Irf7 (interferon regulatory factor 7)

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Gene: Irf7 (interferon regulatory factor 7) Rattus norvegicus

Analyze

Symbol:

Irf7

Name:

interferon regulatory factor 7

RGD ID:

1307828

Description:

Predicted to have DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in several processes, including defense response to other organism; positive regulation of type I interferon production; and regulation of signal transduction. Predicted to localize to cytosol and nucleoplasm. Human ortholog(s) of this gene implicated in immunodeficiency 39. Orthologous to human IRF7 (interferon regulatory factor 7); PARTICIPATES IN hepatitis C pathway; influenza A pathway; measles pathway; INTERACTS WITH 1,2-dimethylhydrazine; 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine.

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Also known as:

LOC293624; MGC125013

RGD Orthologs

Human

Mouse

Chinchilla

Dog

Squirrel

Pig

Green Monkey

Naked Mole-Rat

Alliance Genes

More Info

more info ...

Latest Assembly:

Rnor_6.0 - RGSC Genome Assembly v6.0

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mRatBN7.2	1	196,367,380 - 196,370,943 (-)	NCBI
Rnor_6.0 Ensembl	1	214,248,837 - 214,252,456 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_6.0	1	214,249,388 - 214,252,909 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_5.0	1	221,166,926 - 221,170,447 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	1	201,456,689 - 201,459,756 (-)	NCBI	RGSC3.4		rn4	RGSC3.4
RGSC_v3.1	1	201,607,693 - 201,611,125 (-)	NCBI
Celera	1	194,001,244 - 194,004,312 (-)	NCBI		Celera
Cytogenetic Map	1	q41	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

COVID-19 (ISO)

developmental and epileptic encephalopathy (ISO)

early infantile epileptic encephalopathy (ISO)

Human Influenza (ISO)

immunodeficiency 39 (ISO)

Inflammation (ISO)

lymphocytic choriomeningitis (ISO)

neuronal ceroid lipofuscinosis (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(S)-nicotine (ISO)

1,1-dichloroethene (ISO)

1,2-dimethylhydrazine (EXP,ISO)

17alpha-ethynylestradiol (EXP,ISO)

17beta-estradiol (ISO)

2,2',4,4'-Tetrabromodiphenyl ether (ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

2-hydroxypropanoic acid (ISO)

3,3',4,4',5-pentachlorobiphenyl (EXP)

3,3',5,5'-tetrabromobisphenol A (EXP)

4-(ethoxymethylene)-2-phenyloxazol-5-one (EXP)

4-hydroxynon-2-enal (ISO)

5-aza-2'-deoxycytidine (ISO)

6-propyl-2-thiouracil (EXP)

6alpha-methylprednisolone (ISO)

acetamide (EXP)

aflatoxin B1 (ISO)

all-trans-retinoic acid (ISO)

Aroclor 1254 (ISO)

arsane (ISO)

arsenic atom (ISO)

azathioprine (ISO)

benzene (ISO)

benzo[a]pyrene (ISO)

benzo[a]pyrene diol epoxide I (ISO)

benzo[b]fluoranthene (ISO)

beta-naphthoflavone (EXP)

bis(2-ethylhexyl) phthalate (ISO)

bisphenol A (EXP,ISO)

buspirone (EXP)

C60 fullerene (EXP)

cadmium dichloride (EXP)

calcitriol (ISO)

carbon nanotube (ISO)

ceric oxide (ISO)

chloroprene (EXP)

cholesterol (ISO)

chromium(6+) (ISO)

copper atom (EXP)

copper(0) (EXP)

cyclosporin A (ISO)

dichloroacetic acid (ISO)

diclofenac (ISO)

diethyl malate (ISO)

diethyl maleate (EXP)

diethylstilbestrol (EXP,ISO)

dorsomorphin (ISO)

doxorubicin (ISO)

endosulfan (EXP)

ethanol (EXP,ISO)

ethyl methanesulfonate (ISO)

fenofibrate (ISO)

ferric oxide (ISO)

finasteride (EXP)

folic acid (ISO)

formaldehyde (ISO)

fructose (ISO)

furan (EXP)

genistein (ISO)

gentamycin (EXP)

geraniol (ISO)

hydralazine (ISO)

hydroxychloroquine (ISO)

isoflavones (ISO)

linuron (ISO)

lipopolysaccharide (ISO)

metam (ISO)

metformin (ISO)

methyl methanesulfonate (ISO)

mitoxantrone (ISO)

N-nitrosodiethylamine (EXP)

N-nitrosomorpholine (EXP)

nickel atom (ISO)

nickel dichloride (ISO)

nicotine (ISO)

nitrates (EXP)

orphenadrine (EXP)

oxaliplatin (EXP)

paclitaxel (EXP,ISO)

paracetamol (ISO)

pentachlorophenol (ISO)

perfluorononanoic acid (ISO)

phenobarbital (EXP)

phenylephrine (EXP)

pirinixic acid (EXP,ISO)

poly(I:C) (EXP,ISO)

prednisolone (ISO)

pregnenolone 16alpha-carbonitrile (EXP)

rac-lactic acid (ISO)

raloxifene (EXP)

rotenone (EXP)

SB 431542 (ISO)

silicon dioxide (ISO)

silver atom (ISO)

silver(0) (ISO)

sodium aurothiomalate (ISO)

Soman (EXP)

succimer (ISO)

sulforaphane (ISO)

sulindac (EXP)

sunitinib (ISO)

tamibarotene (ISO)

tamoxifen (ISO)

tert-butyl hydroperoxide (ISO)

Tesaglitazar (EXP)

testosterone (ISO)

tetrachloromethane (ISO)

tetraphene (ISO)

thapsigargin (ISO)

theophylline (ISO)

thioacetamide (EXP)

titanium dioxide (ISO)

tofacitinib (ISO)

topotecan (EXP)

trimellitic anhydride (EXP)

troglitazone (ISO)

tunicamycin (ISO)

valproic acid (ISO)

vinclozolin (EXP)

XL147 (ISO)

zalcitabine (EXP)

zidovudine (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

defense response to virus (ISO)

immune system process (IBA)

immunoglobulin mediated immune response (ISO)

positive regulation of interferon-alpha production (ISO)

positive regulation of interferon-beta production (ISO)

positive regulation of transcription by RNA polymerase II (ISO)

positive regulation of transcription, DNA-templated (ISO)

positive regulation of type I interferon production (ISO)

positive regulation of type I interferon-mediated signaling pathway (ISO)

regulation of adaptive immune response (ISO)

regulation of gene expression (ISO)

regulation of MyD88-dependent toll-like receptor signaling pathway (ISO)

regulation of MyD88-independent toll-like receptor signaling pathway (ISO)

regulation of transcription by RNA polymerase II (IBA)

type I interferon signaling pathway (ISO)

