Plaat3 (phospholipase A and acyltransferase 3) - Rat Genome Database

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Gene: Plaat3 (phospholipase A and acyltransferase 3) Rattus norvegicus
Analyze
Symbol: Plaat3
Name: phospholipase A and acyltransferase 3
RGD ID: 2829
Description: Enables phospholipase A1 activity and phospholipase A2 activity. Involved in negative regulation of cell cycle. Predicted to be located in several cellular components, including nuclear envelope; perinuclear region of cytoplasm; and peroxisome. Predicted to be active in cytoplasm. Orthologous to human PLAAT3 (phospholipase A and acyltransferase 3); INTERACTS WITH (+)-schisandrin B; 2,2',4,4'-Tetrabromodiphenyl ether; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: group XVI phospholipase A1/A2; group XVI phospholipase A2; H-rev 107 protein; H-rev 107 protein homolog; HRAS like suppressor; HRAS like suppressor 3; HRAS-like suppressor 3; Hras-revertant gene 107; Hras-revertant gene 107 (expression down-regulated in HRAS-transformed rat 208F fibroblasts); Hrasls3; Hrev107; HRSL3; LRAT-like protein-3; phospholipase A2, group XVI; Pla2g16; RLP-3
RGD Orthologs
Human
Mouse
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Orthologs
More Info more info ...
Candidate Gene For: Hcar4
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81214,211,755 - 214,245,551 (+)NCBIGRCr8
mRatBN7.21204,782,608 - 204,816,397 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1204,782,729 - 204,817,667 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1213,132,708 - 213,166,583 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01220,227,923 - 220,261,595 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01212,918,978 - 212,952,652 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01222,844,238 - 222,877,180 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1222,844,144 - 222,877,193 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01229,831,484 - 229,864,268 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41210,281,109 - 210,315,280 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11784,429,015 - 84,429,766 (+)NCBI
Celera1202,309,606 - 202,343,352 (+)NCBICelera
RH 3.4 Map11522.4RGD
Cytogenetic Map1q43NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model



  
Object Symbol
Species
Term
Qualifier
Evidence
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Reference
Notes
Source
Original Reference(s)
Plaat3RatBreast Neoplasms  ISOPlaat3 (Mus musculus)2290001 RGD 
Plaat3Ratseminoma  ISOPLAAT3 (Homo sapiens)2290002 RGD 
Plaat3RatTesticular Neoplasms  ISOPLAAT3 (Homo sapiens)2290002 RGD 
Object Symbol
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Term
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Reference
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Original Reference(s)
Plaat3RatFamilial Partial Lipodystrophy Type 9  ISOPLAAT3 (Homo sapiens)8554872ClinVar Annotator: match by term: Lipodystrophy more ...ClinVar 
Plaat3Ratintellectual disability  ISOPLAAT3 (Homo sapiens)8554872ClinVar Annotator: match by term: Intellectual disabilityClinVar 
Plaat3Ratleukocyte adhesion deficiency 3  ISOPLAAT3 (Homo sapiens)8554872ClinVar Annotator: match by term: Leukocyte adhesion deficiency 3ClinVarPMID:28492532
Object Symbol
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Original Reference(s)
Plaat3RatFamilial Partial Lipodystrophy Type 9  ISOPLAAT3 (Homo sapiens)7240710 OMIM 

