Gna14 (G protein subunit alpha 14)

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Gene: Gna14 (G protein subunit alpha 14) Rattus norvegicus

Analyze

Symbol:

Gna14

Name:

G protein subunit alpha 14

RGD ID:

1308122

Description:

Predicted to enable G protein-coupled receptor binding activity; G-protein beta/gamma-subunit complex binding activity; and GTPase activity. Predicted to be involved in action potential; adenylate cyclase-modulating G protein-coupled receptor signaling pathway; and phospholipase C-activating dopamine receptor signaling pathway. Predicted to be part of heterotrimeric G-protein complex. Orthologous to human GNA14 (G protein subunit alpha 14); PARTICIPATES IN acetylcholine signaling pathway via muscarinic acetylcholine receptors engaging G alphaq protein family; eicosanoid signaling pathway; endothelin signaling pathway; INTERACTS WITH 1,3-dinitrobenzene; 1-naphthyl isothiocyanate; 17beta-estradiol.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

guanine nucleotide binding protein, alpha 14; guanine nucleotide-binding protein subunit alpha-14; heterotrimeric guanine nucleotide-binding protein 1i; Hg1i; LOC309242; MGC105546; TGFB inducible early growth response 3; Tieg3

RGD Orthologs

Human

Mouse

Chinchilla

Bonobo

Dog

Squirrel

Pig

Green Monkey

Naked Mole-Rat

Alliance Genes

More Info

more info ...

Latest Assembly:

mRatBN7.2 - mRatBN7.2 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mRatBN7.2	1	213,714,993 - 213,900,083 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	1	213,716,020 - 213,897,423 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	1	222,045,687 - 222,225,954 (+)	NCBI	Rnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.0	1	228,978,868 - 229,161,277 (+)	NCBI	Rnor_SHRSP
UTH_Rnor_WKY_Bbb_1.0	1	221,800,246 - 221,980,512 (+)	NCBI	Rnor_WKY
Rnor_6.0	1	235,165,775 - 235,347,986 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	1	235,166,718 - 235,347,937 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	1	242,484,562 - 242,665,783 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	1	219,906,120 - 219,983,252 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
Celera	1	211,049,903 - 211,230,953 (+)	NCBI		Celera
Cytogenetic Map	1	q43	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

choreaacanthocytosis (ISO)

Experimental Liver Cirrhosis (ISO)

genetic disease (ISO)

High Myopia (ISO)

Kaposiform Hemangioendothelioma (ISO)

Neu-Laxova syndrome 2 (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

1,1-dichloroethene (ISO)

1,2-dimethylhydrazine (ISO)

1,3-dinitrobenzene (EXP)

1-naphthyl isothiocyanate (EXP)

17alpha-ethynylestradiol (ISO)

17beta-estradiol (EXP)

2,3',4,4',5-Pentachlorobiphenyl (ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

3,3',4,4',5-pentachlorobiphenyl (EXP)

3-Chloro-4-(dichloromethyl)-5-hydroxy-2(5H)-furanone (ISO)

4,4'-diaminodiphenylmethane (EXP)

4,4'-sulfonyldiphenol (ISO)

6-propyl-2-thiouracil (EXP)

acrylamide (EXP)

aflatoxin B1 (EXP,ISO)

arsenite(3-) (ISO)

atrazine (EXP)

beauvericin (ISO)

benzo[a]pyrene (EXP,ISO)

benzo[b]fluoranthene (ISO)

bis(2-ethylhexyl) phthalate (ISO)

bisphenol A (EXP,ISO)

bisphenol F (ISO)

carbamazepine (ISO)

carbon nanotube (ISO)

cefaloridine (EXP)

CGP 52608 (ISO)

chlorpyrifos (EXP)

choline (ISO)

cisplatin (EXP)

cobalt dichloride (EXP)

copper atom (EXP)

copper(0) (EXP)

Cuprizon (EXP)

cyanocob(III)alamin (ISO)

dextran sulfate (ISO)

diazinon (EXP)

dibenz[a,h]anthracene (ISO)

dibutyl phthalate (ISO)

dichloroacetic acid (ISO)

dioxygen (ISO)

dorsomorphin (ISO)

endosulfan (EXP)

enniatin (ISO)

ethanol (EXP)

fenvalerate (EXP)

folic acid (ISO)

furan (EXP)

glycine betaine (ISO)

GW 4064 (ISO)

hexane (EXP)

L-methionine (ISO)

mercury dibromide (ISO)

N-nitrosodimethylamine (EXP)

nickel atom (ISO)

nitrofen (EXP)

orphenadrine (EXP)

paracetamol (EXP,ISO)

paraquat (EXP)

permethrin (EXP)

phenobarbital (ISO)

phenylmercury acetate (ISO)

pirinixic acid (ISO)

rotenone (ISO)

SB 431542 (ISO)

silicon dioxide (ISO)

sodium arsenite (ISO)

sodium dichromate (EXP)

Soman (EXP)

tetrachloromethane (ISO)

titanium dioxide (ISO)

triadimefon (ISO)

trichloroethene (ISO)

triphenyl phosphate (EXP)

valproic acid (EXP,ISO)

zinc atom (ISO)

zinc(0) (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

action potential (IBA)

adenylate cyclase-modulating G protein-coupled receptor signaling pathway (IBA)

biological_process (ND)

phospholipase C-activating dopamine receptor signaling pathway (IBA)

Cellular Component

cellular_component (ND)

heterotrimeric G-protein complex (IBA)

Molecular Function

G protein-coupled receptor binding (IBA)

G-protein beta/gamma-subunit complex binding (IBA)

GTP binding (IEA)

GTPase activity (IBA)

molecular_function (ND)

protein binding (ISO)

Molecular Pathway Annotations Click to see Annotation Detail View

acetylcholine signaling pathway via muscarinic acetylcholine receptors engaging G alphaq protein family (ISO)

calcium/calcium-mediated signaling pathway (IEA)

Chagas disease pathway (IEA)

eicosanoid signaling pathway (ISO)

endothelin signaling pathway (ISO)

