(3,4-dihydroxyphenyl)acetic acid multiple interactions EXP 6480464 3, 4-Dihydroxyphenylacetic Acid inhibits the reaction [SLC22A8 protein results in increased uptake of estrone sulfate] CTD PMID:10224140 (R)-carnitine increases transport ISO RGD:732953 6480464 SLC22A8 protein results in increased transport of Carnitine CTD PMID:15100168 1,1-dichloroethene decreases expression ISO RGD:732953 6480464 vinylidene chloride results in decreased expression of SLC22A8 mRNA CTD PMID:26682919 1-naphthyl isothiocyanate decreases expression EXP 6480464 1-Naphthylisothiocyanate results in decreased expression of SLC22A8 mRNA CTD PMID:25380136 , PMID:30723492 17beta-estradiol 17-glucosiduronic acid multiple interactions EXP 6480464 estradiol-17 beta-glucuronide inhibits the reaction [SLC22A8 protein results in increased uptake of Cimetidine] CTD PMID:15319347 17beta-estradiol 17-glucosiduronic acid affects transport ISO RGD:732952 6480464 SLC22A8 protein affects the transport of estradiol-17 beta-glucuronide CTD PMID:11306713 2,2',4,4',5,5'-hexachlorobiphenyl multiple interactions ISO RGD:732953 6480464 [2 more ... CTD PMID:25510870 2,2',5,5'-tetrachlorobiphenyl multiple interactions ISO RGD:732953 6480464 [2 more ... CTD PMID:25510870 2,2,3,3,4,4,5,5,6,6,7,7,8,8,9,9-hexadecafluorononanoic acid multiple interactions EXP 6480464 hexadecafluoro-nonanoic acid inhibits the reaction [SLC22A8 protein results in increased import of estrone sulfate] CTD PMID:19915082 2,2,3,3,4,4,5,5,6,6,7,7,8,8,9,9-hexadecafluorononanoic acid increases import EXP 6480464 SLC22A8 protein results in increased import of hexadecafluoro-nonanoic acid CTD PMID:19915082 2,3,7,8-tetrachlorodibenzodioxine decreases expression EXP 6480464 Tetrachlorodibenzodioxin results in decreased expression of SLC22A8 mRNA CTD PMID:21215274 2,3,7,8-tetrachlorodibenzodioxine decreases expression ISO RGD:732953 6480464 Tetrachlorodibenzodioxin results in decreased expression of SLC22A8 mRNA CTD PMID:33956508 2,3,7,8-Tetrachlorodibenzofuran decreases expression EXP 6480464 2 more ... CTD PMID:32109520 2-Amino-9H-pyrido[2,3-b]indole multiple interactions ISO RGD:732952 6480464 2-amino-1-methyl-6-phenylimidazo(4 more ... CTD PMID:28629854 2-Amino-9H-pyrido[2,3-b]indole decreases activity ISO RGD:732952 6480464 2-amino-9H-pyrido(2, 3-b)indole results in decreased activity of SLC22A8 protein CTD PMID:28629854 3',5'-cyclic AMP affects transport ISO RGD:732952 6480464 SLC22A8 protein affects the transport of Cyclic AMP CTD PMID:11306713 3,3',5,5'-tetrabromobisphenol A decreases activity ISO RGD:732952 6480464 tetrabromobisphenol A results in decreased activity of SLC22A8 protein CTD PMID:27989701 3,3',5,5'-tetrabromobisphenol A multiple interactions ISO RGD:732952 6480464 tetrabromobisphenol A inhibits the reaction [SLC22A8 protein results in increased uptake of estrone sulfate] CTD PMID:27989701 3,4-dihydroxymandelic acid multiple interactions EXP 6480464 3, 4-dihydroxymandelic acid inhibits the reaction [SLC22A8 protein results in increased uptake of estrone sulfate] CTD PMID:10224140 3,7-dihydropurine-6-thione increases transport ISO RGD:732953 6480464 SLC22A8 protein results in increased transport of Mercaptopurine CTD PMID:15100168 3-Amino-1-methyl-5H-pyrido[4,3-b]indole decreases activity ISO RGD:732952 6480464 3-amino-1-methyl-5H-pyrido(4, 3-b)indole results in decreased activity of SLC22A8 protein CTD PMID:28629854 3-Amino-1-methyl-5H-pyrido[4,3-b]indole multiple interactions ISO RGD:732952 6480464 3-amino-1-methyl-5H-pyrido(4, 3-b)indole inhibits the reaction [SLC22A8 protein results in increased import of 6-carboxyfluorescein] CTD PMID:28629854 3-chloropropane-1,2-diol increases expression EXP 6480464 alpha-Chlorohydrin results in increased expression of SLC22A8 mRNA CTD PMID:28522335 4,4'-diaminodiphenylmethane decreases expression EXP 6480464 4, 4'-diaminodiphenylmethane results in decreased expression of SLC22A8 mRNA CTD PMID:25380136 4,4'-sulfonyldiphenol decreases activity ISO RGD:732952 6480464 bis(4-hydroxyphenyl)sulfone results in decreased activity of SLC22A8 protein CTD PMID:27989701 4,4'-sulfonyldiphenol multiple interactions ISO RGD:732952 6480464 bis(4-hydroxyphenyl)sulfone inhibits the reaction [SLC22A8 protein results in increased uptake of estrone sulfate] CTD PMID:27989701 5-azaorotic acid multiple interactions EXP 6480464 [Oxonic Acid co-treated with Uric Acid] results in decreased expression of SLC22A8 protein CTD PMID:19605544 5-carboxyfluorescein increases transport ISO RGD:732952 6480464 SLC22A8 protein results in increased transport of 4-carboxyfluorescein CTD PMID:21244849 5-carboxyfluorescein multiple interactions ISO RGD:732952 6480464 quercetin 3'-sulfate inhibits the reaction [SLC22A8 protein results in increased transport of 4-carboxyfluorescein] more ... CTD PMID:21244849 5-fluorouracil increases transport ISO RGD:732953 6480464 SLC22A8 protein results in increased transport of Fluorouracil CTD PMID:15100168 5-formyltetrahydrofolic acid multiple interactions EXP 6480464 Leucovorin inhibits the reaction [Methotrexate results in decreased expression of SLC22A8 protein] CTD PMID:16925582 5-formyltetrahydrofolic acid increases uptake ISO RGD:732952 6480464 SLC22A8 protein results in increased uptake of Leucovorin CTD PMID:16098483 5-methoxy-2-\{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl\}-1H-benzimidazole multiple interactions ISO RGD:732952 6480464 [Omeprazole results in decreased activity of SLC22A8 protein] which results in decreased uptake of Indican CTD PMID:36243147 5-methoxyindole-3-acetic acid multiple interactions EXP 6480464 5-methoxyindoleacetic acid inhibits the reaction [SLC22A8 protein results in increased uptake of estrone sulfate] CTD PMID:10224140 5-Methoxytryptophol multiple interactions EXP 6480464 methoxytryptophol inhibits the reaction [SLC22A8 protein results in increased uptake of estrone sulfate] CTD PMID:10224140 6-carboxyfluorescein increases import ISO RGD:732952 6480464 SLC22A8 protein