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Object Symbol
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Original Reference(s)
Plaat3Rat(+)-catechin multiple interactionsISOPLAAT3 (Homo sapiens)6480464[Catechin co-treated with Grape Seed Proanthocyanidins] results in decreased expression of PLAAT3 mRNACTDPMID:24763279
Plaat3Rat(+)-schisandrin B multiple interactionsEXP 6480464schizandrin B inhibits the reaction [Carbon Tetrachloride results in decreased expression of PLAAT3 mRNA]CTDPMID:31150632
Plaat3Rat(R)-lipoic acid decreases expressionISOPlaat3 (Mus musculus)6480464Thioctic Acid results in decreased expression of PLAAT3 mRNACTDPMID:22941773
Plaat3Rat(R)-lipoic acid decreases activityISOPlaat3 (Mus musculus)6480464Thioctic Acid results in decreased activity of PLAAT3 proteinCTDPMID:22941773
Plaat3Rat17beta-estradiol multiple interactionsISOPLAAT3 (Homo sapiens)6480464[Estradiol co-treated with TGFB1 protein] results in decreased expression of PLAAT3 mRNACTDPMID:30165855
Plaat3Rat2,2',4,4'-Tetrabromodiphenyl ether decreases expressionEXP 64804642 more ...CTDPMID:31826744
Plaat3Rat2,3,7,8-tetrachlorodibenzodioxine increases expressionISOPLAAT3 (Homo sapiens)6480464Tetrachlorodibenzodioxin results in increased expression of PLAAT3 mRNACTDPMID:20106945 more ...
Plaat3Rat2,3,7,8-tetrachlorodibenzodioxine increases expressionEXP 6480464Tetrachlorodibenzodioxin results in increased expression of PLAAT3 mRNACTDPMID:34747641
Plaat3Rat2,3,7,8-tetrachlorodibenzodioxine decreases expressionEXP 6480464Tetrachlorodibenzodioxin results in decreased expression of PLAAT3 mRNACTDPMID:21215274 and PMID:32109520
Plaat3Rat2,3,7,8-tetrachlorodibenzodioxine decreases expressionISOPlaat3 (Mus musculus)6480464Tetrachlorodibenzodioxin results in decreased expression of PLAAT3 mRNACTDPMID:21354282 and PMID:33956508
Plaat3Rat2,4-dinitrotoluene affects expressionEXP 64804642 and 4-dinitrotoluene affects the expression of PLAAT3 mRNACTDPMID:21346803
Plaat3Rat3,3',5,5'-tetrabromobisphenol A decreases expressionEXP 6480464tetrabromobisphenol A results in decreased expression of PLAAT3 mRNACTDPMID:27914987
Plaat3Rat3,4-methylenedioxymethamphetamine decreases expressionISOPlaat3 (Mus musculus)6480464N-Methyl-3 and 4-methylenedioxyamphetamine results in decreased expression of PLAAT3 mRNACTDPMID:26251327
Plaat3Rat3-chloropropane-1,2-diol increases expressionEXP 6480464alpha-Chlorohydrin results in increased expression of PLAAT3 mRNACTDPMID:28522335
Plaat3Rat3-isobutyl-1-methyl-7H-xanthine multiple interactionsISOPLAAT3 (Homo sapiens)6480464[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in increased expression of PLAAT3 mRNA and [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin] results in increased expression of PLAAT3 mRNACTDPMID:28628672
Plaat3Rat4-amino-2,6-dinitrotoluene affects expressionEXP 64804644-amino-2 and 6-dinitrotoluene affects the expression of PLAAT3 mRNACTDPMID:21346803
Plaat3Rat5-aza-2'-deoxycytidine affects expressionISOPLAAT3 (Homo sapiens)6480464Decitabine affects the expression of PLAAT3 mRNACTDPMID:23300844
Plaat3Rat6-propyl-2-thiouracil decreases expressionEXP 6480464Propylthiouracil results in decreased expression of PLAAT3 mRNACTDPMID:24780913
Plaat3Ratacetamide increases expressionEXP 6480464acetamide results in increased expression of PLAAT3 mRNACTDPMID:31881176
Plaat3Rataflatoxin B1 increases expressionEXP 6480464Aflatoxin B1 results in increased expression of PLAAT3 mRNACTDPMID:33354967

