Gene: ITGAM (integrin subunit alpha M) Chlorocebus sabaeus

Analyze

Symbol:

ITGAM

Name:

integrin subunit alpha M

RGD ID:

18654062

Description:

ENCODES a protein that exhibits cargo receptor activity (ortholog); complement component C3b binding (ortholog); heparan sulfate proteoglycan binding (ortholog); INVOLVED IN activated T cell proliferation (ortholog); amyloid-beta clearance (ortholog); cell adhesion (ortholog); PARTICIPATES IN integrin mediated signaling pathway; ASSOCIATED WITH abdominal aortic aneurysm (ortholog); Acute Lung Injury (ortholog); acute myeloid leukemia (ortholog); FOUND IN cell surface (ortholog); membrane raft (ortholog); nucleus (ortholog)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

integrin alpha-M

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	ITGAM (integrin subunit alpha M)	NCBI	Ortholog
Mus musculus (house mouse):	Itgam (integrin alpha M)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus norvegicus (Norway rat):	Itgam (integrin subunit alpha M)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Itgam (integrin subunit alpha M)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	ITGAM (integrin subunit alpha M)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	ITGAM (integrin subunit alpha M)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Itgam (integrin subunit alpha M)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	ITGAM (integrin subunit alpha M)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Itgam (integrin subunit alpha M)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline

Latest Assembly:

ChlSab1.1 - Green Monkey 1.1 Assembly

Position:

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mChlSab1.0.hap1	5	28,281,673 - 28,361,539 (+)	NCBI		mChlSab1.0.hap1
Vero_WHO_p1.0	NW_023666068	1,400,356 - 1,493,976 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0
ChlSab1.1	5	27,957,162 - 28,042,697 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	5	27,957,324 - 28,042,691 (+)	Ensembl		ChlSab1.1 Ensembl	chlSab2	Vervet-AGM

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

abdominal aortic aneurysm (ISO)

Acute Lung Injury (ISO)

acute myeloid leukemia (ISO)

acute myocardial infarction (ISO)

acute promyelocytic leukemia (ISO)

allergic contact dermatitis (ISO)

Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis (ISO)

anxiety disorder (ISO)

asthma (ISO)

atherosclerosis (ISO)

atrial fibrillation (ISO)

Behcet's disease (ISO)

Brain Death (ISO)

brain ischemia (ISO)

Breast Cancer, Familial (ISO)

Burns (ISO)

cerebral infarction (ISO)

cholangiocarcinoma (ISO)

clear cell renal cell carcinoma (ISO)

colon adenocarcinoma (ISO)

Coronary Disease (ISO)

diabetic angiopathy (ISO)

Diabetic Foot (ISO)

diabetic retinopathy (ISO)

disease by infectious agent (ISO)

esophageal cancer (ISO)

Experimental Diabetes Mellitus (ISO)

familial hyperlipidemia (ISO)

glomerulonephritis (ISO)

goiter (ISO)

Hypercholesterolemia (ISO)

hyperglycemia (ISO)

hyperinsulinism (ISO)

hyperthyroidism (ISO)

ileitis (ISO)

Insulin Resistance (ISO)

intermediate coronary syndrome (ISO)

Invasive Candidiasis (ISO)

limb ischemia (ISO)

Liver Reperfusion Injury (ISO)

Lung Injury (ISO)

lung squamous cell carcinoma (ISO)

lupus nephritis (ISO)

Lupus Vasculitis, Central Nervous System (ISO)

Memory Disorders (ISO)

mesangial proliferative glomerulonephritis (ISO)

myocardial infarction (ISO)

myopia (ISO)

nephritis (ISO)

Nerve Degeneration (ISO)

Neuralgia (ISO)

neutropenia (ISO)

obesity (ISO)

ovarian serous cystadenocarcinoma (ISO)

peritonitis (ISO)

persistent fetal circulation syndrome (ISO)

pre-eclampsia (ISO)

respiratory failure (ISO)

rheumatoid arthritis (ISO)

Sepsis (ISO)

Skeletal Muscle Reperfusion Injury (ISO)

Spinal Cord Compression (ISO)

stomach cancer (ISO)

stroke (ISO)

systemic lupus erythematosus (ISO)

thrombosis (ISO)

thymoma (ISO)

