Imported Disease Annotations - ClinVarTerm | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | familial temporal lobe epilepsy 8 | | ISO | RGD:737532 | 8554872 | ClinVar Annotator: match by term: Familial temporal lobe epilepsy 8 | ClinVar | PMID:28492532 | intellectual disability | | ISO | RGD:737532 | 8554872 | ClinVar Annotator: match by term: Intellectual disability | ClinVar | | | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Gene Ontology Annotations Click to see Annotation Detail View
Biological Process
Cellular Component
Molecular Function
Disease Annotations
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Gene-Chemical Interaction Annotations
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Gene Ontology Annotations
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Biological Process
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Cellular Component
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Molecular Function
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References
References - curated
| # | Reference Title | Reference Citation |
| 1. | Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. | Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27. |
| 2. | Subtraction cloning of H-rev107, a gene specifically expressed in H-ras resistant fibroblasts. | Hajnal A, etal., Oncogene 1994 Feb;9(2):479-90. |
| 3. | High-density rat radiation hybrid maps containing over 24,000 SSLPs, genes, and ESTs provide a direct link to the rat genome sequence. | Kwitek AE, etal., Genome Res. 2004 Apr;14(4):750-7 |
| 4. | Tyrosines1234-1235 are critical for activation of the tyrosine kinase encoded by the MET proto-oncogene (HGF receptor). | Longati P, etal., Oncogene 1994 Jan;9(1):49-57. |
| 5. | Electronic Transfer of LocusLink and RefSeq Data | NCBI rat LocusLink and RefSeq merged data July 26, 2002 |
| 6. | GOA pipeline | RGD automated data pipeline |
| 7. | Data Import for Chemical-Gene Interactions | RGD automated import pipeline for gene-chemical interactions |
| 8. | Comprehensive gene review and curation | RGD comprehensive gene curation |
| 9. | Growth-inhibitory activity and downregulation of the class II tumor-suppressor gene H-rev107 in tumor cell lines and experimental tumors. | Sers C, etal., J Cell Biol. 1997 Feb 24;136(4):935-44. |
| 10. | hH-Rev107, a class II tumor suppressor gene, is expressed by post-meiotic testicular germ cells and CIS cells but not by human testicular germ cell tumors. | Siegrist S, etal., Oncogene. 2001 Aug 23;20(37):5155-63. |
| 11. | The tumor suppressor gene H-Rev107 functions as a novel Ca2+-independent cytosolic phospholipase A1/2 of the thiol hydrolase type. | Uyama T, etal., J Lipid Res. 2009 Apr;50(4):685-93. doi: 10.1194/jlr.M800453-JLR200. Epub 2008 Dec 1. |
Additional References at PubMed
| PMID:18614531 | PMID:19136964 | PMID:20100577 | PMID:22134920 | PMID:22825852 | PMID:23012479 |
Genomics
Candidate Gene Status
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Plaat3 is a candidate Gene for QTL Hcar4 |
Comparative Map Data
| Plaat3 (Rattus norvegicus - Norway rat) |
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| PLAAT3 (Homo sapiens - human) |
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| Plaat3 (Mus musculus - house mouse) |
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| PLAAT3 (Pan paniscus - bonobo/pygmy chimpanzee) |
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| PLAAT3 (Canis lupus familiaris - dog) |
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| Plaat3 (Ictidomys tridecemlineatus - thirteen-lined ground squirrel) |
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| PLAAT3 (Sus scrofa - pig) |
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| PLAAT3 (Chlorocebus sabaeus - green monkey) |
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Position Markers
| RH142176 |
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QTLs in Region (mRatBN7.2)
| The following QTLs overlap with this region. | | Full Report | | CSV | | TAB | | Printer | | Gviewer |