,147UniSTS
CeleraX81,255,111 - 81,255,354UniSTS
Cytogenetic Map19AUniSTS
Cytogenetic MapXC3UniSTS
Whitehead/MRC_RH190.0UniSTS
AW536684  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38196,091,124 - 6,091,206UniSTSGRCm38
MGSCv37196,091,124 - 6,091,206UniSTSGRCm37
Celera195,963,587 - 5,963,669UniSTS
Cytogenetic Map19AUniSTS
Whitehead/MRC_RH1939.35UniSTS
RH125473  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38196,091,193 - 6,091,570UniSTSGRCm38
MGSCv37196,091,193 - 6,091,570UniSTSGRCm37
Celera195,963,656 - 5,964,033UniSTS
Cytogenetic Map19AUniSTS


QTLs in Region (GRCm38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1300776Lfp3_mlong free running period 3 (mouse)Not determined19120278703Mouse
4142161Drinksac2_mdrink saccharin 2 (mouse)Not determined120645286Mouse
4142302Nstr1_mnerve sheath tumor resistance QTL 1 (mouse)Not determined19122321310Mouse
1301271Datd_mdopamine transporter density (mouse)Not determined19132362870Mouse
4142406Pbctlp1_mperipheral blood cytotoxic T lymphocyte percentage 1 (mouse)Not determined132897810Mouse
1300904Chab5_mcholesterol absorption 5 (mouse)Not determined19167640035676563Mouse
26884385Skwq14_mskull length QTL 14, 16 week (mouse)19320000035900000Mouse
1357819Tgct2_mtesticular germ cell tumor 2 (mouse)Not determined19327855120562299Mouse
1300923Bits4_mbitterness sensitivity 4 (mouse)Not determined19334585237345984Mouse
1301800Faq10_mfluctuating asymmetry QTL 10 (mouse)Not determined19334585237345984Mouse
1300591Pas3_mpulmonary adenoma susceptibility 3 (mouse)Not determined19334585237345984Mouse
1302126Skull26_mskull morphology 26 (mouse)Not determined19334585237345984Mouse
25394536Skmw86_mskeletal muscle weight 86, TA (mouse)1950147898980461Mouse
11039522Tbbr4_mTrypanosoma brucei brucei response 4 (mouse)19533596239336106Mouse

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:804
Count of miRNA genes:429
Interacting mature miRNAs:490
Transcripts:ENSMUST00000025704, ENSMUST00000152528, ENSMUST00000156961
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSMUST00000025704   ⟹   ENSMUSP00000025704
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl196,084,983 - 6,091,777 (+)Ensembl
RefSeq Acc Id: ENSMUST00000152528
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl196,085,827 - 6,091,777 (+)Ensembl
RefSeq Acc Id: ENSMUST00000156961
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl196,085,751 - 6,091,777 (+)Ensembl
RefSeq Acc Id: NM_026410   ⟹   NP_080686
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39196,135,127 - 6,141,803 (+)NCBI
GRCm38196,085,097 - 6,091,773 (+)ENTREZGENE
MGSCv37196,085,097 - 6,091,773 (+)RGD
Celera195,957,560 - 5,964,236 (+)RGD
cM Map19 ENTREZGENE
Sequence:
Reference Sequences
RefSeq Acc Id: NP_080686   ⟸   NM_026410
- UniProtKB: Q9CPY3 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: ENSMUSP00000025704   ⟸   ENSMUST00000025704

Promoters
RGD ID:6829910
Promoter ID:MM_KWN:26148
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day1,   3T3L1_Day4,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   ES_Cell,   Kidney,   Liver,   Lung,   MEF_B4,   MEF_B6,   Spleen
Transcripts:OTTMUST00000042057,   OTTMUST00000071819,   OTTMUST00000071820,   OTTMUST00000071822,   OTTMUST00000071823,   OTTMUST00000071824,   OTTMUST00000071825,   OTTMUST00000071826,   OTTMUST00000071827
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36196,084,656 - 6,085,156 (+)MPROMDB
RGD ID:13678630
Promoter ID:EPDNEW_M23464
Type:initiation region
Name:Cdca5_1
Description:Mus musculus cell division cycle associated 5 , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38196,085,046 - 6,085,106EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1915099 AgrOrtholog
Ensembl Genes ENSMUSG00000024791 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Protein ENSMUSP00000025704 ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000025704 ENTREZGENE, UniProtKB/Swiss-Prot
InterPro Sororin UniProtKB/Swiss-Prot
KEGG Report mmu:67849 UniProtKB/Swiss-Prot
MGD MGI:1915099 ENTREZGENE
NCBI Gene 67849 ENTREZGENE
PANTHER PTHR31092 UniProtKB/Swiss-Prot
Pfam Sororin UniProtKB/Swiss-Prot
PhenoGen Cdca5 PhenoGen
UniProt CDCA5_MOUSE UniProtKB/Swiss-Prot, ENTREZGENE
UniProt Secondary Q78HI6 UniProtKB/Swiss-Prot