Thyroid Carcinoma, Nonmedullary 1 (ISO)

transient cerebral ischemia (ISO)

type 2 diabetes mellitus (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

activated T cell proliferation (ISO)

amyloid-beta clearance (ISO)

cell adhesion (IEA,ISO)

cell adhesion mediated by integrin (IEA)

cell-cell adhesion (IEA,ISO)

cell-cell adhesion mediated by integrin (IEA)

cell-matrix adhesion (IEA)

cellular extravasation (ISO)

complement receptor mediated signaling pathway (ISO)

complement-mediated synapse pruning (ISO)

ectodermal cell differentiation (IEA)

forebrain development (ISO)

heterotypic cell-cell adhesion (ISO)

integrin-mediated signaling pathway (IEA)

leukocyte adhesion to vascular endothelial cell (IEA)

leukocyte cell-cell adhesion (ISO)

leukocyte migration involved in inflammatory response (ISO)

microglia development (ISO)

microglial cell activation (ISO)

negative regulation of dopamine metabolic process (ISO)

neutrophil apoptotic process (ISO)

neutrophil chemotaxis (ISO)

phagocytosis (ISO)

phagocytosis, engulfment (ISO)

positive regulation of mast cell differentiation (ISO)

positive regulation of microglial cell mediated cytotoxicity (ISO)

positive regulation of neutrophil degranulation (IEA)

positive regulation of protein targeting to membrane (ISO)

positive regulation of superoxide anion generation (IEA)

receptor-mediated endocytosis (ISO)

response to amphetamine (ISO)

response to curcumin (ISO)

response to estradiol (ISO)

response to Gram-positive bacterium (ISO)

response to ischemia (ISO)

response to mechanical stimulus (ISO)

vertebrate eye-specific patterning (ISO)

Cellular Component

cell surface (IEA,ISO)

external side of plasma membrane (IEA)

extracellular region (IEA)

integrin alphaM-beta2 complex (IEA)

integrin complex (IEA)

membrane (IEA)

membrane raft (ISO)

nucleus (ISO)

plasma membrane (IEA,ISO)

plasma membrane raft (IEA)

Molecular Function

cargo receptor activity (ISO)

cell adhesion receptor activity (IEA)

complement component C3b binding (ISO)

heat shock protein binding (IEA)

heparan sulfate proteoglycan binding (ISO)

heparin binding (ISO)

integrin binding (IEA)

opsonin binding (ISO)

protein-containing complex binding (ISO)

Molecular Pathway Annotations Click to see Annotation Detail View

integrin mediated signaling pathway (ISO)

References

Additional References at PubMed

PMID:22301074	PMID:30032202

Genomics

Comparative Map Data

ITGAM
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mChlSab1.0.hap1	5	28,281,673 - 28,361,539 (+)	NCBI		mChlSab1.0.hap1
Vero_WHO_p1.0	NW_023666068	1,400,356 - 1,493,976 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0
ChlSab1.1	5	27,957,162 - 28,042,697 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	5	27,957,324 - 28,042,691 (+)	Ensembl		ChlSab1.1 Ensembl	chlSab2	Vervet-AGM

ITGAM
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	16	31,259,975 - 31,332,877 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	16	31,259,954 - 31,332,892 (+)	Ensembl		GRCh38.p14 Ensembl	hg38	GRCh38
GRCh37	16	31,271,296 - 31,344,198 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	16	31,178,789 - 31,251,714 (+)	NCBI	Build 36	Build 36	hg18	NCBI36
Build 34	16	31,178,811 - 31,251,691	NCBI
Celera	16	28,953,869 - 29,026,766 (-)	NCBI		Celera
Cytogenetic Map	16	p11.2	NCBI
HuRef	16	28,832,071 - 28,904,704 (+)	NCBI		HuRef
CHM1_1	16	32,589,199 - 32,661,884 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	16	31,647,380 - 31,720,298 (+)	NCBI		T2T-CHM13v2.0

Itgam
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	7	127,661,812 - 127,717,663 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	7	127,661,808 - 127,717,753 (+)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	7	128,062,640 - 128,118,491 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	7	128,062,640 - 128,118,491 (+)	Ensembl		GRCm38.p6 Ensembl	mm10	GRCm38
MGSCv37	7	135,206,154 - 135,262,005 (+)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	7	127,853,854 - 127,908,772 (+)	NCBI		MGSCv36	mm8
Celera	7	127,897,978 - 127,954,099 (+)	NCBI		Celera
Cytogenetic Map	7	F3	NCBI
cM Map	7	69.93	NCBI

Itgam
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	1	192,089,496 - 192,139,947 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	1	192,089,542 - 192,139,943 (+)	Ensembl				GRCr8
mRatBN7.2	1	182,659,047 - 182,709,501 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	1	182,659,000 - 182,709,503 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	1	191,009,691 - 191,059,554 (+)	NCBI	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	1	198,195,778 - 198,245,649 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	1	190,866,175 - 190,916,092 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0
Dahl_SR_JrHsd	1	191,405,241 - 191,449,619 (+)	NCBI
Lyon_Normotensive	1	196,407,414 - 196,451,794 (+)	NCBI
Lyon_Hypertensive	1	193,074,965 - 193,119,348 (+)	NCBI
F344_StmMcwi	1	191,365,191 - 191,409,582 (+)	NCBI
Rnor_6.0	1	199,495,312 - 199,545,738 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	1	199,495,298 - 199,623,960 (+)	Ensembl		Rnor_6.0 Ensembl	rn6	Rnor6.0
Rnor_5.0	1	206,522,794 - 206,573,619 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	1	187,334,413 - 187,385,583 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	1	180,308,890 - 180,355,319 (+)	NCBI		Celera
RGSC_v3.1	1	187,484,293 - 187,535,464 (+)	NCBI
Cytogenetic Map	1	q37	NCBI

