Symbol:
Pola2
Name:
DNA polymerase alpha 2, accessory subunit
RGD ID:
621817
Description:
Enables DNA-directed DNA polymerase activity. Involved in DNA replication. Predicted to be located in ciliary basal body; cytosol; and nucleoplasm. Predicted to be part of alpha DNA polymerase:primase complex. Orthologous to human POLA2 (DNA polymerase alpha 2, accessory subunit); PARTICIPATES IN DNA replication pathway; purine metabolic pathway; pyrimidine metabolic pathway; INTERACTS WITH 17alpha-ethynylestradiol; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine.
Type:
protein-coding
RefSeq Status:
PROVISIONAL
Previously known as:
DNA polymerase alpha 70 kDa subunit; DNA polymerase alpha subunit B; DNA polymerase alpha subunit II; DNA polymerase subunit II; DNA-directed DNA polymerase alpha 2; polymerase (DNA directed), alpha 2; polymerase (DNA directed), alpha 2, accessory subunit; polymerase (DNA) alpha 2, accessory subunit
RGD Orthologs
Alliance Orthologs
More Info
more info ...
More Info
Species
Gene symbol and name
Data Source
Assertion derived from
less info ...
Orthologs 1
Homo sapiens (human):
POLA2 (DNA polymerase alpha 2, accessory subunit) HGNC
EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, Treefam
Mus musculus (house mouse):
Pola2 (polymerase (DNA directed), alpha 2) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):
Pola2 (DNA polymerase alpha 2, accessory subunit) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):
POLA2 (DNA polymerase alpha 2, accessory subunit) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Canis lupus familiaris (dog):
POLA2 (DNA polymerase alpha 2, accessory subunit) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):
Pola2 (DNA polymerase alpha 2, accessory subunit) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Sus scrofa (pig):
POLA2 (DNA polymerase alpha 2, accessory subunit) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):
POLA2 (DNA polymerase alpha 2, accessory subunit) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):
Pola2 (DNA polymerase alpha 2, accessory subunit) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Alliance orthologs 3
Homo sapiens (human):
POLA2 (DNA polymerase alpha 2, accessory subunit)
Alliance
DIOPT (Ensembl Compara|HGNC|Hieranoid|InParanoid|OMA|OrthoFinder|OrthoInspector|PANTHER|PhylomeDB|SonicParanoid)
Mus musculus (house mouse):
Pola2 (polymerase (DNA directed), alpha 2)
Alliance
DIOPT (Ensembl Compara|Hieranoid|InParanoid|OMA|OrthoFinder|OrthoInspector|PANTHER|PhylomeDB|SonicParanoid)
Danio rerio (zebrafish):
pola2 (polymerase (DNA directed), alpha 2)
Alliance
DIOPT (Ensembl Compara|Hieranoid|InParanoid|OMA|OrthoFinder|OrthoInspector|PANTHER|PhylomeDB|SonicParanoid)
Caenorhabditis elegans (roundworm):
div-1
Alliance
DIOPT (Ensembl Compara|InParanoid|OMA|OrthoFinder|OrthoInspector|PANTHER|PhylomeDB|SonicParanoid)
Drosophila melanogaster (fruit fly):
DNApol-alpha73
Alliance
DIOPT (Ensembl Compara|Hieranoid|InParanoid|OMA|OrthoFinder|OrthoInspector|PANTHER|PhylomeDB|SonicParanoid)
Saccharomyces cerevisiae (baker's yeast):
POL12
Alliance
DIOPT (Ensembl Compara|Hieranoid|InParanoid|OrthoFinder|OrthoInspector|PANTHER|PhylomeDB|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):
pola2
Alliance
DIOPT (Ensembl Compara|Hieranoid|InParanoid|OMA|OrthoFinder|OrthoInspector|PANTHER|PhylomeDB)
Latest Assembly:
GRCr8 - GRCr8 Assembly
Position:
Rat Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl GRCr8 1 212,656,500 - 212,680,667 (-) NCBI GRCr8 mRatBN7.2 1 203,227,183 - 203,251,350 (-) NCBI mRatBN7.2 mRatBN7.2 mRatBN7.2 Ensembl 1 203,203,388 - 203,251,348 (-) Ensembl mRatBN7.2 Ensembl UTH_Rnor_SHR_Utx 1 211,580,596 - 211,604,656 (-) NCBI Rnor_SHR UTH_Rnor_SHR_Utx UTH_Rnor_SHRSP_BbbUtx_1.0 1 218,672,575 - 218,696,619 (-) NCBI Rnor_SHRSP UTH_Rnor_SHRSP_BbbUtx_1.0 UTH_Rnor_WKY_Bbb_1.0 1 211,363,633 - 211,387,678 (-) NCBI Rnor_WKY UTH_Rnor_WKY_Bbb_1.0 Rnor_6.0 1 221,297,417 - 221,321,601 (-) NCBI Rnor6.0 Rnor_6.0 rn6 Rnor6.0 Rnor_6.0 Ensembl 1 221,273,538 - 221,321,570 (-) Ensembl Rnor6.0 rn6 Rnor6.0 Rnor_5.0 1 228,231,866 - 228,255,908 (-) NCBI Rnor5.0 Rnor_5.0 rn5 Rnor5.0 RGSC_v3.4 1 208,573,153 - 208,597,195 (-) NCBI RGSC3.4 RGSC_v3.4 rn4 RGSC3.4 RGSC_v3.1 1 208,726,606 - 208,750,648 (-) NCBI Celera 1 200,761,869 - 200,785,913 (-) NCBI Celera Cytogenetic Map 1 q43 NCBI
JBrowse:
View Region in Genome Browser (JBrowse)
Model
Only show annotations with direct experimental evidence (0 objects hidden)
Pola2 Rat (-)-demecolcine decreases expression ISO RGD:731623 6480464 Demecolcine results in decreased expression of POLA2 mRNA CTD PMID:23649840 Pola2 Rat (-)-epigallocatechin 3-gallate multiple interactions ISO RGD:731623 6480464 [potassium chromate(VI) co-treated with epigallocatechin gallate] results in decreased expression of POLA2 mRNA CTD PMID:22079256 Pola2 Rat 1,2,4-trichloro-5-(2,5-dichlorophenyl)benzene multiple interactions ISO RGD:731624 6480464 [2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with more ... CTD PMID:25510870 Pola2 Rat 1,2-dimethylhydrazine increases expression ISO RGD:731624 6480464 1,2-Dimethylhydrazine results in increased expression of POLA2 mRNA CTD PMID:22206623 Pola2 Rat 17alpha-ethynylestradiol affects expression EXP 6480464 Ethinyl Estradiol affects the expression of POLA2 mRNA CTD PMID:17351261 Pola2 Rat 17beta-estradiol increases expression EXP 6480464 Estradiol results in increased expression of POLA2 mRNA CTD PMID:32145629 Pola2 Rat 2,2',4,4',5,5'-hexachlorobiphenyl multiple interactions ISO RGD:731624 6480464 [2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with more ... CTD PMID:25510870 Pola2 Rat 2,2',5,5'-tetrachlorobiphenyl multiple interactions ISO RGD:731624 6480464 [2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with more ... CTD PMID:25510870 Pola2 Rat 2,2'-Methylenebis(4-methyl-6-tert-butylphenol) multiple interactions ISO RGD:731623 6480464 [CYP3A4 protein affects the susceptibility to 2,2'-methylenebis(4-methyl-6-tert-butylphenol)] which affects the expression of POLA2 mRNA CTD PMID:38160208 Pola2 Rat 2,3,7,8-tetrachlorodibenzodioxine increases expression EXP 