results in increased import of 6-carboxyfluorescein CTD PMID:28629854 6-carboxyfluorescein multiple interactions ISO RGD:732952 6480464 2-amino-1-methyl-6-phenylimidazo(4 more ... CTD PMID:28629854 6-propyl-2-thiouracil decreases expression EXP 6480464 Propylthiouracil results in decreased expression of SLC22A8 mRNA CTD PMID:25825206 7,9-dihydro-1H-purine-2,6,8(3H)-trione affects transport ISO RGD:732952 6480464 SLC22A8 protein affects the transport of Uric Acid CTD PMID:11306713 7,9-dihydro-1H-purine-2,6,8(3H)-trione multiple interactions EXP 6480464 [Oxonic Acid co-treated with Uric Acid] results in decreased expression of SLC22A8 protein CTD PMID:19605544 acetamide decreases expression EXP 6480464 acetamide results in decreased expression of SLC22A8 mRNA CTD PMID:31881176 acetamiprid decreases activity ISO RGD:732952 6480464 acetamiprid results in decreased activity of SLC22A8 protein CTD PMID:31364238 acetylsalicylic acid increases expression ISO RGD:732952 6480464 Aspirin results in increased expression of SLC22A8 mRNA CTD PMID:11906190 adefovir increases response to substance ISO RGD:732952 6480464 SLC22A8 protein results in increased susceptibility to adefovir CTD PMID:25448811 adefovir decreases expression EXP 6480464 adefovir results in decreased expression of SLC22A8 protein CTD PMID:35114312 adefovir multiple interactions EXP 6480464 [adefovir co-treated with Probenecid co-treated with Cromolyn Sodium] results in increased expression of SLC22A8 protein more ... CTD PMID:35114312 aflatoxin B1 affects methylation ISO RGD:732952 6480464 Aflatoxin B1 affects the methylation of SLC22A8 intron CTD PMID:30157460 Aflatoxin B2 alpha increases methylation ISO RGD:732952 6480464 aflatoxin B2 results in increased methylation of SLC22A8 intron CTD PMID:30157460 agomelatine multiple interactions EXP 6480464 agomelatine inhibits the reaction [Dietary Fats results in decreased expression of SLC22A8 protein] CTD PMID:34081941 allopurinol increases transport ISO RGD:732953 6480464 SLC22A8 protein results in increased transport of Allopurinol CTD PMID:15100168 ammonium chloride affects expression EXP 6480464 Ammonium Chloride affects the expression of SLC22A8 mRNA CTD PMID:16483693 angelicin increases expression ISO RGD:732953 6480464 angelicin results in increased expression of SLC22A8 protein CTD PMID:22173200 angelicin decreases expression ISO RGD:732953 6480464 angelicin results in decreased expression of SLC22A8 mRNA CTD PMID:22173200 aristolochic acid A multiple interactions ISO RGD:732952 6480464 [wedelolactone results in decreased activity of SLC22A8 protein] which results in increased susceptibility to and results in increased activity of aristolochic acid I more ... CTD PMID:19643159 , PMID:32159797 aristolochic acids increases uptake ISO RGD:732952 6480464 SLC22A8 results in increased uptake of Aristolochic Acids CTD PMID:19643159 aristolochic acids multiple interactions ISO RGD:732952 6480464 [SLC22A8 results in increased uptake of Aristolochic Acids] which results in increased chemical synthesis of 7-(deoxyadenosin-N(6)-yl)aristolactam I more ... CTD PMID:19643159 aristolochic acids decreases expression EXP 6480464 Aristolochic Acids results in decreased expression of SLC22A8 mRNA, Aristolochic Acids results in decreased expression of SLC22A8 protein CTD PMID:21167265 atrazine increases expression ISO RGD:732952 6480464 Atrazine results in increased expression of SLC22A8 mRNA CTD PMID:22378314 aurantio-obtusin decreases activity ISO RGD:732952 6480464 aurantio-obtusin results in decreased activity of SLC22A8 protein CTD PMID:29045746 bendroflumethiazide decreases activity ISO RGD:732953 6480464 Bendroflumethiazide results in decreased activity of SLC22A8 protein CTD PMID:18216144 bendroflumethiazide increases secretion ISO RGD:732953 6480464 SLC22A8 protein results in increased secretion of Bendroflumethiazide CTD PMID:18216144 benzo[a]pyrene increases methylation ISO RGD:732952 6480464 Benzo(a)pyrene results in increased methylation of SLC22A8 3' UTR CTD PMID:27901495 benzo[a]pyrene decreases activity ISO RGD:732952 6480464 Benzo(a)pyrene results in decreased activity of SLC22A8 protein CTD PMID:31830554 benzo[a]pyrene decreases methylation ISO RGD:732952 6480464 Benzo(a)pyrene results in decreased methylation of SLC22A8 5' UTR CTD PMID:27901495 benzo[a]pyrene affects methylation ISO RGD:732952 6480464 Benzo(a)pyrene affects the methylation of SLC22A8 exon, Benzo(a)pyrene affects the methylation of SLC22A8 promoter CTD PMID:27901495 benzylpenicillin multiple interactions EXP 6480464 Penicillin G inhibits the reaction [SLC22A8 protein results in increased uptake of Cimetidine] more ... CTD PMID:10224140 more ... benzylpenicillin increases uptake EXP 6480464 SLC22A8 protein results in increased uptake of Penicillin G CTD PMID:35019195 benzylpenicillin multiple interactions ISO RGD:732952 6480464 resveratrol inhibits the reaction [SLC22A8 protein results in increased uptake of Penicillin G] CTD PMID:27377006 benzylpenicillin increases uptake ISO RGD:732952 6480464 SLC22A8 protein results in increased uptake of Penicillin G CTD PMID:17255469 , PMID:27377006 bisphenol A decreases expression EXP 6480464 bisphenol A results in decreased expression of SLC22A8 mRNA CTD PMID:25181051 more ... bisphenol A decreases activity ISO RGD:732952 6480464 bisphenol A results in decreased activity of SLC22A8 protein CTD PMID:27989701 bisphenol A multiple interactions ISO RGD:732952 6480464 bisphenol A inhibits the reaction [SLC22A8 protein results in increased uptake of estrone sulfate] CTD PMID:27989701 bisphenol F multiple interactions ISO RGD:732952 6480464 bisphenol F inhibits the reaction [SLC22A8 protein results in increased uptake of estrone sulfate] CTD PMID:27989701 bisphenol F increases expression ISO RGD:732953 6480464 bisphenol F results in increased expression of SLC22A8 mRNA CTD PMID:30951980 bisphenol F decreases activity ISO RGD:732952 6480464 bisphenol F results in decreased activity of SLC22A8 