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Biological Process
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Original Reference(s)
Plaat3Ratether lipid metabolic process involved_inISSUniProtKB:Q8R3U11600115GO_REF:0000024UniProtGO_REF:0000024
Plaat3Ratether lipid metabolic process involved_inISOPlaat3 (Mus musculus)1624291 PMID:22134920RGDPMID:22134920
Plaat3Ratlens fiber cell differentiation involved_inISSUniProtKB:Q8R3U11600115GO_REF:0000024UniProtGO_REF:0000024
Plaat3Ratlens fiber cell differentiation involved_inISOPlaat3 (Mus musculus)1624291 PMID:33854238RGDPMID:33854238
Plaat3Ratlipid catabolic process involved_inISSUniProtKB:Q8R3U11600115GO_REF:0000024UniProtGO_REF:0000024
Plaat3Ratlipid catabolic process involved_inIEAUniProtKB-KW:KW-04421600115GO_REF:0000043UniProtGO_REF:0000043
Plaat3Ratlipid catabolic process involved_inISOPlaat3 (Mus musculus)1624291 PMID:19136964RGDPMID:19136964
Plaat3Ratlipid metabolic process involved_inIEAUniProtKB-KW:KW-04431600115GO_REF:0000043UniProtGO_REF:0000043
Plaat3Ratmembrane disassembly involved_inISSUniProtKB:Q8R3U11600115GO_REF:0000024UniProtGO_REF:0000024
Plaat3Ratmembrane disassembly involved_inISOPlaat3 (Mus musculus)1624291 PMID:33854238RGDPMID:33854238
Plaat3RatN-acylphosphatidylethanolamine metabolic process involved_inISSUniProtKB:P538161600115GO_REF:0000024UniProtGO_REF:0000024
Plaat3RatN-acylphosphatidylethanolamine metabolic process involved_inIBAMGI:1913977 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Plaat3RatN-acylphosphatidylethanolamine metabolic process involved_inIEAUniProtKB:P53816 and ensembl:ENSP000003891241600115GO_REF:0000107EnsemblGO_REF:0000107
Plaat3RatN-acylphosphatidylethanolamine metabolic process involved_inISOPLAAT3 (Homo sapiens)1624291 PMID:22825852RGDPMID:22825852
Plaat3Ratnegative regulation of cell cycle  IMP 708597 RGD 
Plaat3Ratorganelle disassembly involved_inISSUniProtKB:Q8R3U11600115GO_REF:0000024UniProtGO_REF:0000024
Plaat3Ratorganelle disassembly involved_inISOPlaat3 (Mus musculus)1624291 PMID:33854238RGDPMID:33854238
Plaat3Ratperoxisome organization involved_inISSUniProtKB:Q8R3U11600115GO_REF:0000024UniProtGO_REF:0000024
Plaat3Ratperoxisome organization involved_inISOPlaat3 (Mus musculus)1624291 PMID:22134920RGDPMID:22134920
Plaat3Ratphospholipid biosynthetic process involved_inISOPlaat3 (Mus musculus)1624291 PMID:18614531RGDPMID:18614531
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Cellular Component
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Original Reference(s)
Plaat3Ratcytoplasm is_active_inIBAMGI:1351473 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Plaat3Ratcytoplasm located_inIEAUniProtKB-SubCell:SL-00861600115GO_REF:0000044UniProtGO_REF:0000044
Plaat3Ratcytoplasm located_inIEAUniProtKB-KW:KW-09631600115GO_REF:0000043UniProtGO_REF:0000043
Plaat3Ratcytosol located_inISOPlaat3 (Mus musculus)1624291 PMID:33854238RGDPMID:33854238
Plaat3Ratcytosol located_inIEAUniProtKB-SubCell:SL-00911600115GO_REF:0000044UniProtGO_REF:0000044
Plaat3Ratcytosol located_inISSUniProtKB:Q8R3U11600115GO_REF:0000024UniProtGO_REF:0000024
Plaat3Ratendoplasmic reticulum located_inIEAUniProtKB-KW:KW-02561600115GO_REF:0000043UniProtGO_REF:0000043
Plaat3Ratendoplasmic reticulum located_inISOPlaat3 (Mus musculus)1624291 PMID:18614531 and PMID:33854238RGDPMID:18614531 and PMID:33854238
Plaat3Ratendoplasmic reticulum located_inISSUniProtKB:Q8R3U11600115GO_REF:0000024UniProtGO_REF:0000024
Plaat3Ratendoplasmic reticulum membrane located_inIEAUniProtKB-SubCell:SL-00971600115GO_REF:0000044UniProtGO_REF:0000044
Plaat3Ratlysosomal membrane located_inIEAUniProtKB-SubCell:SL-01571600115GO_REF:0000044UniProtGO_REF:0000044
Plaat3Ratlysosome located_inIEAUniProtKB-KW:KW-04581600115GO_REF:0000043UniProtGO_REF:0000043
Plaat3Ratlysosome located_inISOPlaat3 (Mus musculus)1624291 PMID:33854238RGDPMID:33854238
Plaat3Ratlysosome located_inISSUniProtKB:Q8R3U11600115GO_REF:0000024UniProtGO_REF:0000024
Plaat3Ratmembrane located_inIEAUniProtKB-KW:KW-04721600115GO_REF:0000043UniProtGO_REF:0000043
Plaat3Ratmitochondrial membrane located_inIEAUniProtKB-SubCell:SL-01711600115GO_REF:0000044UniProtGO_REF:0000044
Plaat3Ratmitochondrion located_inISSUniProtKB:Q8R3U11600115GO_REF:0000024UniProtGO_REF:0000024