6480464 Tetrachlorodibenzodioxin results in increased expression of POLA2 mRNA CTD PMID:16960034 Pola2 Rat 2,3,7,8-tetrachlorodibenzodioxine decreases expression EXP 6480464 Tetrachlorodibenzodioxin results in decreased expression of POLA2 mRNA CTD PMID:34747641 Pola2 Rat 2,3,7,8-tetrachlorodibenzodioxine affects expression ISO RGD:731624 6480464 Tetrachlorodibenzodioxin affects the expression of POLA2 mRNA CTD PMID:21570461 Pola2 Rat 2,3,7,8-tetrachlorodibenzodioxine increases expression ISO RGD:731624 6480464 Tetrachlorodibenzodioxin results in increased expression of POLA2 mRNA CTD PMID:16960034|PMID:19465110 Pola2 Rat 2,4,4'-trichlorobiphenyl multiple interactions ISO RGD:731624 6480464 [2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with more ... CTD PMID:25510870 Pola2 Rat 2-hydroxypropanoic acid increases expression ISO RGD:731623 6480464 Lactic Acid results in increased expression of POLA2 mRNA CTD PMID:30851411 Pola2 Rat 3,3',4,4',5-pentachlorobiphenyl increases expression EXP 6480464 3,4,5,3',4'-pentachlorobiphenyl results in increased expression of POLA2 mRNA CTD PMID:23196670 Pola2 Rat 3,4-methylenedioxymethamphetamine increases expression ISO RGD:731624 6480464 N-Methyl-3,4-methylenedioxyamphetamine results in increased expression of POLA2 mRNA CTD PMID:26251327 Pola2 Rat 4,4'-sulfonyldiphenol decreases expression ISO RGD:731624 6480464 bisphenol S results in decreased expression of POLA2 mRNA CTD PMID:39298647 Pola2 Rat 4-(ethoxymethylene)-2-phenyloxazol-5-one increases expression ISO RGD:731624 6480464 Oxazolone results in increased expression of POLA2 mRNA CTD PMID:21404309 Pola2 Rat 5-fluorouracil affects response to substance ISO RGD:731623 6480464 POLA2 protein affects the susceptibility to Fluorouracil CTD PMID:15548681 Pola2 Rat 6-propyl-2-thiouracil increases expression EXP 6480464 Propylthiouracil results in increased expression of POLA2 mRNA CTD PMID:24780913 Pola2 Rat acetamide increases expression EXP 6480464 acetamide results in increased expression of POLA2 mRNA CTD PMID:31881176 Pola2 Rat acrylamide increases expression EXP 6480464 Acrylamide results in increased expression of POLA2 mRNA CTD PMID:28959563 Pola2 Rat acrylamide decreases expression ISO RGD:731623 6480464 Acrylamide results in decreased expression of POLA2 mRNA CTD PMID:32763439 Pola2 Rat alpha-Zearalanol multiple interactions EXP 6480464 [Zeranol co-treated with perfluorooctanoic acid] results in increased expression of POLA2 mRNA CTD PMID:35163327 Pola2 Rat ammonium chloride affects expression EXP 6480464 Ammonium Chloride affects the expression of POLA2 mRNA CTD PMID:16483693 Pola2 Rat aristolochic acid A decreases expression ISO RGD:731623 6480464 aristolochic acid I results in decreased expression of POLA2 mRNA; aristolochic acid I results in more ... CTD PMID:33212167 Pola2 Rat arsane multiple interactions ISO RGD:731623 6480464 [sodium arsenite results in increased abundance of Arsenic] which results in decreased expression of POLA2 more ... CTD PMID:39836092 Pola2 Rat arsenic atom multiple interactions ISO RGD:731623 6480464 [sodium arsenite results in increased abundance of Arsenic] which results in decreased expression of POLA2 more ... CTD PMID:39836092 Pola2 Rat arsenite ion multiple interactions EXP 6480464 [AS3MT protein results in increased susceptibility to Arsenites] which affects the expression of POLA2 mRNA CTD PMID:19411561 Pola2 Rat atrazine decreases expression ISO RGD:731623 6480464 Atrazine results in decreased expression of POLA2 mRNA CTD PMID:22378314 Pola2 Rat benzo[a]pyrene increases expression ISO RGD:731623 6480464 Benzo(a)pyrene results in increased expression of POLA2 mRNA CTD PMID:32234424|PMID:33411230 Pola2 Rat bis(2-ethylhexyl) phthalate increases expression ISO RGD:731624 6480464 Diethylhexyl Phthalate results in increased expression of POLA2 mRNA CTD PMID:34319233 Pola2 Rat bisphenol A decreases expression EXP 6480464 bisphenol A results in decreased expression of POLA2 mRNA CTD PMID:25181051|PMID:30816183|PMID:32528016 Pola2 Rat bisphenol A increases expression EXP 6480464 bisphenol A results in increased expression of POLA2 mRNA CTD PMID:32145629 Pola2 Rat bisphenol A decreases expression ISO RGD:731623 6480464 bisphenol A results in decreased expression of POLA2 mRNA CTD PMID:29275510 Pola2 Rat caffeine affects phosphorylation ISO RGD:731623 6480464 Caffeine affects the phosphorylation of POLA2 protein CTD PMID:35688186 Pola2 Rat calcitriol decreases expression ISO RGD:731623 6480464 Calcitriol results in decreased expression of POLA2 mRNA CTD PMID:21592394 Pola2 Rat calcitriol multiple interactions ISO RGD:731623 6480464 [Testosterone co-treated with Calcitriol] results in decreased expression of POLA2 mRNA CTD PMID:21592394 Pola2 Rat cannabidiol decreases expression ISO RGD:731623 6480464 Cannabidiol results in decreased expression of POLA2 mRNA CTD PMID:36519830 Pola2 Rat cefaloridine increases expression EXP 6480464 Cephaloridine results in increased expression of POLA2 mRNA CTD PMID:18500788 Pola2 Rat chromium(6+) multiple interactions ISO RGD:731623 6480464 [zinc chromate results in increased abundance of chromium hexavalent ion] which results in decreased expression more ... CTD PMID:38479592 Pola2 Rat cisplatin increases expression ISO RGD:731623 6480464 Cisplatin results in increased expression of POLA2 mRNA CTD PMID:27392435|PMID:27594783 Pola2 Rat cisplatin multiple interactions ISO RGD:731623 6480464 [Cisplatin co-treated with jinfukang] results in increased expression of POLA2 mRNA CTD PMID:27392435 Pola2 Rat clofibric acid affects expression EXP 6480464 Clofibric Acid affects the expression of POLA2 mRNA CTD PMID:17602206 Pola2 Rat cobalt dichloride decreases expression ISO RGD:731623 6480464 cobaltous chloride results in decreased expression of POLA2 mRNA CTD PMID:19320972 Pola2 Rat copper atom multiple interactions ISO RGD:731623 6480464 [NSC 689534 binds to Copper] which results in decreased expression of POLA2 mRNA CTD PMID:20971185 Pola2 Rat copper(0) multiple interactions ISO RGD:731623 6480464 [NSC 689534 binds to Copper] which results in decreased expression of