Gene: Fads2 (fatty acid desaturase 2) Rattus norvegicus
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Symbol: Fads2
Name: fatty acid desaturase 2
Description: ENCODES a protein that exhibits stearoyl-CoA 9-desaturase activity (ortholog); INVOLVED IN lipid metabolic process (inferred); oxidation-reduction process (inferred); unsaturated fatty acid biosynthetic process (inferred); PARTICIPATES IN alpha-linoleic acid metabolic pathway; linoleic acid metabolic pathway; eicosanoid signaling pathway via peroxisome proliferator-activated receptor gamma; ASSOCIATED WITH Chemical and Drug Induced Liver Injury (ortholog); Colorectal Neoplasms (ortholog); lipid storage disease (ortholog); FOUND IN endoplasmic reticulum membrane (inferred); integral component of membrane (inferred); INTERACTS WITH (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE; 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: acyl-CoA 6-desaturase; D6D; delta(6) desaturase; delta(6) fatty acid desaturase; delta-6 desaturase; delta-6 fatty acid desaturase; Fadsd6; fatty acid desaturase 6; MGC93365
Orthologs:
Homo sapiens (human) : FADS2 (fatty acid desaturase 2)  HGNC  Alliance
Mus musculus (house mouse) : Fads2 (fatty acid desaturase 2)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Fads2 (fatty acid desaturase 2)
Pan paniscus (bonobo/pygmy chimpanzee) : FADS2 (fatty acid desaturase 2)
Canis lupus familiaris (dog) : FADS2 (fatty acid desaturase 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Fads2 (fatty acid desaturase 2)
Sus scrofa (pig) : FADS2 (fatty acid desaturase 2)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
NCBI Annotation Information: Annotation category: suggests misassembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01225,906,582 - 226,152,568 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01233,060,345 - 233,097,316 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Rnor_5.01232,857,004 - 232,857,656 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41212,512,691 - 212,542,622 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11212,671,121 - 212,701,051 (-)NCBI
Celera1204,204,027 - 204,242,387 (-)NCBICelera
Cytogenetic Map1q43NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model

Annotation    (Toggle Annotation Detail/Summary View)

Disease Annotations
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Genomics

Comparative Map Data
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
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Strain Variation

Strain Sequence Variants (Rnor 5.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
  
More on Fads2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 68339
Created: 2001-07-11
Species: Rattus norvegicus
Last Modified: 2019-01-30
Status: ACTIVE



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