Itgax (integrin subunit alpha X) - Rat Genome Database

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Gene: Itgax (integrin subunit alpha X) Rattus norvegicus
Analyze
Symbol: Itgax
Name: integrin subunit alpha X
RGD ID: 1561123
Description: Predicted to enable integrin binding activity and receptor tyrosine kinase binding activity. Predicted to be involved in several processes, including integrin-mediated signaling pathway; positive regulation of endothelial tube morphogenesis; and positive regulation of myelination. Predicted to act upstream of or within defense response to virus. Predicted to be located in cell surface. Predicted to be part of integrin alphaX-beta2 complex. Predicted to be active in external side of plasma membrane. Orthologous to human ITGAX (integrin subunit alpha X); PARTICIPATES IN integrin mediated signaling pathway; tuberculosis pathway; INTERACTS WITH 17beta-estradiol; 17beta-estradiol 3-benzoate; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: integrin alpha X; integrin alpha-X; integrin, alpha X; LOC499271; RGD1561123; similar to mFLJ00114 protein
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81192,140,089 - 192,171,151 (+)NCBIGRCr8
mRatBN7.21182,709,653 - 182,740,709 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1182,719,609 - 182,740,698 (+)EnsemblmRatBN7.2 Ensembl
Rnor_6.01199,555,560 - 199,576,948 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1199,555,722 - 199,576,932 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01206,583,608 - 206,604,971 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41187,396,184 - 187,416,273 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1180,365,552 - 180,386,832 (+)NCBICelera
Cytogenetic Map1q37NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
ItgaxRatbranched-chain keto acid dehydrogenase kinase deficiency  ISOITGAX (Homo sapiens)8554872ClinVar Annotator: match by term: Branched-chain keto acid dehydrogenase kinase deficiencyClinVarPMID:25741868
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
ItgaxRatacute promyelocytic leukemia  ISOITGAX (Homo sapiens)11554173CTD Direct Evidence: marker/mechanismCTDPMID:16764927