POLA2 mRNA CTD PMID:20971185 Pola2 Rat copper(II) sulfate decreases expression ISO RGD:731623 6480464 Copper Sulfate results in decreased expression of POLA2 mRNA CTD PMID:19549813 Pola2 Rat coumarin increases phosphorylation ISO RGD:731623 6480464 coumarin results in increased phosphorylation of POLA2 protein CTD PMID:35688186 Pola2 Rat coumestrol multiple interactions ISO RGD:731623 6480464 [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of POLA2 mRNA; [Coumestrol co-treated with resveratrol] more ... CTD PMID:19167446 Pola2 Rat coumestrol increases expression ISO RGD:731623 6480464 Coumestrol results in increased expression of POLA2 mRNA CTD PMID:19167446 Pola2 Rat curcumin decreases expression EXP 6480464 Curcumin results in decreased expression of POLA2 mRNA CTD PMID:18299980 Pola2 Rat cyclosporin A decreases expression ISO RGD:731623 6480464 Cyclosporine results in decreased expression of POLA2 mRNA CTD PMID:20106945|PMID:21632981|PMID:25562108 Pola2 Rat dibutyl phthalate decreases expression EXP 6480464 Dibutyl Phthalate results in decreased expression of POLA2 mRNA CTD PMID:21266533 Pola2 Rat dioxygen decreases expression ISO RGD:731623 6480464 Oxygen deficiency results in decreased expression of POLA2 mRNA CTD PMID:26516004 Pola2 Rat doxorubicin decreases expression ISO RGD:731623 6480464 Doxorubicin results in decreased expression of POLA2 mRNA CTD PMID:29803840 Pola2 Rat elemental selenium increases expression ISO RGD:731623 6480464 Selenium results in increased expression of POLA2 mRNA CTD PMID:19244175 Pola2 Rat endosulfan increases expression EXP 6480464 Endosulfan results in increased expression of POLA2 mRNA CTD PMID:29391264 Pola2 Rat Enterolactone multiple interactions ISO RGD:731623 6480464 [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of POLA2 mRNA CTD PMID:19167446 Pola2 Rat enzyme inhibitor multiple interactions ISO RGD:731623 6480464 [Enzyme Inhibitors results in decreased activity of OGA protein] which results in increased O-linked glycosylation more ... CTD PMID:23301498 Pola2 Rat FR900359 affects phosphorylation ISO RGD:731623 6480464 FR900359 affects the phosphorylation of POLA2 protein CTD PMID:37730182 Pola2 Rat glycine betaine decreases expression EXP 6480464 Betaine results in decreased expression of POLA2 mRNA CTD PMID:26391144 Pola2 Rat GSK-J4 decreases expression ISO RGD:731623 6480464 GSK-J4 results in decreased expression of POLA2 mRNA CTD PMID:29301935 Pola2 Rat hydrogen peroxide multiple interactions ISO RGD:731624 6480464 [Hydrogen Peroxide co-treated with N-(oxo-5,6-dihydrophenanthridin-2-yl)-N,N-dimethylacetamide hydrochloride] results in increased phosphorylation of POLA2 protein CTD PMID:31494107 Pola2 Rat leflunomide decreases expression ISO RGD:731623 6480464 leflunomide results in decreased expression of POLA2 mRNA CTD PMID:28988120 Pola2 Rat methamphetamine increases expression ISO RGD:731624 6480464 Methamphetamine results in increased expression of POLA2 mRNA CTD PMID:26307267 Pola2 Rat methyl methanesulfonate increases expression ISO RGD:731623 6480464 Methyl Methanesulfonate results in increased expression of POLA2 mRNA CTD PMID:23649840 Pola2 Rat N-(6-acetamidohexyl)acetamide decreases expression ISO RGD:731624 6480464 hexamethylene bisacetamide results in decreased expression of POLA2 mRNA CTD PMID:26941288 Pola2 Rat nickel atom increases expression ISO RGD:731623 6480464 Nickel results in increased expression of POLA2 mRNA CTD PMID:24768652|PMID:25583101 Pola2 Rat okadaic acid increases expression ISO RGD:731623 6480464 Okadaic Acid results in increased expression of POLA2 mRNA CTD PMID:38832940 Pola2 Rat oxaliplatin multiple interactions EXP 6480464 [oxaliplatin co-treated with Topotecan] results in decreased expression of POLA2 mRNA CTD PMID:25729387 Pola2 Rat ozone multiple interactions ISO RGD:731623 6480464 [Air Pollutants results in increased abundance of Ozone] which affects the expression of POLA2 mRNA CTD PMID:35430440 Pola2 Rat palbociclib decreases expression ISO RGD:731623 6480464 palbociclib results in decreased expression of POLA2 mRNA CTD PMID:22869556 Pola2 Rat paracetamol increases expression ISO RGD:731623 6480464 Acetaminophen results in increased expression of POLA2 mRNA CTD PMID:22230336 Pola2 Rat PCB138 multiple interactions ISO RGD:731624 6480464 [2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with more ... CTD PMID:25510870 Pola2 Rat perfluorononanoic acid decreases expression ISO RGD:731623 6480464 perfluoro-n-nonanoic acid results in decreased expression of POLA2 mRNA CTD PMID:32588087 Pola2 Rat perfluorooctane-1-sulfonic acid increases expression EXP 6480464 perfluorooctane sulfonic acid results in increased expression of POLA2 mRNA CTD PMID:16221955 Pola2 Rat perfluorooctane-1-sulfonic acid multiple interactions ISO RGD:731624 6480464 [perfluorooctane sulfonic acid co-treated with Pectins] results in decreased expression of POLA2 mRNA CTD PMID:36331819 Pola2 Rat perfluorooctanoic acid multiple interactions EXP 6480464 [Zeranol co-treated with perfluorooctanoic acid] results in increased expression of POLA2 mRNA CTD PMID:35163327 Pola2 Rat phenethyl isothiocyanate decreases expression ISO RGD:731623 6480464 phenethyl isothiocyanate results in decreased expression of POLA2 mRNA CTD PMID:26678675 Pola2 Rat phenobarbital affects expression ISO RGD:731623 6480464 Phenobarbital affects the expression of POLA2 mRNA CTD PMID:19159669 Pola2 Rat pirinixic acid multiple interactions ISO RGD:731623 6480464 [pirinixic acid binds to and results in increased activity of PPARA protein] which results in more ... CTD PMID:19710929 Pola2 Rat potassium chromate decreases expression ISO RGD:731623 6480464 potassium chromate(VI) results in decreased expression of POLA2 mRNA CTD PMID:22079256 Pola2 Rat potassium chromate multiple interactions ISO RGD:731623 6480464 [potassium chromate(VI) co-treated with epigallocatechin gallate] results in decreased expression of POLA2 mRNA CTD PMID:22079256 Pola2 Rat rac-lactic acid increases expression ISO RGD:731623 6480464 Lactic Acid results in increased expression of POLA2 mRNA CTD PMID:30851411 Pola2 