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Gene: Ghsr (growth hormone secretagogue receptor) Rattus norvegicus
Symbol: Ghsr
Name: growth hormone secretagogue receptor
RGD ID: 621397
Description: Exhibits growth hormone secretagogue receptor activity and peptide hormone binding activity. Involved in several processes, including regulation of digestive system process; regulation of secretion by cell; and response to peptide hormone. Localizes to plasma membrane. Used to study middle cerebral artery infarction. Biomarker of isolated growth hormone deficiency; multiple endocrine neoplasia; obstructive sleep apnea; status epilepticus; and transient cerebral ischemia. Human ortholog(s) of this gene implicated in obesity. Orthologous to human GHSR (growth hormone secretagogue receptor); PARTICIPATES IN G protein mediated signaling pathway via Galphaq family; ghrelin system pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,5-hexanedione; ammonium chloride.
Type: protein-coding
Also known as: GH-releasing peptide receptor; ghrelin receptor; GHRP; GHS-R; growth hormone secretagogue receptor type 1
Homo sapiens (human) : GHSR (growth hormone secretagogue receptor)  HGNC  Alliance
Mus musculus (house mouse) : Ghsr (growth hormone secretagogue receptor)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Ghsr (growth hormone secretagogue receptor)
Pan paniscus (bonobo/pygmy chimpanzee) : GHSR (growth hormone secretagogue receptor)
Canis lupus familiaris (dog) : GHSR (growth hormone secretagogue receptor)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Ghsr (growth hormone secretagogue receptor)
Sus scrofa (pig) : GHSR (growth hormone secretagogue receptor)
Chlorocebus sabaeus (African green monkey) : GHSR (growth hormone secretagogue receptor)
Heterocephalus glaber (naked mole-rat) : Ghsr (growth hormone secretagogue receptor)
more info ...
Allele / Splice: Ghsrm1Mcwi   Ghsrm2Mcwi   Ghsrm3Mcwi   Ghsrem1Ottc  
Genetic Models: FHH-Ghsrm1Mcwi SS-Ghsrm2Mcwi SS-Ghsrm3Mcwi W-Ghsrem1Ottc
Is Marker For: Strains:   SD-Tg(Th-Ghsros)  
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.02113,065,953 - 113,071,265 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2113,066,885 - 113,070,261 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02132,784,207 - 132,789,319 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42113,269,623 - 113,272,999 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.12113,214,584 - 113,217,961 (+)NCBI
Celera2105,470,925 - 105,474,301 (+)NCBICelera
Cytogenetic Map2q24NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
QTLs in Region (Rnor_6.0)
Related Rat Strains
Genetic Models
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Ghsr
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 621397
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2020-09-23
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.