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Gene: Itgam (integrin subunit alpha M) Rattus norvegicus
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Symbol: Itgam
Name: integrin subunit alpha M
Description: Predicted to have anion binding activity; heat shock protein binding activity; and opsonin binding activity. Predicted to be involved in several processes, including activated T cell proliferation; leukocyte migration; and microglia development. Predicted to localize to several cellular components, including the external side of plasma membrane; extracellular space; and plasma membrane raft. Human ortholog(s) of this gene implicated in lupus nephritis. Orthologous to human ITGAM (integrin subunit alpha M); PARTICIPATES IN integrin mediated signaling pathway; Entamoebiasis pathway; Leishmaniasis pathway; INTERACTS WITH 1-naphthyl isothiocyanate; 17beta-estradiol; acrylamide.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: Cd11b; integrin alpha M; Integrin alpha-M; integrin, alpha M
Orthologs:
Homo sapiens (human) : ITGAM (integrin subunit alpha M)  HGNC  Alliance
Mus musculus (house mouse) : Itgam (integrin alpha M)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Itgam (integrin subunit alpha M)
Pan paniscus (bonobo/pygmy chimpanzee) : ITGAM (integrin subunit alpha M)
Canis lupus familiaris (dog) : ITGAM (integrin subunit alpha M)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Itgam (integrin subunit alpha M)
Chlorocebus sabaeus (African green monkey) : ITGAM (integrin subunit alpha M)
Heterocephalus glaber (naked mole-rat) : Itgam (integrin subunit alpha M)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01199,495,312 - 199,545,738 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1199,495,298 - 199,623,960 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01206,522,794 - 206,573,619 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41187,334,413 - 187,385,583 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11187,484,293 - 187,535,464 (+)NCBI
Celera1180,308,890 - 180,355,319 (+)NCBICelera
Cytogenetic Map1q37NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 6.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
 
More on Itgam
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 2926
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2020-03-04
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.