Plaat3Ratmitochondrion located_inIEAUniProtKB-KW:KW-04961600115GO_REF:0000043UniProtGO_REF:0000043
Plaat3Ratmitochondrion located_inISOPlaat3 (Mus musculus)1624291 PMID:33854238RGDPMID:33854238
Plaat3Ratnuclear envelope located_inISSUniProtKB:Q8R3U11600115GO_REF:0000024UniProtGO_REF:0000024
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Molecular Function
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Original Reference(s)
Plaat3Ratacyltransferase activity NOT|enablesISOPlaat3 (Mus musculus)1624291 PMID:18614531RGDPMID:18614531
Plaat3Rathydrolase activity enablesIEAUniProtKB-KW:KW-03781600115GO_REF:0000043UniProtGO_REF:0000043
Plaat3Ratlipid binding enablesISOPLAAT3 (Homo sapiens)1624291 PMID:22605381RGDPMID:22605381
Plaat3RatN-acyltransferase activity enablesISSUniProtKB:P538161600115GO_REF:0000024UniProtGO_REF:0000024
Plaat3RatN-acyltransferase activity enablesIBAMGI:1913977 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Plaat3RatN-acyltransferase activity enablesIEAUniProtKB:P53816 and ensembl:ENSP000003891241600115GO_REF:0000107EnsemblGO_REF:0000107
Plaat3RatN-acyltransferase activity enablesISOPLAAT3 (Homo sapiens)1624291 PMID:22825852RGDPMID:22825852
Plaat3Ratphospholipase A1 activity enablesISOPlaat3 (Mus musculus)1624291 PMID:19047760 and PMID:22134920RGDPMID:19047760 and PMID:22134920
Plaat3Ratphospholipase A1 activity enablesIEARHEA:186891600115GO_REF:0000116RHEAGO_REF:0000116
Plaat3Ratphospholipase A1 activity enablesIEAEC:3.1.1.321600115GO_REF:0000003UniProtGO_REF:0000003
Plaat3Ratphospholipase A1 activity enablesIBAMGI:2179715 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Plaat3Ratphospholipase A1 activity enablesIEAUniProtKB:P53816 and ensembl:ENSP000003891241600115GO_REF:0000107EnsemblGO_REF:0000107
Plaat3Ratphospholipase A1 activity enablesISOPLAAT3 (Homo sapiens)1624291 PMID:19047760 and PMID:22825852RGDPMID:19047760 and PMID:22825852
Plaat3Ratphospholipase A1 activity enablesIDA 12790655PMID:19047760UniProt 
Plaat3Ratphospholipase A2 activity enablesISOPLAAT3 (Homo sapiens)1624291 PMID:19047760 more ...RGDPMID:19047760 more ...
Plaat3Ratphospholipase A2 activity enablesIEAEC:3.1.1.41600115GO_REF:0000003UniProtGO_REF:0000003
Plaat3Ratphospholipase A2 activity enablesISOPlaat3 (Mus musculus)1624291 PMID:18614531 more ...RGDPMID:18614531 more ...
Plaat3Ratphospholipase A2 activity enablesIBAMGI:2179715 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Plaat3Ratphospholipase A2 activity enablesIEARHEA:158011600115GO_REF:0000116RHEAGO_REF:0000116
Plaat3Ratphospholipase A2 activity enablesIEAUniProtKB:P53816 and ensembl:ENSP000003891241600115GO_REF:0000107EnsemblGO_REF:0000107
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#
Reference Title
Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Subtraction cloning of H-rev107, a gene specifically expressed in H-ras resistant fibroblasts. Hajnal A, etal., Oncogene 1994 Feb;9(2):479-90.
3. High-density rat radiation hybrid maps containing over 24,000 SSLPs, genes, and ESTs provide a direct link to the rat genome sequence. Kwitek AE, etal., Genome Res. 2004 Apr;14(4):750-7
4. Tyrosines1234-1235 are critical for activation of the tyrosine kinase encoded by the MET proto-oncogene (HGF receptor). Longati P, etal., Oncogene 1994 Jan;9(1):49-57.
5. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
6. GOA pipeline RGD automated data pipeline
7. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
8. Comprehensive gene review and curation RGD comprehensive gene curation
9. Growth-inhibitory activity and downregulation of the class II tumor-suppressor gene H-rev107 in tumor cell lines and experimental tumors. Sers C, etal., J Cell Biol. 1997 Feb 24;136(4):935-44.
10. hH-Rev107, a class II tumor suppressor gene, is expressed by post-meiotic testicular germ cells and CIS cells but not by human testicular germ cell tumors. Siegrist S, etal., Oncogene. 2001 Aug 23;20(37):5155-63.
11. The tumor suppressor gene H-Rev107 functions as a novel Ca2+-independent cytosolic phospholipase A1/2 of the thiol hydrolase type. Uyama T, etal., J Lipid Res. 2009 Apr;50(4):685-93. doi: 10.1194/jlr.M800453-JLR200. Epub 2008 Dec 1.
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PMID:18614531   PMID:19136964   PMID:20100577   PMID:22134920   PMID:22825852   PMID:23012479  



