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Gene: Pnpla2 (patatin-like phospholipase domain containing 2) Rattus norvegicus
Symbol: Pnpla2
Name: patatin-like phospholipase domain containing 2
Description: Predicted to have retinyl-palmitate esterase activity and triglyceride lipase activity. Predicted to be involved in several processes, including acylglycerol metabolic process; negative regulation of sequestering of triglyceride; and positive regulation of triglyceride catabolic process. Predicted to localize to several cellular components, including cytosol; lipid droplet; and nucleoplasm. Orthologous to human PNPLA2 (patatin like phospholipase domain containing 2); INTERACTS WITH (+)-catechin; (-)-cotinine; (S)-nicotine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: adipose triglyceride lipase; LOC361676; patatin-like phospholipase domain-containing protein 2; RGD1309044; similar to RIKEN cDNA 0610039C21
Homo sapiens (human) : PNPLA2 (patatin like phospholipase domain containing 2)  HGNC  Alliance
Mus musculus (house mouse) : Pnpla2 (patatin-like phospholipase domain containing 2)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Pnpla2 (patatin like phospholipase domain containing 2)
Pan paniscus (bonobo/pygmy chimpanzee) : PNPLA2 (patatin like phospholipase domain containing 2)
Canis lupus familiaris (dog) : PNPLA2 (patatin like phospholipase domain containing 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Pnpla2 (patatin like phospholipase domain containing 2)
Sus scrofa (pig) : PNPLA2 (patatin like phospholipase domain containing 2)
Chlorocebus sabaeus (African green monkey) : PNPLA2 (patatin like phospholipase domain containing 2)
Heterocephalus glaber (naked mole-rat) : Pnpla2 (patatin like phospholipase domain containing 2)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.01214,434,638 - 214,439,720 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1214,434,626 - 214,439,720 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01220,914,961 - 220,920,043 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41201,641,939 - 201,647,021 (+)NCBIRGSC3.4rn4RGSC3.4
Celera1194,186,305 - 194,191,301 (+)NCBICelera
Cytogenetic Map1q41NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
More on Pnpla2
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1309044
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2020-06-09
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.