Rat resveratrol multiple interactions ISO RGD:731623 6480464 [Coumestrol co-treated with resveratrol] results in increased expression of POLA2 mRNA CTD PMID:19167446 Pola2 Rat resveratrol increases expression EXP 6480464 resveratrol results in increased expression of POLA2 mRNA CTD PMID:25905778 Pola2 Rat selenium atom increases expression ISO RGD:731623 6480464 Selenium results in increased expression of POLA2 mRNA CTD PMID:19244175 Pola2 Rat silicon dioxide decreases expression EXP 6480464 Silicon Dioxide results in decreased expression of POLA2 mRNA CTD PMID:22431001 Pola2 Rat sodium arsenate increases expression ISO RGD:731624 6480464 sodium arsenate results in increased expression of POLA2 mRNA CTD PMID:30953684 Pola2 Rat sodium arsenite decreases expression ISO RGD:731623 6480464 sodium arsenite results in decreased expression of POLA2 mRNA CTD PMID:38568856 Pola2 Rat sodium arsenite multiple interactions ISO RGD:731623 6480464 [sodium arsenite results in increased abundance of Arsenic] which results in decreased expression of POLA2 more ... CTD PMID:39836092 Pola2 Rat sodium arsenite increases expression ISO RGD:731623 6480464 sodium arsenite results in increased expression of POLA2 mRNA CTD PMID:34032870 Pola2 Rat sodium dichromate affects expression EXP 6480464 sodium bichromate affects the expression of POLA2 mRNA CTD PMID:22110744 Pola2 Rat Soman increases expression EXP 6480464 Soman results in increased expression of POLA2 mRNA CTD PMID:19281266 Pola2 Rat sunitinib decreases expression ISO RGD:731623 6480464 Sunitinib results in decreased expression of POLA2 mRNA CTD PMID:31533062 Pola2 Rat testosterone multiple interactions ISO RGD:731623 6480464 [Testosterone co-treated with Calcitriol] results in decreased expression of POLA2 mRNA CTD PMID:21592394 Pola2 Rat testosterone decreases expression ISO RGD:731623 6480464 Testosterone results in decreased expression of POLA2 mRNA CTD PMID:21592394 Pola2 Rat thapsigargin decreases expression ISO RGD:731623 6480464 Thapsigargin results in decreased expression of POLA2 mRNA CTD PMID:22378314 Pola2 Rat thioacetamide increases expression EXP 6480464 Thioacetamide results in increased expression of POLA2 mRNA CTD PMID:23411599|PMID:34492290 Pola2 Rat thiram decreases expression ISO RGD:731623 6480464 Thiram results in decreased expression of POLA2 mRNA CTD PMID:38568856 Pola2 Rat toluene 2,4-diisocyanate increases expression ISO RGD:731624 6480464 Toluene 2,4-Diisocyanate results in increased expression of POLA2 mRNA CTD PMID:21404309 Pola2 Rat topotecan multiple interactions EXP 6480464 [oxaliplatin co-treated with Topotecan] results in decreased expression of POLA2 mRNA CTD PMID:25729387 Pola2 Rat topotecan decreases expression EXP 6480464 Topotecan results in decreased expression of POLA2 mRNA CTD PMID:25729387 Pola2 Rat trimellitic anhydride increases expression ISO RGD:731624 6480464 trimellitic anhydride results in increased expression of POLA2 mRNA CTD PMID:19042947 Pola2 Rat triphenyl phosphate affects expression ISO RGD:731623 6480464 triphenyl phosphate affects the expression of POLA2 mRNA CTD PMID:37042841 Pola2 Rat troglitazone decreases expression ISO RGD:731623 6480464 troglitazone results in decreased expression of POLA2 mRNA CTD PMID:19140230 Pola2 Rat urethane decreases expression ISO RGD:731623 6480464 Urethane results in decreased expression of POLA2 mRNA CTD PMID:28818685
Imported Annotations - KEGG (archival)
(-)-demecolcine (ISO) (-)-epigallocatechin 3-gallate (ISO) 1,2,4-trichloro-5-(2,5-dichlorophenyl)benzene (ISO) 1,2-dimethylhydrazine (ISO) 17alpha-ethynylestradiol (EXP) 17beta-estradiol (EXP) 2,2',4,4',5,5'-hexachlorobiphenyl (ISO) 2,2',5,5'-tetrachlorobiphenyl (ISO) 2,2'-Methylenebis(4-methyl-6-tert-butylphenol) (ISO) 2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO) 2,4,4'-trichlorobiphenyl (ISO) 2-hydroxypropanoic acid (ISO) 3,3',4,4',5-pentachlorobiphenyl (EXP) 3,4-methylenedioxymethamphetamine (ISO) 4,4'-sulfonyldiphenol (ISO) 4-(ethoxymethylene)-2-phenyloxazol-5-one (ISO) 5-fluorouracil (ISO) 6-propyl-2-thiouracil (EXP) acetamide (EXP) acrylamide (EXP,ISO) alpha-Zearalanol (EXP) ammonium chloride (EXP) aristolochic acid A (ISO) arsane (ISO) arsenic atom (ISO) arsenite ion (EXP) atrazine (ISO) benzo[a]pyrene (ISO) bis(2-ethylhexyl) phthalate (ISO) bisphenol A (EXP,ISO) caffeine (ISO) calcitriol (ISO) cannabidiol (ISO) cefaloridine (EXP) chromium(6+) (ISO) cisplatin (ISO) clofibric acid (EXP) cobalt dichloride (ISO) copper atom (ISO) copper(0) (ISO) copper(II) sulfate (ISO) coumarin (ISO) coumestrol (ISO) curcumin (EXP) cyclosporin A (ISO) dibutyl phthalate (EXP) dioxygen (ISO) doxorubicin (ISO) elemental selenium (ISO) endosulfan (EXP) Enterolactone (ISO) enzyme inhibitor (ISO) FR900359 (ISO) glycine betaine (EXP) GSK-J4 (ISO) hydrogen peroxide (ISO) leflunomide (ISO) methamphetamine (ISO) methyl methanesulfonate (ISO) N-(6-acetamidohexyl)acetamide (ISO) nickel atom (ISO) okadaic acid (ISO) oxaliplatin (EXP) ozone (ISO) palbociclib (ISO) paracetamol (ISO) PCB138 (ISO) perfluorononanoic acid (ISO) perfluorooctane-1-sulfonic acid (EXP,ISO) perfluorooctanoic acid (EXP) phenethyl isothiocyanate (ISO) phenobarbital (ISO) pirinixic acid (ISO) potassium chromate (ISO) rac-lactic acid (ISO) resveratrol (EXP,ISO) selenium atom (ISO) silicon dioxide (EXP) sodium arsenate (ISO) sodium arsenite (ISO) sodium dichromate (EXP) Soman (EXP) sunitinib (ISO) testosterone (ISO) thapsigargin (ISO) thioacetamide (EXP) thiram (ISO) toluene 2,4-diisocyanate (ISO) topotecan (EXP) trimellitic anhydride (ISO) triphenyl phosphate (ISO) troglitazone (ISO) urethane (ISO)
Pola2 Rat Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl GRCr8 1 212,656,500 - 212,680,667 (-) NCBI GRCr8 mRatBN7.2 1 203,227,183 - 203,251,350 (-) NCBI mRatBN7.2 mRatBN7.2 mRatBN7.2 Ensembl 1 203,203,388 - 203,251,348 (-) Ensembl mRatBN7.2 Ensembl UTH_Rnor_SHR_Utx 1 211,580,596 - 211,604,656 (-) NCBI Rnor_SHR UTH_Rnor_SHR_Utx UTH_Rnor_SHRSP_BbbUtx_1.0 1 218,672,575 - 218,696,619 (-) NCBI Rnor_SHRSP UTH_Rnor_SHRSP_BbbUtx_1.0 UTH_Rnor_WKY_Bbb_1.0 1 211,363,633 - 211,387,678 (-) NCBI Rnor_WKY UTH_Rnor_WKY_Bbb_1.0 Rnor_6.0 1 221,297,417 - 221,321,601 (-) NCBI Rnor6.0 Rnor_6.0 rn6 Rnor6.0 Rnor_6.0 Ensembl 1 221,273,538 - 221,321,570 (-) Ensembl Rnor6.0 rn6 Rnor6.0 Rnor_5.0 1 228,231,866 - 228,255,908 (-) NCBI Rnor5.0 Rnor_5.0 rn5 Rnor5.0 RGSC_v3.4 1 208,573,153 - 208,597,195 (-) NCBI RGSC3.4 RGSC_v3.4 rn4 RGSC3.4 RGSC_v3.1 1 208,726,606 - 208,750,648 (-) NCBI Celera 1 200,761,869 - 200,785,913 (-) NCBI Celera Cytogenetic Map 1 q43 NCBI