Cellular Component

cytoplasm (ISO)

cytosol (IEA,ISO)

nucleoplasm (IEA,ISO)

nucleus (IBA,ISO)

Molecular Function

cis-regulatory region sequence-specific DNA binding (ISO)

DNA binding (ISO)

DNA-binding transcription factor activity, RNA polymerase II-specific (IBA,ISO)

protein binding (ISO)

RNA polymerase II cis-regulatory region sequence-specific DNA binding (IBA,ISO)

sequence-specific double-stranded DNA binding (ISO)

Molecular Pathway Annotations Click to see Annotation Detail View

hepatitis C pathway (IEA)

influenza A pathway (IEA)

measles pathway (IEA)

Retinoic acid-inducible gene (RIG) I-like receptor signaling pathway (IEA)

Toll-like receptor signaling pathway (IEA)

References

References - curated


1.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	GOA data from the GO Consortium
3.	Li W, etal., J Virol. 2014 Jul;88(13):7578-88. doi: 10.1128/JVI.03117-13. Epub 2014 Apr 23.
4.	MGD data from the GO Consortium
5.	Pipeline to import KEGG annotations from KEGG into RGD
6.	RGD automated data pipeline
7.	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:12374802	PMID:12477932	PMID:15800576	PMID:16127453	PMID:17404045	PMID:17618271	PMID:19176627	PMID:21478870	PMID:22065573	PMID:23036922	PMID:23042151	PMID:23160154
PMID:23729669	PMID:23956435	PMID:27129230	PMID:33152351

Genomics

Comparative Map Data

Irf7
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mRatBN7.2	1	196,367,380 - 196,370,943 (-)	NCBI
Rnor_6.0 Ensembl	1	214,248,837 - 214,252,456 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_6.0	1	214,249,388 - 214,252,909 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_5.0	1	221,166,926 - 221,170,447 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	1	201,456,689 - 201,459,756 (-)	NCBI	RGSC3.4		rn4	RGSC3.4
RGSC_v3.1	1	201,607,693 - 201,611,125 (-)	NCBI
Celera	1	194,001,244 - 194,004,312 (-)	NCBI		Celera
Cytogenetic Map	1	q41	NCBI

IRF7
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38.p13 Ensembl	11	612,553 - 615,983 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh38	11	612,555 - 615,999 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh37	11	612,555 - 615,950 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	11	602,555 - 605,999 (-)	NCBI	NCBI36		hg18	NCBI36
Build 34	11	602,590 - 605,650	NCBI
Celera	11	677,701 - 681,146 (-)	NCBI
Cytogenetic Map	11	p15.5	NCBI
HuRef	11	427,860 - 431,281 (-)	NCBI		HuRef
CHM1_1	11	611,595 - 615,009 (-)	NCBI		CHM1_1

Irf7
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	7	140,843,096 - 140,846,412 (-)	NCBI	GRCm39		mm39
GRCm39 Ensembl	7	140,842,619 - 140,846,394 (-)	Ensembl
GRCm38	7	141,263,183 - 141,266,499 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	7	141,262,706 - 141,266,481 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	7	148,449,088 - 148,452,300 (-)	NCBI	GRCm37		mm9	NCBIm37
MGSCv36	7	141,114,509 - 141,117,721 (-)	NCBI			mm8
Celera	7	141,056,921 - 141,060,133 (-)	NCBI		Celera
Cytogenetic Map	7	F5	NCBI

Irf7
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955476	11,443,272 - 11,445,657 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955476	11,442,781 - 11,445,706 (+)	NCBI	ChiLan1.0	ChiLan1.0

IRF7
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Dog10K_Boxer_Tasha	18	25,356,590 - 25,359,121 (-)	NCBI
ROS_Cfam_1.0	18	26,292,147 - 26,294,695 (-)	NCBI
UMICH_Zoey_3.1	18	25,801,663 - 25,804,207 (-)	NCBI
UNSW_CanFamBas_1.0	18	25,446,631 - 25,449,156 (-)	NCBI
UU_Cfam_GSD_1.0	18	26,058,831 - 26,061,390 (-)	NCBI

Irf7
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_ltri_2	NW_024404947	445,336 - 448,848 (-)	NCBI
SpeTri2.0	NW_004936888	445,340 - 448,801 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

IRF7
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	2	371,606 - 375,381 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	2	372,235 - 375,572 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	2	299,457 - 302,151 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

IRF7
(Chlorocebus sabaeus - African green monkey)

Vervet Assembly	Chr	Position (strand)	Source	Genome Browsers
Vervet Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	1	430,412 - 433,959 (-)	NCBI
ChlSab1.1 Ensembl	1	429,310 - 432,925 (-)	Ensembl

Irf7
(Heterocephalus glaber - naked mole-rat)

Molerat Assembly	Chr	Position (strand)	Source	Genome Browsers
Molerat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla 1.0	NW_004624766	21,850,211 - 21,853,189 (+)	NCBI

Position Markers

RH129676

Rat Assembly	Chr	Position (strand)	Source	JBrowse
Rnor_6.0	1	214,249,417 - 214,249,620	NCBI	Rnor6.0
Rnor_5.0	1	221,166,955 - 221,167,158	UniSTS	Rnor5.0
RGSC_v3.4	1	201,456,718 - 201,456,921	UniSTS	RGSC3.4
Celera	1	194,001,273 - 194,001,476	UniSTS
RH 3.4 Map	1	1437.31	UniSTS
Cytogenetic Map	1	q41	UniSTS

PMC114617P2

Rat Assembly	Chr	Position (strand)	Source	JBrowse
Rnor_6.0	1	214,250,927 - 214,251,948	NCBI	Rnor6.0
Rnor_5.0	1	221,168,465 - 221,169,486	UniSTS	Rnor5.0
RGSC_v3.4	1	201,458,228 - 201,459,249	UniSTS	RGSC3.4
Celera	1	194,002,784 - 194,003,805	UniSTS
Cytogenetic Map	1	q41	UniSTS

PMC154027P4

Rat Assembly	Chr	Position (strand)	Source	JBrowse
Rnor_6.0	1	214,249,672 - 214,250,139	NCBI	Rnor6.0
Rnor_5.0	1	221,167,210 - 221,167,677	UniSTS	Rnor5.0
RGSC_v3.4	1	201,456,973 - 201,457,440	UniSTS	RGSC3.4
Celera	1	194,001,528 - 194,001,996	UniSTS
Cytogenetic Map	1	q41	UniSTS