Entamoebiasis pathway (IEA)

G protein mediated signaling pathway via Galphaq family (ISO)

sphingosine 1-phosphate signaling pathway (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	Rat ISS GO annotations from GOA human gene data--August 2006	GOA data from the GO Consortium
3.	Molecular properties of muscarinic acetylcholine receptors.	Haga T Proc Jpn Acad Ser B Phys Biol Sci. 2013;89(6):226-56.
4.	Rat ISS GO annotations from MGI mouse gene data--August 2006	MGD data from the GO Consortium
5.	KEGG Annotation Import Pipeline	Pipeline to import KEGG annotations from KEGG into RGD
6.	PID Annotation Import Pipeline	Pipeline to import Pathway Interaction Database annotations from NCI into RGD
7.	GOA pipeline	RGD automated data pipeline
8.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
9.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
10.	Comprehensive gene review and curation	RGD comprehensive gene curation
11.	Regulation of phosphoinositide-specific phospholipase C.	Rhee SG Annu Rev Biochem. 2001;70:281-312.
12.	Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.	Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.

Additional References at PubMed

PMID:23533145

Genomics

Comparative Map Data

Gna14
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mRatBN7.2	1	213,714,993 - 213,900,083 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	1	213,716,020 - 213,897,423 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	1	222,045,687 - 222,225,954 (+)	NCBI	Rnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.0	1	228,978,868 - 229,161,277 (+)	NCBI	Rnor_SHRSP
UTH_Rnor_WKY_Bbb_1.0	1	221,800,246 - 221,980,512 (+)	NCBI	Rnor_WKY
Rnor_6.0	1	235,165,775 - 235,347,986 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	1	235,166,718 - 235,347,937 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	1	242,484,562 - 242,665,783 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	1	219,906,120 - 219,983,252 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
Celera	1	211,049,903 - 211,230,953 (+)	NCBI		Celera
Cytogenetic Map	1	q43	NCBI

GNA14
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	9	77,423,079 - 77,648,322 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p13 Ensembl	9	77,423,079 - 77,648,322 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	9	80,037,995 - 80,263,238 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	9	79,228,368 - 79,453,043 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	9	77,268,102 - 77,492,777	NCBI
Celera	9	50,615,129 - 50,840,361 (-)	NCBI		Celera
Cytogenetic Map	9	q21.2	NCBI
HuRef	9	49,869,436 - 50,095,508 (-)	NCBI		HuRef
CHM1_1	9	80,184,787 - 80,410,463 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	9	89,579,647 - 89,805,301 (-)	NCBI		T2T-CHM13v2.0

Gna14
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	19	16,413,031 - 16,590,706 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	19	16,413,126 - 16,588,184 (+)	Ensembl		GRCm39 Ensembl
GRCm38	19	16,435,667 - 16,610,818 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	19	16,435,762 - 16,610,820 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	19	16,510,157 - 16,685,308 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	19	16,502,781 - 16,677,839 (+)	NCBI		MGSCv36	mm8
Celera	19	17,094,438 - 17,269,681 (+)	NCBI		Celera
Cytogenetic Map	19	A	NCBI
cM Map	19	11.29	NCBI

Gna14
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955512	1,707,503 - 1,917,513 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955512	1,703,750 - 1,918,321 (+)	NCBI	ChiLan1.0	ChiLan1.0

LOC100987065
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
PanPan1.1	9	76,276,687 - 76,504,137 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
Mhudiblu_PPA_v0	9	47,196,338 - 47,423,388 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3

GNA14
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	1	80,992,992 - 81,178,362 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	1	80,992,863 - 81,177,674 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	1	81,455,728 - 81,642,025 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	1	81,404,645 - 81,590,940 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	1	81,405,467 - 81,590,428 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	1	81,190,051 - 81,376,315 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	1	80,911,720 - 81,098,022 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	1	81,641,964 - 81,827,205 (+)	NCBI		UU_Cfam_GSD_1.0

LOC101971412
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404947	128,116,262 - 128,313,527 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936503	12,859,715 - 13,056,244 (-)	Ensembl	SpeTri2.0
SpeTri2.0	NW_004936503	12,860,296 - 13,056,880 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

GNA14
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	1	230,341,942 - 230,546,120 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	1	230,341,947 - 230,545,123 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	1	257,105,693 - 257,310,461 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

GNA14
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	12	88,386,597 - 88,606,787 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	12	88,385,377 - 88,605,845 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666038	76,717,968 - 76,939,040 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Gna14
(Heterocephalus glaber - naked mole-rat)

Naked Mole-rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624811	4,909,324 - 5,108,322 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624811	4,904,428 - 5,108,713 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in Gna14
1141 total Variants