Itgam
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955493	8,116,834 - 8,260,759 (+)	Ensembl		ChiLan1.0 Ensembl
ChiLan1.0	NW_004955493	8,116,886 - 8,160,806 (+)	NCBI	ChiLan1.0	ChiLan1.0

ITGAM
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	18	34,467,770 - 34,540,427 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	16	39,269,199 - 39,341,886 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	16	23,634,476 - 23,707,147 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	16	31,630,983 - 31,702,406 (+)	NCBI	PanPan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	16	31,630,146 - 31,702,406 (+)	Ensembl		PanPan1.1 Ensembl	panPan2	panpan1.1

ITGAM
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	6	16,944,062 - 16,996,525 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	6	16,808,971 - 16,996,286 (-)	Ensembl		CanFam3.1 Ensembl	canFam3	CanFam3.1
Dog10K_Boxer_Tasha	6	18,516,000 - 18,571,559 (-)	NCBI	Dog10K_Boxer_Tasha	Dog10K_Boxer_Tasha
ROS_Cfam_1.0	6	17,068,771 - 17,127,224 (-)	NCBI	ROS_Cfam_1.0	ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	6	17,069,907 - 17,127,159 (-)	Ensembl				ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	6	16,871,848 - 16,927,654 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	6	16,791,010 - 16,846,822 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	6	17,102,490 - 17,158,038 (-)	NCBI	UU_Cfam_GSD_1.0	UU_Cfam_GSD_1.0

Itgam
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mIctTri1.hap1	10	123,494,334 - 123,543,879 (-)	NCBI		mIctTri1.hap1
HiC_Itri_2	NW_024409344	125,528,028 - 125,576,877 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936543	8,461,307 - 8,508,524 (-)	Ensembl		SpeTri2.0 Ensembl
SpeTri2.0	NW_004936543	8,460,526 - 8,508,524 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

ITGAM
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	3	17,204,610 - 17,268,018 (-)	Ensembl		Sscrofa11.1 Ensembl	susScr11	Sscrofa11.1
Sscrofa11.1	3	17,216,719 - 17,272,134 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	3	17,651,478 - 17,668,230 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3
Pig Cytomap	3	p	NCBI

Itgam
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla 1.0	NW_004624782	14,316,505 - 14,367,841 (+)	NCBI	HetGla 1.0	HetGla 1.0	hetGla2
HetGla_female_1.0 Ensembl	NW_004624782	14,318,499 - 14,367,922 (+)	Ensembl		HetGla_female_1.0 Ensembl	hetGla2	HetGla_female_1.0 Ensembl
Naked mole-rat maternal Ensembl	23	14,106,230 - 14,166,749 (+)	Ensembl

Variants

Variants in ITGAM
2259 total Variants

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

ectoderm	endocrine system	hemolymphoid system	mesenchyme	mesoderm	nervous system	reproductive system
76	36	20	36	36	60	20

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_007990737	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_007990746	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_007990754	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	JBLKOC010000005	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSCSAT00000003722 ⟹ ENSCSAP00000002002

Type:

CODING

Position:

Green Monkey Assembly	Chr	Position (strand)	Source
ChlSab1.1 Ensembl	5	27,957,324 - 28,042,691 (+)	Ensembl

RefSeq Acc Id:

XM_007990737 ⟹ XP_007988928

Type:

CODING

Position:

Green Monkey Assembly	Chr	Position (strand)	Source
mChlSab1.0.hap1	5	28,281,673 - 28,361,539 (+)	NCBI
Vero_WHO_p1.0	NW_023666068	1,400,356 - 1,493,976 (-)	NCBI
ChlSab1.1	5	27,957,162 - 28,042,674 (+)	NCBI

Sequence:

show sequence

GTGCTCACTGAGCCTCCGCCCTCTTCCTTTCAATCTCCGATAGACTTCTGCCTCCTACTTCTCC
TTTTCTGCCCTTCCTTGCTTTGGCGGCTTCCTTGGGGTTCCTCAGTGGCGCCTGCAACCCCCGG
TTCACCTCCTTCCAGGTTCTGGCTCCTTCCAGCCATGGCTCTCAGAGTCCTTCTGTTAACAGCC
TTGACCTTATGTCATGGGTTCAACCTGGACACTGAAAACGTAATGACCTTCCAAGAGAACGCAA
AGGGCTTCGGGCAGAGCGTGGTCCAGCTTCAGGGATCCAGGGTGGTGGTTGGAGCCCCCCAGGA
GATAGTGGCTGCCAACCAAACGGGCAGCCTCTACCAGTGTGATTACAGCATAGGCTCATGCGAG
CCCATCCGCCTGCAGATCCCCGAGGAGGCTGTGAACATGTCCCTGGGCCTGTCCCTGGCAGCCA
CCACCAGCCCCGCCCAGCTGCTGGCCTGTGGCCCCACCATGCACCAGATTTGCAGTGAGAACAC
GTATGTGAAAGGGCTCTGCTTCCTGTTTGGATCCAACCTACGGCAGCAGCCCCAGAACTTCCCA
GGGACCCTCCGAGGGTGTCCTGAACAGGACATCGTCTTCTTGATTGACGGCTCTGGTAGCATCA
ACCCACGTGAATTTCAGCAGATGAAGGATTTTGTCTCGATCATGATGGAGCAATTAAAAAAGTC
CAAAACCTTGTTCTCTTTGATGCAGTACTCAGAAGAATTCTGGACTCACTTTACCTTCAAAGAG
TTCCAGGGCAACCCTAACCCGAGATCACTGGTGAACTCAATAACGCAGCTGTATGGGCGGACAC
ACACGGCCACGGCCATCCGCAAAGTGGTACGAGAACTGTTTAACGTCAACCAGGGAGCCCGACA
GAATGCCCGTAAGATCCTAGTTGTCATCACAGATGGAGAAAAGTTTGGCGATCCATTGGGATAT
GAGGACGTCATCCCTGAGGCAGACAGAGAGGGAGTCATTCGCTACGTCATTGGGGTGGGAGATG
CCTTCCGCAGTTTGAAATCCCGCCAAGAGCTTAATACCATTGCATCCAAGCCACCTCGTGATCA
CGTGTTCCAGGTGAATAACTTTGAGGCTCTGAAGACCATTCAGAACCAGCTTCAGGAGAAGATC
TTTGCGATCGAGGGTACTCAGACAGGAAGTACCAGCTCCTTTGAGCATGAGATGTCTCAGGAAG
GCTTCAGTGCTGCCATCACATCTAACGGCCCCTTGCTGAGCACTGTGGGGAGCTATGACTGGGC
TGGTGGAGCCTTTCTATATACATCAAACGAGAAAAGCACCTTCATCAACATGACCAGAGTGGAT
TCAGACATGAATGATGCTTACTTGGGTTATGCTGCCACCGTCATCTTGCGGAACCGGGTGCAAA
ACCTGGTTCTGGGGGCACCTCGATATCAGCACATCGGCCTGGTGGCGATGTTCAGGCAGAACGC
TGGCATGTGGGAGTCCAACGCCAATGTCAAGGGCACCCAGATCGGTGCCTACTTCGGGGCCTCC
CTCTGCTCCGTGGATGTGGACAGCAACGGCAGCACTGACCTTGTCCTCATCGGGGCCCCCTATT
ACTATGAGCAGACCCGAGGGGGCCAGGTGTCTGTGTGCCCCTTGCCCAGGGCGCAGAGGGGTCG
GTGGCAGTGTGATGCTGTTCTCTACGGGGAGCAGGGCCAACCCTGGGGCCGCTTTGGGGCAGCC
CTAACAGTGCTGGGGGATGTGAATGGAGACAAGCTGACGGATGTGGCCATTGGGGCCCCAGGAG
AGGAGGACAACCAGGGTGCTGTTTACCTGTTTCATGGAACCTCAGGATTTGGCATCAGCCCCTC
CCATAGCCAGCGGATAGCAGGCTCCAAGCTCCCTCCCAGGCTCCAGTATTTTGGTCAGTCACTG
AGTGGGGGGCAGGACCTCACAATGGATGGACTGGTGGACCTGACTGTAGGAGCCCAGGGGCACG
TGCTGTTGTTCAGGTCCCAGCCAGTACTGAGAGTAGAGGCAACTATGGAGTTCAATCCCAGGGA
AGTGGCAAGGAATGTATTTGAGTGTAATGATCAGACGGTGAAAGGCAAGGAAGCTGGGGAGGTC
AGAGTCTGCCTCCATGTCCAGAAGAGCACACGGGATCGGCTAAGAGAAGGGCAGATCCAGAGTG
TTGTGACTTACGACCTGGCTCTGGACTCCGGCCCCCCACATTCCCGCGCTGTCTTCGGTGAGAC
AAAGAACAGCACGCGCAGGCAGACGAAGACCTTGGGGCTGACCCGGACTTGTGAGACCCTGAAG
CTACAGTTGCCGGATTGCATCGAGGACCCAGTGAGCCCCATTGTGCTGCGTCTGAACTTCTCTC