1 to 20 of 129 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
ItgaxRat1,1-dichloroethene increases expressionISOItgax (Mus musculus)6480464vinylidene chloride results in increased expression of ITGAX mRNACTDPMID:26682919
ItgaxRat1,2-dichloroethane decreases expressionISOItgax (Mus musculus)6480464ethylene dichloride results in decreased expression of ITGAX mRNACTDPMID:28960355
ItgaxRat1,2-dimethylhydrazine affects expressionISOItgax (Mus musculus)64804641 and 2-Dimethylhydrazine affects the expression of ITGAX mRNACTDPMID:22206623
ItgaxRat17beta-estradiol increases expressionISOItgax (Mus musculus)6480464Estradiol results in increased expression of ITGAX proteinCTDPMID:28811679
ItgaxRat17beta-estradiol multiple interactionsEXP 6480464[estradiol 3-benzoate co-treated with [Testosterone co-treated with Estradiol]] results in increased expression of ITGAX mRNACTDPMID:32741896
ItgaxRat17beta-estradiol 3-benzoate multiple interactionsEXP 6480464[estradiol 3-benzoate co-treated with [Testosterone co-treated with Estradiol]] results in increased expression of ITGAX mRNACTDPMID:32741896
ItgaxRat2,3,7,8-tetrachlorodibenzodioxine multiple interactionsISOItgax (Mus musculus)6480464AHR protein affects the reaction [Tetrachlorodibenzodioxin results in decreased expression of ITGAX protein] more ...CTDPMID:20350561 and PMID:21097750
ItgaxRat2,3,7,8-tetrachlorodibenzodioxine affects expressionEXP 6480464Tetrachlorodibenzodioxin affects the expression of ITGAX mRNACTDPMID:34747641
ItgaxRat2,3,7,8-tetrachlorodibenzodioxine affects expressionISOItgax (Mus musculus)6480464Tetrachlorodibenzodioxin affects the expression of ITGAX mRNACTDPMID:26377647
ItgaxRat2,3,7,8-tetrachlorodibenzodioxine decreases expressionISOItgax (Mus musculus)6480464Tetrachlorodibenzodioxin results in decreased expression of ITGAX proteinCTDPMID:17681673 more ...
ItgaxRat2,4-dibromophenyl 2,4,5-tribromophenyl ether affects expressionISOItgax (Mus musculus)64804642 more ...CTDPMID:38648751
ItgaxRat4,4'-sulfonyldiphenol decreases expressionISOITGAX (Homo sapiens)6480464bisphenol S results in decreased expression of ITGAX mRNACTDPMID:33476716
ItgaxRat5-aza-2'-deoxycytidine affects expressionISOITGAX (Homo sapiens)6480464Decitabine affects the expression of ITGAX mRNACTDPMID:23300844
ItgaxRat9-cis-retinoic acid multiple interactionsISOITGAX (Homo sapiens)6480464Dimethyl Sulfoxide promotes the reaction [Alitretinoin results in increased expression of ITGAX protein] and Vitamin D promotes the reaction [Alitretinoin results in increased expression of ITGAX protein]CTDPMID:15964820
ItgaxRatAflatoxin B2 alpha increases methylationISOITGAX (Homo sapiens)6480464aflatoxin B2 results in increased methylation of ITGAX exonCTDPMID:30157460
ItgaxRatall-trans-retinoic acid increases expressionISOITGAX (Homo sapiens)6480464Tretinoin results in increased expression of ITGAX mRNA and Tretinoin results in increased expression of ITGAX proteinCTDPMID:15770638 more ...
ItgaxRatall-trans-retinoic acid multiple interactionsISOITGAX (Homo sapiens)6480464LAT2 protein inhibits the reaction [Tretinoin results in increased expression of ITGAX protein]CTDPMID:32587277
ItgaxRatantirheumatic drug decreases expressionISOITGAX (Homo sapiens)6480464Antirheumatic Agents results in decreased expression of ITGAX mRNACTDPMID:24449571
ItgaxRatarsenite(3-) decreases expressionISOItgax (Mus musculus)6480464arsenite results in decreased expression of ITGAX mRNACTDPMID:18191166
ItgaxRatarsenous acid decreases expressionISOITGAX (Homo sapiens)6480464Arsenic Trioxide results in decreased expression of ITGAX proteinCTDPMID:16174796

1 to 20 of 129 rows

Biological Process
1 to 20 of 25 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
ItgaxRatactivated T cell proliferation NOT|acts_upstream_of_or_withinISOItgax (Mus musculus)1624291MGI:3579560 PMID:15210787RGDPMID:15210787
ItgaxRatcell adhesion involved_inIEAUniProtKB-KW:KW-01301600115GO_REF:0000043UniProtGO_REF:0000043
ItgaxRatcell adhesion involved_inIEAInterPro:IPR0004131600115GO_REF:0000002InterProGO_REF:0000002
ItgaxRatcell adhesion mediated by integrin involved_inIBAFB:FBgn0001250 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
ItgaxRatcell-cell adhesion involved_inIBAMGI:96602 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
ItgaxRatdefense response to virus acts_upstream_of_or_withinISOItgax (Mus musculus)1624291 PMID:17277142RGDPMID:17277142
ItgaxRatdefense response to virus acts_upstream_of_or_withinIEAUniProtKB:Q9QXH4 and ensembl:ENSMUSP000000330531600115GO_REF:0000107EnsemblGO_REF:0000107
ItgaxRatheterotypic cell-cell adhesion involved_inISOITGAX (Homo sapiens)1624291 PMID:20563599RGDPMID:20563599
ItgaxRatheterotypic cell-cell adhesion involved_inIEAUniProtKB:P20702 and ensembl:ENSP000002682961600115GO_REF:0000107EnsemblGO_REF:0000107
ItgaxRatintegrin-mediated signaling pathway involved_inIBAPANTHER:PTN001144284 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
ItgaxRatintegrin-mediated signaling pathway involved_inIEAUniProtKB-KW:KW-04011600115GO_REF:0000043UniProtGO_REF:0000043
ItgaxRatpositive regulation of angiogenesis involved_inISOITGAX (Homo sapiens)1624291 PMID:30873824RGDPMID:30873824
ItgaxRatpositive regulation of angiogenesis involved_inIEAUniProtKB:P20702 and ensembl:ENSP000002682961600115GO_REF:0000107EnsemblGO_REF:0000107
ItgaxRatpositive regulation of cell migration involved_inISOITGAX (Homo sapiens)1624291 PMID:30873824RGDPMID:30873824
ItgaxRatpositive regulation of cell migration involved_inIEAUniProtKB:P20702 and ensembl:ENSP000002682961600115GO_REF:0000107EnsemblGO_REF:0000107
ItgaxRatpositive regulation of cell population proliferation involved_inISOITGAX (Homo sapiens)1624291 PMID:30873824RGDPMID:30873824
ItgaxRatpositive regulation of cell population proliferation involved_inIEAUniProtKB:P20702 and ensembl:ENSP000002682961600115GO_REF:0000107EnsemblGO_REF:0000107
ItgaxRatpositive regulation of endothelial tube morphogenesis involved_inISOITGAX (Homo sapiens)1624291 PMID:30873824RGDPMID:30873824
ItgaxRatpositive regulation of endothelial tube morphogenesis involved_inIEAUniProtKB:P20702 and ensembl:ENSP000002682961600115GO_REF:0000107EnsemblGO_REF:0000107
ItgaxRatpositive regulation of gene expression involved_inISOITGAX (Homo sapiens)1624291 PMID:30873824RGDPMID:30873824
1 to 20 of 25 rows