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	500
Count of miRNA genes:	238
Interacting mature miRNAs:	288
Transcripts:	ENSRNOT00000020201
Prediction methods:	Microtar, Miranda, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (mRatBN7.2)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
1578780	Cm52	Cardiac mass QTL 52	3.3	0.0001	heart mass (VT:0007028)	heart wet weight (CMO:0000069)	1	81591954	219808434	Rat
731168	Bp154	Blood pressure QTL 154	3.4		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	94642722	214537671	Rat
1354606	Bp246	Blood pressure QTL 246	3.6		arterial blood pressure trait (VT:2000000)	pulse pressure (CMO:0000292)	1	102813953	218753816	Rat
7794788	Mcs32	Mammary carcinoma susceptibility QTL 32	2.61		mammary gland integrity trait (VT:0010552)	mammary tumor incidence/prevalence measurement (CMO:0000946)	1	115540693	238914717	Rat
7421630	Bp362	Blood pressure QTL 362		0.001	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	1	118608292	241799120	Rat
737828	Hcas3	Hepatocarcinoma susceptibility QTL 3	4.9		liver integrity trait (VT:0010547)	liver tumorous lesion volume to total liver volume ratio (CMO:0001082)	1	144267353	222987745	Rat
2302378	Insul11	Insulin level QTL 11	3.25		blood insulin amount (VT:0001560)	serum insulin level (CMO:0000358)	1	144267353	251128347	Rat
7771612	Cm80	Cardiac mass QTL 80	8.4		heart left ventricle mass (VT:0007031)	heart left ventricle weight (CMO:0000776)	1	149448574	221264292	Rat
724531	Uae5	Urinary albumin excretion QTL 5	4		urine albumin amount (VT:0002871)	urine albumin level (CMO:0000130)	1	150700142	252085212	Rat
1578759	Uae30	Urinary albumin excretion QTL 30	3.3	0.003	urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	1	150700247	252085048	Rat
1578778	Pur4	Proteinuria QTL 4	3.3	0.003	urine total protein amount (VT:0000032)	urine total protein excretion rate (CMO:0000756)	1	150700247	252085048	Rat
1354610	Bw34	Body weight QTL 34	4.1		body mass (VT:0001259)	body weight (CMO:0000012)	1	151162512	256448636	Rat
1354646	Kidm18	Kidney mass QTL 18	5.7		kidney mass (VT:0002707)	calculated kidney weight (CMO:0000160)	1	151162512	256448636	Rat
1354661	Bw33	Body weight QTL 33	5.2		body mass (VT:0001259)	body weight (CMO:0000012)	1	151162512	256448636	Rat
1358886	Bp260	Blood pressure QTL 260	3.67		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	1	151162766	225824951	Rat
1549837	Hcar15	Hepatocarcinoma resistance QTL 15		0.05	liver integrity trait (VT:0010547)	liver tumorous lesion number (CMO:0001068)	1	153136852	260522016	Rat
2312420	Pur17	Proteinuria QTL 17	7.1	0.0001	urine protein amount (VT:0005160)	urine total protein excretion rate (CMO:0000756)	1	156677124	218753816	Rat
1354580	Scort1	Serum corticosterone level QTL 1	3.4		blood corticosterone amount (VT:0005345)	blood corticosterone level (CMO:0001172)	1	156677124	256448636	Rat
2292220	Bp306	Blood pressure QTL 306	3.47	0.00087	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	164310393	243914901	Rat
61341	Bp26	Blood pressure QTL 26			arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	169537671	214537671	Rat
724562	Rends1	Renal damage susceptibility QTL 1		0.05	kidney glomerulus integrity trait (VT:0010546)	index of glomerular damage (CMO:0001135)	1	169537671	214537671	Rat
1358294	Bw37	Body weight QTL 37	5	0.000011	body mass (VT:0001259)	body weight (CMO:0000012)	1	171310381	216310381	Rat
2293689	Bss47	Bone structure and strength QTL 47	7.25	0.0001	lumbar vertebra size trait (VT:0010518)	lumbar vertebra trabecular cross-sectional area (CMO:0001692)	1	171629477	216629477	Rat
2293693	Bss22	Bone structure and strength QTL 22	33.52	0.0001	femur morphology trait (VT:0000559)	femur cross-sectional area (CMO:0001661)	1	171629477	216629477	Rat
2300161	Bmd43	Bone mineral density QTL 43	8.4	0.0001	femur mineral mass (VT:0010011)	volumetric bone mineral density (CMO:0001553)	1	171629477	216629477	Rat
2300174	Bmd42	Bone mineral density QTL 42	8.4	0.0001	lumbar vertebra mineral mass (VT:0010511)	bone mineral density (CMO:0001226)	1	171629477	216629477	Rat
2300187	Bmd41	Bone mineral density QTL 41	8.9	0.0001	femur mineral mass (VT:0010011)	volumetric bone mineral density (CMO:0001553)	1	171629477	216629477	Rat
2293654	Bss30	Bone structure and strength QTL 30	32.65	0.0001	femur strength trait (VT:0010010)	femur midshaft polar moment of inertia (CMO:0001669)	1	171629477	216629477	Rat
2293673	Bss27	Bone structure and strength QTL 27	18.63	0.0001	femur morphology trait (VT:0000559)	femur midshaft cortical cross-sectional area (CMO:0001663)	1	171629477	216629477	Rat
2293677	Bss41	Bone structure and strength QTL 41	9.38	0.0001	lumbar vertebra size trait (VT:0010518)	lumbar vertebra cross-sectional area (CMO:0001689)	1	171629477	216629477	Rat
1549830	Bss1	Bone structure and strength QTL 1	4.8		femur strength trait (VT:0010010)	femur ultimate force (CMO:0001675)	1	172609619	217609619	Rat
631214	Bw61	Body weight QTL61	3.4	0.0001	intramuscular adipose amount (VT:0010044)	intramuscular fat area (CMO:0001162)	1	173108781	218108781	Rat
70163	Bw20	Body weight QTL 20	5.1		body mass (VT:0001259)	body weight (CMO:0000012)	1	174133260	219133260	Rat
738032	Hcas5	Hepatocarcinoma susceptibility QTL 5	3.12		liver integrity trait (VT:0010547)	liver tumorous lesion number (CMO:0001068)	1	176426412	257976495	Rat
1600380	Niddm70	Non-insulin dependent diabetes mellitus QTL 70	3.1	0.0008	blood insulin amount (VT:0001560)	plasma insulin level (CMO:0000342)	1	176550523	221550523	Rat
10059600	Bp378	Blood pressure QTL 378	3.08	0.05	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	176869060	221869060	Rat
1354624	Cm35	Cardiac mass QTL35	5.7		heart left ventricle mass (VT:0007031)	calculated heart weight (CMO:0000073)	1	177227632	256448636	Rat
1354652	Kidm20	Kidney mass QTL 20	4.3		kidney mass (VT:0002707)	calculated kidney weight (CMO:0000160)	1	177227632	256448636	Rat
1558658	Bw59	Body weight QTL 59	3.5	0.0003	body mass (VT:0001259)	body weight (CMO:0000012)	1	178784622	223784622	Rat
634321	Hc1	Hypercalciuria QTL 1	2.91		urine calcium amount (VT:0002985)	urine calcium excretion rate (CMO:0000763)	1	178810256	240830002	Rat
1578763	Kidm29	Kidney mass QTL 29	3.3	0.0001	kidney mass (VT:0002707)	both kidneys wet weight (CMO:0000085)	1	179567751	260522016	Rat
6903303	Scl34	Serum cholesterol QTL 34	2.5	0.0033	blood cholesterol amount (VT:0000180)	plasma total cholesterol level (CMO:0000585)	1	180359209	218108781	Rat
737977	Bp160	Blood pressure QTL 160		0.001	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	1	181133855	226133855	Rat
724559	Pancm1	Pancreatic morphology QTL 1	7.1		islet of Langerhans morphology trait (VT:0005215)	pancreatic islet damage composite score (CMO:0001156)	1	181759564	214537555	Rat