protein CTD PMID:27989701 bromosulfophthalein multiple interactions EXP 6480464 Sulfobromophthalein inhibits the reaction [SLC22A8 protein results in increased uptake of estrone sulfate] CTD PMID:10224140 bumetanide multiple interactions EXP 6480464 Bumetanide inhibits the reaction [SLC22A8 protein results in increased uptake of estrone sulfate] CTD PMID:10224140 bumetanide multiple interactions ISO RGD:732952 6480464 Bumetanide inhibits the reaction [SLC22A8 protein affects the transport of estrone sulfate] CTD PMID:11306713 cadmium dichloride decreases expression EXP 6480464 Cadmium Chloride results in decreased expression of SLC22A8 mRNA, Cadmium Chloride results in decreased expression of SLC22A8 protein CTD PMID:25588984 cadmium dichloride multiple interactions ISO RGD:732952 6480464 Cadmium Chloride promotes the reaction [SLC22A8 protein results in increased import of 6-carboxyfluorescein] CTD PMID:28629854 cadmium dichloride increases activity ISO RGD:732952 6480464 Cadmium Chloride results in increased activity of SLC22A8 protein CTD PMID:28629854 cefaclor increases uptake ISO RGD:732952 6480464 SLC22A8 protein results in increased uptake of Cefaclor CTD PMID:16098483 cefaclor multiple interactions ISO RGD:732952 6480464 Cefaclor inhibits the reaction [SLC22A8 protein results in increased uptake of estrone sulfate] CTD PMID:16098483 cefaloridine increases uptake ISO RGD:732952 6480464 SLC22A8 protein results in increased uptake of Cephaloridine CTD PMID:16098483 cefaloridine multiple interactions ISO RGD:732952 6480464 Cephaloridine inhibits the reaction [SLC22A8 protein results in increased uptake of estrone sulfate] CTD PMID:16098483 cefazolin increases uptake ISO RGD:732952 6480464 SLC22A8 protein results in increased uptake of Cefazolin CTD PMID:16098483 cefdinir multiple interactions ISO RGD:732952 6480464 cefdinir inhibits the reaction [SLC22A8 protein results in increased uptake of estrone sulfate] CTD PMID:16098483 cefdinir increases uptake ISO RGD:732952 6480464 SLC22A8 protein results in increased uptake of cefdinir CTD PMID:16098483 cefoselis sulfate increases uptake ISO RGD:732952 6480464 SLC22A8 protein results in increased uptake of cefoselis CTD PMID:16098483 cefoselis sulfate multiple interactions ISO RGD:732952 6480464 cefoselis inhibits the reaction [SLC22A8 protein results in increased uptake of estrone sulfate] CTD PMID:16098483 cefotiam increases uptake ISO RGD:732952 6480464 SLC22A8 protein results in increased uptake of Cefotiam CTD PMID:16098483 cefotiam multiple interactions ISO RGD:732952 6480464 Cefotiam inhibits the reaction [SLC22A8 protein results in increased uptake of estrone sulfate] CTD PMID:16098483 ceftibuten increases uptake ISO RGD:732952 6480464 SLC22A8 protein results in increased uptake of ceftibuten CTD PMID:16098483 ceftibuten multiple interactions ISO RGD:732952 6480464 ceftibuten inhibits the reaction [SLC22A8 protein results in increased uptake of estrone sulfate] CTD PMID:16098483 ceftizoxime increases uptake ISO RGD:732952 6480464 SLC22A8 protein results in increased uptake of Ceftizoxime CTD PMID:16098483 ceftizoxime multiple interactions ISO RGD:732952 6480464 Ceftizoxime inhibits the reaction [SLC22A8 protein results in increased uptake of estrone sulfate] CTD PMID:16098483 CGP 52608 multiple interactions ISO RGD:732952 6480464 CGP 52608 promotes the reaction [RORA protein binds to SLC22A8 gene] CTD PMID:28238834 cholate multiple interactions ISO RGD:732952 6480464 Cholates inhibits the reaction [SLC22A8 protein affects the transport of estrone sulfate] CTD PMID:11306713 chrysophanol decreases activity ISO RGD:732952 6480464 chrysophanic acid results in decreased activity of SLC22A8 protein CTD PMID:29045746 cidofovir anhydrous increases response to substance ISO RGD:732952 6480464 SLC22A8 protein results in increased susceptibility to Cidofovir CTD PMID:25448811 cimetidine multiple interactions ISO RGD:732952 6480464 Cimetidine inhibits the reaction [SLC22A8 protein affects the transport of estrone sulfate], Probenecid inhibits the reaction [SLC22A8 protein affects the transport of Cimetidine] CTD PMID:15496291 , PMID:16006492 cimetidine increases uptake EXP 6480464 SLC22A8 protein results in increased uptake of Cimetidine CTD PMID:10224140 more ... cimetidine affects transport ISO RGD:732952 6480464 SLC22A8 protein affects the transport of Cimetidine CTD PMID:11306713 cimetidine increases uptake ISO RGD:732952 6480464 SLC22A8 protein results in increased uptake of Cimetidine CTD PMID:16006492 , PMID:16098483 cimetidine multiple interactions ISO RGD:732953 6480464 Cimetidine inhibits the reaction [SLC22A8 protein results in increased uptake of p-Aminohippuric Acid] CTD PMID:15100168 cimetidine multiple interactions EXP 6480464 estradiol-17 beta-glucuronide inhibits the reaction [SLC22A8 protein results in increased uptake of Cimetidine] more ... CTD PMID:15319347 , PMID:16006492 cisplatin multiple interactions EXP 6480464 JBP 485 inhibits the reaction [Cisplatin results in decreased expression of SLC22A8 mRNA] CTD PMID:22992436 cisplatin decreases expression EXP 6480464 Cisplatin results in decreased expression of SLC22A8 mRNA, Cisplatin results in decreased expression of SLC22A8 protein CTD PMID:22992436 clothianidin decreases activity ISO RGD:732952 6480464 clothianidin results in decreased activity of SLC22A8 protein CTD PMID:31364238 corticosterone increases expression EXP 6480464 Corticosterone results in increased expression of SLC22A8 protein CTD PMID:32733244 corticosterone multiple interactions EXP 6480464 O-1602 compound inhibits the reaction [Corticosterone results in increased expression of SLC22A8 protein] CTD PMID:32733244 Cuprizon increases expression EXP 6480464 Cuprizone results in increased expression of SLC22A8 mRNA CTD PMID:26577399 cyazofamid multiple interactions ISO RGD:732952 6480464 cyazofamid inhibits the reaction [SLC22A8 protein results in increased uptake of estrone sulfate] CTD PMID:32003934 D-gluconic