Cellular Component
1 to 11 of 11 rows

  
Object Symbol
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Evidence
With
Reference
Notes
Source
Original Reference(s)
ItgaxRatcell surface located_inISOITGAX (Homo sapiens)1624291 PMID:19234460RGDPMID:19234460
ItgaxRatcell surface located_inIEAUniProtKB:P20702 and ensembl:ENSP000002682961600115GO_REF:0000107EnsemblGO_REF:0000107
ItgaxRatexternal side of plasma membrane is_active_inIBAMGI:1298377 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
ItgaxRatexternal side of plasma membrane located_inIEAUniProtKB:Q9QXH4 and ensembl:ENSMUSP000000330531600115GO_REF:0000107EnsemblGO_REF:0000107
ItgaxRatexternal side of plasma membrane located_inISOItgax (Mus musculus)1624291 PMID:10648399 more ...RGDPMID:10648399 more ...
ItgaxRatintegrin alphaX-beta2 complex part_ofISOITGAX (Homo sapiens)1624291 PMID:20033057RGDPMID:20033057
ItgaxRatintegrin alphaX-beta2 complex part_ofIEAUniProtKB:P20702 and ensembl:ENSP000002682961600115GO_REF:0000107EnsemblGO_REF:0000107
ItgaxRatintegrin complex part_ofIBAFB:FBgn0001250 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
ItgaxRatintegrin complex part_ofIEAInterPro:IPR0004131600115GO_REF:0000002InterProGO_REF:0000002
ItgaxRatmembrane located_inIEAUniProtKB-KW:KW-04721600115GO_REF:0000043UniProtGO_REF:0000043
ItgaxRatmembrane located_inIEAUniProtKB-SubCell:SL-01621600115GO_REF:0000044UniProtGO_REF:0000044
1 to 11 of 11 rows

Molecular Function

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
ItgaxRatintegrin binding enablesIBAMGI:104756 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
ItgaxRatmetal ion binding enablesIEAUniProtKB-KW:KW-04791600115GO_REF:0000043UniProtGO_REF:0000043
ItgaxRatprotein binding enablesISOITGAX (Homo sapiens)1624291UniProtKB:P05107 more ...RGDPMID:17726152 more ...
ItgaxRatreceptor tyrosine kinase binding enablesISOITGAX (Homo sapiens)1624291UniProtKB:P35968 and PMID:30873824RGDPMID:30873824
ItgaxRatreceptor tyrosine kinase binding enablesIEAUniProtKB:P20702 and ensembl:ENSP000002682961600115GO_REF:0000107EnsemblGO_REF:0000107