QTLs in Region (Rnor_6.0)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
70209	Niddm23	Non-insulin dependent diabetes mellitus QTL 23	2.82		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	1	99983293	216325819	Rat
619613	Bp77	Blood pressure QTL 77		0.01	arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	1	175447029	220447029	Rat
619613	Bp77	Blood pressure QTL 77		0.01	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	175447029	220447029	Rat
619614	Bp78	Blood pressure QTL 78		0.001	arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	1	184419946	215097919	Rat
619614	Bp78	Blood pressure QTL 78		0.001	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	184419946	215097919	Rat
631205	Bp196	Blood pressure QTL 196	4	0.0001	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	1	126240667	217054291	Rat
631214	Bw61	Body weight QTL61	3.4	0.0001	intramuscular adipose amount (VT:0010044)	intramuscular fat area (CMO:0001162)	1	193220385	238220385	Rat
2302378	Insul11	Insulin level QTL 11	3.25		blood insulin amount (VT:0001560)	serum insulin level (CMO:0000358)	1	156446196	274977688	Rat
631260	Tcas2	Tongue tumor susceptibility QTL 2	4.93		tongue integrity trait (VT:0010553)	number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)	1	210019247	217054418	Rat
70160	Bw18	Body weight QTL 18	5.7		body mass (VT:0001259)	body weight (CMO:0000012)	1	156446196	214277437	Rat
70163	Bw20	Body weight QTL 20	5.1		body mass (VT:0001259)	body weight (CMO:0000012)	1	189514504	234514504	Rat
724531	Uae5	Urinary albumin excretion QTL 5	4		urine albumin amount (VT:0002871)	urine albumin level (CMO:0000130)	1	161321152	273792054	Rat
724559	Pancm1	Pancreatic morphology QTL 1	7.1		islet of Langerhans morphology trait (VT:0005215)	pancreatic islet damage composite score (CMO:0001156)	1	198585664	236763415	Rat
724562	Rends1	Renal damage susceptibility QTL 1		0.05	kidney glomerulus integrity trait (VT:0010546)	index of glomerular damage (CMO:0001135)	1	137787261	236763528	Rat
1331749	Hrtrt11	Heart rate QTL 11	2.973		heart pumping trait (VT:2000009)	heart rate (CMO:0000002)	1	99983293	216213510	Rat
737828	Hcas3	Hepatocarcinoma susceptibility QTL 3	4.9		liver integrity trait (VT:0010547)	liver tumorous lesion volume to total liver volume ratio (CMO:0001082)	1	156446196	243311614	Rat
631670	Iddm10	Insulin dependent diabetes mellitus QTL 10	1.9		blood glucose amount (VT:0000188)	plasma glucose level (CMO:0000042)	1	189514504	214277437	Rat
737977	Bp160	Blood pressure QTL 160		0.001	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	1	197963658	242963658	Rat
1354580	Scort1	Serum corticosterone level QTL 1	3.4		blood corticosterone amount (VT:0005345)	blood corticosterone level (CMO:0001172)	1	167394665	278228889	Rat
1582206	Kidm33	Kidney mass QTL 33	6.9		kidney mass (VT:0002707)	both kidneys wet weight to body weight ratio (CMO:0000340)	1	205603081	244401301	Rat
731168	Bp154	Blood pressure QTL 154	3.4		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	100131562	236763528	Rat
738032	Hcas5	Hepatocarcinoma susceptibility QTL 5	3.12		liver integrity trait (VT:0010547)	liver tumorous lesion number (CMO:0001068)	1	191825895	279986079	Rat
631549	Bp89	Blood pressure QTL 89	5.7		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	130779320	219238476	Rat
1302787	Stl25	Serum triglyceride level QTL 25	2.7	0.0073	blood triglyceride amount (VT:0002644)	plasma triglyceride level (CMO:0000548)	1	197187728	230420772	Rat
1598853	Memor3	Memory QTL 3	4.5		exploratory behavior trait (VT:0010471)	total horizontal distance resulting from voluntary locomotion in an experimental apparatus (CMO:0001443)	1	153834077	232297227	Rat
2300161	Bmd43	Bone mineral density QTL 43	8.4	0.0001	femur mineral mass (VT:0010011)	volumetric bone mineral density (CMO:0001553)	1	189170900	234170900	Rat
2300174	Bmd42	Bone mineral density QTL 42	8.4	0.0001	lumbar vertebra mineral mass (VT:0010511)	bone mineral density (CMO:0001226)	1	189170900	234170900	Rat
2300187	Bmd41	Bone mineral density QTL 41	8.9	0.0001	femur mineral mass (VT:0010011)	volumetric bone mineral density (CMO:0001553)	1	189170900	234170900	Rat
2293654	Bss30	Bone structure and strength QTL 30	32.65	0.0001	femur strength trait (VT:0010010)	femur midshaft polar moment of inertia (CMO:0001669)	1	189170900	234170900	Rat
2293673	Bss27	Bone structure and strength QTL 27	18.63	0.0001	femur morphology trait (VT:0000559)	femur midshaft cortical cross-sectional area (CMO:0001663)	1	189170900	234170900	Rat
2293677	Bss41	Bone structure and strength QTL 41	9.38	0.0001	lumbar vertebra size trait (VT:0010518)	lumbar vertebra cross-sectional area (CMO:0001689)	1	189170900	234170900	Rat
2293689	Bss47	Bone structure and strength QTL 47	7.25	0.0001	lumbar vertebra size trait (VT:0010518)	lumbar vertebra trabecular cross-sectional area (CMO:0001692)	1	189170900	234170900	Rat
2293693	Bss22	Bone structure and strength QTL 22	33.52	0.0001	femur morphology trait (VT:0000559)	femur cross-sectional area (CMO:0001661)	1	189170900	234170900	Rat
631838	Niddm36	Non-insulin dependent diabetes mellitus QTL 36		0.01	insulin secretion trait (VT:0003564)	calculated pancreatic islet insulin release measurement (CMO:0001217)	1	205195290	250195290	Rat
634312	Bp143	Blood pressure QTL 143	3	0.0002	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	198446729	240017341	Rat
634314	Niddm44	Non-insulin dependent diabetes mellitus QTL 44			blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	1	49578693	217054291	Rat
634321	Hc1	Hypercalciuria QTL 1	2.91		urine calcium amount (VT:0002985)	urine calcium excretion rate (CMO:0000763)	1	193968438	261264776	Rat
634338	Hcar4	Hepatocarcinoma resistance QTL 4	4.6		liver integrity trait (VT:0010547)	liver tumorous lesion number to liver area ratio (CMO:0001210)	1	210960636	236763528	Rat
1600363	Hc6	Hypercalciuria QTL 6	2.7		urine calcium amount (VT:0002985)	urine calcium excretion rate (CMO:0000763)	1	195598053	265002735	Rat
1600380	Niddm70	Non-insulin dependent diabetes mellitus QTL 70	3.1	0.0008	blood insulin amount (VT:0001560)	plasma insulin level (CMO:0000342)	1	194554354	239554354	Rat
1600388	Niddm67	Non-insulin dependent diabetes mellitus QTL 67	5.84	0.000004	blood glucose amount (VT:0000188)	blood glucose level area under curve (AUC) (CMO:0000350)	1	213476630	278978026	Rat
1600395	Niddm69	Non-insulin dependent diabetes mellitus QTL 69	4.14	0.0002	blood insulin amount (VT:0001560)	plasma insulin level (CMO:0000342)	1	213476630	278978026	Rat
1600396	Niddm68	Non-insulin dependent diabetes mellitus QTL 68	4.97	0.0003	blood glucose amount (VT:0000188)	blood glucose level area under curve (AUC) (CMO:0000350)	1	213476630	278978026	Rat