Plaat3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81214,211,755 - 214,245,551 (+)NCBIGRCr8
mRatBN7.21204,782,608 - 204,816,397 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1204,782,729 - 204,817,667 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1213,132,708 - 213,166,583 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01220,227,923 - 220,261,595 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01212,918,978 - 212,952,652 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01222,844,238 - 222,877,180 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1222,844,144 - 222,877,193 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01229,831,484 - 229,864,268 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41210,281,109 - 210,315,280 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11784,429,015 - 84,429,766 (+)NCBI
Celera1202,309,606 - 202,343,352 (+)NCBICelera
RH 3.4 Map11522.4RGD
Cytogenetic Map1q43NCBI
PLAAT3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381163,574,462 - 63,616,927 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1163,573,195 - 63,616,883 (-)EnsemblGRCh38hg38GRCh38
GRCh371163,341,934 - 63,381,909 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361163,098,825 - 63,138,471 (-)NCBINCBI36Build 36hg18NCBI36
Build 341163,098,824 - 63,138,469NCBI
Celera1160,665,947 - 60,705,955 (-)NCBICelera
Cytogenetic Map11q12.3-q13.1NCBI
HuRef1159,671,244 - 59,711,239 (-)NCBIHuRef
CHM1_11163,224,977 - 63,264,973 (-)NCBICHM1_1
T2T-CHM13v2.01163,563,752 - 63,606,267 (-)NCBIT2T-CHM13v2.0
Plaat3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39197,534,824 - 7,565,914 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl197,534,824 - 7,565,910 (+)EnsemblGRCm39 Ensembl
GRCm38197,557,459 - 7,588,545 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl197,557,459 - 7,588,545 (+)EnsemblGRCm38mm10GRCm38
MGSCv37197,631,949 - 7,663,035 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36197,624,503 - 7,655,590 (+)NCBIMGSCv36mm8
Celera197,328,970 - 7,360,466 (+)NCBICelera
Cytogenetic Map19ANCBI
cM Map195.33NCBI
PLAAT3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2964,796,219 - 64,840,899 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11165,842,365 - 65,886,139 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01158,931,593 - 58,971,269 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11162,282,487 - 62,322,729 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1162,282,487 - 62,322,736 (-)Ensemblpanpan1.1panPan2
PLAAT3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11853,367,441 - 53,412,165 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1853,368,030 - 53,398,290 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1851,974,996 - 52,019,579 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01854,412,950 - 54,444,795 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1854,412,942 - 54,446,925 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11853,515,271 - 53,547,575 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01853,090,229 - 53,122,000 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01853,876,461 - 53,909,032 (+)NCBIUU_Cfam_GSD_1.0
Plaat3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244049479,067,359 - 9,082,123 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365995,521,186 - 5,524,472 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365995,509,723 - 5,524,837 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PLAAT3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl28,413,388 - 8,444,595 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.128,410,540 - 8,444,604 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.227,653,458 - 7,683,817 (+)NCBISscrofa10.2Sscrofa10.2susScr3
PLAAT3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1110,632,342 - 10,660,757 (+)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_023666038107,972,357 - 108,007,746 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0