RGD Manual Annotations


  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
ItgaxRatintegrin mediated signaling pathway   ISOITGAX (Homo sapiens)5135538 RGD 

Imported Annotations - KEGG (archival)

Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
ItgaxRattuberculosis pathway  IEA 6907045 KEGGrno:05152

#
Reference Title
Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
3. GOA pipeline RGD automated data pipeline
4. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
6. The integrins. Takada Y, etal., Genome Biol. 2007;8(5):215.
PMID:1385153   PMID:10648399   PMID:12801066   PMID:14609575   PMID:14643301   PMID:14990792   PMID:15210787   PMID:17277142   PMID:18984740   PMID:19234460   PMID:19723499   PMID:19946888  
PMID:20563599   PMID:23981064   PMID:24270810   PMID:28963396   PMID:30873824  



Itgax
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81192,140,089 - 192,171,151 (+)NCBIGRCr8
mRatBN7.21182,709,653 - 182,740,709 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1182,719,609 - 182,740,698 (+)EnsemblmRatBN7.2 Ensembl
Rnor_6.01199,555,560 - 199,576,948 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1199,555,722 - 199,576,932 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01206,583,608 - 206,604,971 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41187,396,184 - 187,416,273 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1180,365,552 - 180,386,832 (+)NCBICelera
Cytogenetic Map1q37NCBI
ITGAX
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381631,355,176 - 31,382,999 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1631,355,134 - 31,382,999 (+)EnsemblGRCh38hg38GRCh38
GRCh371631,366,497 - 31,394,320 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361631,274,010 - 31,301,819 (+)NCBINCBI36Build 36hg18NCBI36
Build 341631,274,009 - 31,301,819NCBI
Cytogenetic Map16p11.2NCBI
HuRef1628,926,765 - 28,954,574 (+)NCBIHuRef
CHM1_11632,684,617 - 32,713,005 (+)NCBICHM1_1
T2T-CHM13v2.01631,742,566 - 31,770,400 (+)NCBIT2T-CHM13v2.0
Itgax
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm397127,728,697 - 127,749,829 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl7127,728,719 - 127,749,829 (+)EnsemblGRCm39 Ensembl
GRCm387128,129,526 - 128,150,657 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl7128,129,547 - 128,150,657 (+)EnsemblGRCm38mm10GRCm38
MGSCv377135,273,082 - 135,294,171 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv367127,920,716 - 127,941,805 (+)NCBIMGSCv36mm8
Celera7127,963,226 - 127,984,316 (+)NCBICelera
Cytogenetic Map7F3NCBI
cM Map769.98NCBI
Itgax
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_0049554938,196,593 - 8,220,296 (+)NCBIChiLan1.0ChiLan1.0
ITGAX
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21834,562,273 - 34,592,485 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11639,363,701 - 39,393,919 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01623,574,807 - 23,612,638 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11631,724,539 - 31,754,603 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1631,724,113 - 31,797,249 (+)Ensemblpanpan1.1panPan2
ITGAX
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1616,898,143 - 16,927,270 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl616,808,971 - 16,996,286 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha618,487,797 - 18,499,807 (-)NCBIDog10K_Boxer_Tasha
Dog10K_Boxer_Tasha622,643,925 - 22,660,443 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0617,023,380 - 17,052,559 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl616,933,693 - 17,052,528 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1616,826,486 - 16,855,639 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0616,745,644 - 16,774,812 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0617,057,566 - 17,086,388 (-)NCBIUU_Cfam_GSD_1.0
Itgax
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024409344125,593,065 - 125,612,720 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365438,424,672 - 8,442,850 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365438,424,095 - 8,442,850 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ITGAX
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1317,178,725 - 17,201,388 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2317,424,298 - 17,426,519 (+)NCBISscrofa10.2Sscrofa10.2susScr3
ITGAX
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1528,058,172 - 28,087,253 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl528,058,456 - 28,086,838 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660681,354,348 - 1,384,497 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Itgax
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462478214,380,399 - 14,395,916 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462478214,380,234 - 14,397,552 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