TGGTGGGAACTCCCTTGTCTGCTTTCGGGAACCTCCGGCCGGTGCTGGCTGAGGATGCTCAGAG
AGTCTTCATAGCCTTATTTCCCTTTGAGAAGAATTGTGGCAATGACAACATTTGCCAGGATGAC
CTCAGCATCACCTTCAGTTTCATGAGCCTGGACTGCCTCGTGGTGGGTGGGCCCCGGGAGTTCA
ACGTGACAGTGACTGTGAGAAATGATGGCGAGGACTCCTACAGGACACAGGTCACCTTCTTCTT
CCCGCTTGGCCTGTCCTACCGGAAGGTGTCCAGGCTCCAGAACCAGCGCTCACAGCGATCCTGG
CGCCTGGCCTGTGAGTCTGCCTCCTCCACCGAAGTGCCTGGGGCCTTGAAGAGCACCAGCTGCA
GCATAAACCACCCCATCTTCCCAGAAAACTCAGAGGTCACCTTTAATATCACATTTGATGTGGA
CTCTAAGGCTTCCCTTGGAAACAAACTGCTCCTCAAGGCCAATGTGACCAGTGAGAACAACATG
TCCAGAACCAACAAAACCGAATTCCAACGGGAGCTGCCGGTGAAATATGCTGTCTACATGGTGG
TCACCAGCCATGAGGTCTCCACTAAATATCTCAACTTCACGGCCTCAGAGAATACCAGTCGGGT
CATGCAGCATCAATATCAGGTCAAAAACCTGGGGCAGAGGAGCCTCCCCATCAGCCTGGTATTC
TTGGTGCCTGTCCGGCTGAACCAGACGATCATATGGGACCGCCCCCAGGTCACTTTCTCCGAGA
GCCTCTCAAGTACGTGCCACACCGAGGAAATATTTCCCACCCCTCACACCGACTTTCTGGCTAA
GCTTCAGAAGGACCCAGTCGTGAACTGCTCCATCGCTGTCTGCCAGAGAATCAAGTGTGACATC
CCGTTCTTTGGCATCCAGGAAGAATTCAATGCCACCCTCAAAGGCAACCTCTCATTTGACTGGT
ACATCAAGACCTCGCATAACCACCTCCTGGTCGTGAGCACAGCTGAGATCATGTTTAACAATTC
CACGTTCACCCTGCTTCCGGGACAGGGGGCGTTTGTGAGGGCCCAGACGGAGACCAAAGTGGAG
CCGTTCGAGGTCCCCAACCCCTTGCCGCTCATCGTGGGCAGCTCTGTGGGGGGGCTGCTGCTCT
TGGCCCTCATCACCGCCGCGCTGTACAAGCTCGGCTTCTTCAAGCGGCAGTACAAGGACATGAT
GAGTGAAGGGGGTCCCCCGGGGGCCGAACCCCAGTAGTGGCTCCTTCCCGACCGACCGAGCTGC
CTCTCCGTGGCCAGCAGGACTCTGCCCAGACCACACGTAGCCCCCAGGCTGCTGGACACACCGG
ACGGCGAAGTCTCCTCGAGACAGGACCAGCTTGGGCTTACATTTGTGTGTGTGCAAGTGTGTAT
GTGCATGTGTGTGAGTGTGTGCAAGTGTCTATGTGCAAGCGTGTGGACATGTGTGCGTGTGTGT
GCACTCACGCGTCCACGTGTGTGTGCAAGTATGTGTGTCCAAGTGTGTGCAAGTGTGTGTAAGC
GTGTGCATGTGTGTGCTCAGGGGTGTATGGCTCATGTGTGTGACTCAGATGTCTCTGGTGTGTG
GGTAGGTGGTGGCAGCGCAGCCTCTCTGGCAGAAGGGAACTGCCTGGGCTCCCTTGTGCGTGGG
TGAAGCCGCTGCTGGGTTTTCCTCCGGGACAGGCAAGGGTCAATCCTGTGGGTGAACACAGAGG
GAAAGGCAGCAGCTCCTCTCCACTGAAGGAAGTGGGACTTCCTGTCGCCGGAGAGCCTGCGGGG
CCTGCGGGAGCCAGCACAGCTTGGATGGAGATTCCGTGAGAAGCCGTGGGTGGAACCAGGAGCC
TCACCAAACCCACTCCACACCAGCGCTGATGCCCAGTAAAGATGTCCACTGAGGAATGATGAAT
CTCCCTTTATGGATTCATTTATTATTTCAATGTGACTTTAATTTTTTCAATGGATAAGCCTGTC
TACGGTACAAAAATCAAAAAGCATTCAAGAGTGTACAGTGAAAAGTCTCCCTTTCCAGATATTC
AAGTCACCTCCTTAAAGGTAGTCACGCTTGTGTTTTGAGGTTTCCTTGAGATTCCAGGCGATGT
GCAAATGTATGCACGTGTGCACACACATACACCACACATACACACACACAAGCTTTTTTACACA
AATGGTAGCATACTTTGTATTGGTCTGTATCTTGCTTTTTTCCACTAATGTTTCTCAGACATCG
GTTCATATTGACATAAATTACTTTTTCATTCTTTTATACCGCTGCATAGTATTCCATTGTGTGA
GTGTACCATAGTGTAATTAACCAGTCTTCTTTTGATATATTATTTTCAATCTCTTGTTATTGCA
TCAATGCTGAGTTAATAAATCAAATATATGTCA