2293083	Iddm25	Insulin dependent diabetes mellitus QTL 25	4.18		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	1	181829673	224569684	Rat
634312	Bp143	Blood pressure QTL 143	3	0.0002	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	182623426	219932796	Rat
8655655	Arrd2	Age-related retinal degeneration QTL 2	7.79		retinal layer morphology trait (VT:0003727)	percentage of study population developing retinopathy during a period of time (CMO:0002453)	1	183970203	243914901	Rat
8655855	Arrd3	Age-related retinal degeneration QTL 3	3.07		lens clarity trait (VT:0001304)	cataract incidence/prevalence measurement (CMO:0001585)	1	183970203	243914901	Rat
631838	Niddm36	Non-insulin dependent diabetes mellitus QTL 36		0.01	insulin secretion trait (VT:0003564)	calculated pancreatic islet insulin release measurement (CMO:0001217)	1	184550676	229550676	Rat
1300145	Rf7	Renal function QTL 7	2.96		urine creatinine amount (VT:0010540)	urine creatinine level (CMO:0000125)	1	185145134	221264292	Rat
2312564	Glom18	Glomerulus QTL 18	2.4	0.003	kidney glomerulus morphology trait (VT:0005325)	index of glomerular damage (CMO:0001135)	1	185356336	231689108	Rat
1582206	Kidm33	Kidney mass QTL 33	6.9		kidney mass (VT:0002707)	both kidneys wet weight to body weight ratio (CMO:0000340)	1	188377360	224054420	Rat
1358898	Bp255	Blood pressure QTL 255	3.6		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	1	191019702	246062233	Rat
10059590	Kidm44	Kidney mass QTL 44	3.42	0.025	kidney mass (VT:0002707)	both kidneys wet weight to body weight ratio (CMO:0000340)	1	191033875	236033875	Rat
1358191	Ept10	Estrogen-induced pituitary tumorigenesis QTL 10	3.8		pituitary gland mass (VT:0010496)	pituitary gland wet weight (CMO:0000853)	1	192825253	243914732	Rat
8552891	Epfw5	Epididymal fat weight QTL 5	4.4		epididymal fat pad mass (VT:0010421)	epididymal fat pad weight to body weight ratio (CMO:0000658)	1	193113876	238113876	Rat
634338	Hcar4	Hepatocarcinoma resistance QTL 4	4.6		liver integrity trait (VT:0010547)	liver tumorous lesion number to liver area ratio (CMO:0001210)	1	193422268	214537671	Rat
1600388	Niddm67	Non-insulin dependent diabetes mellitus QTL 67	5.84	0.000004	blood glucose amount (VT:0000188)	blood glucose level area under curve (AUC) (CMO:0000350)	1	195804352	257091168	Rat
1600395	Niddm69	Non-insulin dependent diabetes mellitus QTL 69	4.14	0.0002	blood insulin amount (VT:0001560)	plasma insulin level (CMO:0000342)	1	195804352	257091168	Rat
1600396	Niddm68	Non-insulin dependent diabetes mellitus QTL 68	4.97	0.0003	blood glucose amount (VT:0000188)	blood glucose level area under curve (AUC) (CMO:0000350)	1	195804352	257091168	Rat
631658	Cm7	Cardiac mass QTL 7	5.32	0.0001	aorta mass (VT:0002845)	aorta weight (CMO:0000076)	1	196248093	241248093	Rat
1358292	Cm37	Cardiac mass QTL 37	6.2	0.00000081	heart mass (VT:0007028)	heart weight to body weight ratio (CMO:0000074)	1	196248093	241248093	Rat
1600374	Mcs17	Mammary carcinoma susceptibility QTL 17	3		mammary gland integrity trait (VT:0010552)	mammary tumor number (CMO:0000343)	1	197670404	242670404	Rat
1641926	Teswt2	Testicular weight QTL 2	2.82		testis mass (VT:1000644)	both testes wet weight (CMO:0000175)	1	197697768	238755659	Rat
2302375	Bw83	Body weight QTL 83	4.87	0.0002	body mass (VT:0001259)	body weight (CMO:0000012)	1	197697768	242697768	Rat
61376	Bp42	Blood pressure QTL 42	23.4		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	197814409	242814409	Rat
1298084	Thym4	Thymus enlargement QTL 4	10.68		thymus mass (VT:0004954)	thymus weight to body weight ratio (CMO:0000612)	1	197814409	242814409	Rat
1357335	Bw39	Body weight QTL 39	3.3		body mass (VT:0001259)	body weight (CMO:0000012)	1	197814409	242814409	Rat
1331790	Bp201	Blood pressure QTL 201	3.127		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	1	198211513	225126682	Rat
634313	Niddm43	Non-insulin dependent diabetes mellitus QTL 43			blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	1	199050459	259647894	Rat
2292218	Kidm35	Kidney mass QTL 35			kidney mass (VT:0002707)	both kidneys wet weight to body weight ratio (CMO:0000340)	1	199368955	224569684	Rat
2293694	Bss38	Bone structure and strength QTL 38	7.05	0.0001	femur strength trait (VT:0010010)	femur stiffness (CMO:0001674)	1	201554356	246554356	Rat
7394701	Uae46	Urinary albumin excretion QTL 46	3.6	0.0056	urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	1	201554356	246554356	Rat
2300175	Bmd40	Bone mineral density QTL 40	15.4	0.0001	femur mineral mass (VT:0010011)	bone mineral density (CMO:0001226)	1	201554356	246554356	Rat
2293655	Bss36	Bone structure and strength QTL 36	10.66	0.0001	femur strength trait (VT:0010010)	femur ultimate force (CMO:0001675)	1	201554356	246554356	Rat
2293674	Bss39	Bone structure and strength QTL 39	7.1	0.0001	femur strength trait (VT:0010010)	femur total energy absorbed before break (CMO:0001677)	1	201554356	246554356	Rat
10059587	Bw173	Body weight QTL 173	3.23	0.025	body mass (VT:0001259)	body weight (CMO:0000012)	1	202069611	247069611	Rat
1600363	Hc6	Hypercalciuria QTL 6	2.7		urine calcium amount (VT:0002985)	urine calcium excretion rate (CMO:0000763)	1	203995416	244113296	Rat
1600397	Edcs4	Endometrial carcinoma susceptibility QTL 4	2.2		uterus morphology trait (VT:0001120)	percentage of study population developing endometrioid carcinoma during a period of time (CMO:0001759)	1	206081677	251081677	Rat
61403	Niddm4	Non-insulin dependent diabetes mellitus QTL 4			blood glucose amount (VT:0000188)	plasma glucose level (CMO:0000042)	1	206329708	222745518	Rat
1357399	Bw45	Body weight QTL 45	3.05		body mass (VT:0001259)	body mass index (BMI) (CMO:0000105)	1	206329708	251329708	Rat
1357404	Bw42	Body weight QTL 42	4.49	0.0001	body mass (VT:0001259)	body weight (CMO:0000012)	1	206329708	251329708	Rat
1300168	Bp170	Blood pressure QTL 170	2.76		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	1	207702246	228581766	Rat
1358916	Kidm22	Kidney mass QTL 22	3.32		kidney mass (VT:0002707)	both kidneys wet weight to body weight ratio (CMO:0000340)	1	210702053	240947965	Rat
1358890	Bp259	Blood pressure QTL 259	3.06		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	1	210702053	260522016	Rat
2292216	Bw80	Body weight QTL 80	3.23	0.0019	body mass (VT:0001259)	body weight (CMO:0000012)	1	213533809	243914901	Rat
724538	Kidm1	Kidney mass QTL 1	3.2		kidney mass (VT:0002707)	calculated kidney weight (CMO:0000160)	1	213707201	252085212	Rat
734768	Niddm59	Non-insulin dependent diabetes mellitus QTL 59			body mass (VT:0001259)	body weight (CMO:0000012)	1	213843987	258843987	Rat