POLA2 Human Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl GRCh38 11 65,261,962 - 65,305,985 (+) NCBI GRCh38 GRCh38 hg38 GRCh38 GRCh38.p14 Ensembl 11 65,261,913 - 65,305,959 (+) Ensembl GRCh38 hg38 GRCh38 GRCh37 11 65,029,433 - 65,066,156 (+) NCBI GRCh37 GRCh37 hg19 GRCh37 Build 36 11 64,786,006 - 64,821,664 (+) NCBI NCBI36 Build 36 hg18 NCBI36 Build 34 11 64,786,007 - 64,821,663 NCBI Celera 11 62,355,790 - 62,391,446 (+) NCBI Celera Cytogenetic Map 11 q13.1 NCBI HuRef 11 61,356,467 - 61,392,125 (+) NCBI HuRef CHM1_1 11 64,913,445 - 64,949,101 (+) NCBI CHM1_1 T2T-CHM13v2.0 11 65,255,287 - 65,299,590 (+) NCBI T2T-CHM13v2.0
Pola2 Mouse Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl GRCm39 19 5,990,574 - 6,014,266 (-) NCBI GRCm39 GRCm39 mm39 GRCm39 Ensembl 19 5,990,570 - 6,014,230 (-) Ensembl GRCm39 Ensembl GRCm38 19 5,940,543 - 5,964,238 (-) NCBI GRCm38 GRCm38 mm10 GRCm38 GRCm38.p6 Ensembl 19 5,940,542 - 5,964,202 (-) Ensembl GRCm38 mm10 GRCm38 MGSCv37 19 5,940,543 - 5,964,206 (-) NCBI GRCm37 MGSCv37 mm9 NCBIm37 MGSCv36 19 5,940,546 - 5,964,170 (-) NCBI MGSCv36 mm8 Celera 19 5,810,597 - 5,834,275 (-) NCBI Celera Cytogenetic Map 19 A NCBI cM Map 19 4.34 NCBI
Pola2 Chinchilla Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl ChiLan1.0 Ensembl NW_004955422 19,939,933 - 19,963,753 (-) Ensembl ChiLan1.0 ChiLan1.0 NW_004955422 19,939,971 - 19,963,753 (-) NCBI ChiLan1.0 ChiLan1.0
POLA2 Bonobo Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl NHGRI_mPanPan1-v2 9 66,494,901 - 66,540,751 (+) NCBI NHGRI_mPanPan1-v2 NHGRI_mPanPan1 11 67,539,404 - 67,584,852 (+) NCBI NHGRI_mPanPan1 Mhudiblu_PPA_v0 11 60,626,555 - 60,670,716 (+) NCBI Mhudiblu_PPA_v0 Mhudiblu_PPA_v0 panPan3 PanPan1.1 11 63,966,001 - 64,001,690 (+) NCBI panpan1.1 PanPan1.1 panPan2 PanPan1.1 Ensembl 11 63,966,531 - 64,001,335 (+) Ensembl panpan1.1 panPan2
POLA2 Dog Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl CanFam3.1 18 51,875,860 - 51,904,492 (-) NCBI CanFam3.1 CanFam3.1 canFam3 CanFam3.1 CanFam3.1 Ensembl 18 51,875,903 - 51,904,746 (-) Ensembl CanFam3.1 canFam3 CanFam3.1 Dog10K_Boxer_Tasha 18 50,483,874 - 50,512,505 (-) NCBI Dog10K_Boxer_Tasha ROS_Cfam_1.0 18 52,917,422 - 52,946,062 (-) NCBI ROS_Cfam_1.0 ROS_Cfam_1.0 Ensembl 18 52,916,305 - 52,946,308 (-) Ensembl ROS_Cfam_1.0 Ensembl UMICH_Zoey_3.1 18 52,013,341 - 52,041,972 (-) NCBI UMICH_Zoey_3.1 UNSW_CanFamBas_1.0 18 51,586,490 - 51,614,915 (-) NCBI UNSW_CanFamBas_1.0 UU_Cfam_GSD_1.0 18 52,380,631 - 52,409,289 (-) NCBI UU_Cfam_GSD_1.0
Pola2 Squirrel Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl HiC_Itri_2 NW_024404947 7,663,010 - 7,689,743 (-) NCBI HiC_Itri_2 SpeTri2.0 Ensembl NW_004936599 4,105,301 - 4,132,054 (-) Ensembl SpeTri2.0 SpeTri2.0 Ensembl SpeTri2.0 NW_004936599 4,105,365 - 4,132,079 (-) NCBI SpeTri2.0 SpeTri2.0 SpeTri2.0
POLA2 Pig Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl Sscrofa11.1 Ensembl 2 6,922,387 - 6,950,179 (-) Ensembl Sscrofa11.1 susScr11 Sscrofa11.1 Sscrofa11.1 2 6,922,384 - 6,950,289 (-) NCBI Sscrofa11.1 Sscrofa11.1 susScr11 Sscrofa11.1 Sscrofa10.2 2 6,054,435 - 6,082,311 (-) NCBI Sscrofa10.2 Sscrofa10.2 susScr3
POLA2 Green Monkey Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl ChlSab1.1 1 8,940,102 - 8,977,049 (-) NCBI ChlSab1.1 ChlSab1.1 chlSab2 ChlSab1.1 Ensembl 1 8,938,769 - 8,976,771 (-) Ensembl ChlSab1.1 ChlSab1.1 Ensembl chlSab2 Vero_WHO_p1.0 NW_023666038 106,310,399 - 106,346,750 (-) NCBI Vero_WHO_p1.0 Vero_WHO_p1.0
Pola2
.
Predicted Target Of
Count of predictions: 54 Count of miRNA genes: 44 Interacting mature miRNAs: 50 Transcripts: ENSRNOT00000028406 Prediction methods: Miranda, Rnahybrid, Targetscan Result types: miRGate_prediction
1578778 Pur4 Proteinuria QTL 4 3.3 0.003 urine total protein amount (VT:0000032) urine total protein excretion rate (CMO:0000756) 1 150700247 252085048 Rat 1354646 Kidm18 Kidney mass QTL 18 5.7 kidney mass (VT:0002707) calculated kidney weight (CMO:0000160) 1 151162512 256448636 Rat 1357335 Bw39 Body weight QTL 39 3.3 body mass (VT:0001259) body weight (CMO:0000012) 1 197814409 242814409 Rat 1578780 Cm52 Cardiac mass QTL 52 3.3 0.0001 heart mass (VT:0007028) heart wet weight (CMO:0000069) 1 81591954 219808434 Rat 2302375 Bw83 Body weight QTL 83 4.87 0.0002 body mass (VT:0001259) body weight (CMO:0000012) 1 197697768 242697768 Rat 1354652 Kidm20 Kidney mass QTL 20 4.3 kidney mass (VT:0002707) calculated kidney weight (CMO:0000160) 1 177227632 256448636 Rat 2293674 Bss39 Bone structure and strength QTL 39 7.1 0.0001 femur strength trait (VT:0010010) femur total energy absorbed before break (CMO:0001677) 1 201554356 246554356 Rat 2302378 Insul11 Insulin level QTL 11 3.25 blood insulin amount (VT:0001560) serum insulin level (CMO:0000358) 1 144267353 251128347 Rat 1354653 Despr9 Despair related QTL 9 0.00019 locomotor behavior trait (VT:0001392) amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958) 1 167909849 212909849 Rat 2293673 Bss27 Bone structure and strength QTL 27 18.63 0.0001 femur morphology trait (VT:0000559) femur midshaft cortical cross-sectional area (CMO:0001663) 1 171629477 216629477 Rat 2293677 Bss41 Bone structure and strength QTL 41 9.38 0.0001 lumbar vertebra size trait (VT:0010518) lumbar vertebra cross-sectional area (CMO:0001689) 1 171629477 216629477 Rat 1302787 Stl25 Serum triglyceride level QTL 25 2.7 0.0073 blood triglyceride amount (VT:0002644) plasma triglyceride level (CMO:0000548) 1 180359209 210702199 Rat 1549830 Bss1 Bone structure and strength QTL 1 4.8 femur strength trait (VT:0010010) femur ultimate force (CMO:0001675) 1 172609619 217609619 Rat 7794788 Mcs32 Mammary carcinoma susceptibility QTL 32 2.61 mammary gland