1578759	Uae30	Urinary albumin excretion QTL 30	3.3	0.003	urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	1	161321256	273791893	Rat
1578763	Kidm29	Kidney mass QTL 29	3.3	0.0001	kidney mass (VT:0002707)	both kidneys wet weight (CMO:0000085)	1	196395041	282763074	Rat
1578778	Pur4	Proteinuria QTL 4	3.3	0.003	total urine protein amount (VT:0000032)	urine total protein excretion rate (CMO:0000756)	1	161321256	273791893	Rat
1578780	Cm52	Cardiac mass QTL 52	3.3	0.0001	heart mass (VT:0007028)	heart wet weight (CMO:0000069)	1	82788437	239853971	Rat
1300145	Rf7	Renal function QTL 7	2.96		urine creatinine amount (VT:0010540)	urine creatinine level (CMO:0000125)	1	201146802	241482368	Rat
1354591	Cm36	Cardiac mass QTL 36	4.1		heart left ventricle mass (VT:0007031)	calculated heart weight (CMO:0000073)	1	108986301	219232156	Rat
1354602	Bw35	Body weight QTL 35	12.2		body mass (VT:0001259)	body weight (CMO:0000012)	1	161784169	219232156	Rat
1354606	Bp246	Blood pressure QTL 246	3.6		arterial blood pressure trait (VT:2000000)	pulse pressure (CMO:0000292)	1	108986301	238830534	Rat
1354610	Bw34	Body weight QTL 34	4.1		body mass (VT:0001259)	body weight (CMO:0000012)	1	161784169	278228889	Rat
1354615	Cm32	Cardiac mass QTL 32	5.2		heart left ventricle mass (VT:0007031)	heart left ventricle wet weight (CMO:0000071)	1	108986301	219232156	Rat
1354618	Kidm15	Kidney mass QTL 15	5		kidney mass (VT:0002707)	left kidney wet weight (CMO:0000083)	1	167394665	219232156	Rat
1354620	Kidm19	Kidney mass QTL 19	4		kidney mass (VT:0002707)	calculated kidney weight (CMO:0000160)	1	161784169	219232156	Rat
1354624	Cm35	Cardiac mass QTL35	5.7		heart left ventricle mass (VT:0007031)	calculated heart weight (CMO:0000073)	1	192639698	278228889	Rat
1354634	Kidm12	Kidney mass QTL 12	3.9		kidney mass (VT:0002707)	right kidney wet weight (CMO:0000082)	1	161784169	219232156	Rat
1354636	Lmblg1	Limb length QTL 1	6.4		tibia length (VT:0004357)	tibia length (CMO:0000450)	1	161784169	219232156	Rat
1354646	Kidm18	Kidney mass QTL 18	5.7		kidney mass (VT:0002707)	calculated kidney weight (CMO:0000160)	1	161784169	278228889	Rat
1354652	Kidm20	Kidney mass QTL 20	4.3		kidney mass (VT:0002707)	calculated kidney weight (CMO:0000160)	1	192639698	278228889	Rat
1354653	Despr9	Despair related QTL 9		0.00019	locomotor behavior trait (VT:0001392)	amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)	1	185390068	230390068	Rat
1354661	Bw33	Body weight QTL 33	5.2		body mass (VT:0001259)	body weight (CMO:0000012)	1	161784169	278228889	Rat
1359018	Hrtrt20	Heart rate QTL 20	3.08		heart pumping trait (VT:2000009)	heart rate (CMO:0000002)	1	201358068	221983732	Rat
1558658	Bw59	Body weight QTL 59	3.5	0.0003	body mass (VT:0001259)	body weight (CMO:0000012)	1	196738546	241738546	Rat
1549837	Hcar15	Hepatocarcinoma resistance QTL 15		0.05	liver integrity trait (VT:0010547)	liver tumorous lesion number (CMO:0001068)	1	163796316	282763074	Rat
1358191	Ept10	Estrogen-induced pituitary tumorigenesis QTL 10	3.8		pituitary gland mass (VT:0010496)	pituitary gland wet weight (CMO:0000853)	1	210360774	264802828	Rat
2292220	Bp306	Blood pressure QTL 306	3.47	0.00087	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	174905700	264802994	Rat
2292222	Bp307	Blood pressure QTL 307	3.06	0.0014	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	174905700	233490237	Rat
2293083	Iddm25	Insulin dependent diabetes mellitus QTL 25	4.18		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	1	198655722	244992610	Rat
2312420	Pur17	Proteinuria QTL 17	7.1	0.0001	urine protein amount (VT:0005160)	urine total protein excretion rate (CMO:0000756)	1	167394665	238830534	Rat
2312564	Glom18	Glomerulus QTL 18	2.4	0.003	kidney glomerulus morphology trait (VT:0005325)	index of glomerular damage (CMO:0001135)	1	201358068	252480016	Rat
2303622	Vencon6	Ventilatory control QTL 6		0.001	respiration trait (VT:0001943)	respiration rate (CMO:0000289)	1	169971964	214971964	Rat
1358886	Bp260	Blood pressure QTL 260	3.67		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	1	161784422	246226103	Rat
1358898	Bp255	Blood pressure QTL 255	3.6		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	1	208517798	266948272	Rat
1549830	Bss1	Bone structure and strength QTL 1	4.8		femur strength trait (VT:0010010)	femur ultimate force (CMO:0001675)	1	190282646	235282646	Rat
1358294	Bw37	Body weight QTL 37	5	0.000011	body mass (VT:0001259)	body weight (CMO:0000012)	1	188850303	233850303	Rat
61341	Bp26	Blood pressure QTL 26			arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	137787261	236763528	Rat
61347	Bp197	Blood pressure QTL 197	4.2		arterial blood pressure trait (VT:2000000)	blood pressure measurement (CMO:0000003)	1	175462885	220462885	Rat
61348	Bp30	Blood pressure QTL 30	2.4		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	154337847	215828102	Rat
61378	Bp43	Blood pressure QTL 43	22.6		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	198572999	214277437	Rat
6480780	Insul18	Insulin level QTL 18	4.11		blood insulin amount (VT:0001560)	plasma insulin level (CMO:0000342)	1	206950905	218614387	Rat
6903303	Scl34	Serum cholesterol QTL 34	2.5	0.0033	blood cholesterol amount (VT:0000180)	plasma total cholesterol level (CMO:0000585)	1	197187728	238220385	Rat
8655655	Arrd2	Age-related retinal degeneration QTL 2	7.79		retinal layer morphology trait (VT:0003727)	percentage of study population developing retinopathy during a period of time (CMO:0002453)	1	202571665	264802994	Rat
7794788	Mcs32	Mammary carcinoma susceptibility QTL 32	2.61		mammary gland integrity trait (VT:0010552)	mammary tumor incidence/prevalence measurement (CMO:0000946)	1	122614824	262664716	Rat
7771612	Cm80	Cardiac mass QTL 80	8.4		heart left ventricle mass (VT:0007031)	heart left ventricle weight (CMO:0000776)	1	144634295	241482368	Rat
7421630	Bp362	Blood pressure QTL 362		0.001	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	1	125875758	262433692	Rat
8552891	Epfw5	Epididymal fat weight QTL 5	4.4		epididymal fat pad mass (VT:0010421)	epididymal fat pad weight to body weight ratio (CMO:0000658)	1	210652654	255652654	Rat
8655855	Arrd3	Age-related retinal degeneration QTL 3	3.07		lens clarity trait (VT:0001304)	cataract incidence/prevalence measurement (CMO:0001585)	1	202571665	264802994	Rat
10059590	Kidm44	Kidney mass QTL 44	3.42	0.025	kidney mass (VT:0002707)	both kidneys wet weight to body weight ratio (CMO:0000340)	1	210990171	255990171	Rat
10059597	Bp377	Blood pressure QTL 377	3.42	0.025	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	35377692	217372257	Rat
10059600	Bp378	Blood pressure QTL 378	3.08	0.05	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	194872362	239872362	Rat