acid multiple interactions EXP 6480464 [gluconic acid co-treated with Deoxycholic Acid] results in increased expression of SLC22A8 mRNA CTD PMID:16556975 daidzein increases uptake ISO RGD:732952 6480464 SLC22A8 protein results in increased uptake of daidzein analog CTD PMID:21244849 dehydroepiandrosterone multiple interactions ISO RGD:732952 6480464 Dehydroepiandrosterone inhibits the reaction [SLC22A8 protein affects the transport of estrone sulfate] CTD PMID:11306713 dehydroepiandrosterone sulfate affects transport ISO RGD:732952 6480464 SLC22A8 protein affects the transport of Dehydroepiandrosterone Sulfate CTD PMID:11306713 dehydroepiandrosterone sulfate increases uptake ISO RGD:732952 6480464 SLC22A8 protein results in increased uptake of Dehydroepiandrosterone Sulfate CTD PMID:16098483 , PMID:17255469 deoxycholic acid multiple interactions EXP 6480464 [gluconic acid co-treated with Deoxycholic Acid] results in increased expression of SLC22A8 mRNA CTD PMID:16556975 dexamethasone decreases expression EXP 6480464 Dexamethasone results in decreased expression of SLC22A8 mRNA CTD PMID:19922765 dexamethasone multiple interactions EXP 6480464 Dexamethasone inhibits the reaction [Freund's Adjuvant results in decreased expression of SLC22A8 mRNA] CTD PMID:21149847 dextran sulfate multiple interactions ISO RGD:732953 6480464 [titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of SLC22A8 mRNA CTD PMID:29950665 diazinon increases methylation ISO RGD:732952 6480464 Diazinon results in increased methylation of SLC22A8 gene CTD PMID:22964155 diclofenac multiple interactions ISO RGD:732952 6480464 Diclofenac inhibits the reaction [SLC22A8 protein affects the transport of estrone sulfate] CTD PMID:11306713 disodium cromoglycate multiple interactions EXP 6480464 [adefovir co-treated with Probenecid co-treated with Cromolyn Sodium] results in increased expression of SLC22A8 protein more ... CTD PMID:35114312 , PMID:36464070 emodin decreases activity ISO RGD:732952 6480464 Emodin results in decreased activity of SLC22A8 protein CTD PMID:29045746 enalapril multiple interactions ISO RGD:732953 6480464 Enalapril inhibits the reaction [SLC22A8 protein results in increased uptake of p-Aminohippuric Acid] CTD PMID:15100168 enalaprilat dihydrate multiple interactions ISO RGD:732952 6480464 verlukast inhibits the reaction [SLC22A8 protein results in increased uptake of Enalaprilat] CTD PMID:33007874 enalaprilat dihydrate increases uptake ISO RGD:732952 6480464 SLC22A8 protein results in increased uptake of Enalaprilat CTD PMID:33007874 endosulfan decreases expression EXP 6480464 Endosulfan results in decreased expression of SLC22A8 mRNA CTD PMID:29391264 estrone 3-sulfate multiple interactions ISO RGD:732952 6480464 5 more ... CTD PMID:11306713 more ... estrone 3-sulfate increases import ISO RGD:732952 6480464 SLC22A8 protein results in increased import of estrone sulfate CTD PMID:28629854 estrone 3-sulfate affects transport ISO RGD:732952 6480464 SLC22A8 protein affects the transport of estrone sulfate CTD PMID:11306713 , PMID:15496291 estrone 3-sulfate increases uptake EXP 6480464 SLC22A8 protein results in increased uptake of estrone sulfate CTD PMID:10224140 , PMID:16857889 estrone 3-sulfate affects transport EXP 6480464 SLC22A8 protein affects the transport of estrone sulfate CTD PMID:16079298 estrone 3-sulfate increases uptake ISO RGD:732952 6480464 SLC22A8 protein results in increased uptake of estrone sulfate, SLC22A8 results in increased uptake of estrone sulfate CTD PMID:16098483 more ... estrone 3-sulfate increases import EXP 6480464 SLC22A8 protein results in increased import of estrone sulfate CTD PMID:19915082 estrone 3-sulfate multiple interactions EXP 6480464 3 more ... CTD PMID:10224140 more ... estrone 3-sulfate increases uptake ISO RGD:732953 6480464 SLC22A8 protein results in increased uptake of estrone sulfate CTD PMID:15100168 famotidine multiple interactions ISO RGD:732952 6480464 estrone sulfate inhibits the reaction [SLC22A8 protein results in increased uptake of Famotidine] more ... CTD PMID:15496291 , PMID:16006492 famotidine increases uptake EXP 6480464 SLC22A8 protein results in increased uptake of Famotidine CTD PMID:15319347 , PMID:16006492 famotidine multiple interactions EXP 6480464 Famotidine inhibits the reaction [SLC22A8 protein results in increased uptake of Cimetidine] more ... CTD PMID:15319347 , PMID:16006492 famotidine multiple interactions ISO RGD:732953 6480464 Famotidine inhibits the reaction [SLC22A8 protein results in increased uptake of p-Aminohippuric Acid] CTD PMID:15100168 famotidine increases uptake ISO RGD:732952 6480464 SLC22A8 protein results in increased uptake of Famotidine CTD PMID:15496291 , PMID:16006492 folic acid decreases expression EXP 6480464 Folic Acid results in decreased expression of SLC22A8 mRNA, Folic Acid results in decreased expression of SLC22A8 protein CTD PMID:19552531 folic acid decreases expression ISO RGD:732952 6480464 Folic Acid results in decreased expression of SLC22A8 mRNA CTD PMID:21867686 furan increases methylation EXP 6480464 furan results in increased methylation of SLC22A8 gene CTD PMID:22079235 furosemide decreases activity ISO RGD:732953 6480464 Furosemide results in decreased activity of SLC22A8 protein CTD PMID:18216144 furosemide multiple interactions ISO RGD:732952 6480464 Furosemide inhibits the reaction [SLC22A8 protein affects the transport of estrone sulfate] CTD PMID:11306713 furosemide multiple interactions EXP 6480464 Furosemide inhibits the reaction [SLC22A8 protein results in increased uptake of estrone sulfate] CTD PMID:10224140 furosemide increases secretion ISO RGD:732953 6480464 SLC22A8 protein results in increased secretion of Furosemide CTD PMID:18216144 gentamycin multiple interactions EXP 6480464 JBP 485 inhibits the reaction [Gentamicins results in decreased expression of SLC22A8 mRNA], JBP 485 inhibits the reaction [Gentamicins results in decreased expression of SLC22A8 protein] CTD PMID:23707770 