hide sequence

RefSeq Acc Id:

XM_007990746 ⟹ XP_007988937

Type:

CODING

Position:

Green Monkey Assembly	Chr	Position (strand)	Source
mChlSab1.0.hap1	5	28,281,674 - 28,361,539 (+)	NCBI
Vero_WHO_p1.0	NW_023666068	1,400,356 - 1,493,975 (-)	NCBI
ChlSab1.1	5	27,957,163 - 28,042,697 (+)	NCBI

Sequence:

show sequence

TGCTCACTGAGCCTCCGCCCTCTTCCTTTCAATCTCCGATAGACTTCTGCCTCCTACTTCTCCT
TTTCTGCCCTTCCTTGCTTTGGCGGCTTCCTTGGGGTTCCTCAGTGGCGCCTGCAACCCCCGGT
TCACCTCCTTCCAGGTTCTGGCTCCTTCCAGCCATGGCTCTCAGAGTCCTTCTGTTAACAGCCT
TGACCTTATGTCATGGGTTCAACCTGGACACTGAAAACGTAATGACCTTCCAAGAGAACGCAAA
GGGCTTCGGGCAGAGCGTGGTCCAGCTTCAGGGATCCAGGGTGGTGGTTGGAGCCCCCCAGGAG
ATAGTGGCTGCCAACCAAACGGGCAGCCTCTACCAGTGTGATTACAGCATAGGCTCATGCGAGC
CCATCCGCCTGCAGATCCCCGAGGAGGCTGTGAACATGTCCCTGGGCCTGTCCCTGGCAGCCAC
CACCAGCCCCGCCCAGCTGCTGGCCTGTGGCCCCACCATGCACCAGATTTGCAGTGAGAACACG
TATGTGAAAGGGCTCTGCTTCCTGTTTGGATCCAACCTACGGCAGCAGCCCCAGAACTTCCCAG
GGACCCTCCGAGGGTGTCCTGAACAGGACATCGTCTTCTTGATTGACGGCTCTGGTAGCATCAA
CCCACGTGAATTTCAGCAGATGAAGGATTTTGTCTCGATCATGATGGAGCAATTAAAAAAGTCC
AAAACCTTGTTCTCTTTGATGCAGTACTCAGAAGAATTCTGGACTCACTTTACCTTCAAAGAGT
TCCAGGGCAACCCTAACCCGAGATCACTGGTGAACTCAATAACGCAGCTGTATGGGCGGACACA
CACGGCCACGGCCATCCGCAAAGTGGTACGAGAACTGTTTAACGTCAACCAGGGAGCCCGACAG
AATGCCCGTAAGATCCTAGTTGTCATCACAGATGGAGAAAAGTTTGGCGATCCATTGGGATATG
AGGACGTCATCCCTGAGGCAGACAGAGAGGGAGTCATTCGCTACGTCATTGGGGTGGGAGATGC
CTTCCGCAGTTTGAAATCCCGCCAAGAGCTTAATACCATTGCATCCAAGCCACCTCGTGATCAC
GTGTTCCAGGTGAATAACTTTGAGGCTCTGAAGACCATTCAGAACCAGCTTCAGGAGAAGATCT
TTGCGATCGAGGGTACTCAGACAGGAAGTACCAGCTCCTTTGAGCATGAGATGTCTCAGGAAGG
CTTCAGTGCTGCCATCACATCTAACGGCCCCTTGCTGAGCACTGTGGGGAGCTATGACTGGGCT
GGTGGAGCCTTTCTATATACATCAAACGAGAAAAGCACCTTCATCAACATGACCAGAGTGGATT
CAGACATGAATGATGCTTACTTGGGTTATGCTGCCACCGTCATCTTGCGGAACCGGGTGCAAAA
CCTGGTTCTGGGGGCACCTCGATATCAGCACATCGGCCTGGTGGCGATGTTCAGGCAGAACGCT
GGCATGTGGGAGTCCAACGCCAATGTCAAGGGCACCCAGATCGGTGCCTACTTCGGGGCCTCCC
TCTGCTCCGTGGATGTGGACAGCAACGGCAGCACTGACCTTGTCCTCATCGGGGCCCCCTATTA
CTATGAGCAGACCCGAGGGGGCCAGGTGTCTGTGTGCCCCTTGCCCAGGGCGAGGGGTCGGTGG
CAGTGTGATGCTGTTCTCTACGGGGAGCAGGGCCAACCCTGGGGCCGCTTTGGGGCAGCCCTAA
CAGTGCTGGGGGATGTGAATGGAGACAAGCTGACGGATGTGGCCATTGGGGCCCCAGGAGAGGA
GGACAACCAGGGTGCTGTTTACCTGTTTCATGGAACCTCAGGATTTGGCATCAGCCCCTCCCAT
AGCCAGCGGATAGCAGGCTCCAAGCTCCCTCCCAGGCTCCAGTATTTTGGTCAGTCACTGAGTG
GGGGGCAGGACCTCACAATGGATGGACTGGTGGACCTGACTGTAGGAGCCCAGGGGCACGTGCT
GTTGTTCAGGTCCCAGCCAGTACTGAGAGTAGAGGCAACTATGGAGTTCAATCCCAGGGAAGTG
GCAAGGAATGTATTTGAGTGTAATGATCAGACGGTGAAAGGCAAGGAAGCTGGGGAGGTCAGAG
TCTGCCTCCATGTCCAGAAGAGCACACGGGATCGGCTAAGAGAAGGGCAGATCCAGAGTGTTGT
GACTTACGACCTGGCTCTGGACTCCGGCCCCCCACATTCCCGCGCTGTCTTCGGTGAGACAAAG
