Predicted to enable acylglycerol O-acyltransferase activity and carboxylic ester hydrolase activity. Predicted to be involved in several processes, including acylglycerol metabolic process; intracellular triglyceride homeostasis; and lipid droplet disassembly. Predicted to act upstream of with a negative effect on lipid droplet fusion. Predicted to act upstream of or within lipid droplet organization. Predicted to be located in cytosol; nucleoplasm; and plasma membrane. Predicted to be active in cytoplasm; lipid droplet; and membrane. Orthologous to human PNPLA2 (patatin like phospholipase domain containing 2); INTERACTS WITH (+)-catechin; (-)-cotinine; (S)-nicotine.
[Nicotine results in increased abundance of Cotinine] which results in increased expression of PNPLA2 mRNA and [Nicotine results in increased abundance of Cotinine] which results in increased expression of PNPLA2 protein
[Nicotine results in increased abundance of Cotinine] which results in increased expression of PNPLA2 mRNA and [Nicotine results in increased abundance of Cotinine] which results in increased expression of PNPLA2 protein
[Dietary Sucrose co-treated with Dietary Fats co-treated with bisphenol A co-treated with Diethylhexyl Phthalate co-treated with Tetrachlorodibenzodioxin co-treated with 2 more ...
[Dietary Sucrose co-treated with Dietary Fats co-treated with bisphenol A co-treated with Diethylhexyl Phthalate co-treated with Tetrachlorodibenzodioxin co-treated with 2 more ...
[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin] results in increased expression of PNPLA2 mRNA
[Dietary Sucrose co-treated with Dietary Fats co-treated with bisphenol A co-treated with Diethylhexyl Phthalate co-treated with Tetrachlorodibenzodioxin co-treated with 2 more ...
[Dietary Sucrose co-treated with Dietary Fats co-treated with bisphenol A co-treated with Diethylhexyl Phthalate co-treated with Tetrachlorodibenzodioxin co-treated with 2 more ...
[MT1 gene mutant form results in increased susceptibility to Cadmium Chloride] which results in decreased expression of PNPLA2 mRNA and [MT2 gene mutant form results in increased susceptibility to Cadmium Chloride] which results in decreased expression of PNPLA2 mRNA
[Clofibrate co-treated with Acetaminophen] affects the expression of PNPLA2 mRNA and PPARA affects the reaction [[Clofibrate co-treated with Acetaminophen] affects the expression of PNPLA2 mRNA]
[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin] results in increased expression of PNPLA2 mRNA
Scopoletin inhibits the reaction [Ethanol results in increased expression of PNPLA2 mRNA] and Silymarin inhibits the reaction [Ethanol results in increased expression of PNPLA2 mRNA]
bisphenol A promotes the reaction [Fructose results in decreased expression of PNPLA2 mRNA] and Fructose promotes the reaction [bisphenol A results in decreased expression of PNPLA2 mRNA]
[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin] results in increased expression of PNPLA2 mRNA
[licarin A affects the susceptibility to [INS protein co-treated with 1-Methyl-3-isobutylxanthine co-treated with Dexamethasone]] which results in increased expression of PNPLA2 mRNA more ...
N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [[licarin A affects the susceptibility to [INS protein co-treated with 1-Methyl-3-isobutylxanthine co-treated with Dexamethasone]] which results in increased expression of PNPLA2 protein]
[Nicotine results in increased abundance of Cotinine] which results in increased expression of PNPLA2 mRNA and [Nicotine results in increased abundance of Cotinine] which results in increased expression of PNPLA2 protein
pirinixic acid inhibits the reaction [1 and 3-dichloro-2-propanol results in decreased expression of and results in decreased localization of PNPLA2 protein]
PNPLA2 protein promotes the reaction [resveratrol results in decreased expression of IL6 mRNA] and PNPLA2 protein promotes the reaction [resveratrol results in decreased expression of TNF mRNA]
salvianolic acid A affects the reaction [[Streptozocin co-treated with [APOE protein affects the susceptibility to Dietary Fats]] affects the expression of PNPLA2 protein]
[Streptozocin co-treated with [APOE protein affects the susceptibility to Dietary Fats]] affects the expression of PNPLA2 protein and salvianolic acid A affects the reaction [[Streptozocin co-treated with [APOE protein affects the susceptibility to Dietary Fats]] affects the expression of PNPLA2 protein]