gentamycin decreases expression EXP 6480464 Gentamicins results in decreased expression of SLC22A8 mRNA, Gentamicins results in decreased expression of SLC22A8 protein CTD PMID:19967075 , PMID:23707770 glutaric acid increases import ISO RGD:732952 6480464 SLC22A8 protein results in increased import of glutaric acid CTD PMID:28629854 glutaric acid increases activity ISO RGD:732952 6480464 glutaric acid results in increased activity of SLC22A8 protein CTD PMID:28629854 glutaric acid multiple interactions ISO RGD:732952 6480464 glutaric acid promotes the reaction [SLC22A8 protein results in increased import of 6-carboxyfluorescein] CTD PMID:28629854 glycitein increases uptake ISO RGD:732952 6480464 SLC22A8 protein results in increased uptake of glycitein analog CTD PMID:21244849 GW 4064 increases expression ISO RGD:732953 6480464 GW 4064 results in increased expression of SLC22A8 mRNA CTD PMID:26655953 homovanillic acid multiple interactions EXP 6480464 Homovanillic Acid inhibits the reaction [SLC22A8 protein results in increased uptake of estrone sulfate] CTD PMID:10224140 ibuprofen multiple interactions ISO RGD:732953 6480464 Ibuprofen inhibits the reaction [SLC22A8 protein results in increased uptake of p-Aminohippuric Acid] CTD PMID:15100168 ibuprofen multiple interactions ISO RGD:732952 6480464 Ibuprofen inhibits the reaction [SLC22A8 protein affects the transport of estrone sulfate] CTD PMID:11306713 imidacloprid decreases activity ISO RGD:732952 6480464 imidacloprid results in decreased activity of SLC22A8 protein CTD PMID:31364238 imperatorin increases expression ISO RGD:732953 6480464 imperatorin results in increased expression of SLC22A8 protein CTD PMID:22173200 indocyanine green multiple interactions EXP 6480464 Indocyanine Green inhibits the reaction [SLC22A8 protein results in increased uptake of estrone sulfate] CTD PMID:10224140 indometacin multiple interactions ISO RGD:732952 6480464 Indomethacin inhibits the reaction [SLC22A8 protein affects the transport of estrone sulfate] CTD PMID:11306713 indoxyl sulfate multiple interactions ISO RGD:732952 6480464 [Lansoprazole results in decreased activity of SLC22A8 protein] which results in decreased uptake of Indican more ... CTD PMID:36243147 isoimperatorin increases expression ISO RGD:732953 6480464 isoimperatorin results in increased expression of SLC22A8 mRNA, isoimperatorin results in increased expression of SLC22A8 protein CTD PMID:22173200 lansoprazole multiple interactions ISO RGD:732952 6480464 [Lansoprazole results in decreased activity of SLC22A8 protein] which results in decreased uptake of Indican CTD PMID:36243147 lead(II) chloride increases activity ISO RGD:732952 6480464 lead chloride results in increased activity of SLC22A8 protein CTD PMID:28629854 lead(II) chloride multiple interactions ISO RGD:732952 6480464 lead chloride promotes the reaction [SLC22A8 protein results in increased import of 6-carboxyfluorescein] CTD PMID:28629854 linezolid decreases expression EXP 6480464 Linezolid results in decreased expression of SLC22A8 mRNA CTD PMID:21296123 linoleic acid decreases activity ISO RGD:732952 6480464 Linoleic Acid results in decreased activity of SLC22A8 protein CTD PMID:29045746 lipopolysaccharide decreases expression EXP 6480464 Lipopolysaccharides results in decreased expression of SLC22A8 mRNA CTD PMID:15205389 luteolin decreases activity ISO RGD:732952 6480464 Luteolin results in decreased activity of SLC22A8 protein CTD PMID:32159797 mercaptopurine increases transport ISO RGD:732953 6480464 SLC22A8 protein results in increased transport of Mercaptopurine CTD PMID:15100168 Mercuric oxide multiple interactions EXP 6480464 SLC22A8 protein results in increased uptake of [mercuric oxide co-treated with Acetylcysteine] CTD PMID:12606766 mercury atom multiple interactions ISO RGD:732952 6480464 [SLC22A8 gene SNP affects the susceptibility to Mercury] which affects the abundance of Mercury, SLC22A8 gene SNP affects the susceptibility to and affects the abundance of Mercury CTD PMID:23052037 , PMID:32946573 mercury dichloride multiple interactions EXP 6480464 Mercuric Chloride results in decreased expression of and affects the localization of SLC22A8 protein CTD PMID:19533102 mercury dichloride increases expression EXP 6480464 Mercuric Chloride results in increased expression of SLC22A8 protein CTD PMID:30031051 mercury dichloride decreases expression ISO RGD:732953 6480464 Mercuric Chloride results in decreased expression of SLC22A8 mRNA CTD PMID:27720909 mercury dichloride decreases expression EXP 6480464 Mercuric Chloride results in decreased expression of SLC22A8 mRNA CTD PMID:19533102 mercury(0) multiple interactions ISO RGD:732952 6480464 [SLC22A8 gene SNP affects the susceptibility to Mercury] which affects the abundance of Mercury, SLC22A8 gene SNP affects the susceptibility to and affects the abundance of Mercury CTD PMID:23052037 , PMID:32946573 methotrexate multiple interactions EXP 6480464 Leucovorin inhibits the reaction [Methotrexate results in decreased expression of SLC22A8 protein] more ... CTD PMID:16925582 , PMID:35019195 methotrexate increases uptake EXP 6480464 SLC22A8 protein results in increased uptake of Methotrexate CTD PMID:35019195 methotrexate increases response to substance ISO RGD:732952 6480464 SLC22A8 protein results in increased susceptibility to Methotrexate CTD PMID:27377006 methotrexate multiple interactions ISO RGD:732952 6480464 resveratrol inhibits the reaction [SLC22A8 protein results in increased uptake of Methotrexate], rhein metabolite inhibits the reaction [SLC22A8 protein results in increased uptake of Methotrexate] CTD PMID:27377006 , PMID:28890383 methotrexate increases uptake ISO RGD:732952 6480464 SLC22A8 protein results in increased uptake of Methotrexate CTD PMID:16098483 more ... methotrexate affects transport ISO RGD:732952 6480464 SLC22A8 protein affects the transport of Methotrexate CTD PMID:11306713 methotrexate decreases expression EXP 6480464 Methotrexate results