AACAGCACGCGCAGGCAGACGAAGACCTTGGGGCTGACCCGGACTTGTGAGACCCTGAAGCTAC
AGTTGCCGGATTGCATCGAGGACCCAGTGAGCCCCATTGTGCTGCGTCTGAACTTCTCTCTGGT
GGGAACTCCCTTGTCTGCTTTCGGGAACCTCCGGCCGGTGCTGGCTGAGGATGCTCAGAGAGTC
TTCATAGCCTTATTTCCCTTTGAGAAGAATTGTGGCAATGACAACATTTGCCAGGATGACCTCA
GCATCACCTTCAGTTTCATGAGCCTGGACTGCCTCGTGGTGGGTGGGCCCCGGGAGTTCAACGT
GACAGTGACTGTGAGAAATGATGGCGAGGACTCCTACAGGACACAGGTCACCTTCTTCTTCCCG
CTTGGCCTGTCCTACCGGAAGGTGTCCAGGCTCCAGAACCAGCGCTCACAGCGATCCTGGCGCC
TGGCCTGTGAGTCTGCCTCCTCCACCGAAGTGCCTGGGGCCTTGAAGAGCACCAGCTGCAGCAT
AAACCACCCCATCTTCCCAGAAAACTCAGAGGTCACCTTTAATATCACATTTGATGTGGACTCT
AAGGCTTCCCTTGGAAACAAACTGCTCCTCAAGGCCAATGTGACCAGTGAGAACAACATGTCCA
GAACCAACAAAACCGAATTCCAACGGGAGCTGCCGGTGAAATATGCTGTCTACATGGTGGTCAC
CAGCCATGAGGTCTCCACTAAATATCTCAACTTCACGGCCTCAGAGAATACCAGTCGGGTCATG
CAGCATCAATATCAGGTCAAAAACCTGGGGCAGAGGAGCCTCCCCATCAGCCTGGTATTCTTGG
TGCCTGTCCGGCTGAACCAGACGATCATATGGGACCGCCCCCAGGTCACTTTCTCCGAGAGCCT
CTCAAGTACGTGCCACACCGAGGAAATATTTCCCACCCCTCACACCGACTTTCTGGCTAAGCTT
CAGAAGGACCCAGTCGTGAACTGCTCCATCGCTGTCTGCCAGAGAATCAAGTGTGACATCCCGT
TCTTTGGCATCCAGGAAGAATTCAATGCCACCCTCAAAGGCAACCTCTCATTTGACTGGTACAT
CAAGACCTCGCATAACCACCTCCTGGTCGTGAGCACAGCTGAGATCATGTTTAACAATTCCACG
TTCACCCTGCTTCCGGGACAGGGGGCGTTTGTGAGGGCCCAGACGGAGACCAAAGTGGAGCCGT
TCGAGGTCCCCAACCCCTTGCCGCTCATCGTGGGCAGCTCTGTGGGGGGGCTGCTGCTCTTGGC
CCTCATCACCGCCGCGCTGTACAAGCTCGGCTTCTTCAAGCGGCAGTACAAGGACATGATGAGT
GAAGGGGGTCCCCCGGGGGCCGAACCCCAGTAGTGGCTCCTTCCCGACCGACCGAGCTGCCTCT
CCGTGGCCAGCAGGACTCTGCCCAGACCACACGTAGCCCCCAGGCTGCTGGACACACCGGACGG
CGAAGTCTCCTCGAGACAGGACCAGCTTGGGCTTACATTTGTGTGTGTGCAAGTGTGTATGTGC
ATGTGTGTGAGTGTGTGCAAGTGTCTATGTGCAAGCGTGTGGACATGTGTGCGTGTGTGTGCAC
TCACGCGTCCACGTGTGTGTGCAAGTATGTGTGTCCAAGTGTGTGCAAGTGTGTGTAAGCGTGT
GCATGTGTGTGCTCAGGGGTGTATGGCTCATGTGTGTGACTCAGATGTCTCTGGTGTGTGGGTA
GGTGGTGGCAGCGCAGCCTCTCTGGCAGAAGGGAACTGCCTGGGCTCCCTTGTGCGTGGGTGAA
GCCGCTGCTGGGTTTTCCTCCGGGACAGGCAAGGGTCAATCCTGTGGGTGAACACAGAGGGAAA
GGCAGCAGCTCCTCTCCACTGAAGGAAGTGGGACTTCCTGTCGCCGGAGAGCCTGCGGGGCCTG
CGGGAGCCAGCACAGCTTGGATGGAGATTCCGTGAGAAGCCGTGGGTGGAACCAGGAGCCTCAC
CAAACCCACTCCACACCAGCGCTGATGCCCAGTAAAGATGTCCACTGAGGAATGATGAATCTCC
CTTTATGGATTCATTTATTATTTCAATGTGACTTTAATTTTTTCAATGGATAAGCCTGTCTACG
GTACAAAAATCAAAAAGCATTCAAGAGTGTACAGTGAAAAGTCTCCCTTTCCAGATATTCAAGT
CACCTCCTTAAAGGTAGTCACGCTTGTGTTTTGAGGTTTCCTTGAGATTCCAGGCGATGTGCAA
ATGTATGCACGTGTGCACACACATACACCACACATACACACACACAAGCTTTTTTACACAAATG
GTAGCATACTTTGTATTGGTCTGTATCTTGCTTTTTTCCACTAATGTTTCTCAGACATCGGTTC
ATATTGACATAAATTACTTTTTCATTCTTTTATACCGCTGCATAGTATTCCATTGTGTGAGTGT
ACCATAGTGTAATTAACCAGTCTTCTTTTGATATATTATTTTCAATCTCTTGTTATTGCATCAA
TGCTGAGTTAATAAATCAAATATATGTCATTTTTGCATATATGTAAGGATAA