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	114
Count of miRNA genes:	87
Interacting mature miRNAs:	95
Transcripts:	ENSRNOT00000023504
Prediction methods:	Microtar, Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

	alimentary part of gastrointestinal system	circulatory system	endocrine system	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	appendage
High
Medium	3	13	26	12	19	12			2	11	7	11
Low		22	27	25		25	8	11	44	24	30		8
Below cutoff		8	4	4		4			26		4

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001033691	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006230540	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006230541	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039107968	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AC118351	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC104686	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH473953	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ232130	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ232859	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JACYVU010000044	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Reference Sequences

RefSeq Acc Id:

ENSRNOT00000023504 ⟹ ENSRNOP00000023504

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0 Ensembl	1	214,248,837 - 214,252,456 (-)	Ensembl

RefSeq Acc Id:

NM_001033691 ⟹ NP_001028863

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	1	196,367,380 - 196,370,447 (-)	NCBI
Rnor_6.0	1	214,249,388 - 214,252,455 (-)	NCBI
Rnor_5.0	1	221,166,926 - 221,170,447 (-)	NCBI
RGSC_v3.4	1	201,456,689 - 201,459,756 (-)	RGD
Celera	1	194,001,244 - 194,004,312 (-)	RGD

Sequence:

show sequence

CAGGGTCCAGCCTGTGACAGCCCATCCAGGCCCGGACGCTGGATCAACACCTGTGACATCACAT
GTGCGCTCCCGCTGCTACATCTGTAGTCACATCTACAGCCACCTTGGCCTAGGAATCCACACTT
AAATTGGGAACCTAGGTGGCTATAAGTTCTCAAACCTCATCTGTGACCCTCAACACCCTAATAC
CTGGGTCACACTTGTGAAACTTCAATTCCCACCTGTGACCAACAATCCTAACGTTTAAAACATA
TTTATGAAACTTGGTTACACTATCTGTGGCTAAAACCATAAAGACACCCAAGGGACTCTTACCT
TATTTGTAATACTGCCTCAGTGACTGCAAGTCATCAGAGTAGTAGCACCTACTTTCTCCCAGAC
TGCCCGTGTAGAAGGAGCAATGGCCGAAGTGAGGGGGGTCCAGCGAGTGCTGTTCGGAGACTGG
CTCTTGGGTGAGGTCAGTAGTGGCCGGTACGAGGGGCTGCAGTGGCTGAATGAGGCTCACACAG
TCTTCCGTGTGCCCTGGAAGCATTTCAGCCGTAGGGATCTGGATGAAGCTGATGCACAGATCTT
CAAGGCCTGGGCTGTGGCCCGAGGGAGGTGGCCACCTAGTGGAGTTAACTTACCACCCCCAGAG
GCTGAGGCTGCTGAGCGAAGAGGCTGGAAGACCAACTTCCGATGTGCACTCCGCAGCACAGGGC
GCTTTATCTTGCGTCAAGACAACTCAGGGGACCCTGCTGATCCGCACAAGGTGTATGAACTTAG
CCCGGAGCTTGGATCTACAACTGGCCCAGCTCTGGAGAACAGGGAAGAAGTGACCCTCAGCAGT
GCCCTACCCACACAGGGTATGTCCCTAGGATCATTCCTGGCAAGAGGAAATGCTGGGTTGCAAA
CCCCAAGCCCTCTGCTTTCTGGTGATGCTGGGGACCTCTTGCTTCAGGTTCTGCAATACAGCCA
CCTACTGGACTCTGAGTCTAGGGCGGACTCAGTCCCACCACAGGCTTCTGGCCAGGAGCAAGAA
CACCTTCCTGAGGAGCCCCATGCAGCATGGCAGATGGAAGCTACCTCCAGCCCCAGGCTTCAAC
ACCCAGTTCTGATGACTGAGCGCAACCTTGGGTCCCTGGATGTGACCATCATGTACAAGGGCCG
CACAGTGCTACAGGCAATGGTGGGGCACCCCAGATGCGTGTTCCTGTATAGCCCCGTGGGCTCA
GCAATAAGAACTTCAGAGCCCCAGCCGGTGATTTTTCCGAGCCCCGCTGAGCTCCCAGATCAGA
AGCAGCTGCACTACACAGAGACTCTCCTACAGCATGTGTCTCCAGGCCTTCAGCTGGAGCTTCG
GGGGCCATCACTATGGGCCCTGCGAATGGGCAAGTGCAAGGTGTACTGGGAGGTGGGCAGCCCT
ATGGGCTCCACCAACCCCTCCACCCCAGCCCAGCTGCTGGAGCGCAACTGCCATACTCCCATCT
TTGACTTCAGCACTTTCTTCCGAGAACTGGAGGAGTTCCGGGCCCGGAGGCGACAAGGATCACC
ACATTACACCATCTACCTGGGTTTTGGGCAAGACTTGTCAGCAGGGAGGCCCAAGGAGAAGAGC
CTGATCCTGGTGAAGCTGGAGCCATGGCTGTGCAAGACACATCTGGAAGGCGTGCAGCGTGAGG
GTGTGTCCTCTCTGGACAGCAGCAGTCTTGGCCTGTGCTTGTCTAGCACCAATAGTCTCTACGA
TGACATTGAACACTTCCTCATGGACCTGGGTCAGTGGGCTTGATTCAGAACCCCAACTTCCAAT
AGAGTTCAGAACCACTGCTGCCCTGGCTCAGGCTTATTCCTTGGCTATATGTCATCTCTAGTGG
ACCTTGTGGAGTCCCTTGAAAGAAGGTGACCCCCCACTCCCTACACACTAGGCCTCCTTTGTAG
CACTCATCTTTACAATAAAGAATTGGTTGGGTTACCATAAAAAAAAAAAAAAAAAAAAAAAAAA
A

hide sequence

RefSeq Acc Id:

XM_006230540 ⟹ XP_006230602

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	1	196,367,380 - 196,370,943 (-)	NCBI
Rnor_6.0	1	214,249,388 - 214,252,909 (-)	NCBI
Rnor_5.0	1	221,166,926 - 221,170,447 (-)	NCBI

Sequence:

show sequence

CACACCCTGCAGCATTCCACCCCGCCCCTGACCGAAGTACTATAAAAGCACGGCTACCTCCTTC
TCACTGAGATAAAACCGTCCCGGCGGCTCCGGTACCAGGGTCCAGCCTGTGACAGCCCATCCAG
GCCCGGACGCTGGATCAACACCTGTGACATCACATGTGCGCTCCCGCTGCTACATCTGTAGTCA
CATCTACAGCCACCTTGGCCTAGGAATCCACACTTAAATTGGGAACCTAGGTGGCTATAAGTTC
TCAAACCTCATCTGTGACCCTCAACACCCTAATACCTGGGTCACACTTGTGAAACTTCAATTCC
CACCTGTGACCAACAATCCTAACGTTTAAAACATATTTATGAAACTTGGTTACACTATCTGTGG
CTAAAACCATAAAGACACCCAAGGGACTCTTACCTTATTTGTAATACTGCCTCAGTGACTGCAA
GTCATCAGAGTAGTAGCACCTACTTTCTCCCAGACTGCCCGTGTAGAAGGAGCAATGGCCGAAG
TGAGGGGGGTCCAGCGAGTGCTGTTCGGAGACTGGCTCTTGGGTGAGGTCAGTAGTGGCCGGTA
CGAGGGGCTGCAGTGGCTGAATGAGGCTCACACAGTCTTCCGTGTGCCCTGGAAGCATTTCAGC
CGTAGGGATCTGGATGAAGCTGATGCACAGATCTTCAAGGCCTGGGCTGTGGCCCGAGGGAGGT
GGCCACCTAGTGGAGTTAACTTACCACCCCCAGAGGCTGAGGCTGCTGAGCGAAGAGGCTGGAA
GACCAACTTCCGATGTGCACTCCGCAGCACAGGGCGCTTTATCTTGCGTCAAGACAACTCAGGG
GACCCTGCTGATCCGCACAAGGTGTATGAACTTAGCCCGGAGCTTGGATCTACAACTGGCCCAG
CTCTGGAGAACAGGGAAGAAGTGACCCTCAGCAGTGCCCTACCCACACAGGGTATGTCCCTAGG
ATCATTCCTGGCAAGAGGAAATGCTGGGTTGCAAACCCCAAGCCCTCTGCTTTCTGGTGATGCT
GGGGACCTCTTGCTTCAGGTTCTGCAATACAGCCACCTACTGGACTCTGAGTCTAGGGCGGACT
CAGTCCCACCACAGGCTTCTGGCCAGGAGCAAGAACACCTTCCTGAGGAGCCCCATGCAGCATG
GCAGATGGAAGCTACCTCCAGCCCCAGGCTTCAACACCCAGTTCTGATGACTGAGCGCAACCTT
GGGTCCCTGGATGTGACCATCATGTACAAGGGCCGCACAGTGCTACAGGCAATGGTGGGGCACC
CCAGATGCGTGTTCCTGTATAGCCCCGTGGGCTCAGCAATAAGAACTTCAGAGCCCCAGCCGGT
GATTTTTCCGAGCCCCGCTGAGCTCCCAGATCAGAAGCAGCTGCACTACACAGAGACTCTCCTA
CAGCATGTGTCTCCAGGCCTTCAGCTGGAGCTTCGGGGGCCATCACTATGGGCCCTGCGAATGG
GCAAGTGCAAGGTGTACTGGGAGGTGGGCAGCCCTATGGGCTCCACCAACCCCTCCACCCCAGC
CCAGCTGCTGGAGCGCAACTGCCATACTCCCATCTTTGACTTCAGCACTTTCTTCCGAGAACTG
GAGGAGTTCCGGGCCCGGAGGCGACAAGGATCACCACATTACACCATCTACCTGGGTTTTGGGC
AAGACTTGTCAGCAGGGAGGCCCAAGGAGAAGAGCCTGATCCTGGTGAAGCTGGAGCCATGGCT
GTGCAAGACACATCTGGAAGGCGTGCAGCGTGAGGGTGTGTCCTCTCTGGACAGCAGCAGTCTT
GGCCTGTGCTTGTCTAGCACCAATAGTCTCTACGATGACATTGAACACTTCCTCATGGACCTGG
GTCAGTGGGCTTGATTCAGAACCCCAACTTCCAATAGAGTTCAGAACCACTGCTGCCCTGGCTC
AGGCTTATTCCTTGGCTATATGTCATCTCTAGTGGACCTTGTGGAGTCCCTTGAAAGAAGGTGA
CCCCCCACTCCCTACACACTAGGCCTCCTTTGTAGCACTCATCTTTACAATAAAGAATTGGTTG
GGTTACCATA

hide sequence

RefSeq Acc Id:

XM_006230541 ⟹ XP_006230603

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	1	196,367,380 - 196,370,943 (-)	NCBI
Rnor_6.0	1	214,249,388 - 214,252,909 (-)	NCBI
Rnor_5.0	1	221,166,926 - 221,170,447 (-)	NCBI

