Gene: Cfl1 (cofilin 1) Rattus norvegicus
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Symbol: Cfl1
Name: cofilin 1
Description: ENCODES a protein that exhibits actin binding; actin filament binding; phosphatidylinositol bisphosphate binding; INVOLVED IN cell projection organization; cellular response to epidermal growth factor stimulus; cellular response to ether; PARTICIPATES IN insulin responsive facilitative sugar transporter mediated glucose transport pathway; Rab family mediated signaling pathway; Fc gamma receptor mediated signaling pathway; ASSOCIATED WITH Cocaine-Related Disorders; Diabetic Cardiomyopathies; Diabetic Nephropathies; FOUND IN cell leading edge; cofilin-actin rod; cytoplasm; INTERACTS WITH 2,2',4,4'-Tetrabromodiphenyl ether; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: cofilin 1 non-muscle; cofilin 1, non-muscle; cofilin, non-muscle isoform; cofilin-1
Orthologs:
Homo sapiens (human) : CFL1 (cofilin 1)  HGNC  Alliance
Mus musculus (house mouse) : Cfl1 (cofilin 1, non-muscle)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Cfl1 (cofilin 1)
Pan paniscus (bonobo/pygmy chimpanzee) : CFL1 (cofilin 1)
Canis lupus familiaris (dog) : CFL1 (cofilin 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Cfl1 (cofilin 1)
Sus scrofa (pig) : CFL1 (cofilin 1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01220,869,805 - 220,873,337 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01227,799,126 - 227,802,658 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41208,133,876 - 208,137,408 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11208,287,328 - 208,290,861 (+)NCBI
Celera1200,333,275 - 200,336,807 (+)NCBICelera
Cytogenetic Map1q43NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Cfl1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 69285
Created: 2001-11-14
Species: Rattus norvegicus
Last Modified: 2019-01-30
Status: ACTIVE