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Gene: Pola2 (polymerase (DNA directed), alpha 2) Mus musculus
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Symbol: Pola2
Name: polymerase (DNA directed), alpha 2
Description: Exhibits protein heterodimerization activity. Involved in DNA replication and protein import into nucleus. Localizes to the alpha DNA polymerase:primase complex. Is expressed in several structures, including alimentary system; brain; genitourinary system; integumental system; and sensory organ. Orthologous to human POLA2 (DNA polymerase alpha 2, accessory subunit); PARTICIPATES IN DNA replication pathway; purine metabolic pathway; pyrimidine metabolic pathway; INTERACTS WITH 2,2',4,4',5,5'-hexachlorobiphenyl; 2,2',5,5'-tetrachlorobiphenyl; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: AI573378; DNA polymerase alpha 2, 68 kDa; DNA polymerase alpha 70 kDa subunit; DNA polymerase alpha subunit B
Orthologs:
Homo sapiens (human) : POLA2 (DNA polymerase alpha 2, accessory subunit)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Pola2 (DNA polymerase alpha 2, accessory subunit)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Pola2 (DNA polymerase alpha 2, accessory subunit)
Pan paniscus (bonobo/pygmy chimpanzee) : POLA2 (DNA polymerase alpha 2, accessory subunit)
Canis lupus familiaris (dog) : POLA2 (DNA polymerase alpha 2, accessory subunit)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Pola2 (DNA polymerase alpha 2, accessory subunit)
Sus scrofa (pig) : POLA2 (DNA polymerase alpha 2, accessory subunit)
Chlorocebus sabaeus (green monkey) : POLA2 (DNA polymerase alpha 2, accessory subunit)
Heterocephalus glaber (naked mole-rat) : Pola2 (DNA polymerase alpha 2, accessory subunit)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38 Ensembl195,940,542 - 5,964,202 (-)Ensembl
GRCm38195,940,543 - 5,964,238 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37195,940,543 - 5,964,206 (-)NCBIGRCm37mm9NCBIm37
MGSCv36195,940,546 - 5,964,170 (-)NCBImm8
Celera195,810,597 - 5,834,275 (-)NCBICelera
Cytogenetic Map19 ANCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Pola2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 731624
Created: 2004-01-12
Species: Mus musculus
Last Modified: 2019-11-27
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.