Sequence:

show sequence

CACACCCTGCAGCATTCCACCCCGCCCCTGACCGAAGTACTATAAAAGCACGGCTACCTCCTTC
TCACTGAGATAAAACCGTCCCGGCGGCTCCGGTACCAGGGTCCAGCCTGTGACAGCCCATCCAG
GCCCGGACGCTGGATCAACACCTGTGACATCACATGTGCGCTCCCGCTGCTACATCTGTAGTCA
CATCTACAGCCACCTTGGCCTAGGAATCCACACTTAAATTGGGAACCTAGGTGGCTATAAGTTC
TCAAACCTCATCTGTGACCCTCAACACCCTAATACCTGGGTCACACTTGTGAAACTTCAATTCC
CACCTGTGACCAACAATCCTAACGTTTAAAACATATTTATGAAACTTGGTTACACTATCTGTGG
CTAAAACCATAAAGACACCCAAGGGACTCTTACCTTATTTGTAATACTGCCTCAGTGACTGCAA
GTCATCAGAGTAGTAGCACCTACTTTCTCCCAGACTGCCCGTGTAGAAGGAGCAATGGCCGAAG
TGAGGGGGGTCCAGCGAGTGCTGTTCGGAGACTGGCTCTTGGGTGAGGTCAGTAGTGGCCGGTA
CGAGGGGCTGCAGTGGCTGAATGAGGCTCACACAGTCTTCCGTGTGCCCTGGAAGCATTTCAGC
CGTAGGGATCTGGATGAAGCTGATGCACAGATCTTCAAGGCCTGGGCTGTGGCCCGAGGGAGGT
GGCCACCTAGTGGAGTTAACTTACCACCCCCAGAGGCTGAGGCTGCTGAGCGAAGAGGCTGGAA
GACCAACTTCCGATGTGCACTCCGCAGCACAGGGCGCTTTATCTTGCGTCAAGACAACTCAGGG
GACCCTGCTGATCCGCACAAGGTGTATGAACTTAGCCCGGAGCTTGGATCTACAACTGGCCCAG
CTCTGGAGAACAGGGAAGAAGTGACCCTCAGCAGTGCCCTACCCACACAGGTTCTGCAATACAG
CCACCTACTGGACTCTGAGTCTAGGGCGGACTCAGTCCCACCACAGGCTTCTGGCCAGGAGCAA
GAACACCTTCCTGAGGAGCCCCATGCAGCATGGCAGATGGAAGCTACCTCCAGCCCCAGGCTTC
AACACCCAGTTCTGATGACTGAGCGCAACCTTGGGTCCCTGGATGTGACCATCATGTACAAGGG
CCGCACAGTGCTACAGGCAATGGTGGGGCACCCCAGATGCGTGTTCCTGTATAGCCCCGTGGGC
TCAGCAATAAGAACTTCAGAGCCCCAGCCGGTGATTTTTCCGAGCCCCGCTGAGCTCCCAGATC
AGAAGCAGCTGCACTACACAGAGACTCTCCTACAGCATGTGTCTCCAGGCCTTCAGCTGGAGCT
TCGGGGGCCATCACTATGGGCCCTGCGAATGGGCAAGTGCAAGGTGTACTGGGAGGTGGGCAGC
CCTATGGGCTCCACCAACCCCTCCACCCCAGCCCAGCTGCTGGAGCGCAACTGCCATACTCCCA
TCTTTGACTTCAGCACTTTCTTCCGAGAACTGGAGGAGTTCCGGGCCCGGAGGCGACAAGGATC
ACCACATTACACCATCTACCTGGGTTTTGGGCAAGACTTGTCAGCAGGGAGGCCCAAGGAGAAG
AGCCTGATCCTGGTGAAGCTGGAGCCATGGCTGTGCAAGACACATCTGGAAGGCGTGCAGCGTG
AGGGTGTGTCCTCTCTGGACAGCAGCAGTCTTGGCCTGTGCTTGTCTAGCACCAATAGTCTCTA
CGATGACATTGAACACTTCCTCATGGACCTGGGTCAGTGGGCTTGATTCAGAACCCCAACTTCC
AATAGAGTTCAGAACCACTGCTGCCCTGGCTCAGGCTTATTCCTTGGCTATATGTCATCTCTAG
TGGACCTTGTGGAGTCCCTTGAAAGAAGGTGACCCCCCACTCCCTACACACTAGGCCTCCTTTG
TAGCACTCATCTTTACAATAAAGAATTGGTTGGGTTACCATA

hide sequence

RefSeq Acc Id:

XM_039107968 ⟹ XP_038963896

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	1	196,367,380 - 196,370,162 (-)	NCBI

Protein Sequences


Protein RefSeqs	NP_001028863	(Get FASTA)	NCBI Sequence Viewer
	XP_006230602	(Get FASTA)	NCBI Sequence Viewer
	XP_006230603	(Get FASTA)	NCBI Sequence Viewer
	XP_038963896	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAI04687	(Get FASTA)	NCBI Sequence Viewer
	EDM12004	(Get FASTA)	NCBI Sequence Viewer
	EDM12005	(Get FASTA)	NCBI Sequence Viewer
	EDM12006	(Get FASTA)	NCBI Sequence Viewer
	EDM12007	(Get FASTA)	NCBI Sequence Viewer
	EDM12008	(Get FASTA)	NCBI Sequence Viewer
	EDM12009	(Get FASTA)	NCBI Sequence Viewer
	EDM12010	(Get FASTA)	NCBI Sequence Viewer
	EDM12011	(Get FASTA)	NCBI Sequence Viewer

Reference Sequences

RefSeq Acc Id:

NP_001028863 ⟸ NM_001033691

- UniProtKB:

Q3SWU2 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MAEVRGVQRVLFGDWLLGEVSSGRYEGLQWLNEAHTVFRVPWKHFSRRDLDEADAQIFKAWAVA
RGRWPPSGVNLPPPEAEAAERRGWKTNFRCALRSTGRFILRQDNSGDPADPHKVYELSPELGST
TGPALENREEVTLSSALPTQGMSLGSFLARGNAGLQTPSPLLSGDAGDLLLQVLQYSHLLDSES
RADSVPPQASGQEQEHLPEEPHAAWQMEATSSPRLQHPVLMTERNLGSLDVTIMYKGRTVLQAM
VGHPRCVFLYSPVGSAIRTSEPQPVIFPSPAELPDQKQLHYTETLLQHVSPGLQLELRGPSLWA
LRMGKCKVYWEVGSPMGSTNPSTPAQLLERNCHTPIFDFSTFFRELEEFRARRRQGSPHYTIYL
GFGQDLSAGRPKEKSLILVKLEPWLCKTHLEGVQREGVSSLDSSSLGLCLSSTNSLYDDIEHFL
MDLGQWA

hide sequence

RefSeq Acc Id:

XP_006230603 ⟸ XM_006230541

- Peptide Label:

isoform X2

- Sequence:

show sequence

MAEVRGVQRVLFGDWLLGEVSSGRYEGLQWLNEAHTVFRVPWKHFSRRDLDEADAQIFKAWAVA
RGRWPPSGVNLPPPEAEAAERRGWKTNFRCALRSTGRFILRQDNSGDPADPHKVYELSPELGST
TGPALENREEVTLSSALPTQVLQYSHLLDSESRADSVPPQASGQEQEHLPEEPHAAWQMEATSS
PRLQHPVLMTERNLGSLDVTIMYKGRTVLQAMVGHPRCVFLYSPVGSAIRTSEPQPVIFPSPAE
LPDQKQLHYTETLLQHVSPGLQLELRGPSLWALRMGKCKVYWEVGSPMGSTNPSTPAQLLERNC
HTPIFDFSTFFRELEEFRARRRQGSPHYTIYLGFGQDLSAGRPKEKSLILVKLEPWLCKTHLEG
VQREGVSSLDSSSLGLCLSSTNSLYDDIEHFLMDLGQWA

hide sequence

RefSeq Acc Id:	XP_006230602 ⟸ XM_006230540
- Peptide Label:	isoform X1
- UniProtKB:	Q3SWU2 (UniProtKB/TrEMBL)
- Sequence:	show sequence MAEVRGVQRVLFGDWLLGEVSSGRYEGLQWLNEAHTVFRVPWKHFSRRDLDEADAQIFKAWAVA RGRWPPSGVNLPPPEAEAAERRGWKTNFRCALRSTGRFILRQDNSGDPADPHKVYELSPELGST TGPALENREEVTLSSALPTQGMSLGSFLARGNAGLQTPSPLLSGDAGDLLLQVLQYSHLLDSES RADSVPPQASGQEQEHLPEEPHAAWQMEATSSPRLQHPVLMTERNLGSLDVTIMYKGRTVLQAM VGHPRCVFLYSPVGSAIRTSEPQPVIFPSPAELPDQKQLHYTETLLQHVSPGLQLELRGPSLWA LRMGKCKVYWEVGSPMGSTNPSTPAQLLERNCHTPIFDFSTFFRELEEFRARRRQGSPHYTIYL GFGQDLSAGRPKEKSLILVKLEPWLCKTHLEGVQREGVSSLDSSSLGLCLSSTNSLYDDIEHFL MDLGQWA hide sequence

RefSeq Acc Id:

ENSRNOP00000023504 ⟸ ENSRNOT00000023504

RefSeq Acc Id:	XP_038963896 ⟸ XM_039107968
- Peptide Label:	isoform X3

Protein Domains

IRF tryptophan pentad repeat

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Strain Variation

Strain Sequence Variants (Rnor 6.0)

ACI/EurMcwi (MCW)

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Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Medical College of Wisconsin
Description:	Provided by the Medical College of Wisconsin (Dr. Howard Jacob)

ACI/EurMcwi (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

ACI/N (MCW)

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Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

BBDP/Wor (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

BN/SsN (MCW)

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Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

Buf/N (MCW)

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Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

COP/CrCrl (MCW & UW)

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Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob) University of Wisconsin (Dr. James Shull)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Charles River Laboratories
Description:	Provided by the Medical College of Wisconsin (Dr. Howard Jacob) and UW Madison (Dr. James Shull)

F344/NCrl (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

F344/NRrrc (MCW)

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Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

FHH/EurMcwi (MCW)

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Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Medical College of Wisconsin
Description:	Provided by the Medical College of Wisconsin (Dr. Howard Jacob)

FHH/EurMcwi (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

FHL/EurMcwi (MCW)

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Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Medical College of Wisconsin
Description:	Provided by the Medical College of Wisconsin (Dr. Howard Jacob)

FHL/EurMcwi (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

GH/OmrMcwi (MCW)

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Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Medical College of Wisconsin
Description:	Provided by the Medical College of Wisconsin (Dr. Howard Jacob)

GK/Ox (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

LE/Stm (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

LEW/Crl (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

LEW/NCrlBR (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

LH/MavRrrc (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

LL/MavRrrc (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

LN/MavRrrc (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

M520/N (MCW)

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Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

MHS/Gib (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

MNS/Gib (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

MR/N (MCW)

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Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

SBH/Ygl (MCW)

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Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Medical College of Wisconsin
Description:	SBH/Ygl sequenced by MCW

SBH/Ygl (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

SBN/Ygl (MCW)

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Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Medical College of Wisconsin
Description:	SBN/Ygl sequenced by MCW

SBN/Ygl (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

SHR/NHsd (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

SHRSP/Gcrc (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

SR/JrHsd (MCW)

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Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Harlan Laboratories
Description:	Provided by the Medical College of Wisconsin (Dr. Howard Jacob)

SR/JrHsd (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

SS/Jr (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

SS/JrHsdMcwi (MCW)

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Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Medical College of Wisconsin
Description:	Provided by the Medical College of Wisconsin (Dr. Howard Jacob)

SS/JrHsdMcwi (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

WAG/Rij (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

WKY/Gcrc (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

WKY/N (MCW)

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Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

WKY/NCrl (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

WKY/NHsd (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

WN/N (MCW)

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Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1307828	AgrOrtholog
Ensembl Genes	ENSRNOG00000017414	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein	ENSRNOP00000023504	ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000023504	ENTREZGENE, UniProtKB/TrEMBL
Gene3D-CATH	1.10.10.10	UniProtKB/TrEMBL
	2.60.200.10	UniProtKB/TrEMBL
IMAGE_CLONE	IMAGE:7442863	IMAGE-MGC_LOAD
InterPro	Interferon_regulatory_fac_CS	UniProtKB/TrEMBL
	Interferon_regulatory_factor	UniProtKB/TrEMBL
	Interferon_regulatory_factor-3	UniProtKB/TrEMBL
	SMAD_dom-like	UniProtKB/TrEMBL
	SMAD_FHA_domain	UniProtKB/TrEMBL
	WH-like_DNA-bd_sf	UniProtKB/TrEMBL
	WH_DNA-bd_sf	UniProtKB/TrEMBL
KEGG Report	rno:293624	UniProtKB/TrEMBL
MGC_CLONE	MGC:125013	IMAGE-MGC_LOAD
NCBI Gene	293624	ENTREZGENE
PANTHER	PTHR11949	UniProtKB/TrEMBL
Pfam	IRF	UniProtKB/TrEMBL
	IRF-3	UniProtKB/TrEMBL
PhenoGen	Irf7	PhenoGen
PRINTS	INTFRNREGFCT	UniProtKB/TrEMBL
PROSITE	IRF	UniProtKB/TrEMBL
	IRF_2	UniProtKB/TrEMBL
SMART	IRF	UniProtKB/TrEMBL
	IRF-3	UniProtKB/TrEMBL
Superfamily-SCOP	SMAD_FHA	UniProtKB/TrEMBL
	SSF46785	UniProtKB/TrEMBL
UniProt	F7FGY2_RAT	UniProtKB/TrEMBL
	Q3SWU2	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2005-12-06	Irf7	interferon regulatory factor 7	Irf7_predicted	interferon regulatory factor 7 (predicted)	Symbol and Name updated	1559027	APPROVED
2005-01-12	Irf7_predicted	interferon regulatory factor 7 (predicted)			Symbol and Name status set to approved	70820	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Disease Annotations - OMIM

Imported Annotations - KEGG (archival)