hide sequence

Protein Sequences


Protein RefSeqs	XP_007988928	(Get FASTA)	NCBI Sequence Viewer
	XP_007988937	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSCSAP00000002002.1

RefSeq Acc Id:	XP_007988928 ⟸ XM_007990737
- Peptide Label:	isoform X1
- UniProtKB:	A0A0D9R063 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_007988937 ⟸ XM_007990746
- Peptide Label:	isoform X2
- UniProtKB:	A0A0D9R063 (UniProtKB/TrEMBL)

Ensembl Acc Id:

ENSCSAP00000002002 ⟸ ENSCSAT00000003722

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSCSAG00000005696	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSCSAT00000003722.1	UniProtKB/TrEMBL
Gene3D-CATH	2.130.10.130	UniProtKB/TrEMBL
	3.40.50.410	UniProtKB/TrEMBL
	Bicelle-embedded integrin alpha(iib) transmembrane segment	UniProtKB/TrEMBL
	Integrin domains. Chain A, domain 2	UniProtKB/TrEMBL
	ntegrin, alpha v. Chain A, domain 3	UniProtKB/TrEMBL
	ntegrin, alpha v. Chain A, domain 4	UniProtKB/TrEMBL
InterPro	FG-GAP	UniProtKB/TrEMBL
	Int_alpha_beta-p	UniProtKB/TrEMBL
	Integrin_alpha	UniProtKB/TrEMBL
	Integrin_alpha-2	UniProtKB/TrEMBL
	Integrin_alpha_C_CS	UniProtKB/TrEMBL
	Integrin_alpha_Ig-like_2	UniProtKB/TrEMBL
	Integrin_alpha_N	UniProtKB/TrEMBL
	Integrin_dom_sf	UniProtKB/TrEMBL
	ITGAX-like_Ig_3	UniProtKB/TrEMBL
	VWF_A	UniProtKB/TrEMBL
	vWFA_dom_sf	UniProtKB/TrEMBL
NCBI Gene	ITGAM	ENTREZGENE
PANTHER	INTEGRIN ALPHA	UniProtKB/TrEMBL
	INTEGRIN ALPHA-M	UniProtKB/TrEMBL
Pfam	FG-GAP	UniProtKB/TrEMBL
	Integrin_A_Ig_2	UniProtKB/TrEMBL
	Integrin_alpha	UniProtKB/TrEMBL
	Integrin_alpha2	UniProtKB/TrEMBL
	ITGAX-like_Ig_3	UniProtKB/TrEMBL
	VWA	UniProtKB/TrEMBL
PRINTS	INTEGRINA	UniProtKB/TrEMBL
	VWFADOMAIN	UniProtKB/TrEMBL
PROSITE	FG_GAP	UniProtKB/TrEMBL
	INTEGRIN_ALPHA	UniProtKB/TrEMBL
	VWFA	UniProtKB/TrEMBL
SMART	Int_alpha	UniProtKB/TrEMBL
	VWA	UniProtKB/TrEMBL
Superfamily-SCOP	SSF53300	UniProtKB/TrEMBL
	SSF69179	UniProtKB/TrEMBL
	SSF69318	UniProtKB/TrEMBL
UniProt	A0A0D9R063	ENTREZGENE, UniProtKB/TrEMBL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Disease Annotations - ClinVar

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