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Variants in Itgax
424 total Variants

Predicted Target Of
Summary Value
Count of predictions:101
Count of miRNA genes:84
Interacting mature miRNAs:88
Transcripts:ENSRNOT00000054983
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


1 to 10 of 80 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
1578778Pur4Proteinuria QTL 43.30.003urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)1150700247252085048Rat
1354646Kidm18Kidney mass QTL 185.7kidney mass (VT:0002707)calculated kidney weight (CMO:0000160)1151162512256448636Rat
1578780Cm52Cardiac mass QTL 523.30.0001heart mass (VT:0007028)heart wet weight (CMO:0000069)181591954219808434Rat
1354652Kidm20Kidney mass QTL 204.3kidney mass (VT:0002707)calculated kidney weight (CMO:0000160)1177227632256448636Rat
2302378Insul11Insulin level QTL 113.25blood insulin amount (VT:0001560)serum insulin level (CMO:0000358)1144267353251128347Rat
1354653Despr9Despair related QTL 90.00019locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)1167909849212909849Rat
2293673Bss27Bone structure and strength QTL 2718.630.0001femur morphology trait (VT:0000559)femur midshaft cortical cross-sectional area (CMO:0001663)1171629477216629477Rat
2293677Bss41Bone structure and strength QTL 419.380.0001lumbar vertebra size trait (VT:0010518)lumbar vertebra cross-sectional area (CMO:0001689)1171629477216629477Rat
1302787Stl25Serum triglyceride level QTL 252.70.0073blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)1180359209210702199Rat
70160Bw18Body weight QTL 185.7body mass (VT:0001259)body weight (CMO:0000012)1144267353196383668Rat

1 to 10 of 80 rows



alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 102 91 90 59 25 59 6 218 97 82 45 60 31



Ensembl Acc Id: ENSRNOT00000054983   ⟹   ENSRNOP00000051866
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1182,719,609 - 182,740,698 (+)Ensembl
Rnor_6.0 Ensembl1199,555,722 - 199,576,932 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000099518   ⟹   ENSRNOP00000083288
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1182,719,781 - 182,740,698 (+)Ensembl
RefSeq Acc Id: NM_001419757   ⟹   NP_001406686
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81192,150,049 - 192,171,151 (+)NCBI
mRatBN7.21182,719,607 - 182,740,709 (+)NCBI
RefSeq Acc Id: XM_039101230   ⟹   XP_038957158
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81192,140,089 - 192,171,151 (+)NCBI
mRatBN7.21182,709,653 - 182,740,709 (+)NCBI
RefSeq Acc Id: XM_039101231   ⟹   XP_038957159
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81192,153,645 - 192,171,151 (+)NCBI
mRatBN7.21182,723,203 - 182,740,709 (+)NCBI
RefSeq Acc Id: XM_039101233   ⟹   XP_038957161
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81192,140,089 - 192,154,230 (+)NCBI
mRatBN7.21182,709,653 - 182,724,685 (+)NCBI
RefSeq Acc Id: XM_063271412   ⟹   XP_063127482
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81192,155,466 - 192,171,151 (+)NCBI
RefSeq Acc Id: XR_005499481
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81192,140,089 - 192,155,425 (+)NCBI
mRatBN7.21182,709,653 - 182,724,981 (+)NCBI
1 to 10 of 10 rows
Protein RefSeqs NP_001406686 (Get FASTA)   NCBI Sequence Viewer  
  XP_038957158 (Get FASTA)   NCBI Sequence Viewer  
  XP_038957159 (Get FASTA)   NCBI Sequence Viewer  
  XP_038957161 (Get FASTA)   NCBI Sequence Viewer  
  XP_063127482 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EDM17197 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000051866
  ENSRNOP00000051866.4
  ENSRNOP00000083288
  ENSRNOP00000083288.1
1 to 10 of 10 rows
Ensembl Acc Id: ENSRNOP00000051866   ⟸   ENSRNOT00000054983
RefSeq Acc Id: XP_038957158   ⟸   XM_039101230
- Peptide Label: isoform X1
- UniProtKB: A6I9Y3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038957161   ⟸   XM_039101233
- Peptide Label: isoform X4
RefSeq Acc Id: XP_038957159   ⟸   XM_039101231
- Peptide Label: isoform X2
Ensembl Acc Id: ENSRNOP00000083288   ⟸   ENSRNOT00000099518
VWFA