in decreased expression of SLC22A8 protein CTD PMID:16925582 methoxsalen increases expression ISO RGD:732953 6480464 Methoxsalen results in increased expression of SLC22A8 protein CTD PMID:22173200 methylmercury chloride decreases expression ISO RGD:732953 6480464 methylmercuric chloride results in decreased expression of SLC22A8 mRNA CTD PMID:27720909 miquelianin increases uptake ISO RGD:732952 6480464 SLC22A8 protein results in increased uptake of quercetin 3-O-glucuronide analog CTD PMID:21244849 miquelianin multiple interactions ISO RGD:732952 6480464 quercetin 3-O-glucuronide analog inhibits the reaction [SLC22A8 protein results in increased transport of 4-carboxyfluorescein], quercetin 3-O-glucuronide inhibits the reaction [SLC22A8 protein results in increased transport of 4-carboxyfluorescein] CTD PMID:21244849 MK 571 multiple interactions ISO RGD:732952 6480464 verlukast inhibits the reaction [SLC22A8 protein results in increased uptake of Enalaprilat] CTD PMID:33007874 N-acetyl-L-cysteine multiple interactions EXP 6480464 SLC22A8 protein results in increased uptake of [mercuric oxide co-treated with Acetylcysteine] CTD PMID:12606766 N-methyl-4-phenylpyridinium increases uptake EXP 6480464 SLC22A8 protein results in increased uptake of 1-Methyl-4-phenylpyridinium CTD PMID:12675912 N-nitrosodiethylamine decreases expression EXP 6480464 Diethylnitrosamine results in decreased expression of SLC22A8 mRNA CTD PMID:19638242 N-nitrosodimethylamine decreases expression EXP 6480464 Dimethylnitrosamine results in decreased expression of SLC22A8 mRNA CTD PMID:25380136 N1'-[2-[[5-[(dimethylamino)methyl]-2-furanyl]methylthio]ethyl]-N1-methyl-2-nitroethene-1,1-diamine increases uptake EXP 6480464 SLC22A8 protein results in increased uptake of Ranitidine CTD PMID:15319347 , PMID:16006492 N1'-[2-[[5-[(dimethylamino)methyl]-2-furanyl]methylthio]ethyl]-N1-methyl-2-nitroethene-1,1-diamine multiple interactions EXP 6480464 Penicillin G inhibits the reaction [SLC22A8 protein results in increased uptake of Ranitidine] more ... CTD PMID:15319347 N1'-[2-[[5-[(dimethylamino)methyl]-2-furanyl]methylthio]ethyl]-N1-methyl-2-nitroethene-1,1-diamine increases uptake ISO RGD:732952 6480464 SLC22A8 protein results in increased uptake of Ranitidine CTD PMID:16006492 nefazodone decreases expression EXP 6480464 nefazodone results in decreased expression of SLC22A8 mRNA CTD PMID:24136188 nimesulide decreases expression EXP 6480464 nimesulide results in decreased expression of SLC22A8 mRNA CTD PMID:24136188 Obtusifolin decreases activity ISO RGD:732952 6480464 obtusifolin results in decreased activity of SLC22A8 protein CTD PMID:29045746 ochratoxin A decreases expression EXP 6480464 ochratoxin A results in decreased expression of SLC22A8 mRNA, ochratoxin A results in decreased expression of SLC22A8 protein CTD PMID:19538982 more ... ochratoxin A increases uptake ISO RGD:732952 6480464 SLC22A8 protein results in increased uptake of ochratoxin A CTD PMID:16098483 ochratoxin A increases uptake EXP 6480464 SLC22A8 protein results in increased uptake of ochratoxin A CTD PMID:10224140 ochratoxin A affects transport ISO RGD:732952 6480464 SLC22A8 protein affects the transport of ochratoxin A CTD PMID:11306713 ochratoxin A increases expression EXP 6480464 ochratoxin A results in increased expression of SLC22A8 mRNA, ochratoxin A results in increased expression of SLC22A8 protein CTD PMID:19538982 , PMID:30120945 omeprazole multiple interactions ISO RGD:732952 6480464 [Omeprazole results in decreased activity of SLC22A8 protein] which results in decreased uptake of Indican CTD PMID:36243147 oroxylin A decreases activity ISO RGD:732952 6480464 5, 7-dihydroxy-6-methoxy-2-phenylchromen-4-one results in decreased activity of SLC22A8 protein CTD PMID:32159797 , PMID:32305507 oroxylin A multiple interactions ISO RGD:732952 6480464 5, 7-dihydroxy-6-methoxy-2-phenylchromen-4-one inhibits the reaction [SLC22A8 protein results in increased uptake of estrone sulfate] CTD PMID:32305507 oxycodone decreases expression EXP 6480464 Oxycodone results in decreased expression of SLC22A8 mRNA CTD PMID:23439660 p-aminohippuric acid multiple interactions ISO RGD:732952 6480464 aristolochic acid I promotes the reaction [SLC22A8 results in increased export of p-Aminohippuric Acid], estrone sulfate promotes the reaction [SLC22A8 results in increased export of p-Aminohippuric Acid] CTD PMID:19643159 p-aminohippuric acid increases uptake EXP 6480464 SLC22A8 protein results in increased uptake of p-Aminohippuric Acid CTD PMID:10224140 p-aminohippuric acid affects transport ISO RGD:732952 6480464 SLC22A8 protein affects the transport of p-Aminohippuric Acid CTD PMID:11306713 p-aminohippuric acid increases uptake ISO RGD:732952 6480464 SLC22A8 protein results in increased uptake of p-Aminohippuric Acid CTD PMID:16098483 , PMID:33007874 p-aminohippuric acid multiple interactions EXP 6480464 p-Aminohippuric Acid inhibits the reaction [SLC22A8 protein results in increased uptake of Cimetidine] CTD PMID:15319347 p-aminohippuric acid increases uptake ISO RGD:732953 6480464 SLC22A8 protein results in increased uptake of p-Aminohippuric Acid CTD PMID:15100168 p-aminohippuric acid multiple interactions ISO RGD:732953 6480464 Cimetidine inhibits the reaction [SLC22A8 protein results in increased uptake of p-Aminohippuric Acid] more ... CTD PMID:15100168 p-aminohippuric acid increases export ISO RGD:732952 6480464 SLC22A8 results in increased export of p-Aminohippuric Acid CTD PMID:19643159 pantoprazole multiple interactions ISO RGD:732952 6480464 [Pantoprazole results in decreased activity of SLC22A8 protein] which results in decreased uptake of Indican CTD PMID:36243147 paracetamol affects expression ISO RGD:732953 6480464 Acetaminophen affects the expression of SLC22A8 mRNA CTD PMID:17562736 PCB138 multiple interactions ISO RGD:732953 6480464 [2 more ... CTD PMID:25510870 perfluorodecanoic acid multiple interactions EXP 6480464 perfluorodecanoic acid inhibits the