Gene: Fads2 (fatty acid desaturase 2) Rattus norvegicus
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Symbol: Fads2
Name: fatty acid desaturase 2
Description: ENCODES a protein that exhibits stearoyl-CoA 9-desaturase activity (ortholog); INVOLVED IN lipid metabolic process (inferred); oxidation-reduction process (inferred); unsaturated fatty acid biosynthetic process (inferred); PARTICIPATES IN alpha-linoleic acid metabolic pathway; linoleic acid metabolic pathway; eicosanoid signaling pathway via peroxisome proliferator-activated receptor gamma; ASSOCIATED WITH Chemical and Drug Induced Liver Injury (ortholog); Colorectal Neoplasms (ortholog); lipid storage disease (ortholog); FOUND IN endoplasmic reticulum membrane (inferred); integral component of membrane (inferred); INTERACTS WITH (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE; 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: D6D; delta(6) desaturase; delta(6) fatty acid desaturase; delta-6 desaturase; delta-6 fatty acid desaturase; Fadsd6; fatty acid desaturase 6; MGC93365
Orthologs:
Homo sapiens (human) : FADS2 (fatty acid desaturase 2)  HGNC  Alliance
Mus musculus (house mouse) : Fads2 (fatty acid desaturase 2)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Fads2 (fatty acid desaturase 2)
Pan paniscus (bonobo/pygmy chimpanzee) : FADS2 (fatty acid desaturase 2)
Canis lupus familiaris (dog) : FADS2 (fatty acid desaturase 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Fads2 (fatty acid desaturase 2)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
NCBI Annotation Information: Annotation category: suggests misassembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01225,906,582 - 226,152,568 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01233,060,345 - 233,097,316 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Rnor_5.01232,857,004 - 232,857,656 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41212,512,691 - 212,542,622 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11212,671,121 - 212,701,051 (-)NCBI
Celera1204,204,027 - 204,242,387 (-)NCBICelera
Cytogenetic Map1q43NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Fads2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 68339
Created: 2001-07-11
Species: Rattus norvegicus
Last Modified: 2018-08-08
Status: ACTIVE