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Variants in Plaat3
227 total Variants

Predicted Target Of
Summary Value
Count of predictions:110
Count of miRNA genes:99
Interacting mature miRNAs:105
Transcripts:ENSRNOT00000032879
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


1 to 10 of 84 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
1578778Pur4Proteinuria QTL 43.30.003urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)1150700247252085048Rat
1354646Kidm18Kidney mass QTL 185.7kidney mass (VT:0002707)calculated kidney weight (CMO:0000160)1151162512256448636Rat
1357335Bw39Body weight QTL 393.3body mass (VT:0001259)body weight (CMO:0000012)1197814409242814409Rat
1578780Cm52Cardiac mass QTL 523.30.0001heart mass (VT:0007028)heart wet weight (CMO:0000069)181591954219808434Rat
2302375Bw83Body weight QTL 834.870.0002body mass (VT:0001259)body weight (CMO:0000012)1197697768242697768Rat
1354652Kidm20Kidney mass QTL 204.3kidney mass (VT:0002707)calculated kidney weight (CMO:0000160)1177227632256448636Rat
2293674Bss39Bone structure and strength QTL 397.10.0001femur strength trait (VT:0010010)femur total energy absorbed before break (CMO:0001677)1201554356246554356Rat
2302378Insul11Insulin level QTL 113.25blood insulin amount (VT:0001560)serum insulin level (CMO:0000358)1144267353251128347Rat
1354653Despr9Despair related QTL 90.00019locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)1167909849212909849Rat
2293673Bss27Bone structure and strength QTL 2718.630.0001femur morphology trait (VT:0000559)femur midshaft cortical cross-sectional area (CMO:0001663)1171629477216629477Rat

1 to 10 of 84 rows
RH142176  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21204,808,695 - 204,808,890 (+)MAPPERmRatBN7.2
Rnor_6.01222,869,479 - 222,869,673NCBIRnor6.0
Rnor_5.01229,856,567 - 229,856,761UniSTSRnor5.0
RGSC_v3.41210,307,580 - 210,307,774UniSTSRGSC3.4
Celera1202,335,649 - 202,335,843UniSTS
RH 3.4 Map11522.4UniSTS
Cytogenetic Map1q43UniSTS




alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 113 91 90 59 25 59 6 218 97 93 45 60 31



Ensembl Acc Id: ENSRNOT00000032879   ⟹   ENSRNOP00000038045
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1204,782,729 - 204,817,667 (+)Ensembl
Rnor_6.0 Ensembl1222,844,144 - 222,877,193 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000090872   ⟹   ENSRNOP00000068660
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1204,786,024 - 204,817,667 (+)Ensembl
Rnor_6.0 Ensembl1222,861,777 - 222,877,047 (+)Ensembl
RefSeq Acc Id: NM_017060   ⟹   NP_058756
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81214,211,879 - 214,245,551 (+)NCBI
mRatBN7.21204,782,724 - 204,816,396 (+)NCBI
Rnor_6.01222,844,238 - 222,877,179 (+)NCBI
Rnor_5.01229,831,484 - 229,864,268 (+)NCBI
RGSC_v3.41210,281,109 - 210,315,280 (+)RGD
Celera1202,309,606 - 202,343,352 (+)RGD
Sequence:
RefSeq Acc Id: XM_006230687   ⟹   XP_006230749
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81214,215,465 - 214,245,551 (+)NCBI
mRatBN7.21204,786,450 - 204,816,397 (+)NCBI
Rnor_6.01222,847,244 - 222,877,180 (+)NCBI
Rnor_5.01229,831,484 - 229,864,268 (+)NCBI
Sequence:
RefSeq Acc Id: XM_039101104   ⟹   XP_038957032
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81214,211,898 - 214,245,551 (+)NCBI
mRatBN7.21204,782,775 - 204,816,397 (+)NCBI
RefSeq Acc Id: XM_039101108   ⟹   XP_038957036
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81214,211,755 - 214,245,551 (+)NCBI
mRatBN7.21204,782,608 - 204,816,397 (+)NCBI
1 to 10 of 10 rows
Protein RefSeqs NP_058756 (Get FASTA)   NCBI Sequence Viewer  
  XP_006230749 (Get FASTA)   NCBI Sequence Viewer  
  XP_038957032 (Get FASTA)   NCBI Sequence Viewer  
  XP_038957036 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein BAH08634 (Get FASTA)   NCBI Sequence Viewer  
  EDM12684 (Get FASTA)   NCBI Sequence Viewer  
  EDM12685 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000038045
  ENSRNOP00000105263
GenBank Protein P53817 (Get FASTA)   NCBI Sequence Viewer  
1 to 10 of 10 rows
RefSeq Acc Id: NP_058756   ⟸   NM_017060
- UniProtKB: B7X6T2 (UniProtKB/Swiss-Prot),   P53817 (UniProtKB/Swiss-Prot),   A0A8L2QJ20 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006230749   ⟸   XM_006230687
- Peptide Label: isoform X1
- UniProtKB: A0A0G2JTD0 (UniProtKB/TrEMBL),   A0A8L2QJ20 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000068660   ⟸   ENSRNOT00000090872
Ensembl Acc Id: ENSRNOP00000038045   ⟸   ENSRNOT00000032879
RefSeq Acc Id: XP_038957036   ⟸   XM_039101108
- Peptide Label: isoform X3
LRAT