reaction [SLC22A8 protein results in increased import of estrone sulfate] CTD PMID:19915082 perfluoroheptanoic acid multiple interactions EXP 6480464 perfluoro-n-heptanoic acid inhibits the reaction [SLC22A8 protein results in increased import of estrone sulfate] CTD PMID:19915082 perfluorooctanoic acid affects transport EXP 6480464 SLC22A8 protein affects the transport of perfluorooctanoic acid CTD PMID:11879818 perfluorooctanoic acid increases import EXP 6480464 SLC22A8 protein results in increased import of perfluorooctanoic acid CTD PMID:19915082 perfluorooctanoic acid multiple interactions EXP 6480464 perfluorooctanoic acid inhibits the reaction [SLC22A8 protein results in increased import of estrone sulfate] CTD PMID:19915082 PhIP multiple interactions ISO RGD:732952 6480464 2-amino-1-methyl-6-phenylimidazo(4 more ... CTD PMID:28629854 PhIP decreases activity ISO RGD:732952 6480464 2-amino-1-methyl-6-phenylimidazo(4, 5-b)pyridine results in decreased activity of SLC22A8 protein CTD PMID:28629854 piperonyl butoxide decreases expression EXP 6480464 Piperonyl Butoxide results in decreased expression of SLC22A8 mRNA CTD PMID:22484513 pirinixic acid decreases expression ISO RGD:732953 6480464 pirinixic acid results in decreased expression of SLC22A8 mRNA CTD PMID:20813756 piroxicam multiple interactions EXP 6480464 Piroxicam inhibits the reaction [SLC22A8 protein results in increased uptake of estrone sulfate] CTD PMID:10224140 potassium dichromate decreases expression ISO RGD:732953 6480464 Potassium Dichromate results in decreased expression of SLC22A8 mRNA CTD PMID:23608068 prednisolone multiple interactions EXP 6480464 Prednisolone inhibits the reaction [Freund's Adjuvant results in decreased expression of SLC22A8 mRNA] CTD PMID:21149847 probenecid decreases expression ISO RGD:732952 6480464 Probenecid results in decreased expression of SLC22A8 mRNA, Probenecid results in decreased expression of SLC22A8 protein CTD PMID:23129053 probenecid decreases activity ISO RGD:732952 6480464 Probenecid results in decreased activity of SLC22A8 protein CTD PMID:28629854 more ... probenecid multiple interactions EXP 6480464 [adefovir co-treated with Probenecid co-treated with Cromolyn Sodium] results in increased expression of SLC22A8 protein more ... CTD PMID:10224140 more ... probenecid multiple interactions ISO RGD:732952 6480464 Probenecid inhibits the reaction [[SLC22A8 results in increased uptake of Aristolochic Acids] which results in increased chemical synthesis of 7-(deoxyadenosin-N(6)-yl)aristolactam I] more ... CTD PMID:11306713 more ... prostaglandin E2 increases transport ISO RGD:732953 6480464 SLC22A8 protein results in increased transport of Dinoprostone CTD PMID:15100168 prostaglandin E2 decreases expression EXP 6480464 Dinoprostone results in decreased expression of SLC22A8 protein CTD PMID:19605544 prostaglandin E2 affects transport ISO RGD:732952 6480464 SLC22A8 protein affects the transport of Dinoprostone CTD PMID:11306713 prostaglandin F2alpha increases transport ISO RGD:732953 6480464 SLC22A8 protein results in increased transport of Dinoprost CTD PMID:15100168 psoralen decreases expression ISO RGD:732953 6480464 Ficusin results in decreased expression of SLC22A8 mRNA CTD PMID:22173200 psoralen increases expression ISO RGD:732953 6480464 Ficusin results in increased expression of SLC22A8 protein CTD PMID:22173200 purine-6-thiol increases transport ISO RGD:732953 6480464 SLC22A8 protein results in increased transport of Mercaptopurine CTD PMID:15100168 purines multiple interactions EXP 6480464 Cromolyn Sodium inhibits the reaction [Purines analog results in decreased expression of SLC22A8 protein], Valsartan inhibits the reaction [Purines analog results in decreased expression of SLC22A8 protein] CTD PMID:36464070 purines decreases expression EXP 6480464 Purines analog results in decreased expression of SLC22A8 protein CTD PMID:36464070 quercetin affects expression EXP 6480464 Quercetin affects the expression of SLC22A8 protein CTD PMID:24958931 quercetin decreases activity ISO RGD:732952 6480464 Quercetin results in decreased activity of SLC22A8 protein CTD PMID:32159797 quercetin multiple interactions ISO RGD:732952 6480464 Quercetin inhibits the reaction [SLC22A8 protein results in increased uptake of estrone sulfate] CTD PMID:19605544 quercetin 3-sulfate multiple interactions ISO RGD:732952 6480464 quercetin 3'-sulfate inhibits the reaction [SLC22A8 protein results in increased transport of 4-carboxyfluorescein] CTD PMID:21244849 ranitidine increases uptake ISO RGD:732952 6480464 SLC22A8 protein results in increased uptake of Ranitidine CTD PMID:16006492 ranitidine increases uptake EXP 6480464 SLC22A8 protein results in increased uptake of Ranitidine CTD PMID:15319347 , PMID:16006492 ranitidine multiple interactions EXP 6480464 Penicillin G inhibits the reaction [SLC22A8 protein results in increased uptake of Ranitidine] more ... CTD PMID:15319347 resveratrol affects expression EXP 6480464 resveratrol affects the expression of SLC22A8 protein CTD PMID:24958931 resveratrol multiple interactions ISO RGD:732952 6480464 resveratrol inhibits the reaction [SLC22A8 protein results in increased uptake of Methotrexate], resveratrol inhibits the reaction [SLC22A8 protein results in increased uptake of Penicillin G] CTD PMID:27377006 Rhein multiple interactions ISO RGD:732952 6480464 rhein inhibits the reaction [SLC22A8 protein results in increased uptake of estrone sulfate] more ... CTD PMID:28890383 riddelliine decreases expression EXP 6480464 riddelliine results in decreased expression of SLC22A8 mRNA CTD PMID:18047722 rotenone decreases expression EXP 6480464 Rotenone results in decreased expression of SLC22A8 mRNA CTD PMID:28374803 sodium arsenate multiple interactions ISO RGD:732952 6480464 sodium arsenate promotes the reaction [SLC22A8 protein results in increased import of 6-carboxyfluorescein] CTD PMID:28629854 sodium arsenate increases activity ISO RGD:732952 6480464 sodium arsenate