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Gene: Mki67 (marker of proliferation Ki-67) Rattus norvegicus
Symbol: Mki67
Name: marker of proliferation Ki-67
RGD ID: 1305476
Description: Predicted to have protein C-terminus binding activity. Involved in several processes, including animal organ regeneration; cellular response to heat; and hyaluronan metabolic process. Localizes to nucleus. Used to study leiomyoma; malignant glioma; and prostate carcinoma. Biomarker of kidney disease; mucositis; type 2 diabetes mellitus; and urinary bladder cancer. Human ortholog(s) of this gene implicated in Crohn's disease; breast cancer; human immunodeficiency virus infectious disease; and pancreatic cancer. Orthologous to human MKI67 (marker of proliferation Ki-67); INTERACTS WITH (+)-alpha-tocopherol; (-)-cotinine; (S)-nicotine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: antigen identified by monoclonal antibody Ki-67; antigen KI-67; LOC291234
Homo sapiens (human) : MKI67 (marker of proliferation Ki-67)  HGNC  Alliance
Mus musculus (house mouse) : Mki67 (antigen identified by monoclonal antibody Ki 67)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Mki67 (marker of proliferation Ki-67)
Pan paniscus (bonobo/pygmy chimpanzee) : MKI67 (marker of proliferation Ki-67)
Canis lupus familiaris (dog) : MKI67 (marker of proliferation Ki-67)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Mki67 (marker of proliferation Ki-67)
Sus scrofa (pig) : MKI67 (marker of proliferation Ki-67)
Chlorocebus sabaeus (African green monkey) : MKI67 (marker of proliferation Ki-67)
Heterocephalus glaber (naked mole-rat) : Mki67 (marker of proliferation Ki-67)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.01207,993,895 - 208,020,454 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1207,993,895 - 208,020,454 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01214,925,922 - 214,952,481 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41195,310,027 - 195,336,224 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11195,460,292 - 195,486,216 (-)NCBI
Celera1188,211,009 - 188,236,363 (-)NCBICelera
Cytogenetic Map1q41NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
More on Mki67
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1305476
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2020-08-20
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.