Name Modeler Protein Id AA Range Protein Structure
AF-P53817-F1-model_v2 AlphaFold P53817 1-160 view protein structure


eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

RGD ID:13690722
Promoter ID:EPDNEW_R1247
Type:initiation region
Name:Pla2g16_1
Description:phospholipase A2, group XVI
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01222,844,208 - 222,844,268EPDNEW


1 to 20 of 20 rows
Database
Acc Id
Source(s)
BioCyc Gene G2FUF-56543 BioCyc
Ensembl Genes ENSRNOG00000021206 Ensembl, ENTREZGENE
Ensembl Transcript ENSRNOT00000032879 ENTREZGENE
  ENSRNOT00000163362 ENTREZGENE
Gene3D-CATH endopeptidase domain like (from Nostoc punctiforme) UniProtKB/Swiss-Prot
InterPro H-rev107_PLA/AT UniProtKB/Swiss-Prot
  LRAT_dom UniProtKB/Swiss-Prot
KEGG Report rno:24913 UniProtKB/Swiss-Prot
NCBI Gene 24913 ENTREZGENE
PANTHER HRAS-LIKE SUPPRESSOR - RELATED UniProtKB/Swiss-Prot
  PHOSPHOLIPASE A AND ACYLTRANSFERASE 3 UniProtKB/Swiss-Prot
Pfam LRAT UniProtKB/Swiss-Prot
PhenoGen Plaat3 PhenoGen
PROSITE LRAT UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000021206 RatGTEx
UniProt A0A0G2JTD0 ENTREZGENE, UniProtKB/TrEMBL
  A0A8L2QJ20 ENTREZGENE, UniProtKB/TrEMBL
  B7X6T2 ENTREZGENE
  P53817 ENTREZGENE, UniProtKB/Swiss-Prot
UniProt Secondary B7X6T2 UniProtKB/Swiss-Prot
1 to 20 of 20 rows


Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2019-08-14 Plaat3  phospholipase A and acyltransferase 3  Pla2g16  phospholipase A2, group XVI  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-10-16 Pla2g16  phospholipase A2, group XVI  Hrasls3  HRAS like suppressor 3  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-03-30 Hrasls3  HRAS like suppressor 3    HRAS like suppressor   Name updated 1299863 APPROVED
2003-12-05 Hrasls3  HRAS like suppressor   Hrev107    Symbol updated 61478 APPROVED
2002-11-06 Hrasls3  HRAS like suppressor   Hrev107  Hras-revertant gene 107  Symbol and Name updated 625702 APPROVED
2002-06-10 Hrev107  Hras-revertant gene 107      Symbol and Name status set to approved 70586 APPROVED

Note Type Note Reference
gene_cellular_localization localizes to both cell membrane and cytoplasm 708597
gene_expression specifically expressed in H-ras resistant fibroblasts 708597
gene_protein molecular weight of 18 kDa 708597