Markers in Region

RH142098

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	1	213,897,187 - 213,897,402 (+)	MAPPER	mRatBN7.2
Rnor_6.0	1	235,347,702 - 235,347,916	NCBI	Rnor6.0
Rnor_5.0	1	242,665,546 - 242,665,760	UniSTS	Rnor5.0
RGSC_v3.4	1	219,983,015 - 219,983,229	UniSTS	RGSC3.4
Celera	1	211,230,716 - 211,230,930	UniSTS
Cytogenetic Map	1	q43	UniSTS

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

	alimentary part of gastrointestinal system	circulatory system	endocrine system	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	appendage
High
Medium										2	7	11
Low	3	10	51	35	19	35	8	8	54	33	30		8
Below cutoff		22	6	6		6		3	12		4

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001013151	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_008760288	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017589265	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	BC090316	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH473953	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JACYVU010000047	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	OU667097	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Reference Sequences

RefSeq Acc Id:

ENSRNOT00000020201 ⟹ ENSRNOP00000020201

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	1	213,716,020 - 213,897,423 (+)	Ensembl
Rnor_6.0 Ensembl	1	235,166,718 - 235,347,937 (+)	Ensembl

RefSeq Acc Id:

NM_001013151 ⟹ NP_001013169

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	1	213,716,020 - 213,897,425 (+)	NCBI
Rnor_6.0	1	235,166,718 - 235,347,939 (+)	NCBI
Rnor_5.0	1	242,484,562 - 242,665,783 (+)	NCBI
RGSC_v3.4	1	219,906,120 - 219,983,252 (+)	RGD
Celera	1	211,049,903 - 211,230,953 (+)	RGD

Sequence:

show sequence

CGAAGGTCTAAGGATTGAGATTTTCAGAACACTGCAGACAGGGACTAGCTGGTCCTTTATCTGC
AAGCCACGCCACACCTGCTGCTAGCCTACGACACCCTACAGTCGCGGAGAGACCACTCTTGCAG
CGGCACCGACGCCCCAACTTTTGATTCGCGGTCTGTGTTGCCTACCTGGGTGCCCAGCTACAGT
GTCTGGGAGCGCACATCTTCTGGAGACAGCGCCACTCACACCGCCCAACTCGCTCTTCTCTCCC
TCCCAAGCGCCGGGTTGAGTGCCTGATCCGGGACCACACAAGCACTCAGGACTCGCCGGACCTC
GGAACTACCTTCGAGAAAGCGGTTAGCCCAGGAGGTCCGAGCCTCTTGCTCCATACCATAGTCT
GTTCAAGTGTTTCCTCTTCAAATCCAGCGCCTGGCGCGGATAATCCGCACAGCCGGGCTTTAAA
CTCCAGGTCCCTGTCGCTCTGTTGGGGTGGTAAGCCATGGCCGGCTGCTGCTGTCTGTCTGCGG
AGGAGAAAGAGTCGCAGCGCATCAGCGCGGAGATTGAACGGCAACTTCGCCGCGACAAGAAGGA
CGCGCGCCGCGAGCTCAAGCTGTTGTTGCTGGGAACTGGTGAGAGTGGGAAAAGCACCTTTATC
AAGCAGATGAGGATAATCCACGGGTCTGGCTACAGCGATGAAGATAGAAAGGGCTTCACGAAGC
TGGTTTACCAAAACATATTCACGGCCATGCAAGCCATGATCAGAGCAATGGACACCCTGAGGAT
ACAATACACGTGTGAGCAGAATAAGGAAAATGCCCAGATCATCAGAGAAGTGGAAGTAGACAAA
GTCTCTGCGATCTCCAGAGACCAGGTGGCAGCCATCAAGCAGCTGTGGCTGGATCCGGGAATCC
AGGAGTGTTACGACAGGAGGAGGGAGTACCAGCTGTCAGACTCTGCCAAATATTACCTGACGGA
CATTGACCGAATTGCCATGCCCTCTTTCGTGCCAACGCAACAGGACGTACTTCGTGTTCGAGTG
CCTACCACTGGCATCATAGAATATCCATTTGACTTGGAGAACATCATCTTCCGGATGGTGGATG
TTGGTGGCCAGCGATCTGAACGACGGAAATGGATTCACTGCTTTGAGAGCGTCACCTCCATCAT
TTTCTTGGTTGCTCTGAGTGAATATGACCAGGTTCTGGCTGAGTGTGACAATGAGAACCGTATG
GAGGAGAGCAAAGCCCTGTTTAAAACCATCATCACCTACCCCTGGTTTTTGAACTCCTCTGTGA
TTCTGTTCTTAAACAAGAAGGATCTTTTGGAAGAGAAAATCATGTACTCTCATCTAATCAGCTA
CTTCCCAGAGTACACAGGACCAAAGCAAGATGTCAAAGCTGCCAGGGACTTTATCCTCAAGCTG
TATCAAGACCAGAATCCTGACAAAGAGAAAGTCATCTACTCGCACTTCACGTGTGCCACAGACA
CGGAGAACATCCGCTTCGTGTTTGCTGCTGTCAAGGACACGATCCTGCAGCTGAACCTGCGGGA
GTTCAACTTGGTGTAAATGGAGGTCGAGCTGAGCTCTTTCTTCCTGCCCAATCTACAAGTGCTT
CTGACCACCTGGACCAGGACCCAAGAACATTACATAGCCTGCAGCACAGAGATGGACAGTGCAA
TGTGAAAAATACTTTACCAACCCTTTTAAGTGTCTTTAATTCTTGATGGTGTAATTCTTTTCTT
ACCTTTTGGCTCTACGATTAGGTATAATTTTTGAGTGATTTCCTCCCTTTTTTAAACTAGTGCT
CAACAGCTATTAAAAATCACGTAACAGAGGGACTTGTTAATTTACAAATCATGGCTTCAGACCT
CTGAGATTCATTTAGGTGCCTAAAACATCTTCATAGGCTTGATAATTTTAAAATAAATTTTAAG
GAAACATTTCTAACATTTCTTCCCCTTAATGCTGAAGTATGACTCATGTAACATTTTGTTAAAC
CAAAAAGCTTCTTTCTATGCCTTTTTTGGGGTTATTTTTTTATTTAAAAACAGGCTTAAGTAGT
CCAGGCTGGCTTCCAATTCAATGTAATTGAGCATGGCCTTGGTCCTCCTGCCTGAATGTTCCAT
GCTCAGCTAGGACTTTTTTTCTGAGACAGGCCTCATGCATTCCATTCTGGTCTCTCACACACTA
TGTGGTCGAGGAAGACCTTGGACTTCTGATTCTTTTGTCTTCATATACACAACCTATTTAAGGC
AGTTCTCCCATGGTTGCTAATTCCTAACACTAAGAGATCTCAAACAGTGTGATTTCACATTGAC
ATTTACAGGTTAGTAATGGTTGGATGTATGTGTCACATAATAATTTAAGTGATGCATGGGATGG
GACCCAGGGCTTTGTGCATGCTAGGCAAATGTTCTGCCAATGGAGCTATACCCCCAGTCAAAGA
TTTAAAAAGCAGTTCTTTTCATGTCAGCTTTCTAATCCAAATTATTATTATCCAAACATTAATT
TTGCCACAATTTGATAACACCAACTGTGACATATGATAAGTGGACTCTAGATATTGCATTGTGT
GTGTCCTGATGCAACATGGCCGGGTCTTATAGCTTATGGAATGGTTAAAGCATAACTTGTTTAG
CAGATGTTATATAAACCTTGTCAAAGCTCTGGTGGCAACCACAAATGTGCTGTTTGAACTGTGT
ACGCTGTGCCTTTCTGGATACTAAGAATACACTGTTCTACCCTCAAAAAAAAAAAAAAAAAAAA
AAAAAAAGG

hide sequence

RefSeq Acc Id:

XM_008760288 ⟹ XP_008758510

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	1	213,714,993 - 213,900,083 (+)	NCBI
Rnor_6.0	1	235,165,775 - 235,347,986 (+)	NCBI

Sequence:

show sequence

TTATCTGCACCTTAAAATCTGCACAGACAAAATCAGCGAGGGTAATTTGCCTTTCCATTTGAGT
TGTCAAGGGTGCTTTTAGATTTCCCACATCTACTCGCAAGAGTTCCAGGAGCTGTCCGGAAGCA
GCAGTCTGGCTGCAGGGCTGGGCAGGGAACTGGCCAGGTGTGCCGGGAAGGTGCCAACTCTTTC
TACAAAGCAGAAGTCTTTTCCATCATCGAATGCAAAGCAGCCAGCCGGTTTCCACCCTCACCTC
TCCAGTCCCCGGCCCCCTCATCCGGTGCGGGGAGATAGAACAGGCTGGGAGGCGTTAACTAGCC
CTCTGCTCCTTTCCCGGATCTGGAGGCAGCTGCAGTTCCTAACCCAGCCAGCGGGCCCATCTGC
ACTAGCTTCGAGCTGACCCACGGATTGCGCTAAGCCCAAATTGAGTTGTGGCATCCCGGGAAGC
GGAGTGAGCGGGTCTAGAAACCCCAAGTGTGAGACGTGGAGAAAGAAGCTGGCACCAAAGGCTT
GGGGTAGGTCTTCAGGCAACTCCTGTAGACGTCAAGGCTGTAGGTTCGAGACGCCCCGCCTCCT
CCTGTCACTTAGAGCCATCACTCCAGAGTCCTGGAGGAACCTTCCATTCGGCGAAGGTCTAAGG
ATTGAGATTTTCAGAACACTGCAGACAGGGACTAGCTGGTCCTTTATCTGCAAGCCACGCCACA
CCTGCTGCTAGCCTACGACACCCTACAGTCGCGGAGAGACCACTCTTGCAGCGGCACCGACGCC
CCAACTTTTGATTCGCGGTCTGTGTTGCCTACCTGGGTGCCCAGCTACAGTGTCTGGGAGCGCA
CATCTTCTGGAGACAGCGCCACTCACACCGCCCAACTCGCTCTTCTCTCCCTCCCAAGCGCCGG
GTTGAGTGCCTGATCCGGGACCACACAAGCACTCAGGACTCGCCGGACCTCGGAACTACCTTCG
AGAAAGCGGTTAGCCCAGGAGGTCCGAGCCTCTTGCTCCATACCATAGTCTGTTCAAGTGTTTC
CTCTTCAAATCCAGCGCCTGGCGCGGATAATCCGCACAGCCGGGCTTTAAACTCCAGGTCCCTG
TCGCTCTGTTGGGGTGGTAAGCCATGGCCGGCTGCTGCTGTCTGTCTGCGGAGGAGAAAGAGTC
GCAGCGCATCAGCGCGGAGATTGAACGGCAACTTCGCCGCGACAAGAAGGACGCGCGCCGCGAG
CTCAAGCTGTTGTTGCTGGGAACTGGTGAGAGTGGGAAAAGCACCTTTATCAAGCAGATGAGGA
TAATCCACGGGTCTGGCTACAGCGATGAAGATAGAAAGGGCTTCACGAAGCTGGTTTACCAAAA
CATATTCACGGCCATGCAAGCCATGATCAGAGCAATGGACACCCTGAGGATACAATACACGTGT
GAGCAGAATAAGGAAAATGCCCAGATCATCAGAGAAGTGGAAGTAGACAAAGTCTCTGCGATCT
CCAGAGACCAGGTGGCAGCCATCAAGCAGCTGTGGCTGGATCCGGGAATCCAGGAGTGTTACGA
CAGGAGGAGGGAGTACCAGCTGTCAGACTCTGCCAAATATTACCTGACGGACATTGACCGAATT
GCCATGCCCTCTTTCGTGCCAACGCAACAGGACGTACTTCGTGTTCGAGTGCCTACCACTGGCA
TCATAGAATATCCATTTGACTTGGAGAACATCATCTTCCGGATGGTGGATGTTGGTGGCCAGCG
ATCTGAACGACGGAAATGGATTCACTGCTTTGAGAGCGTCACCTCCATCATTTTCTTGGTTGCT
CTGAGTGAATATGACCAGGTTCTGGCTGAGTGTGACAATGAGAACCGTATGGAGGAGAGCAAAG
CCCTGTTTAAAACCATCATCACCTACCCCTGGTTTTTGAACTCCTCTGTGATTCTGTTCTTAAA
CAAGAAGGATCTTTTGGAAGAGAAAATCATGTACTCTCATCTAATCAGCTACTTCCCAGAGTAC
ACAGGACCAAAGCAAGATGTCAAAGCTGCCAGGGACTTTATCCTCAAGCTGTATCAAGACCAGA
ATCCTGACAAAGAGAAAGTCATCTACTCGCACTTCACGTGTGCCACAGACACGGAGAACATCCG
CTTCGTGTTTGCTGCTGTCAAGGACACGATCCTGCAGCTGAACCTGCGGGAGTTCAACTTGGTG
TAAATGGAGGTCGAGCTGAGCTCTTTCTTCCTGCCCAATCTACAAGTGCTTCTGACCACCTGGA
CCAGGACCCAAGAACATTACATAGCCTGCAGCACAGAGATGGACAGTGCAATGTGAAAAATACT
TTACCAACCCTTTTAAGTGTCTTTAATTCTTGATGGTGTAATTCTTTTCTTACCTTTTGGCTCT
ACGATTAGGTATAATTTTTGAGTGATTTCCTCCCTTTTTTAAACTAGTGCTCAACAGCTATTAA
AAATCACGTAACAGAGGGACTTGTTAATTTACAAATCATGGCTTCAGACCTCTGAGATTCATTT
AGGTGCCTAAAACATCTTCATAGGCTTGATAATTTTAAAATAAATTTTAAGGAAACATTTCTAA
CATTTCTTCCCCTTAATGCTGAAGTATGACTCATGTAACATTTTGTTAAACCAAAAAGCTTCTT
TCTATGCCTTTTTTGGGGTTATTTTTTTATTTAAAAACAGGCTTAAGTAGTCCAGGCTGGCTTC
CAATTCAATGTAATTGAGCATGGCCTTGGTCCTCCTGCCTGAATGTTCCATGCTCAGCTAGGAC
TTTTTTTCTGAGACAGGCCTCATGCATTCCATTCTGGTCTCTCACACACTATGTGGTCGAGGAA
GACCTTGGACTTCTGATTCTTTTGTCTTCATATACACAACCTATTTAAGGCAGTTCTCCCATGG
TTGCTAATTCCTAACACTAAGAGATCTCAAACAGTGTGATTTCACATTGACATTTACAGGTTAG
TAATGGTTGGATGTATGTGTCACATAATAATTTAAGTGATGCATGGGATGGGACCCAGGGCTTT
GTGCATGCTAGGCAAATGTTCTGCCAATGGAGCTATACCCCCAGTCAAAGATTTAAAAAGCAGT
TCTTTTCATGTCAGCTTTCTAATCCAAATTATTATTATCCAAACATTAATTTTGCCACAATTTG
ATAACACCAACTGTGACATATGATAAGTGGACTCTAGATATTGCATTGTGTGTGTCCTGATGCA
ACATGGCCGGGTCTTATAGCTTATGGAATGGTTAAAGCATAACTTGTTTAGCAGATGTTATATA
AACCTTGTCAAAGCTCTGGTGGCAACCACAAATGTGCTGTTTGAACTGTGTACGCTGTGCCTTT
CTGGATACTAAGAATACACTGTTCTACCCTCAACACCGATGATGATGTGCTTCTTAGAGCTCAC
GGCTGATGGTTCTGTT

hide sequence

Protein Sequences


Protein RefSeqs	NP_001013169	(Get FASTA)	NCBI Sequence Viewer
	XP_008758510	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAH90316	(Get FASTA)	NCBI Sequence Viewer
	CAG9553615	(Get FASTA)	NCBI Sequence Viewer
	EDM12964	(Get FASTA)	NCBI Sequence Viewer
	EDM12965	(Get FASTA)	NCBI Sequence Viewer