Name Modeler Protein Id AA Range Protein Structure
AF-D3ZWZ1-F1-model_v2 AlphaFold D3ZWZ1 1-1182 view protein structure


eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen



1 to 40 of 47 rows
Database
Acc Id
Source(s)
BioCyc Gene G2FUF-57312 BioCyc
Ensembl Genes ENSRNOG00000036703 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000054983 ENTREZGENE
  ENSRNOT00000054983.5 UniProtKB/TrEMBL
  ENSRNOT00000099518 ENTREZGENE
  ENSRNOT00000099518.1 UniProtKB/TrEMBL
Gene3D-CATH 2.130.10.130 UniProtKB/TrEMBL
  3.40.50.410 UniProtKB/TrEMBL
  Bicelle-embedded integrin alpha(iib) transmembrane segment UniProtKB/TrEMBL
  Integrin domains. Chain A, domain 2 UniProtKB/TrEMBL
  ntegrin, alpha v. Chain A, domain 3 UniProtKB/TrEMBL
  ntegrin, alpha v. Chain A, domain 4 UniProtKB/TrEMBL
InterPro FG-GAP UniProtKB/TrEMBL
  Int_alpha_beta-p UniProtKB/TrEMBL
  Integrin_alpha UniProtKB/TrEMBL
  Integrin_alpha-2 UniProtKB/TrEMBL
  Integrin_alpha_C_CS UniProtKB/TrEMBL
  Integrin_alpha_Ig-like_2 UniProtKB/TrEMBL
  Integrin_alpha_N UniProtKB/TrEMBL
  Integrin_dom UniProtKB/TrEMBL
  ITGAX-like_Ig_3 UniProtKB/TrEMBL
  VWF_A UniProtKB/TrEMBL
  vWFA_dom_sf UniProtKB/TrEMBL
NCBI Gene 499271 ENTREZGENE
PANTHER INTEGRIN ALPHA UniProtKB/TrEMBL
  INTEGRIN ALPHA-X UniProtKB/TrEMBL
Pfam FG-GAP UniProtKB/TrEMBL
  Integrin_A_Ig_2 UniProtKB/TrEMBL
  Integrin_alpha UniProtKB/TrEMBL
  Integrin_alpha2 UniProtKB/TrEMBL
  ITGAX-like_Ig_3 UniProtKB/TrEMBL
  VWA UniProtKB/TrEMBL
PhenoGen Itgax PhenoGen
PRINTS INTEGRINA UniProtKB/TrEMBL
  VWFADOMAIN UniProtKB/TrEMBL
PROSITE FG_GAP UniProtKB/TrEMBL
  INTEGRIN_ALPHA UniProtKB/TrEMBL
  VWFA UniProtKB/TrEMBL
RatGTEx ENSRNOG00000036703 RatGTEx
SMART Int_alpha UniProtKB/TrEMBL
1 to 40 of 47 rows


Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2015-12-23 Itgax  integrin subunit alpha X  Itgax  integrin, alpha X  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2009-12-15 Itgax  integrin, alpha X  Itgax  integrin alpha X  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-02-28 Itgax  integrin alpha X  RGD1561123_predicted  similar to mFLJ00114 protein (predicted)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-03-07 RGD1561123_predicted  similar to mFLJ00114 protein (predicted)  LOC499271  similar to mFLJ00114 protein  Symbol and Name status set to approved 1299863 APPROVED
2006-02-09 LOC499271  similar to mFLJ00114 protein      Symbol and Name status set to provisional 70820 PROVISIONAL