integrity trait (VT:0010552) mammary tumor incidence/prevalence measurement (CMO:0000946) 1 115540693 238914717 Rat 70163 Bw20 Body weight QTL 20 5.1 body mass (VT:0001259) body weight (CMO:0000012) 1 174133260 219133260 Rat 1578763 Kidm29 Kidney mass QTL 29 3.3 0.0001 kidney mass (VT:0002707) both kidneys wet weight (CMO:0000085) 1 179567751 260522016 Rat 1600395 Niddm69 Non-insulin dependent diabetes mellitus QTL 69 4.14 0.0002 blood insulin amount (VT:0001560) plasma insulin level (CMO:0000342) 1 195804352 257091168 Rat 1354624 Cm35 Cardiac mass QTL35 5.7 heart left ventricle mass (VT:0007031) calculated heart weight (CMO:0000073) 1 177227632 256448636 Rat 1600396 Niddm68 Non-insulin dependent diabetes mellitus QTL 68 4.97 0.0003 blood glucose amount (VT:0000188) blood glucose level area under curve (AUC) (CMO:0000350) 1 195804352 257091168 Rat 1558658 Bw59 Body weight QTL 59 3.5 0.0003 body mass (VT:0001259) body weight (CMO:0000012) 1 178784622 223784622 Rat 631838 Niddm36 Non-insulin dependent diabetes mellitus QTL 36 0.01 insulin secretion trait (VT:0003564) calculated pancreatic islet insulin release measurement (CMO:0001217) 1 184550676 229550676 Rat 1549837 Hcar15 Hepatocarcinoma resistance QTL 15 0.05 liver integrity trait (VT:0010547) liver tumorous lesion number (CMO:0001068) 1 153136852 260522016 Rat 2293689 Bss47 Bone structure and strength QTL 47 7.25 0.0001 lumbar vertebra size trait (VT:0010518) lumbar vertebra trabecular cross-sectional area (CMO:0001692) 1 171629477 216629477 Rat 152025235 Bw194 Body weight QTL 194 4.86 body mass (VT:0001259) 1 123556856 242907031 Rat 1600388 Niddm67 Non-insulin dependent diabetes mellitus QTL 67 5.84 0.000004 blood glucose amount (VT:0000188) blood glucose level area under curve (AUC) (CMO:0000350) 1 195804352 257091168 Rat 2293694 Bss38 Bone structure and strength QTL 38 7.05 0.0001 femur strength trait (VT:0010010) femur stiffness (CMO:0001674) 1 201554356 246554356 Rat 1598853 Memor3 Memory QTL 3 4.5 exploratory behavior trait (VT:0010471) total horizontal distance resulting from voluntary locomotion in an experimental apparatus (CMO:0001443) 1 143506580 212458660 Rat 61341 Bp26 Blood pressure QTL 26 arterial blood pressure trait (VT:2000000) systolic blood pressure (CMO:0000004) 1 169537671 214537671 Rat 1578759 Uae30 Urinary albumin excretion QTL 30 3.3 0.003 urine albumin amount (VT:0002871) urine albumin excretion rate (CMO:0000757) 1 150700247 252085048 Rat 2293693 Bss22 Bone structure and strength QTL 22 33.52 0.0001 femur morphology trait (VT:0000559) femur cross-sectional area (CMO:0001661) 1 171629477 216629477 Rat 2300161 Bmd43 Bone mineral density QTL 43 8.4 0.0001 femur mineral mass (VT:0010011) volumetric bone mineral density (CMO:0001553) 1 171629477 216629477 Rat 1300145 Rf7 Renal function QTL 7 2.96 urine creatinine amount (VT:0010540) urine creatinine level (CMO:0000125) 1 185145134 221264292 Rat 61347 Bp197 Blood pressure QTL 197 4.2 arterial blood pressure trait (VT:2000000) blood pressure measurement (CMO:0000003) 1 158633083 203633083 Rat 8655655 Arrd2 Age-related retinal degeneration QTL 2 7.79 retinal layer morphology trait (VT:0003727) percentage of study population developing retinopathy during a period of time (CMO:0002453) 1 183970203 243914901 Rat 1358898 Bp255 Blood pressure QTL 255 3.6 arterial blood pressure trait (VT:2000000) mean arterial blood pressure (CMO:0000009) 1 191019702 246062233 Rat 631214 Bw61 Body weight QTL61 3.4 0.0001 intramuscular adipose amount (VT:0010044) intramuscular fat area (CMO:0001162) 1 173108781 218108781 Rat 7771612 Cm80 Cardiac mass QTL 80 8.4 heart left ventricle mass (VT:0007031) heart left ventricle weight (CMO:0000776) 1 149448574 221264292 Rat 731168 Bp154 Blood pressure QTL 154 3.4 arterial blood pressure trait (VT:2000000) systolic blood pressure (CMO:0000004) 1 94642644 214537671 Rat 2300175 Bmd40 Bone mineral density QTL 40 15.4 0.0001 femur mineral mass (VT:0010011) bone mineral density (CMO:0001226) 1 201554356 246554356 Rat 2300174 Bmd42 Bone mineral density QTL 42 8.4 0.0001 lumbar vertebra mineral mass (VT:0010511) bone mineral density (CMO:0001226) 1 171629477 216629477 Rat 737828 Hcas3 Hepatocarcinoma susceptibility QTL 3 4.9 liver integrity trait (VT:0010547) liver tumorous lesion volume to total liver volume ratio (CMO:0001082) 1 144267353 222987745 Rat 1354661 Bw33 Body weight QTL 33 5.2 body mass (VT:0001259) body weight (CMO:0000012) 1 151162512 256448636 Rat 1358886 Bp260 Blood pressure QTL 260 3.67 arterial blood pressure trait (VT:2000000) mean arterial blood pressure (CMO:0000009) 1 151162766 225824951 Rat 737977 Bp160 Blood pressure QTL 160 0.001 arterial blood pressure trait (VT:2000000) mean arterial blood pressure (CMO:0000009) 1 181133855 226133855 Rat 2293654 Bss30 Bone structure and strength QTL 30 32.65 0.0001 femur strength trait (VT:0010010) femur midshaft polar moment of inertia (CMO:0001669) 1 171629477 216629477 Rat 2293655 Bss36 Bone structure and strength QTL 36 10.66 0.0001 femur strength trait (VT:0010010) femur ultimate force (CMO:0001675) 1 201554356 246554356 Rat 1298084 Thym4 Thymus enlargement QTL 4 10.68 thymus mass (VT:0004954) thymus weight to body weight ratio (CMO:0000612) 1 197814409 242814409 Rat 724531 Uae5 Urinary albumin excretion QTL 5 4 urine albumin amount (VT:0002871) urine albumin level (CMO:0000130) 1 150700142 252085212 Rat 2300187 Bmd41 Bone mineral density QTL 41 8.9 0.0001 femur mineral mass (VT:0010011) volumetric bone mineral density (CMO:0001553) 1 171629477 216629477 Rat 8552891 Epfw5 Epididymal fat weight QTL 5 4.4 epididymal fat pad mass (VT:0010421) epididymal fat pad weight to body weight ratio (CMO:0000658) 1 193113876 238113876 Rat 1354580 Scort1 Serum corticosterone level QTL 1 3.4 blood corticosterone amount (VT:0005345) blood corticosterone level (CMO:0001172) 1 156677124 256448636 Rat 1358292 Cm37 Cardiac mass QTL 37 6.2 8e-07 heart mass (VT:0007028) heart weight to body weight ratio (CMO:0000074) 1 196248093 241248093 Rat 61376 Bp42 Blood pressure QTL 42 23.4 arterial blood pressure trait (VT:2000000) systolic blood pressure (CMO:0000004) 1 197814409 242814409 Rat 634313 Niddm43 Non-insulin dependent diabetes mellitus QTL 43 blood glucose amount (VT:0000188) blood glucose level (CMO:0000046) 1 199050459 259647894 Rat 634312 Bp143 Blood pressure QTL 143 3 0.0002 arterial blood pressure trait (VT:2000000) systolic blood pressure (CMO:0000004) 1 182623426 219932796 Rat 1358294 Bw37 Body weight QTL 37 5 0.000011 body mass (VT:0001259) body weight (CMO:0000012) 1 171310381 216310381 Rat 724559 Pancm1 Pancreatic morphology QTL 1 7.1 islet of Langerhans morphology trait (VT:0005215) pancreatic islet damage composite score (CMO:0001156) 1 181759564 214537555 Rat 2312420 Pur17 Proteinuria QTL 17 7.1 0.0001 urine protein amount (VT:0005160) urine total protein excretion rate (CMO:0000756) 1 156677124 218753816 Rat 10059600 Bp378 Blood pressure QTL 378 3.08 0.05 arterial blood pressure trait (VT:2000000) systolic blood pressure (CMO:0000004) 1 176869060 221869060 Rat 7421630 Bp362 Blood pressure QTL 362 0.001 arterial blood pressure trait (VT:2000000) mean arterial blood pressure (CMO:0000009) 1 118608292 241799120 Rat 619613 Bp77 Blood pressure QTL 77 0.01 arterial blood pressure trait (VT:2000000) diastolic blood pressure (CMO:0000005) 1 164747424 209747424 Rat 2312564 Glom18 Glomerulus QTL 18 2.4 0.003 kidney glomerulus morphology trait (VT:0005325) index of glomerular damage (CMO:0001135) 1 185356336 231689108 Rat 634321 Hc1 Hypercalciuria QTL 1 2.91 urine calcium amount (VT:0002985) urine calcium excretion rate (CMO:0000763) 1 178810256 240830002 Rat 2292218 Kidm35 Kidney mass QTL 35 kidney mass (VT:0002707) both kidneys wet weight to body weight ratio (CMO:0000340) 1 199368955 224569684 Rat 724562 Rends1 Renal damage susceptibility QTL 1 0.05 kidney glomerulus integrity trait (VT:0010546) index of glomerular damage (CMO:0001135) 1 169537671 214537671 Rat 1331790 Bp201 Blood pressure QTL 201 3.127 arterial blood pressure trait (VT:2000000) mean arterial blood pressure (CMO:0000009) 1 198211513 225126682 Rat 10059587 Bw173 Body weight QTL 173 3.23 0.025 body mass (VT:0001259) body weight (CMO:0000012) 1 202069611 247069611 Rat 2292222 Bp307 Blood pressure QTL 307 3.06 0.0014 arterial blood pressure trait (VT:2000000) systolic blood pressure (CMO:0000004) 1 164310393 213533942 Rat 2292220 Bp306 Blood pressure QTL 306 3.47 0.00087 arterial blood pressure trait (VT:2000000) systolic blood pressure (CMO:0000004) 1 164310393 243914901 Rat 10059590 Kidm44 Kidney mass QTL 44 3.42 0.025 kidney mass (VT:0002707) both kidneys wet weight to body weight ratio (CMO:0000340) 1 191033875 236033875 Rat 1641926 Teswt2 Testicular weight QTL 2 2.82 testis mass (VT:1000644) both testes wet weight (CMO:0000175) 1 197697768 238755659 Rat 631658 Cm7 Cardiac mass QTL 7 5.32 0.0001 aorta mass (VT:0002845) aorta weight (CMO:0000076) 1 196248093 241248093 Rat 1600380 Niddm70 Non-insulin dependent diabetes mellitus QTL 70 3.1 0.0008 blood insulin amount (VT:0001560) plasma insulin level (CMO:0000342) 1 176550523 221550523 Rat 1354610 Bw34 Body weight QTL 34 4.1 body mass (VT:0001259) body weight (CMO:0000012) 1 151162512 256448636 Rat 1582206 Kidm33 Kidney mass QTL 33 6.9 kidney mass (VT:0002707) both kidneys wet weight to body weight ratio (CMO:0000340) 1 188377360 224054420 Rat 8655855 Arrd3 Age-related retinal degeneration QTL 3 3.07 lens clarity trait (VT:0001304) cataract incidence/prevalence measurement (CMO:0001585) 1 183970203 243914901 Rat 634338 Hcar4 Hepatocarcinoma resistance QTL 4 4.6 liver integrity trait (VT:0010547) liver tumorous lesion number to liver area ratio (CMO:0001210) 1 193422268 214537671 Rat 6903303 Scl34 Serum cholesterol QTL 34 2.5 0.0033 blood cholesterol amount (VT:0000180) plasma total cholesterol level (CMO:0000585) 1 180359209 218108781 Rat 1600374 Mcs17 Mammary carcinoma susceptibility QTL 17 3 mammary gland integrity trait (VT:0010552) mammary tumor number (CMO:0000343) 1 197670404 242670404 Rat 2293083 Iddm25 Insulin dependent diabetes mellitus QTL 25 4.18 blood glucose amount (VT:0000188) blood glucose level (CMO:0000046) 1 181829673 224569684 Rat 1354606 Bp246 Blood pressure QTL 246 3.6 arterial blood pressure trait (VT:2000000) pulse pressure (CMO:0000292) 1 102813953 218753816 Rat 738032 Hcas5 Hepatocarcinoma susceptibility QTL 5 3.12 liver integrity trait (VT:0010547) liver tumorous lesion number (CMO:0001068) 1 176426412 257976495 Rat 1358191 Ept10 Estrogen-induced pituitary tumorigenesis QTL 10 3.8 pituitary gland mass (VT:0010496) pituitary gland wet weight (CMO:0000853) 1 192825253 243914732 Rat 7394701 Uae46 Urinary albumin excretion QTL 46 3.6 0.0056 urine albumin amount (VT:0002871) urine albumin excretion rate (CMO:0000757) 1 201554356 246554356 Rat
RH132473
Rat Assembly Chr Position (strand) Source JBrowse mRatBN7.2 1 203,227,310 - 203,227,517 (+) MAPPER mRatBN7.2 Rnor_6.0 1 221,297,545 - 221,297,751 NCBI Rnor6.0 Rnor_5.0 1 228,231,994 - 228,232,200 UniSTS Rnor5.0 RGSC_v3.4 1 208,573,281 - 208,573,487 UniSTS RGSC3.4 Celera 1 200,761,997 - 200,762,203 UniSTS RH 3.4 Map 1 1538.8 UniSTS Cytogenetic Map 1 q43 UniSTS
BE098956
Rat Assembly Chr Position (strand) Source JBrowse mRatBN7.2 1 203,231,371 - 203,231,549 (+) MAPPER mRatBN7.2 Rnor_6.0 1 221,301,606 - 221,301,783 NCBI Rnor6.0 Rnor_5.0 1 228,236,055 - 228,236,232 UniSTS Rnor5.0 RGSC_v3.4 1 208,577,342 - 208,577,519 UniSTS RGSC3.4 Celera 1 200,766,059 - 200,766,236 UniSTS RH 3.4 Map 1 1530.5 UniSTS Cytogenetic Map 1 q43 UniSTS
AI008924
Rat Assembly Chr Position (strand) Source JBrowse mRatBN7.2 1 203,231,129 - 203,231,315 (+) MAPPER mRatBN7.2 Rnor_6.0 1 221,301,364 - 221,301,549 NCBI Rnor6.0 Rnor_5.0 1 228,235,813 - 228,235,998 UniSTS Rnor5.0 RGSC_v3.4 1 208,577,100 - 208,577,285 UniSTS RGSC3.4 Celera 1 200,765,817 - 200,766,002 UniSTS RH 3.4 Map 1 1534.7 UniSTS Cytogenetic Map 1 q43 UniSTS
Click on a value in the shaded box below the category label to view a detailed expression data table for that system.
alimentary part of gastrointestinal system
9
11
49
113
91
90
59
25
59
6
218
97
93
45
60
31
Too many to show, limit is 500. Download them if you would like to view them all.