Reference Sequences

RefSeq Acc Id:

NP_001013169 ⟸ NM_001013151

- UniProtKB:

Q5EAP4 (UniProtKB/TrEMBL), F1LRE6 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MAGCCCLSAEEKESQRISAEIERQLRRDKKDARRELKLLLLGTGESGKSTFIKQMRIIHGSGYS
DEDRKGFTKLVYQNIFTAMQAMIRAMDTLRIQYTCEQNKENAQIIREVEVDKVSAISRDQVAAI
KQLWLDPGIQECYDRRREYQLSDSAKYYLTDIDRIAMPSFVPTQQDVLRVRVPTTGIIEYPFDL
ENIIFRMVDVGGQRSERRKWIHCFESVTSIIFLVALSEYDQVLAECDNENRMEESKALFKTIIT
YPWFLNSSVILFLNKKDLLEEKIMYSHLISYFPEYTGPKQDVKAARDFILKLYQDQNPDKEKVI
YSHFTCATDTENIRFVFAAVKDTILQLNLREFNLV

hide sequence

RefSeq Acc Id:	XP_008758510 ⟸ XM_008760288
- Peptide Label:	isoform X1
- UniProtKB:	Q5EAP4 (UniProtKB/TrEMBL), F1LRE6 (UniProtKB/TrEMBL)
- Sequence:	show sequence MAGCCCLSAEEKESQRISAEIERQLRRDKKDARRELKLLLLGTGESGKSTFIKQMRIIHGSGYS DEDRKGFTKLVYQNIFTAMQAMIRAMDTLRIQYTCEQNKENAQIIREVEVDKVSAISRDQVAAI KQLWLDPGIQECYDRRREYQLSDSAKYYLTDIDRIAMPSFVPTQQDVLRVRVPTTGIIEYPFDL ENIIFRMVDVGGQRSERRKWIHCFESVTSIIFLVALSEYDQVLAECDNENRMEESKALFKTIIT YPWFLNSSVILFLNKKDLLEEKIMYSHLISYFPEYTGPKQDVKAARDFILKLYQDQNPDKEKVI YSHFTCATDTENIRFVFAAVKDTILQLNLREFNLV hide sequence

RefSeq Acc Id:

ENSRNOP00000020201 ⟸ ENSRNOT00000020201

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-Q5EAP4-F1-model_v2	AlphaFold	Q5EAP4	1-355	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13690808

Promoter ID:

EPDNEW_R1333

Type:

single initiation site

Name:

Gna14_1

Description:

G protein subunit alpha 14

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	1	235,166,712 - 235,166,772	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1308122	AgrOrtholog
BioCyc Gene	G2FUF-56219	BioCyc
Ensembl Genes	ENSRNOG00000014840	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein	ENSRNOP00000020201	ENTREZGENE
	ENSRNOP00000020201.7	UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000020201	ENTREZGENE
	ENSRNOT00000020201.8	UniProtKB/TrEMBL
Gene3D-CATH	1.10.400.10	UniProtKB/TrEMBL
	3.40.50.300	UniProtKB/TrEMBL
IMAGE_CLONE	IMAGE:7305112	IMAGE-MGC_LOAD
InterPro	Gprotein_alpha_Q	UniProtKB/TrEMBL
	Gprotein_alpha_su	UniProtKB/TrEMBL
	GproteinA_insert	UniProtKB/TrEMBL
	P-loop_NTPase	UniProtKB/TrEMBL
KEGG Report	rno:309242	UniProtKB/TrEMBL
MGC_CLONE	MGC:105546	IMAGE-MGC_LOAD
NCBI Gene	309242	ENTREZGENE
PANTHER	Gprotein_alph_bd	UniProtKB/TrEMBL
	GUANINE NUCLEOTIDE-BINDING PROTEIN SUBUNIT ALPHA-14	UniProtKB/TrEMBL
Pfam	G-alpha	UniProtKB/TrEMBL
PhenoGen	Gna14	PhenoGen
PRINTS	GPROTEINA	UniProtKB/TrEMBL
	GPROTEINAQ	UniProtKB/TrEMBL
PROSITE	G_ALPHA	UniProtKB/TrEMBL
SMART	G_alpha	UniProtKB/TrEMBL
Superfamily-SCOP	SSF52540	UniProtKB/TrEMBL
	Transducn_insert	UniProtKB/TrEMBL
UniProt	A0A8J8XRQ3_RAT	UniProtKB/TrEMBL
	F1LRE6	ENTREZGENE
	Q5EAP4	ENTREZGENE, UniProtKB/TrEMBL
UniProt Secondary	F1LRE6	UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2016-05-11	Gna14	G protein subunit alpha 14	Gna14	guanine nucleotide binding protein, alpha 14	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2006-03-30	Gna14	guanine nucleotide binding protein, alpha 14	Tieg3	TGFB inducible early growth response 3	Symbol and Name updated	1299863	APPROVED
2005-12-06	Tieg3	TGFB inducible early growth response 3	Tieg3_predicted	TGFB inducible early growth response 3 (predicted)	Symbol and Name updated	1559027	APPROVED
2005-01-12	Tieg3_predicted	TGFB inducible early growth response 3 (predicted)			Symbol and Name status set to approved	70820	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

RGD Manual Annotations

Imported Annotations - KEGG (archival)

Imported Annotations - PID (archival)

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Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

RGD Manual Annotations

Imported Annotations - KEGG (archival)

Imported Annotations - PID (archival)