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Gene: Bad (BCL2-associated agonist of cell death) Rattus norvegicus
Symbol: Bad
Name: BCL2-associated agonist of cell death
Description: Exhibits 14-3-3 protein binding activity; protein kinase B binding activity; and protein phosphatase 2B binding activity. Involved in several processes, including cellular response to chromate; positive regulation of cell death; and response to steroid hormone. Localizes to cytosol and mitochondrion. Used to study colon cancer; diabetic neuropathy; gastric ulcer; impotence; and middle cerebral artery infarction. Biomarker of several diseases, including acute kidney failure; artery disease (multiple); brain disease (multiple); obesity; and type 2 diabetes mellitus. Human ortholog(s) of this gene implicated in endometrial cancer; lung non-small cell carcinoma; and pancreatic cancer. Orthologous to human BAD (BCL2 associated agonist of cell death); PARTICIPATES IN adenosine signaling pathway; ceramide signaling pathway; endometrial cancer pathway; INTERACTS WITH (+)-alpha-tocopherol; (S)-nicotine; 1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane.
Type: protein-coding
Also known as: Bad_v1; Bad_v2; bcl-2 associated death agonist; bcl-2-binding component 6; bcl-xL/Bcl-2-associated death promoter; bcl2 antagonist of cell death; Bcl2-antagonist of cell death; BCL2-associated agonist of cell death, variant 1; BCL2-associated agonist of cell death, variant 2; bcl2-associated death promoter; MGC72439
Homo sapiens (human) : BAD (BCL2 associated agonist of cell death)  HGNC  Alliance
Mus musculus (house mouse) : Bad (BCL2-associated agonist of cell death)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Bad (BCL2 associated agonist of cell death)
Pan paniscus (bonobo/pygmy chimpanzee) : BAD (BCL2 associated agonist of cell death)
Canis lupus familiaris (dog) : BAD (BCL2 associated agonist of cell death)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Bad (BCL2 associated agonist of cell death)
Sus scrofa (pig) : BAD (BCL2 associated agonist of cell death)
Chlorocebus sabaeus (African green monkey) : BAD (BCL2 associated agonist of cell death)
Heterocephalus glaber (naked mole-rat) : Bad (BCL2 associated agonist of cell death)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.01222,198,516 - 222,207,459 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1222,198,534 - 222,207,453 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01229,189,271 - 229,198,306 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41209,617,373 - 209,626,292 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11209,775,802 - 209,784,722NCBI
Celera1201,667,864 - 201,676,765 (+)NCBICelera
Cytogenetic Map1q43NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Bad
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 620103
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2020-06-09
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.