Ensembl Acc Id:
ENSRNOT00000028406 ⟹ ENSRNOP00000028406
Type:
CODING
Position:
Rat Assembly Chr Position (strand) Source mRatBN7.2 Ensembl 1 203,227,190 - 203,251,348 (-) Ensembl Rnor_6.0 Ensembl 1 221,297,418 - 221,321,459 (-) Ensembl
Ensembl Acc Id:
ENSRNOT00000084800 ⟹ ENSRNOP00000073312
Type:
CODING
Position:
Rat Assembly Chr Position (strand) Source mRatBN7.2 Ensembl 1 203,203,388 - 203,251,348 (-) Ensembl Rnor_6.0 Ensembl 1 221,273,538 - 221,321,570 (-) Ensembl
Ensembl Acc Id:
ENSRNOT00000115121 ⟹ ENSRNOP00000097329
Type:
CODING
Position:
Rat Assembly Chr Position (strand) Source mRatBN7.2 Ensembl 1 203,227,190 - 203,251,348 (-) Ensembl
RefSeq Acc Id:
NM_053480 ⟹ NP_445932
RefSeq Status:
PROVISIONAL
Type:
CODING
Position:
Rat Assembly Chr Position (strand) Source GRCr8 1 212,656,500 - 212,680,542 (-) NCBI mRatBN7.2 1 203,227,183 - 203,251,225 (-) NCBI Rnor_6.0 1 221,297,417 - 221,321,459 (-) NCBI Rnor_5.0 1 228,231,866 - 228,255,908 (-) NCBI RGSC_v3.4 1 208,573,153 - 208,597,195 (-) RGD Celera 1 200,761,869 - 200,785,913 (-) RGD
Sequence:
GTTGGGGTCGTCTGAGGGCTTAGGCCAGGTGGTCTTGTGACCGGTCCCTGTCACCTTCCCACAAAGTGAAAGAATAAGCCTCTGCCGGGCAGATTTGAGCTGAAGTCGGAGCCCTGCGGCAGGCTCCC
hide sequence
RefSeq Acc Id:
XM_039092900 ⟹ XP_038948828
Type:
CODING
Position:
Rat Assembly Chr Position (strand) Source GRCr8 1 212,659,779 - 212,680,667 (-) NCBI mRatBN7.2 1 203,230,478 - 203,251,349 (-) NCBI
RefSeq Acc Id:
XM_039092904 ⟹ XP_038948832
Type:
CODING
Position:
Rat Assembly Chr Position (strand) Source GRCr8 1 212,656,510 - 212,668,823 (-) NCBI mRatBN7.2 1 203,227,187 - 203,239,508 (-) NCBI
RefSeq Acc Id:
XM_063275875 ⟹ XP_063131945
Type:
CODING
Position:
Rat Assembly Chr Position (strand) Source GRCr8 1 212,658,273 - 212,680,667 (-) NCBI
RefSeq Acc Id:
XM_063275884 ⟹ XP_063131954
Type:
CODING
Position:
Rat Assembly Chr Position (strand) Source GRCr8 1 212,658,273 - 212,680,667 (-) NCBI
RefSeq Acc Id:
XR_001835495
Type:
NON-CODING
Position:
Rat Assembly Chr Position (strand) Source GRCr8 1 212,657,949 - 212,680,667 (-) NCBI mRatBN7.2 1 203,228,651 - 203,251,349 (-) NCBI Rnor_6.0 1 221,299,190 - 221,321,601 (-) NCBI
Sequence:
CGGGGTTGAGCCGGACCTCGCGCAAGCGCGCGCTAGGCAAAGCGTTTGGCGGGTTTTTCCTGGCTGTAGCATTCGGAAGCAAGTTTTCTCTCCGGATCGAGACCTCTCGAGGGTTGTTGAAGTATTTC
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RefSeq Acc Id:
XR_005493528
Type:
NON-CODING
Position:
Rat Assembly Chr Position (strand) Source GRCr8 1 212,658,497 - 212,680,667 (-) NCBI mRatBN7.2 1 203,227,186 - 203,251,349 (-) NCBI
RefSeq Acc Id:
XR_005493542
Type:
NON-CODING
Position:
Rat Assembly Chr Position (strand) Source GRCr8 1 212,658,273 - 212,680,667 (-) NCBI mRatBN7.2 1 203,227,186 - 203,251,350 (-) NCBI
RefSeq Acc Id:
XR_010058450
Type:
NON-CODING
Position:
Rat Assembly Chr Position (strand) Source GRCr8 1 212,657,949 - 212,680,667 (-) NCBI
RefSeq Acc Id:
NP_445932 ⟸ NM_053480
- UniProtKB:
Q4V8M9 (UniProtKB/TrEMBL), A6HZB5 (UniProtKB/TrEMBL), G3V8U6 (UniProtKB/TrEMBL)
- Sequence:
MAVSTQQLAEELQIFGLDCEDSLLEKLAELCTLYRQTEERMVSELIAFCTSAGKSCLTGEILSSFEHEVLNKKLSKACHSASKDNRHAGARDIVSIQELIEAEEEEETLLSAYTTPSKGPHKRVSSTP
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Ensembl Acc Id:
ENSRNOP00000073312 ⟸ ENSRNOT00000084800
Ensembl Acc Id:
ENSRNOP00000028406 ⟸ ENSRNOT00000028406
RefSeq Acc Id:
XP_038948832 ⟸ XM_039092904
- Peptide Label:
isoform X4
RefSeq Acc Id:
XP_038948828 ⟸ XM_039092900
- Peptide Label:
isoform X3
Ensembl Acc Id:
ENSRNOP00000097329 ⟸ ENSRNOT00000115121
RefSeq Acc Id:
XP_063131954 ⟸ XM_063275884
- Peptide Label:
isoform X2
RefSeq Acc Id:
XP_063131945 ⟸ XM_063275875
- Peptide Label:
isoform X1
- UniProtKB:
A0A0G2K567 (UniProtKB/TrEMBL)
RGD ID: 13690676 Promoter ID: EPDNEW_R1201 Type: multiple initiation site Name: Pola2_1 Description: DNA polymerase alpha 2, accessory subunit SO ACC ID: SO:0000170 Source: EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/ ) Experiment Methods: Single-end sequencing. Position: Rat Assembly Chr Position (strand) Source Rnor_6.0 1 221,321,531 - 221,321,591 EPDNEW
Date
Current Symbol
Current Name
Previous Symbol
Previous Name
Description
Reference
Status
2016-07-21
Pola2
DNA polymerase alpha 2, accessory subunit
Pola2
polymerase (DNA) alpha 2, accessory subunit
Nomenclature updated to reflect human and mouse nomenclature
1299863 APPROVED
2016-03-16
Pola2
polymerase (DNA) alpha 2, accessory subunit
Pola2
polymerase (DNA directed), alpha 2, accessory subunit
Nomenclature updated to reflect human and mouse nomenclature
1299863 APPROVED
2013-02-27
Pola2
polymerase (DNA directed), alpha 2, accessory subunit
Pola2
polymerase (DNA directed), alpha 2
Nomenclature updated to reflect human and mouse nomenclature
1299863 APPROVED
2005-01-20
Pola2
polymerase (DNA directed), alpha 2
DNA polymerase alpha subunit II
Name updated
1299863 APPROVED
2002-08-07
Pola2
DNA polymerase alpha subunit II
Symbol and Name status set to provisional
70820 PROVISIONAL