results in increased activity of SLC22A8 protein CTD PMID:28629854 sodium dichromate decreases expression EXP 6480464 sodium bichromate results in decreased expression of SLC22A8 mRNA CTD PMID:25993096 sodium fluoride decreases expression ISO RGD:732953 6480464 Sodium Fluoride results in decreased expression of SLC22A8 mRNA CTD PMID:27862939 Soman decreases expression EXP 6480464 Soman results in decreased expression of SLC22A8 mRNA CTD PMID:19281266 sulforaphane affects expression EXP 6480464 sulforaphane affects the expression of SLC22A8 protein CTD PMID:24958931 taurocholic acid affects transport ISO RGD:732952 6480464 SLC22A8 protein affects the transport of Taurocholic Acid CTD PMID:11306713 tauroursodeoxycholic acid decreases expression EXP 6480464 ursodoxicoltaurine results in decreased expression of SLC22A8 mRNA CTD PMID:15885361 tenofovir disoproxil fumarate increases response to substance ISO RGD:732952 6480464 SLC22A8 protein results in increased susceptibility to Tenofovir CTD PMID:25448811 tenofovir disoproxil fumarate increases import ISO RGD:732952 6480464 SLC22A8 protein results in increased import of Tenofovir CTD PMID:29738843 tenoxicam multiple interactions ISO RGD:732953 6480464 tenoxicam inhibits the reaction [SLC22A8 protein results in increased uptake of p-Aminohippuric Acid] CTD PMID:15100168 testosterone decreases expression ISO RGD:732953 6480464 Testosterone results in decreased expression of SLC22A8 protein CTD PMID:23389457 testosterone decreases expression ISO RGD:732952 6480464 Testosterone results in decreased expression of SLC22A8 mRNA CTD PMID:33359661 tetrachloromethane decreases expression EXP 6480464 Carbon Tetrachloride results in decreased expression of SLC22A8 protein CTD PMID:12629582 , PMID:17544377 tetrachloromethane increases expression EXP 6480464 Carbon Tetrachloride results in increased expression of SLC22A8 mRNA CTD PMID:31150632 tetracycline increases uptake ISO RGD:732952 6480464 SLC22A8 protein results in increased uptake of Tetracycline CTD PMID:11855680 thiacloprid decreases activity ISO RGD:732952 6480464 thiacloprid metabolite results in decreased activity of SLC22A8 protein, thiacloprid results in decreased activity of SLC22A8 protein CTD PMID:31364238 thioacetamide decreases expression EXP 6480464 Thioacetamide results in decreased expression of SLC22A8 mRNA CTD PMID:23411599 , PMID:34492290 titanium dioxide multiple interactions ISO RGD:732953 6480464 [titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of SLC22A8 mRNA CTD PMID:29950665 toluene affects expression EXP 6480464 Toluene affects the expression of SLC22A8 mRNA CTD PMID:18653662 toluene increases expression ISO RGD:732952 6480464 Toluene results in increased expression of SLC22A8 mRNA CTD PMID:26717081 toluene decreases methylation ISO RGD:732952 6480464 Toluene results in decreased methylation of SLC22A8 gene CTD PMID:26717081 toluene increases expression EXP 6480464 Toluene results in increased expression of SLC22A8 mRNA CTD PMID:22967744 tranilast multiple interactions EXP 6480464 tranilast inhibits the reaction [SLC22A8 protein results in increased uptake of Methotrexate], tranilast inhibits the reaction [SLC22A8 protein results in increased uptake of Penicillin G] CTD PMID:35019195 trichloroethene increases expression EXP 6480464 Trichloroethylene results in increased expression of SLC22A8 mRNA CTD PMID:33387578 triphenyl phosphate affects expression EXP 6480464 triphenyl phosphate affects the expression of SLC22A8 mRNA CTD PMID:30589522 ursodeoxycholic acid decreases expression EXP 6480464 Ursodeoxycholic Acid results in decreased expression of SLC22A8 mRNA CTD PMID:15885361 valdecoxib decreases expression EXP 6480464 valdecoxib results in decreased expression of SLC22A8 mRNA CTD PMID:24136188 valproic acid increases methylation ISO RGD:732952 6480464 Valproic Acid results in increased methylation of SLC22A8 gene CTD PMID:29154799 valsartan multiple interactions EXP 6480464 [adefovir co-treated with Probenecid co-treated with Valsartan] results in increased expression of SLC22A8 protein, Valsartan inhibits the reaction [Purines analog results in decreased expression of SLC22A8 protein] CTD PMID:35114312 , PMID:36464070 valsartan increases expression ISO RGD:732952 6480464 Valsartan results in increased expression of SLC22A8 protein CTD PMID:36464070 vancomycin increases expression ISO RGD:732953 6480464 Vancomycin results in increased expression of SLC22A8 mRNA CTD PMID:18930951 vancomycin multiple interactions EXP 6480464 JBP 485 inhibits the reaction [Vancomycin results in decreased expression of SLC22A8 mRNA], JBP 485 inhibits the reaction [Vancomycin results in decreased expression of SLC22A8 protein] CTD PMID:29964132 vancomycin decreases expression EXP 6480464 Vancomycin results in decreased expression of SLC22A8 mRNA, Vancomycin results in decreased expression of SLC22A8 protein CTD PMID:29964132 vanillylmandelic acid multiple interactions EXP 6480464 Vanilmandelic Acid inhibits the reaction [SLC22A8 protein results in increased uptake of estrone sulfate] CTD PMID:10224140 vildagliptin multiple interactions EXP 6480464 Vildagliptin inhibits the reaction [Dietary Fats results in decreased expression of SLC22A8 protein] CTD PMID:34081941 wedelolactone decreases activity ISO RGD:732952 6480464 wedelolactone results in decreased activity of SLC22A8 protein CTD PMID:32159797 wedelolactone multiple interactions ISO RGD:732952 6480464 [wedelolactone results in decreased activity of SLC22A8 protein] which results in increased susceptibility to and results in increased activity of aristolochic acid I CTD PMID:32159797 wogonin decreases activity ISO RGD:732952 6480464 wogonin results in decreased activity of SLC22A8 protein CTD PMID:32159797 wogonin multiple interactions ISO RGD:732952 6480464 [wogonin results in decreased activity of SLC22A8 protein] which results in increased susceptibility to and results in increased activity of aristolochic acid I CTD PMID:32159797